Jens Juul Holst

Jens Juul Holst

Professor


  1. 2013
  2. Published

    Regulation of urea synthesis during the acute-phase response in rats. / Thomsen, Karen Louise; Jessen, Niels; Møller, Andreas Buch; Aagaard, Niels Kristian; Grønbæk, Henning; Holst, Jens Juul; Vilstrup, Hendrik.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 304, No. 7, 01.04.2013, p. G680-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates. / Vegge, Andreas; Thymann, Thomas; Lund, Pernille; Stoll, Barbara; Bering, Stine Brandt; Hartmann, Bolette; Jelsing, Jacob; Qvist, Niels; Burrin, Douglas G; Jeppesen, Palle Bekker; Holst, Jens Juul; Sangild, Per T.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 305, No. 4, 2013, p. G277-G285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Islet-cell dysfunction induced by glucocorticoid treatment : potential role for altered sympathovagal balance? / van Raalte, Daniël H; Kwa, Kelly A A; van Genugten, Renate E; Tushuizen, Maarten E; Holst, Jens Juul; Deacon, Carolyn F; Karemaker, John M; Heine, Robert J; Mari, Andrea; Diamant, Michaela.

    In: Metabolism, Vol. 62, No. 4, 2013, p. 568-577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2012
  6. Published

    Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects : a possible link between obesity and local tissue inflammation? / Arngrim, N; Simonsen, L; Holst, Jens Juul; Bülow, J.

    In: International Journal of Obesity, Vol. 37, 2012, p. 748-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model. / Barnes, Jennifer L; Hartmann, Bolette; Holst, Jens Juul; Tappenden, Kelly A.

    In: Journal of Parenteral and Enteral Nutrition, Vol. 36, No. 5, 09.2012, p. 524-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Impact of postprandial glycaemia on health and prevention of disease. / Blaak, E E; Antoine, J-M; Benton, D; Björck, I; Bozzetto, L; Brouns, F; Diamant, M; Dye, L; Hulshof, T; Holst, J J; Lamport, D J; Laville, M; Lawton, C L; Meheust, A; Nilson, A; Normand, Signe; Rivellese, A A; Theis, S; Torekov, Signe Sørensen; Vinoy, S.

    In: Obesity Reviews, Vol. 13, No. 10, 2012, p. 923-984.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Enteral nutrients potentiate glucagon-like peptide-2 action and reduce dependence on parenteral nutrition in a rat model of human intestinal failure. / Brinkman, Adam S; Murali, Sangita G; Hitt, Stacy; Solverson, Patrick M; Holst, Jens Juul; Ney, Denise M.

    In: A J P: Gastrointestinal and Liver Physiology (Online), Vol. 303, No. 5, 01.09.2012, p. G610-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery. / Bryant, Eleanor J; King, Neil A; Falkén, Ylva; Hellström, Per M; Holst, Jens Juul; Blundell, John E; Näslund, Erik.

    In: Surgery for Obesity and Related Diseases, 12.10.2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Alcohol intake and its effect on some appetite-regulating hormones in man : influence of gastroprotection with sucralfate. / Calissendorff, Jan; Gustafsson, Thomas; Holst, Jens Juul; Brismar, Kerstin; Röjdmark, Sven.

    In: Endocrine Research, Vol. 37, No. 3, 2012, p. 154-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass. / Dirksen, C; Jørgensen, N B; Bojsen-Møller, K N; Jacobsen, S H; Hansen, D L; Worm, D; Holst, Jens Juul; Madsbad, S.

    In: Diabetologia, Vol. 55, No. 7, 2012, p. 1890-901.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin. / Egerod, Kristoffer L; Engelstoft, Maja S; Grunddal, Kaare V; Nøhr, Mark K; Secher, Anna; Sakata, Ichiro; Pedersen, Jens; Windeløv, Johanne A; Füchtbauer, Ernst-Martin; Olsen, Jørgen; Sundler, Frank; Christensen, Jan P; Wierup, Nils; Olsen, Jesper V; Holst, Jens J; Zigman, Jeffrey M; Poulsen, Steen S; Schwartz, Thue W.

