Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor


  1. Published

    Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone : effects of hydrogen bonding and α-chirality in the β-peptoid residues. / Jing, Xiaona; Yang, Mingjun; Kasimova, Marina Robertovna; Malmsten, Martin; Franzyk, Henrik; Jørgensen, Lene; Foged, Camilla; Nielsen, Hanne Mørck.

    In: BBA General Subjects, Vol. 1818, No. 11, 2012, p. 2660-2668.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Metabolic cleavage and translocation efficiency of selected cell penetrating peptides : A comparative study with epithelial cell cultures. / Foerg, Christina; Weller, Kathrin M.; Rechsteiner, Helene; Nielsen, Hanne Mørck; Fernandez-Carneado, Jimena; Brunisholz, Rene; Giralt, Ernest; Merkle, Hans P.

    In: The AAPS Journal, Vol. 10, No. 2, 2008, p. 349-359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Metabolic cleavage and translocation efficiency of selected cell penetrating peptides : A comparative study with epithelial cell cultures. / Foerg, Christina; Weller, Kathrin M.; Rechsteiner, Helene; Nielsen, Hanne Mørck; Fernandez-Carneado, Jimena; Brunisholz, Rene; Giralt, Ernest; Merkle, Hans P.

    In: The AAPS Journal, Vol. 10, No. 2, 2008, p. 349-359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Metabolic cleavage of cell-penetrating peptides in contact with epithelial models : human calcitonin (hCT)-derived peptides, Tat(47-57) and penetratin(43-58). / Tréhin, Rachel; Nielsen, Hanne Mørck; Jahnke, Heinz-Georg; Krauss, Ulrike; Beck-Sickinger, Annette G.; Merkle, Hans P.

    In: Biochemical Journal, Vol. 382, No. Pt 3, 2004, p. 945-56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptidomimetics and lipid bilayers. / Nielsen, Hanne Mørck; Jing, Xiaona; Simonsen, A.; Kasimova, Marina Robertovna; Malmsten, M.; Franzyk, Henrik; Foged, Camilla.

    In: Journal of Peptide Science, Vol. 16, No. s1, 2010, p. 151.

    Research output: Contribution to journalConference abstract in journalResearch

  6. Published

    Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptidomimetics and lipid bilayers. / Nielsen, Hanne Mørck; Jing, Xiaona; Simonsen, A.; Kasimova, Marina Robertovna; Malmsten, M.; Franzyk, Henrik; Foged, Camilla.

    In: Journal of Peptide Science, Vol. 16, No. s1, 2010, p. 151.

    Research output: Contribution to journalConference abstract in journalResearch

  7. Published

    Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group. / Jing, Xiaona; Simonsen, Anders Husted; Kasimova, Marina Robertovna; Franzyk, Henrik; Foged, Camilla; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23/24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  8. Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group. / Jing, Xiaona; Simonsen, Anders Husted; Kasimova, Marina Robertovna; Franzyk, Henrik; Foged, Camilla; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23/24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  9. Published

    Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement. / Rune Jørgensen, Jacob; Leth Jepsen, Morten; Hagner Nielsen, Line; Dufva, Martin; Mørck Nielsen, Hanne; Rades, Thomas; Boisen, Anja; Müllertz, Anette.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 143, 2019, p. 98-105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Modulation of the adjuvant activity of DDA/TDB liposomes with immunostimulators. / Nordly, Pernille Juul; Foged, Camilla; Christensen, D.; Lindenstrøm, T.; Nielsen, Hanne Mørck; Agger, E.

    2010. Poster session presented at  36th Annual Meeting & Exposition of the controlled release society - Innovation in discovery, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  11. Published

    Modulation of the adjuvant activity of DDA/TDB liposomes with immunostimulators. / Nordly, Pernille Juul; Foged, Camilla; Christensen, D.; Lindenstrøm, T.; Nielsen, Hanne Mørck; Agger, E.

    2010. Poster session presented at  36th Annual Meeting & Exposition of the controlled release society - Innovation in discovery, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  12. Published

    Molecular Characterization of the Interaction between siRNA and PAMAM G7 Dendrimers by SAXS, ITC, and Molecular Dynamics Simulations. / Jensen, Linda B.; Mortensen, Kell; Pavan, Giovanni M.; Kasimova, Marina R.; Jensen, Ditte K.; Gadzhyeva, Veronika; Nielsen, Hanne M.; Foged, Camilla.

    In: Biomacromolecules, Vol. 11, No. 12, 12.2010, p. 3571-3577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simultations. / Jensen, Linda Boye; Mortensen, Kell; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Jensen, Ditte K.; Gadzhyeva, Veronika; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Biomacromolecules, Vol. 11, No. 12, 2010, p. 3571-3577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simultations. / Jensen, Linda Boye; Mortensen, Kell; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Jensen, Ditte K.; Gadzhyeva, Veronika; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Biomacromolecules, Vol. 11, No. 12, 2010, p. 3571-3577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Mucosal drug delivery : barriers, in vitro models and formulation strategies. / Bøgh, Marie; Foged, Camilla; Müllertz, Anette; Nielsen, Hanne Mørck.

