Jens Juul Holst

Jens Juul Holst

Professor


  1. 1998
  2. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity. / Deacon, C.F.; Knudsen, L.B.; Madsen, K.; Wiberg, F.C.; Jacobsen, O.; Holst, J.J.

    In: Diabetologia, No. 41, 1998, p. 271-278.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in CHL cells. / Almind, K.; Ambye, Louise; Urhammer, S.A.; Hansen, T.; Echwald, S.M.; Holst, J.J.; Gromada, Jesper Lindgren; Thorens, B.; Pedersen, O.

    In: Diabetologia, No. 41, 1998, p. 1194-1198.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Distal small bowel hormones: Correlation with fasting antroduodenal motility and gastric emptying. / Naslund, E.; Gryback, P.; Backman, L.; Jacobsson, H.; Holst, J.J.; Theodorsson, E.; Hellstrom, P.M.

    In: Dig. Dis. Sci., No. 43, 1998, p. 945-952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia. / Toft-Nielsen, M; Madsbad, Sten; Holst, Jens Juul.

    In: Diabetologia, Vol. 41, No. 10, 1998, p. 1180-1186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling. / Gromada, J; Bokvist, K; Ding, W G; Holst, J J; Nielsen, Jens Høiriis; Rorsman, P.

    In: Diabetes, Vol. 47, No. 1, 1998, p. 57-65.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion. / Porksen, N.; Grøfte, T.; Nyholm, Birgit; Holst, J.J.; Pincus, S.M.; Veldhuis, J.D.; Schmitz, O.; Butler, P.C.

    In: Diabetes, No. 47, 1998, p. 45-49.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. / Flint, A.; Raben, Anne; Astrup, Arne; Holst, Jens Juul.

    In: Journal of Clinical Investigation, Vol. 101, No. 3, 1998, p. 515-520.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Glucagon-like peptide-1 - a new hormone and a new drug. / Holst, J.J.

    In: Ugeskrift for læger, No. 160, 1998, p. 2371-2377.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow. / Wettergren, A.; Wojdemann, M.; Holst, J.J.

    In: Am. J. Physiol., No. 275, 1998, p. G984-G992.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glucagon-like peptide-1 retards gastric emptying and small bowel transit in the rat: Effect mediated through central or enteric nervous mechanisms. / Tolessa, T.; Gutniak, M.K.; Holst, J.J.; Efendic, S.; Hellstrom, P.M.

    In: Dig. Dis. Sci., No. 43, 1998, p. 2284-2290.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Glucagon-like peptide-2 inhibits centrally induced antral motility in pigs. / Wojdemann, M.; Wettergren, A.; Hartmann, Bolette; Holst, J.J.

    In: Scandinavian Journal of Gastroenterology, No. 33, 1998, p. 828-832.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Importance of small bowel peptides for the improved glucose metabolism 20 years after jejunoileal bypass for obesity. / Naslund, E.; Backman, L.; Holst, J.J.; Theodorsson, E.; Hellstrom, P.M.

    In: Obes. Surg., No. 8, 1998, p. 253-260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure. / Nauck, M.A.; Sauerwald, A.; Ritzel, R.; Holst, J.J.; Schmiegel, W.

    In: Diabetes Care, No. 21, 1998, p. 1925-1931.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Inhibition of human gastric lipase secretion by glucagon-like peptide-1. / Wojdemann, M.; Wettergren, A.; Sternby, B.; Holst, J.J.; Larsen, S.; Rehfeld, J.F.; Olsen, O.

    In: Dig. Dis. Sci., No. 43, 1998, p. 799-805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes. / Holst, J.J.; Deacon, C.F.

    In: Diabetes, No. 47, 1998, p. 1663-1670.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Inhibitory effect of glucagon-like peptide-1 on small bowel motility. Fasting but not fed motility inhibited via nitric oxide independently of insulin and somatostatin. / Tolessa, T.; Gutniak, M.K.; Holst, J.J.; Efendic, S.; Hellstrom, P.M.