    In: Endocrinology, Vol. 153, No. 12, 01.12.2012, p. 5782-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection. / Ekholm, E; Shaat, N; Holst, Jens Juul.

    In: Acta Diabetologica, Vol. 49, No. 5, 10.2012, p. 349-54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele. / Faerch, Kristine; Pilgaard, Kasper; Knop, Filip K; Hansen, Torben; Pedersen, Oluf; Jørgensen, Torben; Holst, Jens J.

    In: Diabetes, Obesity and Metabolism Online, Vol. 15, No. 1, 2012, p. 91-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Adult glucose metabolism in extremely birthweight-discordant monozygotic twins. / Frost, M; Petersen, I; Brixen, K; Beck-Nielsen, Henning; Holst, Jens Juul; Christiansen, L; Højlund, Kurt; Christensen, K.

    In: Diabetologia, Vol. 55, No. 12, 12.2012, p. 3204-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia. / Gejl, Michael; Egefjord, Lærke; Lerche, Susanne; Vang, Kim; Bibby, Bo Martin; Holst, Jens Juul; Mengel, Annette; Møller, Niels; Rungby, Jørgen; Brock, Birgitte; Gjedde, Albert.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 32, No. 12, 12.2012, p. 2146-2152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits. / Gjesing, Anette Marianne Prior; Ekstrøm, Claus Thorn; Eiberg, Hans Rudolf Lytchoff; Urhammer, S.A.; Holst, Jens Juul; Pedersen, Oluf; Hansen, Teis.

    In: Diabetologia, Vol. 55, No. 5, 2012, p. 1338-1345.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk. / Gunnerud, Ulrika; Holst, Jens Juul; Östman, Elin; Björck, Inger.

    In: Nutrition Journal, Vol. 11, 2012, p. 83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effects of pre-meal drinks with protein and amino acids on glycemic and metabolic responses at a subsequent composite meal. / Gunnerud, Ulrika J; Heinzle, Cornelia; Holst, Jens Juul; Östman, Elin M; Björck, Inger M E.

    In: P L o S One, Vol. 7, No. 9, 2012, p. e44731.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    GPR119 as a fat sensor. / Hansen, Harald S; Rosenkilde, Mette M; Holst, Jens Juul; Schwartz, Thue W.

    In: Trends in Pharmacological Sciences, Vol. 33, No. 7, 07.2012, p. 374-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects. / Hansen, Katrine B; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 4, 2012, p. 1363-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Acute differential effects of milk-derived dietary proteins on postprandial lipaemia in obese non-diabetic subjects. / Holmer-Jensen, Jens; Hartvigsen, Merete; Mortensen, L.S.; Astrup, Arne; de Vrese, M.; Holst, Jens Juul; Thomsen, C.; Hermansen, K.

    In: European Journal of Clinical Nutrition, Vol. 66, 2012, p. 32-38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Incretin based therapies : do they hold their promise? / Holst, Jens Juul.

    In: Journal of Diabetes, Vol. 4, No. 1, 2012, p. 4-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus : focus on bile acid sequestrants. / Holst, Jens Juul; McGill, Maria A.

    In: Clinical Drug Investigation, Vol. 32, No. 1, 2012, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Leptin og dens betydning for vægtvedligeholdelse. / Iepsen, Eva Pers Winning; Torekov, Signe Sørensen; Holst, Jens Juul.

    In: Klinisk biokemi i Norden, Vol. 24, No. 4, 2012, p. 8-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects. / Jacobsen, S H; Olesen, S C; Dirksen, C; Jørgensen, N B; Bojsen-Møller, K N; Kielgast, U; Worm, D; Almdal, T; Naver, L S; Hvolris, L E; Rehfeld, J F; Wulff, B S; Clausen, T R; Hansen, D L; Holst, Jens Juul; Madsbad, S.

    In: Obesity Surgery, Vol. 22, No. 7, 2012, p. 1084-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs. / Jain, Ajay Kumar; Stoll, Barbara; Burrin, Douglas G; Holst, Jens Juul; Moore, David D.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 302, No. 2, 2012, p. G218-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes. / Jensen, D H; Aaboe, K; Henriksen, J E; Vølund, Anders; Holst, Jens Juul; Madsbad, S; Krarup, T.

