David E. Gloriam

David E. Gloriam

Professor


  1. 2013
  2. Published

    The contribution of atom accessibility to site of metabolism models for cytochromes P450. / Rydberg, Patrik; Rostkowski, M.; Gloriam, D.E.; Olsen, L.

    In: Molecular Pharmaceutics, Vol. 10, No. 4, 01.04.2013, p. 1216-1223.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues : novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties. / Jensen, Anders A; Plath, Niels; Pedersen, Martin H. F.; Isberg, Vignir; Krall, Jacob; Wellendorph, Petrine; Stensbøl, Tine B.; Gloriam, David E.; Krogsgaard-Larsen, Povl; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 3, 14.02.2013, p. 1211-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    3-Substituted 2-phenyl-indoles : Privileged structures for medicinal chemistry. / Johansson, Karl Henrik; Jørgensen, T.B.; Gloriam, D.E.; Bräuner-Osborne, Hans; Pedersen, D.S.

    In: R S C Advances, Vol. 3, No. 3, 21.01.2013, p. 945-960.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Chemogenomics of allosteric binding sites in GPCRs. / Gloriam, David E.

    In: Drug Discovery Today: Technologies, Vol. 10, No. 2, 2013, p. e307-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-ht2 receptors. / Isberg, Vignir; Paine, James; Leth-Petersen, Sebastian; Kristensen, Jesper Langgaard; Gloriam, David E.

    In: P L o S One, Vol. 8, No. 11, e78515, 2013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2012
  8. Published

    Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. / Thiele, Stefanie; Malmgaard-Clausen, Mikkel; Engel-Andreasen, Jens; Steen, Anne; Rummel, Pia C; Nielsen, Mads C; Gloriam, David E.; Frimurer, Thomas Michael; Ulven, Trond; Rosenkilde, Mette.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 18, 27.09.2012, p. 8164-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators. / Mølck, Christina; Harpsøe, Kasper; Gloriam, David E; Clausen, Rasmus P; Madsen, Ulf; Pedersen, Lars; Jimenez, Hermogenes N; Nielsen, Søren M; Mathiesen, Jesper M; Bräuner-Osborne, Hans.

    In: Molecular Pharmacology, Vol. 82, No. 5, 2012, p. 929-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators. / Kaae, Birgitte H; Harpsøe, Kasper; Kvist, Trine; Mathiesen, Jesper M; Mølck, Christina; Gloriam, David E; Jimenez, Hermogenes N; Uberti, Michelle A; Nielsen, Søren M; Nielsen, Birgitte; Bräuner-Osborne, Hans; Sauerberg, Per; Clausen, Rasmus Prætorius; Madsen, Ulf.

    In: ChemMedChem, Vol. 7, No. 3, 2012, p. 440-451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2011
  12. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor. / Gloriam, David E.; Wellendorph, Petrine; Johansen, Lars Dan; Thomsen, Alex Rojas Bie; Phonekeo, Karina; Pedersen, Daniel Sejer; Bräuner-Osborne, Hans.

    In: Chemistry & Biology, Vol. 18, No. 11, 23.11.2011, p. 1489-1498.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Binding Mode of a Novel MPEP-Derived Metabotropic Glutamate Receptor Subtype 5 (mGluR5) NAM, 1,3-Bis(pyridin-2-ylethynyl)Benzene. / Molck, C.; Harpsoe, K.; Gloriam, D. E.; Kaae, B. H.; Jimenez, H. N.; Uberti, M. A.; Topiol, S.; Clausen, Rasmus Prætorius; Madsen, U.; Nielsen, S. M.; Mathiesen, J. M.; Brauner-Osborne, H.

    In: Current Neuropharmacology, Vol. 9, 09.2011, p. 43-43.

    Research output: Contribution to journalConference abstract in journalResearch

ID: 5953796