    In: J. Clin. Invest., No. 102, 1998, p. 764-774.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Normalization of sting glycemia by intravenous GLP-1 (7-36amide) or (7-37) in Type 2 diabetic patients. / Nauck, M.A.; Weber, I.; Bach, I.; Richter, S.H.; Ørskov, C.; Holst, J.J.; Schmiegel, W.

    In: Diabetic Medicine, No. 15, 1998, p. 937-945.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Nutrients of animal origin and function of gut hormones. / Holst, J.J.

    Food and Health: Role of Animal Products. Paris : Elsevier, 1998. p. 13-22.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  20. Published

    Obesity - did anything happen since leptin? / Holst, J.J.

    In: Ugeskrift for læger, No. 160, 1998, p. 1182-1184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1. / Holst, J.J.; Deacon, C.F.; Toft-Nielsen, M.; Bjerre-Knudsen, L.

    In: Annals of the New York Academy of Sciences, No. 865, 1998, p. 336-343.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Overnight GLP-1 normalizes fasting but not daytime plasma glucose levels in NIDDM patients. / Willms, B.; Idowu, K.; Holst, J.J.; Creutzfeldt, W.; Nauck, M.A.

    In: Exp. Clin. Endocrinol. Diabetes, No. 106, 1998, p. 103-107.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients. / Seifarth, C.; Bergmann, Jesper; Holst, J.J.; Ritzel, R.; Schmiegel, W.; Nauck, M.A.

    In: Diabet. Med., No. 15, 1998, p. 485-491.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Regulatory Peptides of the Gut. / Holst, J.J.

    Small Bowel Disorders. Kluwer Academic Publishers, 1998.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  25. Published

    The ethanol augmentation of glucose-induced insulin secretion is abolished by calcium antagonism with nifedipine: No evidence for a role of glucagon-like peptide-1 (GLP-1). / Svartberg, J.; Holst, J.J.; Gutniak, M.K.; Adner, N.

    In: Pancreas, No. 16, 1998, p. 66-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The inhibitory effect of glucagon-like peptide-1 (7-36) amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36) amide. / Wettergren, A.; Wojdemann, M.; Holst, J.J.

    In: Peptides, No. 19, 1998, p. 877-882.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus. / Jensen, P.B.; Blume, N.; Mikkelsen, J.D.; Larsen, P.J.; Jensen, H.I.; Holst, J.J.; Madsen, O.D.

    In: J. Clin. Invest., No. 101, 1998, p. 503-510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Treatment of type 2 diabetes with glucagonlike peptide 1. / Holst, J.J.

    In: Current Opinion in Endocrin. and Diabetes, No. 5, 1998, p. 108-115.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas. / Rasmussen, T N; Bersani, M; Schmidt, P; Thim, L; Kofod, Hans; Jørgensen, P N; Poulsen, S S; Holst, J J.

    In: Pancreas, Vol. 16, No. 2, 03.1998, p. 195-204.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients. / Nauck, M A; Weber, I; Bach, I; Richter, S; Orskov, C; Holst, J J; Schmiegel, W.

    In: Diabetic Medicine Online, Vol. 15, No. 11, 11.1998, p. 937-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 1999
  32. Published

    Advances in non-peptide glucagon receptor antagonist. / Madsen, P.; Knudsen, L.B.; Brand, C.L.; Holst, J.J.

    In: Curr. Pharm Design, No. 5, 1999, p. 683-691.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Continuous subcutaneous infusion of Glucagon-like Peptide-1 (GLP-1) lowers plasma glucose and reduces appetite in type II diabetic patients. / Toft-Nielsen, M.B.; Madsbad, S.; Holst, J.J.

    In: Diabetes Care, No. 22, 1999, p. 1137-1143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Diabetic Intestinal Growth Adaptation and glucagon-like peptide 2 (GLP-2) in the rat. Effect of dietary fibres. / Thulesen, J.; Hartmann, B.; Nielsen, C.; Holst, J.J.; Poulsen, S.S.