    In: Diabetologia, Vol. 55, No. 5, 2012, p. 1406-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance. / Jørgensen, N B; Jacobsen, S H; Dirksen, C; Bojsen-Møller, K N; Naver, L; Hvolris, L; Clausen, T R; Wulff, B S; Worm, D; Lindqvist Hansen, D; Madsbad, S; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 303, No. 1, 2012, p. E122-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells. / Kappe, Camilla; Holst, Jens Juul; Zhang, Qimin; Sjöholm, Ake.

    In: Biochemical and Biophysical Research Communications, Vol. 427, No. 1, 12.10.2012, p. 91-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine. / Kissow, Hannelouise; Viby, Niels-Erik; Hartmann, Bolette; Holst, Jens Juul; Timm, Michael; Thim, Lars; Poulsen, Steen Seier.

    In: Cancer Chemotherapy and Pharmacology. Supplement, Vol. 70, No. 1, 2012, p. 39-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice. / Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul; Viby, Niels-Erik; Hansen, Lærke Schmidt; Rosenkilde, Mette Marie; Hare, Kristine Juul; Poulsen, Steen Seier.

    In: Regulatory Peptides, Vol. 179, No. 1-3, 10.11.2012, p. 91-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Glucagon-like peptide-1 as a treatment for chemotherapy-induced mucositis. / Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul; Poulsen, Steen Seier.

    In: Gut, 20.10.2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity. / Knop, Filip K; Aaboe, K; Vilsbøll, T; Vølund, Anders; Holst, Jens Juul; Krarup, T; Madsbad, S.

    In: Diabetes, Obesity and Metabolism, Vol. 14, No. 6, 2012, p. 500-510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome. / Lund, Pernille; Sangild, Per Torp; Aunsholt, L.; Hartmann, Bolette; Holst, Jens Juul; Mortensen, J.; Mortensen, P.B.; Jeppesen, P.B.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 9, 2012, p. 1059-1065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol. / Mandoe, M. J.; Hansen, K. B.; Knop, F. K.; Holst, J. J.; Hansen, Harald S.

    In: Diabetologia, Vol. 55, 10.2012, p. S340-S340.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  38. Published

    Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy. / Mickiewicz, M; Zabielski, R; Grenier, B; Le Normand, L; Savary, G; Holst, Jens Juul; Oswald, I P; Metges, C C; Guilloteau, P.

    In: Journal of Physiology and Pharmacology, Vol. 63, No. 3, 2012, p. 225-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes. / Mortensen, L.S.; Holmer-Jensen, Jens; Hartvigsen, Merete; Jensen, V.K.; Astrup, Arne; Vrese, M. de; Holst, Jens Juul; Thomsen, Claus Heikki Paavo; Hermansen, Kjeld.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 7, 2012, p. 799-805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes. / Muscelli, Elza; Casolaro, Arturo; Gastaldelli, Amalia; Mari, Andrea; Seghieri, Giuseppe; Astiarraga, Brenno; Chen, Yu; Alba, Maria; Holst, Jens Juul; Ferrannini, Ele.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 8, 08.2012, p. 2818-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass : the pathophysiological role of GLP1 and its response to a somatostatin analogue. / Myint, K S; Greenfield, J R; Farooqi, I S; Henning, E; Holst, Jens Juul; Finer, N.

    In: European Journal of Endocrinology, Vol. 166, No. 5, 2012, p. 951-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink : a controlled trial. / Nielsen, Maria Mærsk; Sparre, Anita Belza; Holst, Jens Juul; Fenger-Grøn, Morten; Pedersen, S.B.; Astrup, Arne; Richelsen, Bjørn.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 4, 2012, p. 523-529.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients. / Nielsen, R.; Wiggers, Henrik; Halbirk, Mads; Bøtker, H; Holst, Jens Juul; Schmitz, Ole; Frandsen, Egon Randa; Nielsen, S; Møller, N; Nørrelund, Helene.

    In: Experimental and Clinical Endocrinology and Diabetes, Vol. 120, No. 5, 2012, p. 266-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Treatment of adult short bowel syndrome patients with teduglutide. / Nørholk, Lærke Marijke; Holst, Jens Juul; Jeppesen, Palle Bekker.

