Jens Juul Holst

Jens Juul Holst

Professor


  1. 2014
  2. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial. / Idorn, T.; Knop, F. K.; Jorgensen, M. B.; Jensen, T.; Resuli, M.; Hansen, P. M.; Christensen, Karl Bang; Holst, J. J.; Hornum, M.; Feldt-Rasmussen, B.

    In: Diabetologia, Vol. 57, No. 1 supplement, 909, 09.2014, p. S370-S371.

    Research output: Contribution to journalConference abstract in journal

  3. Published

    Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease. / Idorn, Thomas; Knop, Filip K; Jørgensen, Morten B; Christensen, Mikkel; Holst, Jens Juul; Hornum, Mads; Feldt-Rasmussen, Bo.

    In: The Journal of clinical endocrinology and metabolism, Vol. 99, No. 7, jc20133809, 08.04.2014, p. 2457-66.

    Research output: Contribution to journalJournal article

  4. Published

    Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease. / Idorn, Thomas; Knop, Filip K; Jørgensen, Morten; Holst, Jens Juul; Hornum, Mads; Feldt-Rasmussen, Bo.

    In: Nephrology, Dialysis, Transplantation, Vol. 29, No. 1, 01.2014, p. 119-27.

    Research output: Contribution to journalJournal article

  5. Published

    The authors reply. / Idorn, Thomas; Knop, Filip K; Jørgensen, Morten; Holst, Jens Juul; Hornum, Mads; Feldt-Rasmussen, Bo.

    In: Kidney International, Vol. 85, No. 1, 01.2014, p. 212-3.

    Research output: Contribution to journalLetter

  6. Published

    Therapies for inter-relating diabetes and obesity - GLP-1 and obesity. / Iepsen, Eva Pers Winning; Torekov, Signe S; Holst, Jens Juul.

    In: Expert Opinion on Pharmacotherapy, Vol. 15, No. 17, 12.2014, p. 2487-500.

    Research output: Contribution to journalJournal article

  7. Published

    High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals. / Itoh, Kazue; Moriguchi, Ririko; Yamada, Yuichiro; Fujita, Misuzu; Yamato, Takako; Oumi, Masayo; Holst, Jens Juul; Seino, Yutaka.

    In: Nutrition Research, Vol. 34, No. 8, 08.2014, p. 653-60.

    Research output: Contribution to journalJournal article

  8. Published

    Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes : Action LADA 8. / Juhl, C B; Bradley, U; Holst, Jens Juul; Leslie, R D; Yderstraede, K B; Hunter, S; Action LADA Consortium.

    In: Diabetic Medicine, Vol. 31, No. 8, 15.03.2014, p. 941-945.

    Research output: Contribution to journalJournal article

  9. Published

    A 25-year-old woman with type 2 diabetes and liver disease. / Junker, Anders Ellekær; Gluud, Lise Lotte; Pedersen, Jens; Langhoff, Jill Levin; Holst, Jens Juul; Knop, Filip Krag; Vilsbøll, Tina.

    In: Case Reports in Gastroenterology, Vol. 8, No. 3, 2014, p. 398-403.

    Research output: Contribution to journalJournal article

  10. Published

    Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes : a randomised controlled trial. / Karstoft, Kristian; Winding, Kamilla; Knudsen, Sine H.; James, Noemi G.; Scheel, Maria M.; Olesen, Jesper; Holst, Jens Juul; Pedersen, Bente Klarlund; Solomon, Thomas.

    In: Diabetologia, Vol. 57, No. 10, 2014, p. 2081-2093.

    Research output: Contribution to journalJournal article

  11. Published

    Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1 : a case report. / Knop, Filip K; Lund, Asger; Madsbad, Sten; Holst, Jens Juul; Krarup, Thure; Vilsbøll, Tina.

    In: BMC Research Notes, Vol. 7, 326, 2014, p. 1-6.