    In: Gut, No. 45, 1999, p. 672-678.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Differential effects of saturated and monounsaturated fat on postprandial lipaemia and GIP/GLP-1 response in healthy subjects. / Thomsen, C.; Rasmussen, O.; Lousen, T.; Hermansen, K.; Holst, J.J.

    In: Am. J. Clin. Nutri., No. 69, 1999, p. 1135-1143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Energy intake and appetite is suppressed by glucagon-like peptide-1 (GLP-1) in obese men. / Näslund, E.; Barkeling, B.; King, N.; Gutniak, M.K.; Blundell, J.E.; Holst, J.J.; Rössner, S.; Hellström, P.M.

    In: International Journal of Obesity, No. 23, 1999, p. 304-311.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Fast acting nervous regulation of immunoglobulin A secretion from isolated perfused porcine ileum. / Schmidt, P.T.; Eriksen, L.; Loftager, M.; Rasmussen, T.N.; Holst, J.J.

    In: Gut, No. 45, 1999, p. 679-685.

    Research output: Contribution to journalJournal articleResearch

  38. Published

    Glucagon-like peptide-1 (GLP-1): An intestinal hormone, signalling nutritional abundance, with an unusual therapeutic potential. / Holst, J.J.

    In: Trends in Endocrinology and Metabolism, No. 10, 1999, p. 229-235.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Glucagon-like peptide-1 slows solid gastric emptying and inhibits insulin, glucagon and peptide YY release in humans. / Näslund, E.; Bogefors, J.; Skogar, S.; Grybäck, P.; Jacobsen, H.L.; Holst, J.J.; Helström, P.M.

    In: Am. J. Physiol., No. 277, 1999, p. 910-916.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Glucagon-like peptide-1 suppresses energy expenditure in obese humans. / Flint, A.; Raben, A.; Holst, Jens Juul; Astrup, A.

    International journal of obesity. ed. / J.-P. Després; I. Macdonald. 23. ed. European Association for the Study of Obesity, 1999. p. S35.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  41. Published

    Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells. / Hansen, L.; Deacon, C.F.; Ørskov, C.; Holst, J.J.

    In: Endokrinologiya, No. 140, 1999, p. 5356-5363.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Glucagon-like peptide-1, a gastrointestinal hormone with a pharmaceutical potential. / Holst, J.J.

    In: Current Medicinal Chemistry, No. 6, 1999, p. 1005-1017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Glucagon-like peptide-1: A basis for new approaches to the management of Diabetes. / Deacon, C.F.; Holst, J.J.; Carr, R.D.

    In: Drugs of Today, No. 35, 1999, p. 159-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Hour profiles of insulin, subtrates and gut incretin hormones: Early defects in glucose tolerant offspring of type II (non-insulin dependent) diabetic paitents. / Nyholm, Birgit; Walker, M.J.C.; Gravholdt, C.H.; Alberti, K.G.M.M.; Holst, J.J.; Schmitz, O.

    In: Diabetologia, No. 42, 1999, p. 1314-1323.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Human gastric lipase secretion is inhibited by intraduodenal perfusion of dietary fat. / Wøjdemann, M.; Riber, C.; Bisgaard, T.; Sternby, B.; Larsen, S.; Rehfeld, J.F.; Holst, J.J.; Olesen, O.

    In: Regulatory Peptides, No. 80, 1999, p. 101-106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Impaired meal-stimulated glucagon-like peptide-2 responses in short bowel patients with intestinal failure. / Jeppesen, P.B.; Hansen, B.S.; Hartmann, B.; Holst, J.J.; Mortensen, P.B.

    In: Gut, No. 45, 1999, p. 559-563.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Importance of colonic fermentation in short bowel patients. Small intestinal malabsorption of easily digestible carbohydrate. / Olesen, M.; Gudmand-Høyer, E.; Holst, J.J.; Jørgensen, S.

