David E. Gloriam

David E. Gloriam

Professor


  1. Published

    The repertoire of trace amine G-protein-coupled receptors : large expansion in zebrafish. / Gloriam, David E.; Bjarnadóttir, Thóra K; Yan, Yi-Lin; Postlethwait, John H; Schiöth, Helgi B; Fredriksson, Robert.

    In: Molecular Phylogenetics and Evolution, Vol. 35, No. 2, 05.2005, p. 470-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Nine new human Rhodopsin family G-protein coupled receptors : identification, sequence characterisation and evolutionary relationship. / Gloriam, David E.; Schiöth, Helgi B; Fredriksson, Robert.

    In: BBA General Subjects, Vol. 1722, No. 3, 15.04.2005, p. 235-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Bigger is better in virtual drug screens. / Gloriam, David E.

    In: Nature, Vol. 566, No. 7743, 14.02.2019, p. 193-194.

    Research output: Contribution to journalLetterResearchpeer-review

  4. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor. / Gloriam, David E.; Wellendorph, Petrine; Johansen, Lars Dan; Thomsen, Alex Rojas Bie; Phonekeo, Karina; Pedersen, Daniel Sejer; Bräuner-Osborne, Hans.

    In: Chemistry & Biology, Vol. 18, No. 11, 23.11.2011, p. 1489-1498.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. The G protein-coupled receptor subset of the rat genome. / Gloriam, David E.; Fredriksson, Robert; Schiöth, Helgi B.

    In: B M C Genomics, Vol. 8, 2007, p. 338.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design. / Gloriam, David Erik Immanuel; Foord, Steven M; Blaney, Frank E; Garland, Stephen L.

    In: Journal of Medicinal Chemistry, Vol. 52, No. 14, 2009, p. 4429-4442.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Kemogenomik : receptoren set fra lægemiddelstoffets synspunkt. / Gloriam, David Erik Immanuel; Wellendorph, Petrine; Johansen, Lars Dan; Pedersen, Daniel Sejer; Bräuner-Osborne, Hans.

    In: Lægemiddelforskning, Vol. 2010, 12.2010, p. 28-30.

    Research output: Contribution to journalJournal articleCommunication

  8. Published

    A community standard format for the representation of protein affinity reagents. / Gloriam, David Erik Immanuel; Orchard, Sandra; Bertinetti, Daniela; Björling, Erik; Bongcam-Rudloff, Erik; Borrebaeck, Carl A K; Bourbeillon, Julie; Bradbury, Andrew R M; de Daruvar, Antoine; Dübel, Stefan; Frank, Ronald; Gibson, Toby J; Gold, Larry; Haslam, Niall; Herberg, Friedrich W; Hiltke, Tara; Hoheisel, Jörg D; Kerrien, Samuel; Koegl, Manfred; Konthur, Zoltán; Korn, Bernhard; Landegren, Ulf; Montecchi-Palazzi, Luisa; Palcy, Sandrine; Rodriguez, Henry; Schweinsberg, Sonja; Sievert, Volker; Stoevesandt, Oda; Taussig, Michael J; Ueffing, Marius; Uhlén, Mathias; van der Maarel, Silvère; Wingren, Christer; Woollard, Peter; Sherman, David J; Hermjakob, Henning.

    In: Molecular and Cellular Proteomics, Vol. 9, No. 1, 2010, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents. / Haitina, Tatjana; Fredriksson, Robert; Foord, Steven M; Schiöth, Helgi B; Gloriam, David E.

    In: B M C Genomics, Vol. 10, 2009, p. 24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structural insight to mutation effects uncover a common allosteric site in class C GPCRs. / Harpsøe, Kasper; Boesgaard, Michael W; Munk, Christian; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Bioinformatics (Oxford, England), Vol. 33, No. 8, btw784, 2017, p. 1116-1120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors - A Structural Perspective of Ligands and Mutants. / Harpsøe, Kasper; Isberg, Vignir; Tehan, Benjamin G; Weiss, Dahlia; Arsova, Angela; Marshall, Fiona H; Bräuner-Osborne, Hans; Gloriam, David E.

    In: Scientific Reports, Vol. 5, 13869, 11.09.2015, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Trends in GPCR drug discovery: new agents, targets and indications. / Hauser, Alexander Sebastian; Gloriam, David E.; Attwood, Misty M.; Rask-Andersen, Mathias ; Schiöth, Helgi B. .

    In: Nature Reviews. Drug Discovery, Vol. 16, 178, 27.10.2017, p. 829-842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Pharmacogenomics of GPCR Drug Targets. / Hauser, Alexander Sebastian; Chavali, Sreenivas; Masuho, Ikuo; Jahn, Leonie; Martemyanov, Kirill; Gloriam, David E.; Babu, Madan.

    In: Cell, Vol. 172, 01.2018, p. 41–54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-ht2 receptors. / Isberg, Vignir; Paine, James; Leth-Petersen, Sebastian; Kristensen, Jesper Langgaard; Gloriam, David E.