    In: Expert Opinion on Pharmacotherapy, Vol. 13, No. 2, 2012, p. 235-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The incretin effect in patients with maturity onset diabetes of the young. / Ostoft, S. H.; Bagger, J. I.; Hansen, T.; Pedersen, O.; Holst, J. J.; Knop, F.; Vilsboll, T.

    In: Diabetologia, Vol. 55, 2012, p. S144-S144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes. / Rauch, T; Graefe-Mody, U; Deacon, Carolyn F.; Ring, A; Holst, Jens Juul; Woerle, H-J; Dugi, KA; Heise, T.

    In: Diabetes Therapy, Vol. 3, No. 1, 2012, p. 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus. / Rauch, Thomas; Graefe-Mody, Ulrike; Deacon, Carolyn F; Ring, Arne; Holst, Jens Juul; Woerle, Hans-Juergen; Dugi, Klaus A; Heise, Tim.

    In: Diabetes Therapy, Vol. 3, No. 1, 11.2012, p. 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals. / Rohrer, Stefan; Menge, Björn A; Grüber, Lena; Deacon, Carolyn F; Schmidt, Wolfgang E; Veldhuis, Johannes D; Holst, Jens Juul; Meier, Juris J.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 5, 2012, p. E791-E795.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells. / Salehi, Albert; Gunnerud, Ulrika; Muhammed, Sarheed J; Ostman, Elin; Holst, Jens Juul; Björck, Inger; Rorsman, Patrik.

    In: Nutrition & Metabolism, Vol. 9, No. 1, 2012, p. 48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Effects of intravenous infusions of PYY3-36 and GLP-1, as monoinfusion and in combination, on ad libitum energy intake in healthy obese subjects. / Schmidt, Julie Berg; Gregersen, Nikolaj Ture; Pedersen, Susie Dawn; Holst, Jens Juul; Schwartz, Thue W.; Astrup, Arne; Sjödin, Anders Mikael.

    In: Regulatory Peptides, Vol. 177, No. Supplement, 10.08.2012, p. S32.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  51. Published

    Roux-en-Y gastric bypass surgery does not preserve energy expenditure in humans. / Schmidt, Julie Berg; Gunvald, Luise Enggaard; Gregersen, Nikolaj Ture; Pedersen, Susie Dawn; Holst, Jens Juul; Hansen, Dorte Lindqvist; Worm, Dorte; Madsbad, Sten; Astrup, Arne; Sjödin, Anders Mikael.

    In: Regulatory Peptides, Vol. 177, No. suppl.1, 2012, p. S32.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  52. Published

    Effects of everyday life events on glucose, insulin, and glucagon dynamics in continuous subcutaneous insulin infusion-treated type 1 diabetes : collection of clinical data for glucose modeling. / Schmidt, Signe Damkjær; Finan, Daniel Aaron; Duun-Henriksen, Anne Katrine; Jørgensen, John Bagterp; Madsen, Henrik; Bengtsson, Henrik; Holst, Jens Juul; Madsbad, Sten; Nørgaard, Kirsten.

    In: Diabetes Technology & Therapeutics, Vol. 14, No. 3, 2012, p. 210-217.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model. / Shang, Quan; Liu, Matthew K; Saumoy, Monica; Holst, Jens Juul; Salen, Gerald; Xu, Guorong.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 302, No. 8, 2012, p. G815-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The effect of glucagon-like peptide 1 on cardiovascular risk. / Sivertsen, Jacob; Rosenmeier, Jaya; Holst, Jens Juul; Vilsbøll, Tina.

    In: Nature Reviews Cardiology, Vol. 9, No. 4, 04.2012, p. 209-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Examining the effects of hyperglycemia on pancreatic endocrine function in humans : evidence for in vivo glucotoxicity. / Solomon, Thomas P J; Knudsen, Sine H; Karstoft, Kristian; Winding, Kamilla; Holst, Jens Juul; Pedersen, Bente K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 12, 12.2012, p. 4682-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs. / Stoll, Barbara; Puiman, Patrycja Jolanta; Cui, Liwei; Chang, Xiaoyan; Benight, Nancy Marie; Bauchart-Thevret, Caroline; Hartmann, Bolette; Holst, Jens Juul; Burrin, Douglas Guy.