    In: Dig. Dis. Sci., No. 44, 1999, p. 1914-1923.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Increased Circulating leptin in cirrhosis: relation to release and disposal. / Henriksen, Jens H.; Holst, J.J.; Møller, S.; Brinch, K.; Bendtsen, Flemming.

    In: Hepatology, No. 29, 1999, p. 1818-1824.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Increased intensity of physical activity stimulates subsequent fat intake. / Klausen, B.; Toubro, S.; Ranneries, C.; Rehfeld, J.F.; Holst, J.J.; Christensen, N.J.; Astrup, Arne.

    In: International Journal of Obesity, No. 23, 1999, p. 1282-1287.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Inhibition of dipeptidyl peptidase IV with NVP DPP728 increases plasma GLP-1 (7-36amide) concentrations and improves oral glucose tolerance in obese Zucker rats. / Balkan, B.; Kwasnik, L.; Miserendino, R.; Holst, J.J.; Lie, X.

    In: Diabetologia, No. 42, 1999, p. 1324-1331.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Inhibition of shamfeeding stimulated human gastric acid secretion by glucagon-like peptide-2. / Wøjdemann, M.; Wettergren, A.; Hartmann, B.; Hilsted, L.M.; Holst, J.J.

    In: J. Clin. Endocrinol. Metab., No. 84, 1999, p. 2513-2517.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Octreotide suppresses the incretin GLP-1 in patients with acromegally, clinically nonfunctioning pituitary tumours and in healthy subjects. / Plöckinger, U.; Holst, J.J.; Messerschmidt, D.; Hopfenmüller, W.; Quabbe, H.J.

    In: European Journal of Endocrinology, No. 140, 1999, p. 538-544.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Proglucagon cleavage profile in canine L-cells expressing endogenous PC-1/3 and PC-2. / Damholt, A.B.; Buchan, A.M.J.; Holst, J.J.; Kofod, H.

    In: Endokrinologiya, No. 140, 1999, p. 4800-4808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Selectivity of prandial glucose regulators: nateglinide, but not repaglinide, accelerates exocytosis in rat pancreatic A-cells. / Bokvist, K.; Høy, M.; Buschard, Karsten; Holst, J.J.; Thomsen, M.K.; Gromada, Jesper Lindgren.

    In: Eur. J. Pharmacol., No. 386, 1999, p. 105-111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Tachykinins stimulate acid and pepsinogen secretion in the isolated perfused porcine stomach. / Schmidt, P.T.; Rasmussen, T.N.; Holst, J.J.

    In: Acta Physiologica (Print Edition), No. 166, 1999, p. 335-340.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Tachykinins stimulate the release of peptide hormones (glucagon-like peptide-1), and paracrine - (somatostatin) and neurotransmitters (vasoactive intestinal polypeptide) from porcine ileum through NK-1 receptors. / Schmidt, P.T.; Rickelt, L.F.; Holst, J.J.

    In: Digestive Diseases and Sciences, No. 44, 1999, p. 1273-1281.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    The arcuate nucleus is pivotal in mediating the anorectic effects of centrally administered leptin. / Tang-Christensen, M.; Holst, J.J.; Hartmann, Bolette; Vrang, Niels.

    In: NeuroReport, No. 10, 1999, p. 1183-1187.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans. / Jensen, P.B.; Kristensen, P.; Clausen, J.T.; Judge, M.E.; Hastrup, S.; Thim, Lars; Wulff, B. S.; Foged, C.; Jensen, J.; Holst, J.J.; Madsen, O.D.

    In: FEBS Letters, No. 447, 1999, p. 139-143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1. / Holst, J.J.

    In: Exp. Opin. Invest. Drugs, No. 8, 1999, p. 1409-1415.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Glucagon-like peptide-1 : a basis for new approaches to the management of diabetes. / Deacon, C F; Holst, Jens Juul; Carr, R D.

