Jens Juul Holst

Jens Juul Holst

Professor


  1. 2013
  2. Published

    Glucagon-like peptide-1 (GLP-1) : effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men. / Skov, Jeppe; Dejgaard, Anders; Frøkiær, Jørgen; Holst, Jens Juul; Jonassen, Thomas; Rittig, Søren; Christiansen, Jens Sandahl.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 98, No. 4, 04.2013, p. E664-71.

    Research output: Contribution to journalJournal article

  3. Published

    The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release. / Smajilovic, Sanela; Clemmensen, Christoffer; Johansen, Lars Dan; Wellendorph, Petrine; Holst, Jens Juul; Thams, Peter Grevsen; Ogo, Egbuna; Bräuner-Osborne, Hans.

    In: Amino Acids, Vol. 44, No. 2, 2013, p. 383-390.

    Research output: Contribution to journalJournal article

  4. Published

    Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients. / Sonne, David P; Hare, Kristine J; Martens, Pernille; Rehfeld, Jens F; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip K.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 304, No. 4, 15.02.2013, p. G413-9.

    Research output: Contribution to journalJournal article

  5. Published

    Contribution of gastroenteropancreatic appetite hormones to protein-induced satiety. / Sparre, Anita Belza; Ritz, Christian; Sørensen, Mejse Q; Holst, Jens Juul; Rehfeld, Jens Frederik; Astrup, Arne.

    In: American Journal of Clinical Nutrition, Vol. 97, No. 5, 2013, p. 980-989.

    Research output: Contribution to journalJournal article

  6. Published

    Regulation of urea synthesis during the acute-phase response in rats. / Thomsen, Karen Louise; Jessen, Niels; Møller, Andreas Buch; Aagaard, Niels Kristian; Grønbæk, Henning; Holst, Jens Juul; Vilstrup, Hendrik.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 304, No. 7, 01.04.2013, p. G680-6.

    Research output: Contribution to journalJournal article

  7. Published

    Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates. / Vegge, Andreas; Thymann, Thomas; Lund, Pernille; Stoll, Barbara; Bering, Stine Brandt; Hartmann, Bolette; Jelsing, Jacob; Qvist, Niels; Burrin, Douglas G; Jeppesen, Palle Bekker; Holst, Jens Juul; Sangild, Per T.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 305, No. 4, 2013, p. G277-G285.

    Research output: Contribution to journalJournal article

  8. Published

    Islet-cell dysfunction induced by glucocorticoid treatment : potential role for altered sympathovagal balance? / van Raalte, Daniël H; Kwa, Kelly A A; van Genugten, Renate E; Tushuizen, Maarten E; Holst, Jens Juul; Deacon, Carolyn F; Karemaker, John M; Heine, Robert J; Mari, Andrea; Diamant, Michaela.

    In: Metabolism, Vol. 62, No. 4, 2013, p. 568-577.

    Research output: Contribution to journalJournal article

  9. 2012
  10. Published

    Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects : a possible link between obesity and local tissue inflammation? / Arngrim, N; Simonsen, L; Holst, Jens Juul; Bülow, J.

    In: International Journal of Obesity, Vol. 37, 2012, p. 748-50.

    Research output: Contribution to journalJournal article

  11. Published

    Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model. / Barnes, Jennifer L; Hartmann, Bolette; Holst, Jens Juul; Tappenden, Kelly A.

    In: Journal of Parenteral and Enteral Nutrition, Vol. 36, No. 5, 09.2012, p. 524-37.

    Research output: Contribution to journalJournal article

  12. Published

    Impact of postprandial glycaemia on health and prevention of disease. / Blaak, E E; Antoine, J-M; Benton, D; Björck, I; Bozzetto, L; Brouns, F; Diamant, M; Dye, L; Hulshof, T; Holst, J J; Lamport, D J; Laville, M; Lawton, C L; Meheust, A; Nilson, A; Normand, Signe; Rivellese, A A; Theis, S; Torekov, Signe Sørensen; Vinoy, S.

    In: Obesity Reviews, Vol. 13, No. 10, 2012, p. 923-984.

    Research output: Contribution to journalJournal article

  13. Published

    Enteral nutrients potentiate glucagon-like peptide-2 action and reduce dependence on parenteral nutrition in a rat model of human intestinal failure. / Brinkman, Adam S; Murali, Sangita G; Hitt, Stacy; Solverson, Patrick M; Holst, Jens Juul; Ney, Denise M.

    In: A J P: Gastrointestinal and Liver Physiology (Online), Vol. 303, No. 5, 01.09.2012, p. G610-22.

