Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans. / Nauck, Michael A; Kemmeries, Guido; Holst, Jens Juul; Meier, Juris J.

    In: Diabetes, Vol. 60, No. 5, 2011, p. 1561-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1. / Nauck, Michael A; Walberg, Jörg; Vethacke, Arndt; El-Ouaghlidi, Andrea; Senkal, Metin; Holst, Jens J; Gallwitz, Baptist; Gallwitz, J Baptist; Schmidt, Wolfgang E; Schmiegel, W.

    In: Regulatory Peptides, Vol. 118, No. 1-2, 15.04.2004, p. 89-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and type 2-diabetic patients using exendin [9-39] as a GLP-1 receptor antagonist. / Nauck, Michael A; Kind, J; Köthe, Lars D; Holst, Jens Juul; Deacon, Carolyn F.; Broschag, M; He, YL; Kjems, L; Foley, J.

    In: Diabetes, Vol. 65, No. 8, 2016, p. 2440-2447.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide : A randomized controlled trial in patients with type 2 diabetes. / Nauck, Michael A; Kahle, Melanie; Baranov, Oleg; Deacon, Carolyn F; Holst, Jens J.

    In: Diabetes, Obesity and Metabolism, Vol. 19, No. 2, 06.02.2017, p. 200-207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes. / Nauck, Michael A; El-Ouaghlidi, Andrea; Gabrys, Bartholomäus; Hücking, Katrin; Holst, Jens J; Deacon, Carolyn F; Gallwitz, Baptist; Schmidt, Wolfgang E; Meier, Juris J.

    In: Regulatory Peptides, Vol. 122, No. 3, 2004, p. 209-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. / Nauck, Michael A; Heimesaat, Markus M; Behle, Kai; Holst, Jens Juul; Nauck, Markus S; Ritzel, Robert; Hüfner, Michael; Schmiegel, Wolff H.

    In: The Journal of clinical endocrinology and metabolism, Vol. 87, No. 3, 03.2002, p. 1239-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Preserved incretin activity of glucagon-like peptide 1 (7-36 amide) but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. / Nauck, M.A.; Heimesaat, M.M.; Ørskov, C.; Holst, Jens Juul; Ebert, Reinholdt; Creutzfeldt, W.

    In: Journal of Clinical Investigation, No. 91, 1993, p. 301-307.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effects of glucagon-like peptide-1 (GLP-1) on counterregulatory hormone responses, cognitive functions and insulin secretion during hyperinsulinaemic, stepped hypoglycaemic clamp experiments in healthy volunteers. / Nauck, M.A.; Heimesaat, M.M.; Behle, K.; Holst, J.J.; Nauck, M.S.; Hüfner, M.; Schmiegel, W.H.

    In: J. Clin. Endocrinol. Metab., No. 87, 2002, p. 1239-1246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure. / Nauck, M.A.; Sauerwald, A.; Ritzel, R.; Holst, J.J.; Schmiegel, W.

    In: Diabetes Care, No. 21, 1998, p. 1925-1931.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Normalization of fasting hyperglycaemia by exogenous-glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. / Nauck, M.A.; Kleine, N.; Ørskov, C.; Holst, Jens Juul; Willms, B.; Creutzfeldt, W.

    In: Diabetologia, No. 36, 1993, p. 741-744.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Effects of GLP-1 on gastric and pancreatic exocrine secretion and on gastrointestinal motility. / Nauck, M.A.; Schepp, W.; Holst, J.J.; Schmiegel, W.H.

    The Insulintropic Gut Hormone Glucagon-Like Peptide-1, Front Diabetes vol. 13. Basel : Karger, 1997. p. 194-206.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  12. Published

    Normalization of sting glycemia by intravenous GLP-1 (7-36amide) or (7-37) in Type 2 diabetic patients. / Nauck, M.A.; Weber, I.; Bach, I.; Richter, S.H.; Ørskov, C.; Holst, J.J.; Schmiegel, W.

    In: Diabetic Medicine, No. 15, 1998, p. 937-945.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Glucagon-like peptide-1 (GLP-1) as a new therapeutic approach for type-2 diabetes. / Nauck, M.A.; Holst, Jens Juul; Willms, B.; Schmiegel, W.

