Jens Juul Holst

Jens Juul Holst

Professor


  1. 1995
  2. Published

    Secretion and effects of glucagon-like peptide-1 (GLP-1) in healthy volunteers and NIDDM subjects. / Ørskov, C.; Holst, Jens Juul.

    Diabetes 1994. Elsevier Sci. Intl. Congress Series 1100, 1995. p. 513-516.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  3. 1996
  4. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients : dose-response effects of insulin on glucose turnover. / Christiansen, Erik; Vestergaard, Henrik; Tibell, Annika; Hother-Nielsen, Ole; Holst, Jens Juul; Pedersen, Oluf; Madsbad, Sten.

    In: Diabetes, Vol. 45, No. 9, 1996, p. 1267-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients. / Creutzfeldt, W O; Kleine, N; Willms, B; Orskov, C; Holst, J J; Nauck, M A.

    In: Diabetes Care. Supplement, Vol. 19, No. 6, 06.1996, p. 580-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects. / Holst, J J; Toft-Nielsen, M B; Orskov, C; Nauck, M; Willms, B.

    In: Annals of the New York Academy of Sciences, Vol. 805, 26.12.1996, p. 729-36.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM. / Nauck, M A; Wollschläger, D; Werner, J; Holst, J J; Orskov, C; Creutzfeldt, W; Willms, B.

    In: Diabetologia, Vol. 39, No. 12, 12.1996, p. 1546-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections. / Nauck, M A; Siemsglüss, J; Orskov, C; Holst, J J.

    In: Zeitschrift fur Gastroenterologie, Vol. 34, No. 3, 03.1996, p. 159-66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. / Orskov, C; Poulsen, Steen Seier; Møller, M; Holst, J J.

    In: Diabetes, Vol. 45, No. 6, 06.1996, p. 832-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day. / Orskov, C; Wettergren, A; Holst, J J.

    In: Scandinavian Journal of Gastroenterology, Vol. 31, No. 7, 07.1996, p. 665-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    GLP-1 does not not acutely affect insulin sensitivity in healthy man. / Orskov, L; Holst, J J; Møller, J; Orskov, C; Møller, N; Alberti, K G; Schmitz, O.

    In: Diabetologia, Vol. 39, No. 10, 10.1996, p. 1227-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Positive effects on plasma glucose & appetite by industrial modification of starch. / Raben, A.; Andersen, K.; Karberg, M. A.; Holst, Jens Juul; Astrup, A.

    1996. Poster session presented at 7. European Congress on Obesity, 1996, Barcelona, 6. Nordiska Kongressen i Näringslära, 1996, Göteborg, .

    Research output: Contribution to conferencePosterResearch

  13. Published

    Gastrin release in the fetal lamb in response to luminal infusion of amniotic fluid, milk or GRP. / Sangild, P. T.; Hilsted, L.; Bjørnskov-Bartholdy, L.; Holst, Jens Juul; Trahair, J. F.

    1996. Paper presented at Abstracts from the 11. International Symposium on Regulatory Peptides, .

    Research output: Contribution to conferencePaperResearch

  14. Published

    Tachykinins mediate vagal inhibition of gastrin secretion in pigs. / Schmidt, P; Poulsen, Steen Seier; Hilsted, L; Rasmussen, T N; Holst, J J.

    In: Gastroenterology, Vol. 111, No. 4, 10.1996, p. 925-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1. / Serup, P; Jensen, J; Andersen, F G; Jørgensen, Mette Christine; Blume, N; Holst, Jens Juul; Madsen, O D.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, No. 17, 20.08.1996, p. 9015-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Gastric emptying, glucose responses, and insulin secretion after a liquid test meal : effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. / Willms, B; Werner, J; Holst, J J; Orskov, C; Creutzfeldt, W; Nauck, M A.

    In: Endocrinology, Vol. 81, No. 1, 01.1996, p. 327-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 1997
  18. Published

    Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in non-insulin dependent diabetes mellitus. / Ahrén, Bo; Larsson, H.; Holst, Jens Juul.

    In: J. Clin. Endocrinol. Metab., No. 82, 1997, p. 473-478.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    GIP and GLP-1 after oral glucose in postmenopausal women with impaired glucose tolerance. / Ahrén, Bo; Larsson, H.; Holst, Jens Juul.

    In: European Journal of Endocrinology, No. 137, 1997, p. 127-131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Metabolism of oral glucose in pancreas transplant recipients with normal and impaired glucose tolerance. / Christiansen, E.; Tibell, A.; Vølund, Aa.; Holst, Jens Juul; Rasmussen, K.; Schäffer, L.; Madsbad, S.