    In: Drugs of Today, Vol. 35, No. 3, 03.1999, p. 159-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1. / Holst, Jens Juul.

    In: Expert Opinion on Investigational Drugs, Vol. 8, No. 9, 09.1999, p. 1409-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2. / Damholt, A B; Buchan, A M; Holst, J J; Kofod, Hans.

    In: Endocrinology, Vol. 140, No. 10, 10.1999, p. 4800-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat : effects of dietary fibre. / Thulesen, J; Hartmann, B; Nielsen, C; Holst, J J; Poulsen, Steen Seier.

    In: Gut, Vol. 45, No. 5, 11.1999, p. 672-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. / Hansen, L; Deacon, C F; Orskov, C; Holst, J J.

    In: Molecular Endocrinology, Vol. 140, No. 11, 11.1999, p. 5356-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 2000
  66. Published

    1,5-Anhydro fructose increase glucose tolerance by increasing GLP-1 and insulin in mice. / Ahrén, Bo; Holst, J.J.; Marcussen, J.; Yu, S.

    In: Eur. J. Pharmacol., No. 397, 2000, p. 219-225.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Antidiabetogenic action of cholecystokinin in type 2 diabetes. / Ahrén, Bo; Holst, J.J.; Efendic, S.

    In: J. Clin. Endocrinol. Metab., No. 85, 2000, p. 1043-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Circulating levels of incretin hormones an amylin in the fasting state and after oral glucose in growth hormone (GH-)deficient patients before and after GH replacement. A placebo controlled study. / Jørgensen, J.O.L.; Rosenfalck, A.M.; Fisker, S.; Nyholm, B.; Fineman, M.S.; Schmitz, O.; Madsbad, S.; Holst, J.J.; Christiansen, J.S.

    In: European Journal of Endocrinology, No. 143, 2000, p. 593-599.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide. / Deacon, C.F.; Nauck, M.A.; Meier, J.; Hücking, K.; Holst, J.J.

    In: Journal of Clinical Endocrinology and Metabolism, No. 85, 2000, p. 3575-3581.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice. / Hartmann, B; Thulesen, J; Kissow, Hannelouise; Thulesen, S; Orskov, C; Ropke, C; Poulsen, S S; Holst, J J.

    In: Endocrinology, Vol. 141, No. 11, 2000, p. 4013-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Effect of glucagon-like peptide 1 (7-356) amide in insulin treated patients with diabetes mellitus secondary to chronic pancreatitis. / Hedetoft, C.; Larsen, S.; Sheikh, S.; Holst, J.J.

    In: Pancreas, No. 20, 2000, p. 25-31.

    Research output: Contribution to journalJournal articleResearch

  72. Published

    Effect of glucagon-like peptide-1-(7,36)-amide on glucose effectiveness and insulin action in people with type 2 diabetes mellitus. / Vella, A.; Shah, P.; Basu, R.; Basu, A.; Holst, J.J.; Rizza, R.A.

    In: Diabetes, No. 49, 2000, p. 611-617.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Effects of oral glucose on systemic glucose metabolism during hyperinsulinaemic hypoglycemia in normal man. / Poulsen, P.L.; Grøfte, T.; Holck, P.; Møller, J.; Schmitz, O.; Ørskov, L.; Holst, J.J.; Møller, N.

    In: Metabolism, No. 49, 2000, p. 1598-1603.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Elevated circulating leptin in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin. / Henriksen, Jens H.; Holst, J.J.; Møller, S.; Jensen, G.; Bendtsen, Flemming.

    In: Clin.Sci., No. 99, 2000, p. 527-534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Elevated fasting glucagon-like peptide 1 and 2 secretion in ileum-resected short bowel patients with a preserved colon. / Jeppesen, P.B.; Hartmann, Bolette; Hansen, B.S.; Poulsen, Steen Seier; Thulesen, Jesper; Holst, J.J.; Mortensen, Per Brøbech.