    Research output: Contribution to journalJournal article

  14. Published

    Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery. / Bryant, Eleanor J; King, Neil A; Falkén, Ylva; Hellström, Per M; Holst, Jens Juul; Blundell, John E; Näslund, Erik.

    In: Surgery for Obesity and Related Diseases, 12.10.2012.

    Research output: Contribution to journalJournal article

  15. Published

    Alcohol intake and its effect on some appetite-regulating hormones in man : influence of gastroprotection with sucralfate. / Calissendorff, Jan; Gustafsson, Thomas; Holst, Jens Juul; Brismar, Kerstin; Röjdmark, Sven.

    In: Endocrine Research, Vol. 37, No. 3, 2012, p. 154-62.

    Research output: Contribution to journalJournal article

  16. Published

    Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass. / Dirksen, C; Jørgensen, N B; Bojsen-Møller, K N; Jacobsen, S H; Hansen, D L; Worm, D; Holst, Jens Juul; Madsbad, S.

    In: Diabetologia, Vol. 55, No. 7, 2012, p. 1890-901.

    Research output: Contribution to journalJournal article

  17. Published

    A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin. / Egerod, Kristoffer L; Engelstoft, Maja S; Grunddal, Kaare V; Nøhr, Mark K; Secher, Anna; Sakata, Ichiro; Pedersen, Jens; Windeløv, Johanne A; Füchtbauer, Ernst-Martin; Olsen, Jørgen; Sundler, Frank; Christensen, Jan P; Wierup, Nils; Olsen, Jesper V; Holst, Jens J; Zigman, Jeffrey M; Poulsen, Steen S; Schwartz, Thue W.

    In: Endocrinology, Vol. 153, No. 12, 01.12.2012, p. 5782-95.

    Research output: Contribution to journalJournal article

  18. Published

    Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection. / Ekholm, E; Shaat, N; Holst, Jens Juul.

    In: Acta Diabetologica, Vol. 49, No. 5, 10.2012, p. 349-54.

    Research output: Contribution to journalJournal article

  19. Published

    Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele. / Faerch, Kristine; Pilgaard, Kasper; Knop, Filip K; Hansen, Torben; Pedersen, Oluf; Jørgensen, Torben; Holst, Jens J.

    In: Diabetes, Obesity and Metabolism Online, Vol. 15, No. 1, 2012, p. 91-95.

    Research output: Contribution to journalJournal article

  20. Published

    Adult glucose metabolism in extremely birthweight-discordant monozygotic twins. / Frost, M; Petersen, I; Brixen, K; Beck-Nielsen, Henning; Holst, Jens Juul; Christiansen, L; Højlund, Kurt; Christensen, K.

    In: Diabetologia, Vol. 55, No. 12, 12.2012, p. 3204-12.

    Research output: Contribution to journalJournal article

  21. Published

    Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia. / Gejl, Michael; Egefjord, Lærke; Lerche, Susanne; Vang, Kim; Bibby, Bo Martin; Holst, Jens Juul; Mengel, Annette; Møller, Niels; Rungby, Jørgen; Brock, Birgitte; Gjedde, Albert.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 32, No. 12, 12.2012, p. 2146-2152.

    Research output: Contribution to journalJournal article

  22. Published

    Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits. / Gjesing, Anette Marianne Prior; Ekstrøm, Claus Thorn; Eiberg, Hans Rudolf Lytchoff; Urhammer, S.A.; Holst, Jens Juul; Pedersen, Oluf; Hansen, Teis.

    In: Diabetologia, Vol. 55, No. 5, 2012, p. 1338-1345.

    Research output: Contribution to journalJournal article

  23. Published

    The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk. / Gunnerud, Ulrika; Holst, Jens Juul; Östman, Elin; Björck, Inger.

    In: Nutrition Journal, Vol. 11, 2012, p. 83.

    Research output: Contribution to journalJournal article

  24. Published

    Effects of pre-meal drinks with protein and amino acids on glycemic and metabolic responses at a subsequent composite meal. / Gunnerud, Ulrika J; Heinzle, Cornelia; Holst, Jens Juul; Östman, Elin M; Björck, Inger M E.

    In: P L o S One, Vol. 7, No. 9, 2012, p. e44731.

    Research output: Contribution to journalJournal article

  25. Published

    GPR119 as a fat sensor. / Hansen, Harald S; Rosenkilde, Mette M; Holst, Jens Juul; Schwartz, Thue W.