    In: Journal of Parenteral and Enteral Nutrition, Vol. 36, No. 5, 09.2012, p. 538-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women. / Svendsen, Pernille F; Jensen, Frank K; Holst, Jens Juul; Haugaard, Steen B; Nilas, Lisbeth; Madsbad, Sten.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 72, No. 5, 09.2012, p. 410-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves. / Taylor-Edwards, C C; Burrin, D G; Kristensen, N B; Holst, Jens Juul; McLeod, K R; Harmon, D L.

    In: Animal, Vol. 6, No. 12, 12.2012, p. 1985-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus). / Verbrugghe, A; Hesta, M; Daminet, S; Polis, I; Holst, Jens Juul; Buyse, J; Wuyts, B; Janssens, G P J.

    In: Journal of Animal Physiology and Animal Nutrition (Online), Vol. 96, No. 6, 12.2012, p. 1054-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets. / van der Meer, Y; Gerrits, W J J; van den Bosch, M; Holst, Jens Juul; Moreto, M; Buurman, W A; Kulik, W; van Kempen, T A T G.

    In: Journal of Animal Science, Vol. 90 Suppl 4, 12.2012, p. 302-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 2011
  62. Published

    Glucagon antagonism as a potential therapeutic target in type 2 diabetes. / Bagger, J I; Knop, F K; Holst, Jens Juul; Vilsbøll, T.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 11, 11.2011, p. 965-971.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Impaired regulation of the incretin effect in patients with type 2 diabetes. / Bagger, Jonatan I; Knop, Filip K; Lund, Asger; Vestergaard, Henrik; Holst, Jens Juul; Vilsbøll, Tina.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 3, 2011, p. 737-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients. / Bremholm, Lasse; Hornum, Mads; Andersen, Ulrik B; Hartmann, Bolette; Holst, Jens Juul; Jeppesen, Palle Bekker.

    In: Regulatory Peptides, Vol. 168, No. 1-3, 2011, p. 32-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin : a double-blinded randomized cross-over study. / Brock Jacobsen, I; Vind, B F; Korsholm, Lars; Flyvbjerg, A; Frystyk, Jan; Holst, Jens Juul; Beck-Nielsen, Henning; Henriksen, J E.

    In: Acta Physiologica (Print), Vol. 202, No. 3, 2011, p. 337-347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events : Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials. / Buse, John B; Garber, Alan; Rosenstock, Julio; Schmidt, Wolfgang E; Brett, Jason H; Videbæk, Nicoline; Holst, Jens Juul; Nauck, Michael.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 6, 2011, p. 1695-702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Glucose-dependent insulinotropic polypeptide : a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans. / Christensen, Mikkel; Vedtofte, Louise; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip K.

    In: Diabetes, Vol. 60, No. 12, 2011, p. 3103-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Lixisenatide for type 2 diabetes mellitus. / Christensen, Mikkel; Knop, Filip K; Vilsbøll, Tina; Holst, Jens Juul.

    In: Expert Opinion on Investigational Drugs, Vol. 20, No. 4, 2011, p. 549-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery : Role of Gut Peptides. / Falkén, Y; Hellström, P M; Holst, Jens Juul; Näslund, E.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 7, 2011, p. 2227-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published
  71. Published

    The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status. / Gjesing, Anette P; Vestmar, Marie A; Jørgensen, Torben; Heni, Martin; Holst, Jens J; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf.

    In: P L o S One, Vol. 6, No. 9, 01.01.2011, p. e23907.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Effect of method of delivery of sodium butyrate on rumen development in newborn calves. / Górka, P; Kowalski, Z M; Pietrzak, P; Kotunia, A; Jagusiak, W; Holst, Jens Juul; Guilloteau, P; Zabielski, R.

    In: Journal of Dairy Science, Vol. 94, No. 11, 11.2011, p. 5578-88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia? / Hansen, A M K; Bödvarsdottir, T B; Nordestgaard, D N E; Heller, R S; Gotfredsen, C F; Maedler, K; Fels, JJ; Holst, Jens Juul; Karlsen, AE.