    In: Gut, No. 47, 2000, p. 370-376.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Evaluation of ß-cell secretory capacity using glucagon-like peptide-1. / Visbøll, T.; Toft-Nielsen, M.; Krarup, T.; Madsbad, S.; Dinesen, B.; Holst, J.J.

    In: Diabetes Care, No. 23, 2000, p. 807-812.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    GLP-2 stimulates intestinal growth by suppressing proteolysis and apoptosis in TNP-fed premature pigs. / Burrin, D.G.; Stoll, B.; Jiang, R.; Petersen, Y.; Elnif, J.; Buddington, R.K.; Schmidt, M.; Holst, J.J.; Hartmann, B.; Sangild, P.T.

    In: Am. J. Physiol., No. 279, 2000, p. G1249-G1256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Glucose mediated glucose disposal in insulin resistant normoglycemic relatives of type 2 diabetic patients. / Henriksen, J.E.; Levin, K.; Thye-Rønn, Peter; Alford, F.; Hother-Nielsen, Ole; Holst, J.J.; Beck-Nielsen, Henning.

    In: Diabetes, No. 49, 2000, p. 1209-1218.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Gut hormones as pharmaceuticals. From enteroglucagon to GLP-1 and GLP-2. / Holst, J.J.

    In: Review Regul Pept, No. 93, 2000, p. 45-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Improved glucagon tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice. / Ahrén, Bo; Holst, J.J.; Mårtensson, H.; Balkan, B.

    In: Eur. J. Pharmacol., No. 404, 2000, p. 239-245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    In vivo and in vitro degradation of glucagon-like peptide-2 in humans. / Hartmann, Bolette; Harr, M.B.; Jeppesen, P.B.; Wojdemann, M.; Deacon, C.F.; Mortensen, P.B.; Holst, J.J.

    In: Journal of Clinical Endocrinology and Metabolism, No. 85, 2000, p. 2884-2888.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Influence of acarbose on postprandial insulin requirements in patients with type 1 diabetes. / Juntti-Berggren, L.; Pigon, J.; Hellström, P.M.; Holst, J.J.; Efendic, S.

    In: Diab Nutr Metab, No. 13, 2000, p. 7-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Minimal enteral nutrient requirements for intestinal growth in neonatal piglets: how much is enough? / Burrin, D.G.; Stoll, B.; Jiang, R.; Chang, Xiaoquing; Hartmann, B.; Holst, J.J.; Greeley, G.H.; Reeds, P.J.

    In: Am. J. Clin. Nutr., No. 71, 2000, p. 1603-1610.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Neurogenic nitric oxide and exocrine secretion in the gastrointestinal tract. / Ørskov, C.; Holst, J.J.

    Nitric Oxide and the Peripheral Nervous System. London, UK : Portland Press Ltd., 2000. p. 131.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  85. Published

    PACAP 1-38 as neurotransmitter in porcine adrenal glands. / Tornøe, K.; Hannibal, J.; Rickelt, L.F.; Bolding Jensen, M.; Børglum, J.T.; Fahrenkrug, Jan; Holst, J.J.

    In: American Journal of Physiology: Endocrinology and Metabolism, No. 279, 2000, p. E1412-E1425.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    PACAP contributes to insulin secretion after gastric glucose gavage in mice. / Filipsson, K.; Holst, J.J.; Ahrén, Bo.

    In: Am. J. Physiol., No. 279, 2000, p. R424-432.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2. / Thulesen, Jesper; Hartmann, Bolette; Ørskov, C.; Jeppesen, P.B.; Holst, J.J.; Poulsen, Steen Seier.

    In: Peptides, No. 10, 2000, p. 1511-1517.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Regulatory peptides of the gastrointestinal tract. / Holst, J.J.

    Small Bowel Disorders. London : Small Bowel Disorders, 2000. p. 96-115.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  89. Published

    Short-term treatment with GLP-1 increases pulsatile secretion in type 2 diabetes with no effect on orderliness. / Juhl, C.B.; Schmitz, O.; Holst, J.J.; Vedhuis, J.; Pørksen, N.