    In: Trends in Pharmacological Sciences, Vol. 33, No. 7, 07.2012, p. 374-81.

    Research output: Contribution to journalJournal article

  26. Published

    Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects. / Hansen, Katrine B; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 4, 2012, p. 1363-70.

    Research output: Contribution to journalJournal article

  27. Published

    Acute differential effects of milk-derived dietary proteins on postprandial lipaemia in obese non-diabetic subjects. / Holmer-Jensen, Jens; Hartvigsen, Merete; Mortensen, L.S.; Astrup, Arne; de Vrese, M.; Holst, Jens Juul; Thomsen, C.; Hermansen, K.

    In: European Journal of Clinical Nutrition, Vol. 66, 2012, p. 32-38.

    Research output: Contribution to journalJournal article

  28. Published

    Incretin based therapies : do they hold their promise? / Holst, Jens Juul.

    In: Journal of Diabetes, Vol. 4, No. 1, 2012, p. 4-7.

    Research output: Contribution to journalJournal article

  29. Published

    Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus : focus on bile acid sequestrants. / Holst, Jens Juul; McGill, Maria A.

    In: Clinical Drug Investigation, Vol. 32, No. 1, 2012, p. 1-14.

    Research output: Contribution to journalJournal article

  30. Published

    Leptin og dens betydning for vægtvedligeholdelse. / Iepsen, Eva Pers Winning; Torekov, Signe Sørensen; Holst, Jens Juul.

    In: Klinisk biokemi i Norden, Vol. 24, No. 4, 2012, p. 8-15.

    Research output: Contribution to journalJournal article

  31. Published

    Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects. / Jacobsen, S H; Olesen, S C; Dirksen, C; Jørgensen, N B; Bojsen-Møller, K N; Kielgast, U; Worm, D; Almdal, T; Naver, L S; Hvolris, L E; Rehfeld, J F; Wulff, B S; Clausen, T R; Hansen, D L; Holst, Jens Juul; Madsbad, S.

    In: Obesity Surgery, Vol. 22, No. 7, 2012, p. 1084-96.

    Research output: Contribution to journalJournal article

  32. Published

    Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs. / Jain, Ajay Kumar; Stoll, Barbara; Burrin, Douglas G; Holst, Jens Juul; Moore, David D.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 302, No. 2, 2012, p. G218-24.

    Research output: Contribution to journalJournal article

  33. Published

    Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes. / Jensen, D H; Aaboe, K; Henriksen, J E; Vølund, Anders; Holst, Jens Juul; Madsbad, S; Krarup, T.

    In: Diabetologia, Vol. 55, No. 5, 2012, p. 1406-16.

    Research output: Contribution to journalJournal article

  34. Published

    Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance. / Jørgensen, N B; Jacobsen, S H; Dirksen, C; Bojsen-Møller, K N; Naver, L; Hvolris, L; Clausen, T R; Wulff, B S; Worm, D; Lindqvist Hansen, D; Madsbad, S; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 303, No. 1, 2012, p. E122-31.

    Research output: Contribution to journalJournal article

  35. Published

    Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells. / Kappe, Camilla; Holst, Jens Juul; Zhang, Qimin; Sjöholm, Ake.

    In: Biochemical and Biophysical Research Communications, Vol. 427, No. 1, 12.10.2012, p. 91-5.

    Research output: Contribution to journalJournal article

  36. Published

    Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine. / Kissow, Hannelouise; Viby, Niels-Erik; Hartmann, Bolette; Holst, Jens Juul; Timm, Michael; Thim, Lars; Poulsen, Steen Seier.

    In: Cancer Chemotherapy and Pharmacology. Supplement, Vol. 70, No. 1, 2012, p. 39-48.

    Research output: Contribution to journalJournal article

  37. Published

    Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice. / Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul; Viby, Niels-Erik; Hansen, Lærke Schmidt; Rosenkilde, Mette Marie; Hare, Kristine Juul; Poulsen, Steen Seier.

    In: Regulatory Peptides, Vol. 179, No. 1-3, 10.11.2012, p. 91-100.

    Research output: Contribution to journalJournal article

  38. Published
  39. Published

    Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity. / Knop, Filip K; Aaboe, K; Vilsbøll, T; Vølund, Anders; Holst, Jens Juul; Krarup, T; Madsbad, S.

    In: Diabetes, Obesity and Metabolism, Vol. 14, No. 6, 2012, p. 500-510.

    Research output: Contribution to journalJournal article

  40. Published

    Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome. / Lund, Pernille; Sangild, Per Torp; Aunsholt, L.; Hartmann, Bolette; Holst, Jens Juul; Mortensen, J.; Mortensen, P.B.; Jeppesen, P.B.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 9, 2012, p. 1059-1065.

