David E. Gloriam

David E. Gloriam

Professor


  1. Published

    Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at -Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters. / Giraudo, Alessandro; Krall, Jacob; Bavo, Francesco; Nielsen, Birgitte; Kongstad, Kenneth Thermann; Rolando, Barbara; De Blasio, Rosella; Gloriam, David E; Löffler, Rebekka; Thiesen, Louise; Harpsøe, Kasper; Frydenvang, Karla; Boschi, Donatella; Wellendorph, Petrine; Lolli, Marco L; Jensen, Anders A.; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 62, No. 12, 27.06.2019, p. 5797-5809.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations. / Ísberg, Vignir; Balle, Thomas; Sander, Tommy; Jørgensen, Flemming Steen; Gloriam, David Erik Immanuel.

    In: Journal of Chemical Information and Modeling, Vol. 51, No. 2, 28.02.2011, p. 315-325.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    G protein-coupled receptor pharmacology-The next generation. / Bräuner-Osborne, Hans; Rosenkilde, Mette M; Gether, Ulrik; Gloriam, David E.

    In: Basic & Clinical Pharmacology & Toxicology, 13.07.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    GPCRDB : an information system for G protein-coupled receptors. / Ísberg, Vignir; Vroling, Bas; van der Kant, Rob; Li, Kang; Vriend, Gert; Gloriam, David.

    In: Nucleic Acids Research, Vol. 42, No. Database issue, 01.2014, p. D422-D425.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    GPCRdb : an information system for G protein-coupled receptors. / Isberg, Vignir; Mordalski, Stefan; Munk, Christian; Rataj, Krzysztof; Harpsøe, Kasper; Hauser, Alexander S; Vroling, Bas; Bojarski, Andrzej J; Vriend, Gert; Gloriam, David E.

    In: Nucleic Acids Research, Vol. 44, No. D1, 04.01.2016, p. D356-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    GPCRdb in 2018 : adding GPCR structure models and ligands. / Pándy-Szekeres, Gáspár; Munk, Christian; Tsonkov, Tsonko M; Mordalski, Stefan; Harpsøe, Kasper; Hauser, Alexander S; Bojarski, Andrzej J; Gloriam, David E.

    In: Nucleic Acids Research, Vol. 46, No. D1, gkx1109, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    GPCRdb: The G protein-coupled receptor database - an introduction. / Munk, C; Isberg, V; Mordalski, S; Harpsøe, K; Rataj, K; Hauser, A S; Kolb, P; Bojarski, A J; Vriend, G; Gloriam, D E.

    In: British Journal of Pharmacology, Vol. 173, No. 14, 07.2016, p. 2195-207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Generic GPCR residue numbers - aligning topology maps while minding the gaps. / Isberg, Vignir; de Graaf, Chris; Bortolato, Andrea; Cherezov, Vadim; Katritch, Vsevolod; Marshall, Fiona H; Mordalski, Stefan; Pin, Jean-Philippe; Stevens, Raymond C; Vriend, Gerrit; Gloriam, David E.

    In: Trends in Pharmacological Sciences, Vol. 36, No. 1, 01.01.2015, p. 22-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. High species variation within the repertoire of trace amine receptors. / Gloriam, David E.; Bjarnadóttir, T K; Schiöth, H B; Fredriksson, R.

    In: Annals of the New York Academy of Sciences, 04.2005.

    Research output: Contribution to journalConference articleResearch

  10. Published

    How can I teach to maximize the learning of “Roberts” (slow/nonambitious) and “Susans” (fast/ambitious)? Improving University Science Teaching and Learning - Pedagogical Projects 2008. / Gloriam, David E.

    Improving University Science Teaching and Learning - Pedagogical Projects 2008. ed. / Frederik V. Christiansen; Camilla Rump; Lise Degn. Vol. 1 København : Department of Science Education, University of Copenhagen, Denmark, 2008. p. 227-244.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  11. Published

    Identification and characterization of small molecular NPR-B receptor antagonists. / Andresen, Henriette; Moltzau, Lise; Fagerheim, Steffen; Gloriam, David; Bach, Trond; Levy, Finn.

    In: BMC Pharmacology and Toxicology, Vol. 16, No. Suppl 1, 01.01.2015, p. A70.

    Research output: Contribution to journalJournal articleCommunication

  12. Published

    Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method. / Frandsen, Ida Osborn; Boesgaard, Michael W; Fidom, Kimberley; Hauser, Alexander S; Isberg, Vignir; Bräuner-Osborne, Hans; Wellendorph, Petrine; Gloriam, David E.

    In: Scientific Reports, Vol. 7, No. 1, 4829, 06.07.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Identification of a novel scaffold for a small molecule GPR139 receptor agonist. / Nøhr, Anne Cathrine; Shehata, Mohamed A; Palmer, Daniel; Pokhrel, Rina; Vallianou, Maria; Foster, Simon R; Gentry, Patrick R; Gloriam, David E; Bräuner-Osborne, Hans.