    In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 2013, p. 383-391.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Mucosal drug delivery : barriers, in vitro models and formulation strategies. / Bøgh, Marie; Foged, Camilla; Müllertz, Anette; Nielsen, Hanne Mørck.

    In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 2013, p. 383-391.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Mucus as a Barrier to Drug Delivery : Understanding and Mimicking the Barrier Properties. / Bøgh, Marie; Nielsen, Hanne Mørck.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 116, No. 3, 03.2015, p. 179-186.

    Research output: Contribution to journalReviewResearchpeer-review

  18. NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01. / Christensen, Dennis; Allesø, Morten; Rosenkrands, Ida; Rantanen, Jukka Tapio; Foged, Camilla; Agger, Else Marie; Andersen, Peter; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 70, No. 3, 2008, p. 914-920.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01. / Christensen, Dennis; Allesø, Morten; Rosenkrands, Ida; Rantanen, Jukka Tapio; Foged, Camilla; Agger, Else Marie; Andersen, Peter; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 70, No. 3, 2008, p. 914-920.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA. / Foged, Camilla (Inventor); Franzyk, Henrik (Inventor); Zeng, Xianghui (Inventor); Nielsen, Hanne Mørck (Inventor); Thanki, Kaushik (Inventor).

    IPC No.: A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00. Patent No.: WO2017158093-A1. Mar 16, 2017.

    Research output: PatentResearch

  21. Published

    Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells. / Water, Jorrit Jeroen; Smart, Simon; Franzyk, Henrik; Foged, Camilla; Nielsen, Hanne Mørck.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 92, 18.02.2015, p. 65-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Nicotine permeability across the buccal TR146 cell culture model and porcine buccal mucosa in vitro : effect of pH and concentration. / Nielsen, Hanne Mørck; Rassing, Margrethe Rømer.

    In: European Journal of Pharmaceutical Sciences, Vol. 16, No. 3, 2002, p. 151-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Novel Silicone Composite for Prolonged Release of Antimicrobial Peptides. / Steffensen, Søren Langer; Møller, Eva Horn; Franzyk, Henrik; Jensen, Minna Grønning; Alm, Martin; Nielsen, Hanne Mørck.

    2013. Poster session presented at Controlled Release Society Meeting 2013, Honolulu, United States.

    Research output: Contribution to conferencePosterResearchpeer-review

  24. Novel Silicone Composite for Prolonged Release of Antimicrobial Peptides. / Steffensen, Søren Langer; Møller, Eva Horn; Franzyk, Henrik; Jensen, Minna Grønning; Alm, Martin; Nielsen, Hanne Mørck.

    2013. Poster session presented at Controlled Release Society Meeting 2013, Honolulu, United States.

    Research output: Contribution to conferencePosterResearchpeer-review

  25. Published

    On the temperature dependence of complex formation between chitosan and proteins. / Kasimova, Marina Robertovna; Valázquez-Campoy, Adrián ; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 12, No. 7, 2011, p. 2534-2543.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. On the temperature dependence of complex formation between chitosan and proteins. / Kasimova, Marina Robertovna; Valázquez-Campoy, Adrián; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 12, No. 7, 2011, p. 2534-2543.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Oral delivery of peptides and proteins using lipid-based drug delivery systems. / Li, Ping; Nielsen, Hanne Mørck; Müllertz, Anette.

    In: Expert Opinion on Drug Delivery, Vol. 9, No. 10, 2012, p. 1289-304.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Parathyroid hormone coupled to cell-penetrating peptides for oral delivery. / Kristensen, Mie; Nielsen, Hanne Mørck.

    2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  29. Published

    Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation. / Kristensen, Mie; Franzyk, Henrik; Klausen, M. T. ; Iversen, A; Bahnsen, Jesper Søborg; Skyggebjerg, R. B.; Foderà, Vito; Nielsen, Hanne Mørck.

    In: A A P S Journal, Vol. 17, No. 5, 2015, p. 1200-1209.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation. / Kristensen, Mie; Franzyk, Henrik; Klausen, M. T.; Iversen, A; Bahnsen, Jesper Søborg; Skyggebjerg, R. B.; Foderà, Vito; Nielsen, Hanne Mørck.

    In: A A P S Journal, Vol. 17, No. 5, 2015, p. 1200-1209.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Penetratin-mediated transepithelial insulin pemeation: Importance of complexation? / Kristensen, Mie; Foderà, Vito; Nielsen, Hanne Mørck.

    2015.

    Research output: Contribution to conferencePosterResearchpeer-review

  32. Published

    Peptide-enhanced oral delivery of therapeutic peptides and proteins. / Kristensen, Mie; Foged, Camilla; Berthelsen, Jens; Nielsen, Hanne Mørck.

