Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs. / Barkholt, Pernille; Vegge, Andreas; Clausen, Trine Ryberg; Birck, Malene Muusfeldt; Fels, Johannes Josef; Støckel, Mikael; Gögenür, Ismayil; Eriksen, Thomas; Holst, Jens Juul; Hansen, Axel Kornerup; Thymann, Thomas; Jelsing, Jacob; Sangild, Per Torp; Raun, Kirsten.

    In: Journal of Obesity and Bariatrics, Vol. 1, No. 1, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    In vivo efficacy of HD0471953 : A novel GPR119 agonist for the treatment of type 2 diabetes mellitus. / 'T Hart, L. M.; Fritsche, A.; Nijpels, G.; Van Leeuwen, N.; Donnelly, L. A.; Dekker, J. M.; Alssema, M.; Fadista, J.; Carlotti, F.; Gjesing, A. P.; Palmer, C. N.; Van Haeften, T. W.; Herzberg-Schäfer, S. A.; Simonis-Bik, A. M.; Houwing-Duistermaat, J. J.; Helmer, Q.; Deelen, J.; Guigas, B.; Hansen, T.; MacHicao, F.; Willemsen, G.; Heine, R. J.; Kramer, M. H.; Holst, J. J.; De Koning, E. J.; Häring, H. U.; Pedersen, O.; Groop, L.; De Geus, E. J.; Slagboom, P. E.; Boomsma, D. I.; Eekhoff, E. M.; Pearson, E. R.; Diamant, M.

    In: Diabetes Technology & Therapeutics, Vol. 17, 01.02.2015, p. S131-S133.

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. Published

    The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. / 't Hart, Leen M; Fritsche, Andreas; Nijpels, Giel; van Leeuwen, Nienke; Donnelly, Louise A; Dekker, Jacqueline M; Alssema, Marjan; Fadista, Joao; Carlotti, Françoise; Gjesing, Anette P; Palmer, Colin N A; van Haeften, Timon W; Herzberg-Schäfer, Silke A; Simonis-Bik, Annemarie M C; Houwing-Duistermaat, Jeanine J; Helmer, Quinta; Deelen, Joris; Guigas, Bruno; Hansen, Torben; Machicao, Fausto; Willemsen, Gonneke; Heine, Robert J; Kramer, Mark; Holst, Jens Juul; de Koning, Eelco J P; Häring, Hans-Ulrich; Pedersen, Oluf; Groop, Leif; de Geus, Eco J C; Slagboom, P Eline; Boomsma, Dorret I; Eekhoff, Elisabeth M W; Pearson, Ewan R; Diamant, Michaela.

    In: Diabetes, Vol. 62, No. 9, 14.05.2013, p. 3275-3281.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus. / Aaboe, K; Knop, F K; Vilsbøll, T; Deacon, C F; Holst, Jens Juul; Madsbad, S; Krarup, Troels Magelund.

    In: Diabetes, Obesity and Metabolism, Vol. 12, No. 4, 01.04.2010, p. 323-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors. / Aaboe, K.; Akram, S.; Deacon, C. F.; Holst, J. J.; Madsbad, S.; Krarup, T.

    In: Diabetes, Obesity and Metabolism, Vol. 17, No. 1, 01.2015, p. 74-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    GLP-1: physiological effects and potential therapeutic applications. / Aaboe, Kasper; Krarup, Thure; Madsbad, Sten; Holst, Jens Juul; Aaboe, Kasper; Krarup, Thure; Madsbad, Sten; Holst, Jens Juul.

    In: Diabetic Medicine, Vol. 10, No. 11, 2008, p. 994-1003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    GLP-1 : physiological effects and potential therapeutic applications. / Aaboe, Kasper; Krarup, Thure; Madsbad, Sten; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism Online, Vol. 10, No. 11, 11.2008, p. 994-1003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes. / Aaboe, Kasper; Knop, Filip Krag; Vilsbøll, Tina; Vølund, A; Simonsen, U; Deacon, Carolyn F.; Madsbad, Sten; Holst, Jens Juul; Krarup, Thure.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2009, p. 603-608.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes. / Aaboe, Kasper; Knop, Filip Krag; Vilsboll, Tina; Vølund, Aage; Simonsen, Ulf; Deacon, Carolyn F.; Madsbad, Sten; Holst, Jens Juul; Krarup, Thure.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2008, p. 603-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published
  12. Published

    Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets. / Adriaenssens, Alice E; Svendsen, Berit; Lam, Brian Y H; Yeo, Giles S H; Holst, Jens J; Reimann, Frank; Gribble, Fiona M.