    In: Scientific Reports, Vol. 9, No. 1, 07.03.2019, p. 3802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Identification of the first surrogate agonists for the G protein-coupled receptor GPR132. / Shehata, Mohamed A.; Christensen, Hanna Belcik; Isberg, Vignir; Pedersen, Daniel Sejer; Bender, Andreas; Bräuner-Osborne, Hans; Gloriam, David E.

    In: RSC Advances, Vol. 5, 2015, p. 48551-48557.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    In silico identification of novel G protein-coupled receptors. / Davies, Matthew N; Gloriam, David E; Flower, Darren R.

    Methods for the discovery and characterization of G protein-coupled receptors. ed. / Craig W Stevens. Vol. 60 New York : Humana Press, 2011. p. 3-18 (Neuromethods, Vol. 60).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  16. Published

    Integrating structural and mutagenesis data to elucidate GPCR ligand binding. / Munk, Christian; Harpsøe, Kasper; Hauser, Alexander S; Isberg, Vignir; Gloriam, David E.

    In: Current Opinion in Pharmacology, Vol. 30, 10.2016, p. 51-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Kemogenomik : Receptoren set fra lægemiddelstoffets synspunkt. / Johansson, Henrik; Jørgensen, Tanja Bøgeløv; Gloriam, David E; Wellendorph, Petrine; Johansen, Lars Dan; Pedersen, Daniel Sejer; Bräuner-Osborne, Hans.

    In: Dansk Kemi, Vol. 92, No. 11, 2011, p. 22-26.

    Research output: Contribution to journalJournal articleResearch

  18. Published

    Kemogenomik : receptoren set fra lægemiddelstoffets synspunkt. / Gloriam, David Erik Immanuel; Wellendorph, Petrine; Johansen, Lars Dan; Pedersen, Daniel Sejer; Bräuner-Osborne, Hans.

    In: Lægemiddelforskning, Vol. 2010, 12.2010, p. 28-30.

    Research output: Contribution to journalJournal articleCommunication

  19. Published

    Methods for the successful application of chemogenomics to GPCR drug design. / Garland, Stephen L (Editor); Gloriam, David E (Editor).

    In: Current Topics in Medicinal Chemistry, Vol. 11, No. 15, 2011, p. 1870-1871.

    Research output: Contribution to journalEditorialResearch

  20. Published

    Minimum information about a protein affinity reagent (MIAPAR). / Bourbeillon, Julie; Orchard, Sandra; Benhar, Itai; Borrebaeck, Carl; de Daruvar, Antoine; Dübel, Stefan; Frank, Ronald; Gibson, Frank; Gloriam, David Erik Immanuel; Haslam, Niall; Hiltker, Tara; Humphrey-Smith, Ian; Hust, Michael; Juncker, David; Koegl, Manfred; Konthur, Zoltàn; Korn, Bernhard; Krobitsch, Sylvia; Muyldermans, Serge; Nygren, Per-Åke; Palcy, Sandrine; Polic, Bojan; Rodriguez, Henry; Sawyer, Alan; Schlapshy, Martin; Snyder, Michael; Stoevesandt, Oda; Taussig, Michael J; Templin, Markus; Uhlen, Matthias; van der Maarel, Silvere; Wingren, Christer; Hermjakob, Henning; Sherman, David.

    In: Nature Biotechnology, Vol. 28, No. 7, 2010, p. 650-653.

    Research output: Contribution to journalJournal articleResearch

  21. Published

    Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. / Thiele, Stefanie; Malmgaard-Clausen, Mikkel; Engel-Andreasen, Jens; Steen, Anne; Rummel, Pia C; Nielsen, Mads C; Gloriam, David E.; Frimurer, Thomas Michael; Ulven, Trond; Rosenkilde, Mette.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 18, 27.09.2012, p. 8164-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs. / Krall, Jacob; Jensen, Claus Hatt; Bavo, Francesco; Falk-Petersen, Christina Birkedahl; Haugaard, Anne Stæhr; Vogensen, Stine Byskov; Tian, Yongsong; Nittegaard-Nielsen, Mia; Sigurdardóttir, Sara Björk; Kehler, Jan; Kongstad, Kenneth Thermann; Gloriam, David E.; Clausen, Rasmus Prætorius; Harpsøe, Kasper; Wellendorph, Petrine; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 60, No. 21, 2017, p. 9022-9039.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Nine new human Rhodopsin family G-protein coupled receptors : identification, sequence characterisation and evolutionary relationship. / Gloriam, David E.; Schiöth, Helgi B; Fredriksson, Robert.

    In: BBA General Subjects, Vol. 1722, No. 3, 15.04.2005, p. 235-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139. / Shehata, Mohamed A; Jensen, Anne Cathrine Nøhr; Lissa, Delphine; Bisig, Christoph; Isberg, Vignir; Andersen, Kirsten B; Harpsøe, Kasper; Björkling, Fredrik; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Scientific Reports, Vol. 6, 36681, 10.11.2016, p. 1-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Pharmacogenomics of GPCR Drug Targets. / Hauser, Alexander Sebastian; Chavali, Sreenivas; Masuho, Ikuo; Jahn, Leonie; Martemyanov, Kirill; Gloriam, David E.; Babu, Madan.

    In: Cell, Vol. 172, 01.2018, p. 41–54.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5953796