    In: Diabetologia, No. 43, 2000, p. 583-588.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Somastostatin restrains the secretion of glucagon-like peptide-1 and 2 (GLP-1 and GLP-2) from isolated perfused porcine ileum. / Hansen, L.; Hartmann, Bolette; Bisgaard, T.; Mineo, H.; Jørgensen, P.N.; Holst, J.J.

    In: Am. J. Physiol., No. 278, 2000, p. E1010-E1018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors. / Schmidt, P.T.; Tornøe, K.; Poulsen, Steen Seier; Nygaard, Trine; Holst, Jens Juul.

    In: Pancreas, No. 20, 2000, p. 241-247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Tachykinins in the regulation of gastric motility and secretion. / Schmidt, P.T.; Holst, J.J.

    In: Review Cellular and Molecular Life Sciences, No. 57, 2000, p. 579-588.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans. / Flint, A.; Raben, A.; Rehfeld, J.F.; Holst, J.J.; Astrup, Arne.

    In: International Journal of Obesity, No. 24, 2000, p. 288-298.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Tachykinins in the porcine pancreas : potent exocrine and endocrine effects via NK-1 receptors. / Schmidt, P T; Tornøe, K; Poulsen, Steen Seier; Rasmussen, T N; Holst, J J.

    In: Pancreas, Vol. 20, No. 3, 04.2000, p. 241-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells. / Schmidt, P T; Hartmann, B; Bregenholt, S; Holst, Jens Juul; Claesson, Mogens Helweg.

    In: Scandinavian Journal of Gastroenterology, Vol. 35, No. 5, 01.05.2000, p. 522-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon. / Jeppesen, P B; Hartmann, B; Thulesen, J; Hansen, B S; Holst, J J; Poulsen, Steen Seier; Mortensen, P B.

    In: Gut, Vol. 47, No. 3, 09.2000, p. 370-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat : distribution and binding of i.v. injected (125)I-GLP-2. / Thulesen, J; Hartmann, B; Orskov, C; Jeppesen, P B; Holst, J J; Poulsen, Steen Seier.

    In: Peptides, Vol. 21, No. 10, 10.2000, p. 1511-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. 2001
  99. Published

    Additive glucose-lowering effects of glucagon-like peptide- 1 and metformin type 2 diabetes. / Zander, M.; Taskiran, M.; Toft-Nielsen, M.B.; Holst, J.J.

    In: Diabetes Care, No. 24, 2001, p. 720-725.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Antidiabetogenic action of glucagon-like peptide- 1 related to administration relative to meal intake in subjects with type 2 diabetes. / Gutniak, M.K.; Svartberg, J.; Hellstrom, P.M.; Holst, J.J.

    In: J Intern Med, No. 250, 2001, p. 81-87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Assesment of hepatic insulin action in obese type 2 diabetic patients. / Staehr, P.; Hother-Nielsen, Ole; Levin, K.; Holst, J.J.

    In: Diabetes, No. 50, 2001, p. 1363-1370.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Attenuated processing of proglucagon and glucagon-like peptide- 1 in carboxypeptidase E-deficient mice. / Friis-Hansen, L.; Lacourse, K.A.; Samuelson, L.C.; Holst, J.J.

    In: J. Endocrinol., No. 169, 2001, p. 595-602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Determinants of the effectiveness of glucagon-like peptide- 1 in type 2 diabetes. / Toft-Nielsen, M.B.; Madsbad, S.; Holst, J.J.

    In: J Clin Endocr Metab, No. 86, 2001, p. 3853-3860.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients. / Toft-Nielsen, M B; Damholt, M B; Madsbad, Sten; Hilsted, L M; Hughes, T E; Michelsen, B K; Holst, Jens Juul.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 86, No. 8, 2001, p. 3717-3723.

    Research output: Contribution to journalJournal articleResearchpeer-review

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