    In: Diabetologia, Vol. 59, No. 10, 10.2016, p. 2156-2165.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Characterization of GLP-1 effects on beta cell function after meal ingestion in humans. / Ahren, B.; Holst, Jens Juul; Mari, A.

    In: Diabetes Care, No. 26, 2003, p. 2860-2864.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Comparison of Glycomacropeptide with Phenylalanine Free-Synthetic Amino Acids in Test Meals to PKU Patients : No Significant Differences in Biomarkers, Including Plasma Phe Levels. / Ahring, Kirsten K.; Lund, Allan M.; Jensen, Erik; Jensen, Thomas G.; Brondum-Nielsen, Karen; Pedersen, Michael; Bardow, Allan; Holst, Jens Juul; Rehfeld, Jens F.; Moller, Lisbeth B.

    In: Journal of Nutrition and Metabolism, Vol. 2018, 6352919, 2018, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1. / Ahrén, B; Adner, N; Svartberg, J; Petrella, E; Holst, Jens Juul; Gutniak, M K.

    In: Diabetic Medicine, Vol. 19, No. 9, 09.2002, p. 790-2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    GIP and GLP-1 after oral glucose in postmenopausal women with impaired glucose tolerance. / Ahrén, Bo; Larsson, H.; Holst, Jens Juul.

    In: European Journal of Endocrinology, No. 137, 1997, p. 127-131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Antidiabetogenic action of cholecystokinin in type 2 diabetes. / Ahrén, Bo; Holst, J.J.; Efendic, S.

    In: J. Clin. Endocrinol. Metab., No. 85, 2000, p. 1043-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia. / Ahrén, Bo; Holst, J.J.

    In: Diabetes, No. 50, 2001, p. 1030-1038.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans. / Ahrén, Bo; Holst, Jens Juul; Mari, Andrea.

    In: Diabetes Care. Supplement, Vol. 26, No. 10, 10.2003, p. 2860-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in non-insulin dependent diabetes mellitus. / Ahrén, Bo; Larsson, H.; Holst, Jens Juul.

    In: J. Clin. Endocrinol. Metab., No. 82, 1997, p. 473-478.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    1,5-Anhydro fructose increase glucose tolerance by increasing GLP-1 and insulin in mice. / Ahrén, Bo; Holst, J.J.; Marcussen, J.; Yu, S.

    In: Eur. J. Pharmacol., No. 397, 2000, p. 219-225.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Improved glucagon tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice. / Ahrén, Bo; Holst, J.J.; Mårtensson, H.; Balkan, B.

    In: Eur. J. Pharmacol., No. 404, 2000, p. 239-245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production. / Albrechtsen, Nicolai J. Wewer; Kuhre, Rune E.; Hornburg, Daniel; Jensen, Christian Z.; Hornum, Mads; Dirksen, Carsten; Svane, Maria; Gasbjerg, Laerke S.; Jorgensen, Nils B.; Gabe, Maria N.; Balk-Moller, Emilie; Albrechtsen, Reidar; Winther-Sorensen, Marie; Galsgaard, Katrine D.; Meissner, Felix; Jorsal, Tina; Lund, Asger; Vilsboll, Tina; Eliasen, Rasmus; Bojsen-Moller, Kirstine N.; Idorn, Thomas; Deacon, Carolyn F.; Knop, Filip K.; Rosenkilde, Mette M.; Hartmann, Bolette; Feldt-Rasmussen, Bo; Mann, Matthias; Madsbad, Sten; Holst, Jens J.

    In: Cell Reports, Vol. 21, No. 6, 11.2017, p. 1452-1460.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA : nonspecific interference or truly elevated levels? / Albrechtsen, Nicolai Jacob Wewer; Hartmann, Bolette; Veedfald, Simon; Windeløv, Johanne A; Plamboeck, Astrid; Bojsen-Møller, Kirstine N; Idorn, Thomas; Feldt-Rasmussen, Bo; Knop, Filip K; Vilsbøll, Tina; Madsbad, Sten; Deacon, Carolyn F; Holst, Jens J.

    In: Diabetologia, Vol. 57, No. 9, 03.06.2014, p. 1919-1926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Stability of glucagon-like peptide-1 and glucagon in human plasma. / Albrechtsen, Nicolai Jacob Wewer; Bak, Monika Judyta; Hartmann, Bolette; Christensen, Louise Wulff; Kuhre, Rune E; Deacon, Carolyn; Holst, Jens Juul.

    In: Endocrine Connections, Vol. 4, No. 1, 16.01.2015, p. 50-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

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