    In: Diabetologia, Vol. 54, No. 6, 2011, p. 1379-87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. / Hansen, Katrine B; Rosenkilde, Mette M; Knop, Filip K; Wellner, Niels; Diep, Thi A; Rehfeld, Jens F; Andersen, Ulrik B; Holst, Jens J; Hansen, Harald S.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 9, 2011, p. E1409-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects. / Hansen, Katrine B; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 2, 2011, p. 447-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4. / Hansen, Morten; Knop, Filip Krag; Holst, Jens Juul.

    In: Medecine des Maladies Metaboliques, Vol. 5, No. 2, 04.2011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors. / Hansen, Morten; Juul Hare, Kristine; Holst, Jens Juul; Knop, Filip Krag.

    In: Journal of Clinical Metabolism & Diabetes, Vol. 2, No. 2, 06.2011, p. 7-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes. / Henry, R R; Smith, Susanne; Schwartz, Saul; Mudaliar, S R; Deacon, C F; Holst, Jens Juul; Duan, R Y; Chen, R S; List, J F.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 9, 2011, p. 850-858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Delayed ß-cell response and glucose intolerance in young women with Turner syndrome. / Hjerrild, Britta Eilersen; Holst, Jens Juul; Juhl, Claus; Christiansen, Jens Sandahl; Schmitz, Ole; Gravholt, Claus Højbjerg.

    In: B M C Endocrine Disorders, Vol. 11, 2011, p. 11-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs. / Hjøllund, K R; Deacon, C F; Holst, Jens Juul.

    In: Diabetologia, Vol. 54, No. 8, 2011, p. 2206-8.

    Research output: Contribution to journalLetterResearchpeer-review

  81. Published

    Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes. / Holst, Jens Juul; Knop, Filip K; Vilsbøll, Tina; Krarup, Thure; Madsbad, Sten.

    In: Diabetes Care, Vol. 34, No. Supplement 2, 05.2011, p. S251-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Neuroprotective properties of GLP-1 : theoretical and practical applications. / Holst, Jens Juul; Burcelin, Remy; Nathanson, Esther.

    In: Current Medical Research and Opinion, Vol. 27, No. 3, 2011, p. 547-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Postprandial insulin secretion after gastric bypass surgery : the role of glucagon-like peptide 1. / Holst, Jens Juul.

    In: Diabetes, Vol. 60, No. 9, 09.2011, p. 2203-2205.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Regulation of glucagon secretion by incretins. / Holst, Jens Juul; Christensen, M; Lund, A; de Heer, J; Svendsen, B; Kielgast, U; Knop, F K.

    In: Diabetes, Obesity and Metabolism, Vol. 13 , No. Suppl 1, 10.2011, p. 89-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Foetal proglucagon processing in relation to adult appetite control : lessons from a transplantable rat glucagonoma with severe anorexia. / Jensen, P B; Larsen, P J; Karlsen, C; Jensen, H I; Holst, Jens Juul; Madsen, O D.

    In: Diabetes, Obesity and Metabolism, Vol. 13 , No. Suppl. 1, 10.2011, p. 60-68.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Gastric bypass and duodenal and gastric feeding : a comment to Hansen et al. / Jorgensen, N B; Dirksen, C; Holst, Jens Juul; Madsbad, S.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 301, No. 5, 2011, p. G938-G9389.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes. / Ketterer, Caroline; Müssig, Karsten; Heni, Martin; Dudziak, Katarzyna; Randrianarisoa, Elko; Wagner, Robert; Machicao, Fausto; Stefan, Norbert; Holst, Jens Juul; Fritsche, Andreas; Häring, Hans-Ulrich; Staiger, Harald.

    In: Metabolism, Vol. 60, No. 9, 2011, p. 1325-1333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function. / Kielgast, Urd; Holst, Jens Juul; Madsbad, Sten.

    In: Diabetes, Vol. 60, No. 5, 05.2011, p. 1599-1607.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function. / Kielgast, Urd; Krarup, Thure; Holst, Jens Juul; Madsbad, Sten; Krarup, Thure.