    Research output: Contribution to journalJournal article

  12. Published

    Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans. / Kuhre, Rune Ehrenreich; Gribble, Fiona M; Hartmann, Bolette; Reimann, Frank; Windeløv, Johanne A; Rehfeld, Jens F; Holst, Jens Juul.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 306, No. 7, 01.04.2014, p. G622-30.

    Research output: Contribution to journalJournal article

  13. Published
  14. Published

    Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation. / Kuhre, Rune Ehrenreich; Frost, Charlotte Rasmussen; Svendsen, Berit; Holst, Jens Juul.

    In: Diabetes, Vol. 63, No. suppl 1, Abstract no 1915-P, 06.2014, p. A491.

    Research output: Contribution to journalConference abstract in journal

  15. Published

    Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial. / Larsen, Julie Rask; Vedtofte, Louise; Holst, Jens Juul; Oturai, Peter; Kjær, Andreas; Corell, Christoph U; Vilsbøll, Tina; Fink-Jensen, Anders.

    In: B M J Open, Vol. 4, No. 3, e004227, 2014, p. 1-9.

    Research output: Contribution to journalJournal article

  16. Published

    The incretin effect does not differ in trained and untrained, young, healthy men. / Lund, Michael Taulo; Dalby, Sina; Hartmann, Bolette; Helge, Jørn Wulff; Holst, Jens Juul; Dela, Flemming.

    In: Acta Physiologica, Vol. 210, No. 3, 03.2014, p. 565-72.

    Research output: Contribution to journalJournal article

  17. Published

    GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery. / Madsbad, Sten; Holst, Jens Juul.

    In: Diabetes, Vol. 63, No. 10, 10.2014, p. 3172-4.

    Research output: Contribution to journalJournal article

  18. Published

    Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery. / Madsbad, Sten; Dirksen, Carsten; Holst, Jens Juul.

    In: The Lancet Diabetes & Endocrinology, Vol. 2, No. 2, 02.2014, p. 152-64.

    Research output: Contribution to journalJournal article

  19. Published

    Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women. / Mark, Alicja Budek; Poulsen, Malene Wibe; Andersen, Stine; Andersen, Jeanette Marker; Bak, Monika Judyta; Ritz, Christian; Holst, Jens Juul; Nielsen, John; de Courten, Barbora; Dragsted, Lars Ove; Bügel, Susanne Gjedsted.

    In: Diabetes Care, Vol. 37, No. 1, 2014, p. 88-95.

    Research output: Contribution to journalJournal article

  20. Published

    GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance. / Matikainen, Niina; Bogl, Leonie H; Hakkarainen, Antti; Lundbom, Jesper; Lundbom, Nina; Kaprio, Jaakko; Rissanen, Aila; Holst, Jens Juul; Pietiläinen, Kirsi H.

    In: Diabetes Care, Vol. 37, No. 1, 01.2014, p. 242-51.

    Research output: Contribution to journalJournal article

  21. Published

    Insulin resistance alters islet morphology in nondiabetic humans. / Mezza, Teresa; Muscogiuri, Giovanna; Sorice, Gian Pio; Clemente, Gennaro; Hu, Jiang; Pontecorvi, Alfredo; Holst, Jens Juul; Giaccari, Andrea; Kulkarni, Rohit N.

    In: Diabetes, Vol. 63, No. 3, 03.2014, p. 994-1007.

    Research output: Contribution to journalJournal article

  22. Published

    Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans. / Nissen, Anne; Christensen, Mikkel; Knop, Filip K; Vilsbøll, Tina; Holst, Jens Juul; Hartmann, Bolette.

    In: The Journal of clinical endocrinology and metabolism, Vol. 99, No. 11, 11.2014, p. E2325-9.

    Research output: Contribution to journalJournal article

  23. Published
  24. Published

    Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3. / Ostoft, Signe H; Bagger, Jonatan I; Hansen, Torben; Pedersen, Oluf; Holst, Jens Juul; Knop, Filip K; Vilsbøll, Tina.