    In: Exp. Clin. Endocrinol. Diabetes, No. 105, 1997, p. 187-195.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide-1. / Nauck, M.A.; Walberg, J.; Vethacke, A.; El-Quaghlidi, A.; Senkal, M.; Holst, Jens Juul; Gallwitz, J.B.; Schmidt, W.E.; Schmiegel, W.

    In: Regul. Pept., No. 118, 2004, p. 89-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. / Nauck, M A; Niedereichholz, U; Ettler, R; Holst, J J; Orskov, C; Ritzel, R; Schmiegel, W H.

    In: American Journal of Physiology (Consolidated), Vol. 273, No. 5 Pt 1, 11.1997, p. E981-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM. / Nauck, M A; Wollschläger, D; Werner, J; Holst, J J; Orskov, C; Creutzfeldt, W; Willms, B.

    In: Diabetologia, Vol. 39, No. 12, 12.1996, p. 1546-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients. / Nauck, M A; Weber, I; Bach, I; Richter, S; Orskov, C; Holst, J J; Schmiegel, W.

    In: Diabetic Medicine Online, Vol. 15, No. 11, 11.1998, p. 937-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections. / Nauck, M A; Siemsglüss, J; Orskov, C; Holst, J J.

    In: Zeitschrift fur Gastroenterologie, Vol. 34, No. 3, 03.1996, p. 159-66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes : what is up, what is down? / Nauck, M A; Vardarli, I; Deacon, C F; Holst, Jens Juul; Meier, Joachim.

    In: Diabetologia, Vol. 54, No. 1, 2011, p. 10-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease. / Nathanson, D; Zethelius, B; Berne, C; Holst, Jens Juul; Sjöholm, A; Nyström, T.

    In: Diabetologia, Vol. 53, No. 2, 2009, p. 277-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men. / Nathanson, D; Zethelius, B; Berne, C; Lind, L; Andrén, B; Ingelsson, E; Holst, Jens Juul; Nyström, T.

    In: Diabetic Medicine, Vol. 28, No. 3, 03.2011, p. 301-305.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Distal small bowel hormones: Correlation with fasting antroduodenal motility and gastric emptying. / Naslund, E.; Gryback, P.; Backman, L.; Jacobsson, H.; Holst, J.J.; Theodorsson, E.; Hellstrom, P.M.

    In: Dig. Dis. Sci., No. 43, 1998, p. 945-952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Importance of small bowel peptides for the improved glucose metabolism 20 years after jejunoileal bypass for obesity. / Naslund, E.; Backman, L.; Holst, J.J.; Theodorsson, E.; Hellstrom, P.M.

    In: Obes. Surg., No. 8, 1998, p. 253-260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    GLP-1 inhibits gastric emptying of water but does not influence plasma vasopressin, sodium, or osmolality. / Naslund, E.; Bogefors, J.; Gryback, P.; Holst, J.J.

    In: Scand J Gastroentero, No. 36, 2001, p. 156-162.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glepaglutide, a novel long-acting glucagon-like peptide-2 analogue, for patients with short bowel syndrome : a randomised phase 2 trial. / Naimi, Rahim M; Hvistendahl, Mark; Enevoldsen, Lotte H; Madsen, Jan L; Fuglsang, Stefan; Poulsen, Steen Seier; Kissow, Hannelouise; Pedersen, Jens; Nerup, Nikolaj; Ambrus, Rikard; Achiam, Michael P; Svendsen, Lars B; Holst, Jens Juul; Hartmann, Bolette; Hansen, Svend H; Dragsted, Lars Ove; Steensberg, Adam; Mouritzen, Ulrik; Hansen, Mark B; Jeppesen, Palle Bekker.

    In: The Lancet Gastroenterology and Hepatology, Vol. 4, No. 5, 2019, p. 354-363.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A dose-equivalent comparison of the effects of continuous subcutaneous glucagon-like peptide 2 (GLP-2) infusions versus meal related GLP-2 injections in the treatment of short bowel syndrome (SBS) patients. / Naimi, R M; Madsen, K B; Askov-Hansen, C; Brandt, C F; Hartmann, B; Holst, Jens Juul; Mortensen, P B; Jeppesen, P B.

    In: Regulatory Peptides, Vol. 184, No. 10, 10.06.2013, p. 47-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs. / Nagell, Carl Frederik; Wettergren, André; Ørskov, Cathrine; Holst, Jens Juul.