    In: J. Clin. Endocrinol. Metab., No. 82, 1997, p. 2299-2307.

    Research output: Contribution to journalJournal articleResearch

  21. Published

    Pituitary adenylate-cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans. / Filipson, K.; Tornøe, K.; Holst, Jens Juul; Ahrén, Bo.

    In: J. Clin. Endocrinol. Metab., No. 82, 1997, p. 3093-3098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Glucagon-like peptide-1 promotes satiety and suppresses energy intake in humans. / Flint, A.; Raben, A.; Holst, Jens Juul; Astrup, A.

    International journal of obesity. 21. ed. European Association for the Study of Obesity, 1997. p. 16.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  23. Published

    Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. / Furuta, M.; Yano, H.; Zhou, A.; Rouille, Y.; Holst, Jens Juul; Carroll, R.; Ravazzolla, M.; Orci, L.; Steiner, D.F.

    In: Proc. Natl. Acad. Sci., No. 94, 1997, p. 6646-6651.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Novel Mody3 Mutations in the Hepatocyte Factor-1a Gene. Evidence for a Hyperexcitabillity of Pancreatic ß-cells to Intravenous Secretagogues in a Glucosetolerant Carrier of a P447L Mutation. / Hansen, T.; Eiberg, Hans Rudolf Lytchoff; Rouard, M.; Vaxillaire, M.; Møller, A.M.; Rasmussen, S.K.; Fridberg, M.; Holst, Jens Juul.

    In: Diabetes, No. 46, 1997, p. 726-730.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Enteroglucagon. / Holst, Jens Juul.

    In: Annual Reviews of Physiology, No. 59, 1997, p. 257-272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Holder GLP-1 som nyt terapeutisk princip i diabetesbehandlingen hvad det lovede? / Holst, Jens Juul.

    In: Tidsskrift for Diabetesbehandling, No. 2(7), 1997, p. 16-22.

    Research output: Contribution to journalJournal articleResearch

  27. Published

    Non-insulin-dependent diabetes mellitus - new drugs? / Holst, Jens Juul.

    In: Drug Discovery Today, No. 2, 1997, p. 128-129.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products. / Holst, Jens Juul; Ørskov, C.; Hartmann, Bolette; Deacon, C.F.

    The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel : Karger, 1997. p. 24-48.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. Published

    The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor. / Holst, Jens Juul; Gromada, Jesper Lindgren; Nauck, M.A.

    In: Diabetologia, No. 40, 1997, p. 984-986.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem. / Larsen, Philip J.; Tang-Christensen, M.; Holst, Jens Juul; Ørskov, C.

    In: Neuroscience, No. Vol. 77, No. 1, 1997, p. 257-270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Glucagon-like peptide-1 (GLP-17-36amide) reduces hepatic glucose production indirectly through changes in insulin and glucagon secretion. / Larsson, H.; Holst, Jens Juul; Ahrén, Bo.

    In: Acta Phys. Scand., No. 160, 1997, p. 413-422.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Altered postprandial motility in chronic pancreatitis: role of malabsorption. / Layer, P.; v.d. Ohe, M.R.; Grandt, D.; Holst, Jens Juul; Jansen, J.B.M.J.; Holtmann, G.; Keller, J.; Goebell, H.

    In: Today in Medicine. Gastroenterology, No. 112, 1997, p. 1624-1634.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. / Nauck, M A; Niedereichholz, U; Ettler, R; Holst, J J; Orskov, C; Ritzel, R; Schmiegel, W H.

    In: American Journal of Physiology (Consolidated), Vol. 273, No. 5 Pt 1, 11.1997, p. E981-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Effects of GLP-1 on gastric and pancreatic exocrine secretion and on gastrointestinal motility. / Nauck, M.A.; Schepp, W.; Holst, J.J.; Schmiegel, W.H.

    The Insulintropic Gut Hormone Glucagon-Like Peptide-1, Front Diabetes vol. 13. Basel : Karger, 1997. p. 194-206.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  35. Published

    Glucagon-like peptide-1 (GLP-1) as a new therapeutic approach for type-2 diabetes. / Nauck, M.A.; Holst, Jens Juul; Willms, B.; Schmiegel, W.

    In: Exp. Clin. Endocrinol. Diabetes, No. 105, 1997, p. 187-195.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity. / Näslund, E.; Grybäck, P.; Hellström, P.M.; Jacobsson, H.; Holst, Jens Juul; Theodorsson, E.; Backmann, L.

    In: International Journal of Obesity, No. 21, 1997, p. 387-392.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Glucose absorption and the release of insulin, gastric inhibitory polypeptide, and glucagon-like peptide-1 in patients after total colectomy. / Palnæs Hansen, C.; Andreassen, Jørn; Holst, Jens Juul.