    In: Diabetes, Vol. 63, No. 8, 27.03.2014, p. 2838-44.

    Research output: Contribution to journalJournal article

  25. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo. / Panaro, Brandon L; Tough, Iain R; Engelstoft, Maja S; Matthews, Robert T; Digby, Gregory J; Møller, Cathrine L; Svendsen, Berit; Gribble, Fiona; Reimann, Frank; Holst, Jens Juul; Holst, Birgitte; Schwartz, Thue W; Cox, Helen M; Cone, Roger D.

    In: Cell Metabolism, Vol. 20, No. 6, 02.12.2014, p. 1018-29.

    Research output: Contribution to journalJournal article

  26. Published

    Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes. / Pietraszek, A; Gregersen, S; Pedersen, S B; Holst, Jens Juul; Hermansen, K.

    In: European Journal of Clinical Nutrition, Vol. 68, 14.05.2014, p. 1022-28.

    Research output: Contribution to journalJournal article

  27. Published

    Effect of dietary advanced glycation end products on postprandial appetite, inflammation, and endothelial activation in healthy overweight individuals. / Poulsen, Malene Wibe; Bak, Monika Judyta; Andersen, Jeanette Marker; Monošík, Rastislav; Giraudi-Futin, Anne C; Holst, Jens Juul; Nielsen, John; Lauritzen, Lotte; Larsen, Lesli Hingstrup; Bügel, Susanne Gjedsted; Dragsted, Lars Ove.

    In: European Journal of Nutrition, Vol. 53, No. 2, 2014, p. 661-672.

    Research output: Contribution to journalJournal article

  28. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects. / Rhee, Nicolai Alexander; Østoft, Signe Harring; Holst, Jens Juul; Deacon, Carolyn; Vilsbøll, Tina; Knop, Filip Krag.

    In: European Journal of Endocrinology, Vol. 171, No. 3, 16.06.2014, p. 353-362.

    Research output: Contribution to journalJournal article

  29. Published

    The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract. / Rhee, Nicolai Alexander; Vilmann, Peter; Hassan, Hazem; Hendel, Jakob Westergren; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip Krag.

    In: Scandinavian Journal of Gastroenterology, Vol. 49, No. 9, 09.2014, p. 1143-1149.

    Research output: Contribution to journalJournal article

  30. Published

    Glycemic effects and safety of L-Glutamine supplementation with or without sitagliptin in type 2 diabetes patients-a randomized study. / Samocha-Bonet, Dorit; Chisholm, Donald J; Gribble, Fiona M; Coster, Adelle C F; Carpenter, Kevin H; Jones, Graham R D; Holst, Jens Juul; Greenfield, Jerry R.

    In: PloS one, Vol. 9, No. 11, e113366, 2014, p. 1-7.

    Research output: Contribution to journalJournal article

  31. Published

    Effects of PYY3-36 and GLP-1 on energy intake, energy expenditure and appetite in overweight men. / Schmidt, Julie Berg; Gregersen, Nikolaj Ture; Pedersen, Sue D; Arentoft, Johanne L; Ritz, Christian; Schwartz, Thue W.; Holst, Jens Juul; Astrup, Arne; Sjödin, Anders Mikael.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 306, No. 11, 2014, p. E1248-E1256.

    Research output: Contribution to journalJournal article

  32. Published

    Effects of chronic glucagon-like peptide-2 therapy during weaning in neonatal pigs. / Sigalet, David L; de Heuvel, Elaine; Wallace, Laurie; Bulloch, Estrella; Turner, Justine; Wales, Paul W; Nation, Patrick; Wizzard, Pamela R; Hartmann, Bolette; Assad, Meena; Holst, Jens Juul.

    In: Regulatory Peptides, Vol. 188, 10.01.2014, p. 70-80.

    Research output: Contribution to journalJournal article

  33. Published

    GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle. / Sjøberg, Kim Anker; Holst, Jens Juul; Rattigan, Stephen; Richter, Erik; Kiens, Bente.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 306, No. 4, 2014, p. E355-E362.