    In: P L o S One, Vol. 8, No. 11, e78515, 2013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Generic GPCR residue numbers - aligning topology maps while minding the gaps. / Isberg, Vignir; de Graaf, Chris; Bortolato, Andrea; Cherezov, Vadim; Katritch, Vsevolod; Marshall, Fiona H; Mordalski, Stefan; Pin, Jean-Philippe; Stevens, Raymond C; Vriend, Gerrit; Gloriam, David E.

    In: Trends in Pharmacological Sciences, Vol. 36, No. 1, 01.01.2015, p. 22-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    GPCRdb : an information system for G protein-coupled receptors. / Isberg, Vignir; Mordalski, Stefan; Munk, Christian; Rataj, Krzysztof; Harpsøe, Kasper; Hauser, Alexander S; Vroling, Bas; Bojarski, Andrzej J; Vriend, Gert; Gloriam, David E.

    In: Nucleic Acids Research, Vol. 44, No. D1, 04.01.2016, p. D356-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Correction : Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors (PLoS ONE). / Isberg, Vignir; Paine, James; Leth-Petersen, Sebastian; Kristensen, Jesper L.; Gloriam, David E.

    In: PLOS ONE, Vol. 9, No. 1, 17.01.2014.

    Research output: Contribution to journalComment/debateResearchpeer-review

  18. Published

    Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues : novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties. / Jensen, Anders A; Plath, Niels; Pedersen, Martin H. F.; Isberg, Vignir; Krall, Jacob; Wellendorph, Petrine; Stensbøl, Tine B.; Gloriam, David E.; Krogsgaard-Larsen, Povl; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 3, 14.02.2013, p. 1211-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The orphan G protein-coupled receptor GPR139 is activated by the peptides : Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW. / Jensen, Anne Cathrine Nøhr; Shehata, Mohamed A; Hauser, Alexander S; Isberg, Vignir; Mokrosinski, Jacek; Farooqi, I Sadaf; Pedersen, Daniel Sejer; Gloriam, David E; Bräuner-Osborne, Hans.

    In: Neurochemistry International, Vol. 102, 01.01.2017, p. 105-113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Structural Mapping of Adenosine Receptor Mutations : Ligand Binding and Signaling Mechanisms. / Jespers, Willem; Schiedel, Anke C; Heitman, Laura H; Cooke, Robert M; Kleene, Lisa; van Westen, Gerard J P; Gloriam, David E; Müller, Christa E; Sotelo, Eddy; Gutiérrez-de-Terán, Hugo.

    In: Trends in Pharmacological Sciences, Vol. 39, No. 1, 01.2018, p. 75-89.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Kemogenomik : Receptoren set fra lægemiddelstoffets synspunkt. / Johansson, Henrik; Jørgensen, Tanja Bøgeløv; Gloriam, David E; Wellendorph, Petrine; Johansen, Lars Dan; Pedersen, Daniel Sejer; Bräuner-Osborne, Hans.

    In: Dansk Kemi, Vol. 92, No. 11, 2011, p. 22-26.

    Research output: Contribution to journalJournal articleResearch

  22. Published

    Selective Allosteric Antagonists for the G Protein-Coupled Receptor GPRC6A Based on the 2-Phenylindole Privileged Structure Scaffold. / Johansson, Henrik; Boesgaard, Michael Worch; Nørskov-Lauritsen, Lenea; Larsen, Inna; Kuhne, Sebastiaan; Gloriam, David E; Bräuner-Osborne, Hans; Sejer Pedersen, Daniel.

    In: Journal of Medicinal Chemistry, Vol. 58, No. 22, 25.11.2015, p. 8938-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    3-Substituted 2-phenyl-indoles : Privileged structures for medicinal chemistry. / Johansson, Karl Henrik; Jørgensen, T.B.; Gloriam, D.E.; Bräuner-Osborne, Hans; Pedersen, D.S.

    In: R S C Advances, Vol. 3, No. 3, 21.01.2013, p. 945-960.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators. / Kaae, Birgitte H; Harpsøe, Kasper; Kvist, Trine; Mathiesen, Jesper M; Mølck, Christina; Gloriam, David E; Jimenez, Hermogenes N; Uberti, Michelle A; Nielsen, Søren M; Nielsen, Birgitte; Bräuner-Osborne, Hans; Sauerberg, Per; Clausen, Rasmus Prætorius; Madsen, Ulf.

    In: ChemMedChem, Vol. 7, No. 3, 2012, p. 440-451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Discovery of 2-(Imidazo[1,2-b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites. / Krall, Jacob; Bavo, Francesco; Falk-Petersen, Christina B; Jensen, Claus Hatt; Nielsen, Julie Olsson; Tian, Yongsong; Anglani, Valeria; Kongstad, Kenneth Thermann; Piilgaard, Louise; Nielsen, Birgitte; Gloriam, David E; Kehler, Jan; Jensen, Anders A.; Harpsøe, Kasper; Wellendorph, Petrine; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 62, No. 5, 14.03.2019, p. 2798-2813.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5953796