    Research output: Contribution to journalJournal article

  41. Published

    Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol. / Mandoe, M. J.; Hansen, K. B.; Knop, F. K.; Holst, J. J.; Hansen, Harald S.

    In: Diabetologia, Vol. 55, 10.2012, p. S340-S340.

    Research output: Contribution to journalConference abstract in journal

  42. Published

    Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy. / Mickiewicz, M; Zabielski, R; Grenier, B; Le Normand, L; Savary, G; Holst, Jens Juul; Oswald, I P; Metges, C C; Guilloteau, P.

    In: Journal of Physiology and Pharmacology, Vol. 63, No. 3, 2012, p. 225-39.

    Research output: Contribution to journalJournal article

  43. Published

    Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes. / Mortensen, L.S.; Holmer-Jensen, Jens; Hartvigsen, Merete; Jensen, V.K.; Astrup, Arne; Vrese, M. de; Holst, Jens Juul; Thomsen, Claus Heikki Paavo; Hermansen, Kjeld.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 7, 2012, p. 799-805.

    Research output: Contribution to journalJournal article

  44. Published

    Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes. / Muscelli, Elza; Casolaro, Arturo; Gastaldelli, Amalia; Mari, Andrea; Seghieri, Giuseppe; Astiarraga, Brenno; Chen, Yu; Alba, Maria; Holst, Jens Juul; Ferrannini, Ele.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 8, 08.2012, p. 2818-26.

    Research output: Contribution to journalJournal article

  45. Published

    Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass : the pathophysiological role of GLP1 and its response to a somatostatin analogue. / Myint, K S; Greenfield, J R; Farooqi, I S; Henning, E; Holst, Jens Juul; Finer, N.

    In: European Journal of Endocrinology, Vol. 166, No. 5, 2012, p. 951-5.

    Research output: Contribution to journalJournal article

  46. Published

    Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink : a controlled trial. / Nielsen, Maria Mærsk; Sparre, Anita Belza; Holst, Jens Juul; Fenger-Grøn, Morten; Pedersen, S.B.; Astrup, Arne; Richelsen, Bjørn.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 4, 2012, p. 523-529.

    Research output: Contribution to journalJournal article

  47. Published

    Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients. / Nielsen, R.; Wiggers, Henrik; Halbirk, Mads; Bøtker, H; Holst, Jens Juul; Schmitz, Ole; Frandsen, Egon Randa; Nielsen, S; Møller, N; Nørrelund, Helene.

    In: Experimental and Clinical Endocrinology and Diabetes, Vol. 120, No. 5, 2012, p. 266-72.

    Research output: Contribution to journalJournal article

  48. Published

    Treatment of adult short bowel syndrome patients with teduglutide. / Nørholk, Lærke Marijke; Holst, Jens Juul; Jeppesen, Palle Bekker.

    In: Expert Opinion on Pharmacotherapy, Vol. 13, No. 2, 2012, p. 235-43.

    Research output: Contribution to journalJournal article

  49. Published

    The incretin effect in patients with maturity onset diabetes of the young. / Ostoft, S. H.; Bagger, J. I.; Hansen, T.; Pedersen, O.; Holst, J. J.; Knop, F.; Vilsboll, T.

    In: Diabetologia, Vol. 55, 2012, p. S144-S144.

    Research output: Contribution to journalJournal article

  50. Published

    Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes. / Rauch, T; Graefe-Mody, U; Deacon, Carolyn F.; Ring, A; Holst, Jens Juul; Woerle, H-J; Dugi, KA; Heise, T.

    In: Diabetes Therapy, Vol. 3, No. 1, 2012, p. 10.

    Research output: Contribution to journalJournal article

  51. Published

    Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus. / Rauch, Thomas; Graefe-Mody, Ulrike; Deacon, Carolyn F; Ring, Arne; Holst, Jens Juul; Woerle, Hans-Juergen; Dugi, Klaus A; Heise, Tim.

    In: Diabetes Therapy, Vol. 3, No. 1, 11.2012, p. 10.

    Research output: Contribution to journalJournal article

  52. Published

    Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals. / Rohrer, Stefan; Menge, Björn A; Grüber, Lena; Deacon, Carolyn F; Schmidt, Wolfgang E; Veldhuis, Johannes D; Holst, Jens Juul; Meier, Juris J.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 5, 2012, p. E791-E795.

    Research output: Contribution to journalJournal article

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