    In: Scandinavian Journal of Gastroenterology, No. 32, 1997, p. 473-477.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The release of gastric inhibitory peptide, glucagon-like peptide-1, and insulin after oral glucose test in colectomized subjects. / Palnæs Hansen, C.; Andreassen, J.; Holst, J.J.

    In: Scandinavian Journal of Gastroenterology, No. 32, 1997, p. 473-477.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate. / Rasmussen, L.; Qvist, N.; Øster-Jørgensen, E.; Rehfeld, J.F.; Holst, Jens Juul; Pedersen, S.A.

    In: Scandinavian Journal of Gastroenterology, No. 32, 1997, p. 900-905.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Einfluss von subkutanem GLP-1 auf die frühe und langsame Phase der Insulin-sekretion nach intravenöser Glukosebelastung bei gesunden Probanden. / Ritzelt, R.; Ørskov, C.; Holst, Jens Juul; Schmiegel, W.; Nauck, M.A.

    In: Diabetes und Stoffwechsel, No. 6, 1997, p. 64-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Bombesin inhibits histamine release from the rat oxyntic mucosa by a somatostatin-dependent mechanism. / Sandvik, A.K.; Brenna, E.; Sundan, A.; Holst, Jens Juul; Waldum, H.L.

    In: Scandinavian Journal of Gastroenterology, No. 30, 1997, p. 427-432.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Circulating GRP and gastrin in fetal lambs in response to luminal infusion of fluids. / Sangild, P. T.; Hilsted, L.; Bjørnskov-Bartholdy, L.; Holst, Jens Juul; Trahair, J. F.

    1997. Paper presented at Fetal and Neonatal Physiology Symposium, Cambridge, UK, 1997, .

    Research output: Contribution to conferencePaperResearch

  43. Published

    Use of antagonists to define tachykininergic control of intestinal motility in pigs. / Schmidt, Peter; Holst, Jens Juul.

    In: Peptides, No. 18, 1997, p. 373-379.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Effects of glucagon-like peptide-1 (7-36amide) on whole body protein metabolism in healthy man. / Shalev, A.; Holst, Jens Juul; Keller, U.

    In: European Journal of Clinical Investigation, No. 27, 1997, p. 10-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats. / Thulesen, J; Orskov, C; Holst, J J; Poulsen, Steen Seier.

    In: Endocrinology, Vol. 138, No. 1, 01.1997, p. 62-68.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Short term insulin treatment prevents the diabetogenic action of streptozotocin in rats. / Thulesen, Jesper; Ørskov, Cathrine; Holst, Jens Juul; Poulsen, Steen Seier.

    In: Endokrinologiya, No. Vol. 138, No. 1, 1997, p. 62-68.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    PACAP 1-38 as neurotransmitter in the pig pancreas: PACAP-receptor activation revealed by the antagonist PACAP 6-38. / Tornøe, K.; Hannibal, J.; Fahrenkrug, Jan; Holst, J.J.

    In: Am. J. Physiol., No. 273, 1997, p. G436-G446.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Glucagon-like peptide-1 7-36amide and peptide YY have additive inhibitory effects on gastric acid secretion in man. / Wettergren, A.; Maina, P.; Boesby, S.; Holst, Jens Juul.

    In: Scandinavian Journal of Gastroenterology, No. 32, 1997, p. 552-555.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation. / Wettergren, A.; Wøjdemann, M.; Meisner, S.; Stadil, F.; Holst, Jens Juul.

    In: Gut, No. 40, 1997, p. 597-601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 1998
  51. Published

    Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in CHL cells. / Almind, K.; Ambye, Louise; Urhammer, S.A.; Hansen, T.; Echwald, S.M.; Holst, J.J.; Gromada, Jesper Lindgren; Thorens, B.; Pedersen, O.

    In: Diabetologia, No. 41, 1998, p. 1194-1198.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig. / Deacon, C.F.; Hughes, T.E.; Holst, J.J.

    In: Diabetes, No. 47, 1998, p. 764-769.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity. / Deacon, C.F.; Knudsen, L.B.; Madsen, K.; Wiberg, F.C.; Jacobsen, O.; Holst, J.J.

    In: Diabetologia, No. 41, 1998, p. 271-278.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. / Flint, A.; Raben, Anne; Astrup, Arne; Holst, Jens Juul.

    In: Journal of Clinical Investigation, Vol. 101, No. 3, 1998, p. 515-520.

    Research output: Contribution to journalJournal articleResearchpeer-review

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