    In: Diabetes Care, Vol. 34, No. 7, 07.2011, p. 1463-1468.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women. / Krog-Mikkelsen, Inger; Sloth, Birgitte; Dimitrov, Dimiter; Tetens, Inge; Björck, Inger; Flint, Anne; Holst, Jens Juul; Astrup, Arne; Elmstähl, Helena; Raben, Anne Birgitte.

    In: Journal of Nutrition, Vol. 141, No. 9, 2011, p. 1679-1684.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    The effects of L-arabinose on intestinal sucrase activity : dose-response studies in vitro and in humans. / Krog-Mikkelsen, Inger; Hels, Ole; Tetens, Inge; Holst, Jens Juul; Andersen, Jens Rikardt; Bukhave, Klaus.

    In: American Journal of Clinical Nutrition, Vol. 94, No. 2, 2011, p. 472-478.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Dissociated incretin hormone response to protein versus fat ingestion in obese subjects. / Lindgren, O; Carr, RD; Holst, Jens Juul; Deacon, Carolyn F.; Ahren, B.

    In: Diabetes, Obesity and Metabolism Online, Vol. 13, No. 9, 07.2011, p. 863-865.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans. / Lindgren, Ola; Carr, Richard D; Deacon, Carolyn F; Holst, Jens Juul; Pacini, Giovanni; Mari, Andrea; Ahrén, Bo.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 8, 08.2011, p. 2519-2524.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes. / Lund, Asger; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 300, No. 6, 2011, p. E1038-E1046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction. / Lønborg, Jacob; Vejlstrup, Niels; Kelbæk, Henning; Bøtker, Hans Erik; Kim, Won Yong; Mathiasen, Anders B; Jørgensen, Erik; Helqvist, Steffen; Saunamäki, Kari; Clemmensen, Peter; Holmvang, Lene; Thuesen, Leif; Krusell, Lars Romer; Jensen, Jan S; Køber, Lars; Treiman, Marek; Holst, Jens Juul; Engstrøm, Thomas.

    In: European Heart Journal, Vol. 33, No. 12, 2011, p. 1491-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future. / Madsbad, S; Kielgast, U; Asmar, M; Deacon, C F; Torekov, Signe Sørensen; Holst, J J.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 5, 05.2011, p. 394-407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes. / Menge, Björn A; Grüber, Lena; Jørgensen, Signe M; Deacon, Carolyn F; Schmidt, Wolfgang E; Veldhuis, Johannes D; Holst, Jens Juul; Meier, Juris J.

    In: Diabetes, Vol. 60, No. 8, 08.2011, p. 2160-2168.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes. / Mentis, Nikolaos; Vardarli, Irfan; Köthe, Lars D; Holst, Jens Juul; Deacon, Carolyn F; Theodorakis, Michael; Meier, Juris J; Nauck, Michael A.

    In: Diabetes, Vol. 60, No. 4, 2011, p. 1270-1276.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test. / Møller, Jonas B; Jusko, William J; Gao, Wei; Hansen, Torben; Pedersen, Oluf; Holst, Jens J; Overgaard, Rune Viig; Madsen, Henrik; Ingwersen, Steen H.

    In: Journal of Pharmacokinetics and Pharmacodynamics, Vol. 38, No. 6, 2011, p. 713-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal. / Naessén, Sabine; Carlström, Kjell; Holst, Jens Juul; Hellström, Per M; Hirschberg, Angelica L.

    In: American Journal of Clinical Nutrition, Vol. 94, No. 4, 2011, p. 967-972.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men. / Nathanson, D; Zethelius, B; Berne, C; Lind, L; Andrén, B; Ingelsson, E; Holst, Jens Juul; Nyström, T.

    In: Diabetic Medicine, Vol. 28, No. 3, 03.2011, p. 301-305.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes : what is up, what is down? / Nauck, M A; Vardarli, I; Deacon, C F; Holst, Jens Juul; Meier, Joachim.

    In: Diabetologia, Vol. 54, No. 1, 2011, p. 10-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans. / Nauck, Michael A; Kemmeries, Guido; Holst, Jens Juul; Meier, Juris J.

    In: Diabetes, Vol. 60, No. 5, 2011, p. 1561-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

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