    In: Scandinavian Journal of Gastroenterology, Vol. 41, No. 6, 2006, p. 667-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The antagonistic metabolite of GLP-1, GLP-1 (9-36)amide, does not influence gastric emptying and hunger sensations in man. / Nagell, Carl Frederic; Pedersen, Jan F; Holst, Jens Juul.

    In: Scandinavian Journal of Gastroenterology, Vol. 42, No. 1, 01.2007, p. 28-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Glucagon-like peptide-2 (GLP-2) inhibits gastric emptying and promotes satiety in man, but is not as potent as Glucagon-like peptide-1 (GLP-1). / Nagell, C.F.; Wettergren, A.; Fog Pedersen, J.; Mortensen, D.; Holst, J.J.

    In: Scandinavian Journal of Gastroenterology, No. 39, 2004, p. 353-358.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Glucagon-like peptide-2 inhibits antral emptying in man, but is not as potent as glucagon-like peptide-1. / Nagell, C F; Wettergren, A; Pedersen, J F; Mortensen, D; Holst, Jens Juul.

    In: Scandinavian Journal of Gastroenterology, Vol. 39, No. 4, 04.2004, p. 353-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal. / Naessén, Sabine; Carlström, Kjell; Holst, Jens Juul; Hellström, Per M; Hirschberg, Angelica L.

    In: American Journal of Clinical Nutrition, Vol. 94, No. 4, 2011, p. 967-972.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Effects of intravenous glucagon-like peptide-1 on glucose control and hemodynamics after coronary artery bypass surgery in patients with type 2 diabetes. / Müssig, Karsten; Oncü, Arzu; Lindauer, Philipp; Heininger, Alexandra; Aebert, Hermann; Unertl, Klaus; Ziemer, Gerhard; Häring, Hans-Ulrich; Holst, Jens Juul; Gallwitz, Baptist.

    In: American Journal of Cardiology, Vol. 102, No. 5, 01.09.2008, p. 646-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion. / Müssig, Karsten; Staiger, Harald; Machicao, Fausto; Kirchhoff, Kerstin; Guthoff, Martina; Schäfer, Silke A; Kantartzis, Konstantinos; Silbernagel, Günther; Stefan, Norbert; Holst, Jens J; Gallwitz, Baptist; Häring, Hans-Ulrich; Fritsche, Andreas.

    In: Diabetes, Vol. 58, No. 7, 2009, p. 1715-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus. / Müssig, Karsten; Staiger, Harald; Machicao, Fausto; Machann, Jürgen; Schick, Fritz; Schäfer, Silke A; Claussen, Claus D; Holst, Jens J; Gallwitz, Baptist; Stefan, Norbert; Fritsche, Andreas; Häring, Hans-Ulrich.

    In: Metabolism - Clinical and Experimental, Vol. 58, No. 12, 2009, p. 1809-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Somostatin and Prosomatostatin-immunoreactive nerve fibers in the bovine pineal gland. / Møller, Morten; Mikkelsen, J.D.; Holst, Jens Juul.

    In: Neuroendocrinology, No. Vol. 56 (2), 1992, p. 278-283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Presence of somatostatin containing neuronal-like cells in the rat pineal gland. / Møller, M.; Holst, Jens Juul; Mikkelsen, J.D.; Webb, S.

    In: Neuroendocrinol. Letters, No. 17, 1995, p. 71-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Somatostatin receptors. / Møller, Lars Neisig; Stidsen, Carsten Enggaard; Hartmann, Bolette; Holst, Jens Juul.

    In: BBA General Subjects, Vol. 1616, No. 1, 2003, p. 1-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test. / Møller, Jonas B; Jusko, William J; Gao, Wei; Hansen, Torben; Pedersen, Oluf; Holst, Jens J; Overgaard, Rune Viig; Madsen, Henrik; Ingwersen, Steen H.