    In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 2013, p. 365-373.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Peptide-enhanced oral delivery of therapeutic peptides and proteins. / Kristensen, Mie; Foged, Camilla; Berthelsen, Jens; Nielsen, Hanne Mørck.

    In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 2013, p. 365-373.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa. / Greco, Ines; Damborg, Peter Panduro; Guardabassi, Luca; Nielsen, Hanne Mørck; Hansen, Paul Robert.

    2013. Poster session presented at ULLA Summerschool, London, United Kingdom.

    Research output: Contribution to conferencePosterResearchpeer-review

  35. Published

    Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa. / Greco, Ines; Damborg, Peter Panduro; Guardabassi, Luca; Nielsen, Hanne Mørck; Hansen, Paul Robert.

    2013. Poster session presented at ULLA Summerschool, London, United Kingdom.

    Research output: Contribution to conferencePosterResearchpeer-review

  36. Published

    Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA). / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Journal of Liposome Research, Vol. 17, No. 3-4, 2007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA). / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Journal of Liposome Research, Vol. 17, No. 3-4, 2007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Poly(ethylene carbonate)-containing polylactic acid microparticles with rifampicin improve drug delivery to macrophages. / Priemel, Petra A.; Wang, Yingya; Bohr, Adam; Water, Jorrit J.; Yang, Mingshi; Nielsen, Hanne Morck.

    In: Journal of Pharmacy and Pharmacology, Vol. 70, No. 8, 08.2018, p. 1009-1021.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Polymeric nanocarriers for siRNA delivery : challenges and future prospects. / Cun, Dongmei; Jensen, Linda Boye; Nielsen, Hanne Mørck; Moghimi, Seyed Moien; Foged, Camilla.

    In: Journal of Biomedical Nanotechnology, Vol. 4, No. 3, 2008, p. 258-275.

    Research output: Contribution to journalReviewResearch

  40. Polymeric nanocarriers for siRNA delivery : challenges and future prospects. / Cun, Dongmei; Jensen, Linda Boye; Nielsen, Hanne Mørck; Moghimi, Seyed Moien; Foged, Camilla.

    In: Journal of Biomedical Nanotechnology, Vol. 4, No. 3, 2008, p. 258-275.

    Research output: Contribution to journalReviewResearch

  41. Published

    Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems. / Li, Ping; Nielsen, Hanne Mørck; Fano, Mathias; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 102, No. 8, 08.2013, p. 2689-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery. / Cun, Dongmei; Foged, Camilla; Yang, Mingshi; Frøkjær, Sven; Nielsen, Hanne Mørck.

    In: Internation Journal of Pharmaceutics, Vol. 390, No. 1, 2010, p. 70-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery. / Cun, Dongmei; Foged, Camilla; Yang, Mingshi; Frøkjær, Sven; Nielsen, Hanne Mørck.

    In: Internation Journal of Pharmaceutics, Vol. 390, No. 1, 2010, p. 70-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption. / Bøgh, Marie; Baldursdóttir, Stefania G; Müllertz, Anette; Nielsen, Hanne M.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 87, 08.01.2014, p. 227-235.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Qualitative and quantitative analysis of the biophysical interaction of inhaled nanoparticles with pulmonary surfactant by using quartz crystal microbalance with dissipation monitoring. / Wan, Feng; Nylander, Tommy; Foged, Camilla; Yang, Mingshi; Baldursdottir, Stefania G; Nielsen, Hanne M.

    In: Journal of Colloid and Interface Science, Vol. 545, 01.03.2019, p. 162-171.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Quality-by-design in nanomedicine: Highly systematic optimization of lipid-polymer hybrid nanoparticles for efficacious and safe intracellular delivery of cargo siRNA. / Zeng, Xianghui; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    2017. Abstract from 2nd Gazi Pharma Symposium Series, Ankara, Turkey.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  47. Published

    Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection. / Møller, Laura Hyrup; Macherius, André; Hansen, Thomas Hesselhøj; Nielsen, Hanne Mørck; Cornett, Claus; Østergaard, Jesper; Stürup, Stefan; Gammelgaard, Bente.

    In: Journal of Analytical Atomic Spectrometry, Vol. 31, 2016, p. 1877-1884.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics. / Baker, Kristin R.; Jana, Bimal; Hansen, Anna Mette; Nielsen, Hanne Morck; Franzyk, Henrik; Guardabassi, Luca.

    In: Frontiers in Cellular and Infection Microbiology, Vol. 9, 02.07.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators. / Baker, Kristin R; Jana, Bimal; Hansen, Anna Mette; Vissing, Karina Juul; Nielsen, Hanne Mørck; Franzyk, Henrik; Guardabassi, Luca.

    In: International Journal of Antimicrobial Agents, Vol. 53, 2019, p. 868-872.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers. / Kristensen, Mie; Nielsen, Hanne Mørck.

    2015. Poster session presented at Crossing Biological Barriers, Dresden, Germany.

    Research output: Contribution to conferencePosterResearchpeer-review

ID: 1299091