    Research output: Contribution to journalJournal article

  34. Published

    Glucagon-like peptide-1: effect on pro-atrial natriuretic peptide in healthy males. / Skov, Jeppe; Holst, Jens Juul; Gøtze, Jens Peter; Frøkiær, Jørgen; Christiansen, Jens Sandahl.

    In: Endocrine Connections, Vol. 3, No. 1, 2014, p. 11-6.

    Research output: Contribution to journalJournal article

  35. Published

    On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes. / Sonne, David P; Lund, Asger; Faber, Jens; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip K.

    In: Endocrine Connections, Vol. 3, No. 4, 12.2014, p. 193-9.

    Research output: Contribution to journalJournal article

  36. Published

    Postprandial gallbladder emptying in patients with type 2 diabetes : potential implications for bile-induced secretion of glucagon-like peptide 1. / Sonne, David P; Rehfeld, Jens F; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip K.

    In: European Journal of Endocrinology, Vol. 171, No. 4, 10.2014, p. 407-419.

    Research output: Contribution to journalJournal article

  37. Published

    Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model. / Sueyoshi, Ryo; Ignatoski, Kathleen M Woods; Okawada, Manabu; Hartmann, Bolette; Holst, Jens Juul; Teitelbaum, Daniel H.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 307, No. 4, 26.06.2014, p. G410-19.

    Research output: Contribution to journalJournal article

  38. Published

    Impact of the reconstruction method on delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy : a prospective randomized study. / Tamandl, Dietmar; Sahora, Klaus; Prucker, Johannes; Schmid, Rainer; Holst, Jens-Juul; Miholic, Johannes; Goetzinger, Peter; Gnant, Michael; Holst, Jens Juul.

    In: World Journal of Surgery, Vol. 38, No. 2, 02.2014, p. 465-75.

    Research output: Contribution to journalJournal article

  39. Published

    Glucagon-like peptide 2 treatment may improve intestinal adaptation during weaning. / Thymann, Thomas; Le Huërou-Luron, I; Petersen, Y M; Hedemann, Mette Skou; Elinf, J; Jensen, B B; Holst, Jens Juul; Hartmann, Bolette; Sangild, Per Torp.

    In: Journal of Animal Science, Vol. 92, No. 5, 2014, p. 2070-2079.

    Research output: Contribution to journalJournal article

  40. Published

    KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia. / Torekov, Signe S; Iepsen, Eva; Christiansen, Michael; Linneberg, Allan; Pedersen, Oluf; Holst, Jens J; Kanters, Jørgen K.; Hansen, Torben.

    In: Diabetes, Vol. 63, No. 4, 04.2014, p. 1315-1325.

    Research output: Contribution to journalJournal article

  41. Published

    A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk. / Torekov, Signe Sørensen; Harsløf, T; Rejnmark, L; Eiken, P; Jensen, J B; Herman, A P; Hansen, T; Pedersen, O; Holst, J J; Langdahl, B L.

    In: The Journal of clinical endocrinology and metabolism, Vol. 99, No. 4, 04.2014, p. E729-33.

    Research output: Contribution to journalJournal article

  42. Published
  43. Published

    Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose. / Vardarli, Irfan; Arndt, Elisabeth; Deacon, Carolyn F; Holst, Jens Juul; Nauck, Michael A.

    In: Diabetes, Vol. 63, No. 2, 02.2014, p. 663-74.

    Research output: Contribution to journalJournal article

  44. Published

    Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity. / Vrieze, Anne; Out, Carolien; Fuentes, Susana; Jonker, Lisanne; Reuling, Isaie; Kootte, Ruud S; van Nood, Els; Holleman, Frits; Knaapen, Max; Romijn, Johannes A; Soeters, Maarten R; Blaak, Ellen E; Dallinga-Thie, Geesje M; Reijnders, Dorien; Ackermans, Mariëtte T; Serlie, Mireille J; Knop, Filip K; Holst, Jens Juul; van der Ley, Claude; Kema, Ido P; Zoetendal, Erwin G; de Vos, Willem M; Hoekstra, Joost B L; Stroes, Erik S; Groen, Albert K; Nieuwdorp, Max.