    In: Journal of Pharmacokinetics and Pharmacodynamics, Vol. 38, No. 6, 2011, p. 713-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Glucose-dependent insulinotropic polypeptide (GIP) is associated with lower LDL but unhealthy fat distribution, independent of insulin : The ADDITION-PRO study. / Møller, Cathrine Laustrup; Vistisen, Dorte; Færch, Kristine; Johansen, Nanna Borup; Witte, Daniel R.; Jonsson, Anna; Pedersen, Oluf; Hansen, Torben; Lauritzen, Torsten; Jørgensen, Marit E; Torekov, Signe S; Juul Holst, Jens.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 101, No. 2, 02.2016, p. 485– 493.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Prediction of glycemic index in mixed meals. / Møller, B. K.; Flint, A.; Pedersen, D.; Raben, A. B.; Tetens, I.; Holst, Jens Juul; Astrup, A.

    2003. Paper presented at European Congress on Obesity, International Journal of Obesity, Helsinki, .

    Research output: Contribution to conferencePaperResearch

  41. Published

    Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass : the pathophysiological role of GLP1 and its response to a somatostatin analogue. / Myint, K S; Greenfield, J R; Farooqi, I S; Henning, E; Holst, Jens Juul; Finer, N.

    In: European Journal of Endocrinology, Vol. 166, No. 5, 2012, p. 951-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Effects of intravenous glucagon-like peptide-1 on glucose control and hemodynamics after coronary artery bypass surgery in patients with type 2 diabetes. / Mussig, K.; Oncu, A.; Lindauer, P.; Heininger, A.; Aebert, H.; Unertl, K.; Ziemer, G.; Haring, H.U.; Gallwitz, B.; Holst, Jens Juul.

    In: Journal of the American College of Cardiology, Vol. 102, No. 5, 2008, p. 646-647.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Glucagon-like Peptide-1 and the Central/Peripheral Nervous System : Crosstalk in Diabetes. / Muscogiuri, Giovanna; DeFronzo, Ralph A; Gastaldelli, Amalia; Holst, Jens J.

    In: Trends in Endocrinology and Metabolism, Vol. 28, No. 2, 02.2017, p. 88-103.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Gut : a key player in the pathogenesis of type 2 diabetes? / Muscogiuri, Giovanna; Balercia, Giancarlo; Barrea, Luigi; Cignarelli, Angelo; Giorgino, Francesco; Holst, Jens J; Laudisio, Daniela; Orio, Francesco; Tirabassi, Giacomo; Colao, Annamaria.

    In: Critical Reviews in Food Science and Nutrition, Vol. 58, No. 8, 2018, p. 1294–1309.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Removal of Duodenum Elicits GLP-1 Secretion. / Muscogiuri, Giovanna; Mezza, Teresa; Prioletta, Annamaria; Sorice, Gian Pio; Clemente, Gennaro; Sarno, Gerardo; Nuzzo, Gennaro; Pontecorvi, Alfredo; Holst, Jens Juul; Giaccari, Andrea.

    In: Diabetes Care, Vol. 36, No. 6, 07.02.2013, p. 1641-1646.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance. / Muscelli, Elza; Mari, Andrea; Natali, Andrea; Astiarraga, Brenno D; Camastra, Stefania; Frascerra, Silvia; Holst, Jens Juul; Ferrannini, Ele.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 291, No. 6, 12.2006, p. E1144-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients. / Muscelli, Elza; Mari, Andrea; Casolaro, Arturo; Camastra, Stefania; Seghieri, Giuseppe; Gastaldelli, Amalia; Holst, Jens Juul; Ferrannini, Ele.

    In: Diabetes, Vol. 57, No. 5, 05.2008, p. 1340-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes. / Muscelli, Elza; Casolaro, Arturo; Gastaldelli, Amalia; Mari, Andrea; Seghieri, Giuseppe; Astiarraga, Brenno; Chen, Yu; Alba, Maria; Holst, Jens Juul; Ferrannini, Ele.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 8, 08.2012, p. 2818-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance. / Muscelli, E.; Mari, A.; Natali, A.; Astiarraga, B.D.; Camastra, S.; Frascerra, S.; Holst, J.J.; Ferrannini, E.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 291, No. 6, 2006, p. E1144-E1150.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients. / Muscelli, E.; Mari, A.; Casolaro, A.; Camastra, S.; Seghieri, G.; Gastaldelli, A.; Holst, Jens Juul; Ferrannini, E.

    In: Diabetes, Vol. 57, No. 5, 2008, p. 1340-1348.

    Research output: Contribution to journalJournal articleResearchpeer-review

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