    In: Journal of Hepatology, Vol. 60, No. 4, 04.2014, p. 824-31.

    Research output: Contribution to journalJournal article

  45. Published

    Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition. / Xiao, Weidong; Feng, Yongjia; Holst, Jens Juul; Hartmann, Bolette; Yang, Hua; Teitelbaum, Daniel H.

    In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, No. 5, 05.2014, p. 2073-87.

    Research output: Contribution to journalJournal article

  46. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance. / van Poppel, P C M; van Asseldonk, E J P; Holst, Jens Juul; Vilsbøll, Tina ; Netea, M G; Tack, C J.

    In: Diabetes, Obesity and Metabolism, Vol. 16, No. 12, 12.2014, p. 1269-73.

    Research output: Contribution to journalLetter

  47. 2013
  48. Published

    The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. / 't Hart, Leen M; Fritsche, Andreas; Nijpels, Giel; van Leeuwen, Nienke; Donnelly, Louise A; Dekker, Jacqueline M; Alssema, Marjan; Fadista, Joao; Carlotti, Françoise; Gjesing, Anette P; Palmer, Colin N A; van Haeften, Timon W; Herzberg-Schäfer, Silke A; Simonis-Bik, Annemarie M C; Houwing-Duistermaat, Jeanine J; Helmer, Quinta; Deelen, Joris; Guigas, Bruno; Hansen, Torben; Machicao, Fausto; Willemsen, Gonneke; Heine, Robert J; Kramer, Mark; Holst, Jens Juul; de Koning, Eelco J P; Häring, Hans-Ulrich; Pedersen, Oluf; Groop, Leif; de Geus, Eco J C; Slagboom, P Eline; Boomsma, Dorret I; Eekhoff, Elisabeth M W; Pearson, Ewan R; Diamant, Michaela.

    In: Diabetes, Vol. 62, No. 9, 14.05.2013, p. 3275-3281.

    Research output: Contribution to journalJournal article

  49. Published

    Preserved GLP-1 and exaggerated GIP secretion in type 2 diabetes and relationships with triglycerides and ALT. / Alssema, Marjan; Rijkelijkhuizen, Josina M; Holst, Jens Juul; Teerlink, Tom; Scheffer, Peter G; Eekhoff, Elisabeth M W; Gastaldelli, Amalia; Mari, Andrea; Hart, Leen M't; Nijpels, Giel; Dekker, Jacqueline M.

    In: European Journal of Endocrinology, Vol. 169, No. 4, 10.2013, p. 421-30.

    Research output: Contribution to journalJournal article

  50. Published

    Effect of glucagon-like peptide-2 exposure on bone resorption : Effectiveness of high concentration versus prolonged exposure. / Askov-Hansen, Carsten; Jeppesen, Palle B; Lund, Pernille; Hartmann, Bolette; Holst, Jens Juul; Henriksen, Dennis B.

    In: Regulatory Peptides, Vol. 181, 10.02.2013, p. 4-8.

    Research output: Contribution to journalJournal article

  51. Published

    Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects. / Asmar, M; Simonsen, L; Arngrim, N; Holst, J J; Dela, F; Bülow, Jens.

    In: International journal of obesity (2005), Vol. 38, No. 2, 2013, p. 259-65.

    Research output: Contribution to journalJournal article

  52. Published

    Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young. / Bagger, J. I.; Ostoft, S. H.; Hansen, T.; Pedersen, O.; Holst, J. J.; Knop, F. K.; Vilsboll, T.

    In: Diabetologia, Vol. 56, 2013, p. S152-S152.

    Research output: Contribution to journalJournal article

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