Bolette Hartmann

Bolette Hartmann

Associate Professor


  1. 1994
  2. Published

    Proglucagon processing in porcine and human pancreas. / Holst, J J; Bersani, M; Johnsen, A H; Kofod, Hans; Hartmann, B; Orskov, C.

    In: Journal of Biological Chemistry, Vol. 269, No. 29, 1994, p. 18827-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1999
  4. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat : effects of dietary fibre. / Thulesen, J; Hartmann, B; Nielsen, C; Holst, J J; Poulsen, Steen Seier.

    In: Gut, Vol. 45, No. 5, 11.1999, p. 672-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2000
  6. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice. / Hartmann, B; Thulesen, J; Kissow, Hannelouise; Thulesen, S; Orskov, C; Ropke, C; Poulsen, S S; Holst, J J.

    In: Endocrinology, Vol. 141, No. 11, 2000, p. 4013-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells. / Schmidt, P T; Hartmann, B; Bregenholt, S; Holst, Jens Juul; Claesson, Mogens Helweg.

    In: Scandinavian Journal of Gastroenterology, Vol. 35, No. 5, 01.05.2000, p. 522-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon. / Jeppesen, P B; Hartmann, B; Thulesen, J; Hansen, B S; Holst, J J; Poulsen, Steen Seier; Mortensen, P B.

    In: Gut, Vol. 47, No. 3, 09.2000, p. 370-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat : distribution and binding of i.v. injected (125)I-GLP-2. / Thulesen, J; Hartmann, B; Orskov, C; Jeppesen, P B; Holst, J J; Poulsen, Steen Seier.

    In: Peptides, Vol. 21, No. 10, 10.2000, p. 1511-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2001
  11. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection. / Thulesen, J; Hartmann, B; Kissow, Hannelouise; Jeppesen, P B; Orskov, C; Holst, J J; Poulsen, S S.

    In: Digestive Diseases and Sciences, Vol. 46, No. 2, 2001, p. 379-88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon. / Jeppesen, P B; Hartmann, B; Thulesen, J; Graff, J; Lohmann, J; Hansen, B S; Tofteng, F; Poulsen, Steen Seier; Madsen, J L; Holst, J J; Mortensen, P B.

    In: Gastroenterology, Vol. 120, No. 4, 03.2001, p. 806-815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2002
  14. Published

    Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon. / Haderslev, K V; Jeppesen, P B; Hartmann, B; Thulesen, J; Sorensen, H A; Graff, J; Tofteng, F; Poulsen, S S; Madsen, J L; Holst, J J; Staun, M; Mortensen, P B; Poulsen, Steen Seier.

    In: Scandinavian Journal of Gastroenterology, Vol. 37, No. 4, 01.04.2002, p. 392-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2003
  16. Published

    Injected TFF1 and TFF3 bind to TFF2-immunoreactive cells in the gastrointestinal tract in rats. / Poulsen, S S; Thulesen, J; Hartmann, B; Kissow, Hannelouise; Nexø, Ebba; Thim, L.

    In: Regulatory Peptides, Vol. 115, No. 2, 2003, p. 91-99.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects. / Sørensen, L B; Flint, A; Raben, A; Hartmann, B; Holst, Jens Juul; Astrup, A.

    In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, Vol. 27, No. 4, 04.2003, p. 450-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development. / Petersen, Yvette M; Hartmann, Bolette; Holst, Jens Juul; Le Huerou-Luron, Isabelle; Bjørnvad, Charlotte R; Sangild, Per T.

    In: Journal of Nutrition, Vol. 133, No. 6, 06.2003, p. 1781-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1. / Guan, Xinfu; Stoll, Barbara; Lu, Xiaofeng; Tappenden, Kelly A; Holst, Jens Juul; Hartmann, Bolette; Burrin, Douglas G.

    In: Gastroenterology, Vol. 125, No. 1, 07.2003, p. 136-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety. / Schmidt, P T; Näslund, E; Grybäck, P; Jacobsson, H; Hartmann, B; Holst, Jens Juul; Hellström, P M.

    In: Regulatory Peptides, Vol. 116, No. 1-3, 15.11.2003, p. 21-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2004
  22. Published

    Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum. / Hansen, Lene; Hartmann, Bolette; Mineo, Hitoshi; Holst, Jens Juul.

    In: Regulatory Peptides, Vol. 118, No. 1-2, 15.04.2004, p. 11-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets. / Niinikoski, Harri; Stoll, Barbara; Guan, Xinfu; Kansagra, Ketan; Lambert, Barry D; Stephens, John; Hartmann, Bolette; Holst, Jens Juul; Burrin, Douglas G.

    In: Journal of Nutrition, Vol. 134, No. 6, 06.2004, p. 1467-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice. / Thulesen, J; Hartmann, B; Hare, K J; Kissow, H; Ørskov, C; Holst, Jens Juul; Poulsen, S S.

    In: Gut, Vol. 53, No. 8, 08.2004, p. 1145-1150.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation : effects of different diet regimens. / Paris, Monique C; Fuller, Peter J; Carstensen, Bendix; Nagy, Eva; Taylor, Russell G; Sourial, Magdy; Holst, Jens Juul; Hartmann, Bolette; Binesm, Julie E.

    In: Digestive Diseases and Sciences, Vol. 49, No. 10, 10.2004, p. 1688-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2005
  27. Published

    Glucagon-like peptide-2 (GLP-2) response to enteral intake in children during anti-cancer treatment. / Andreassen, B U; Paerregaard, A; Schmiegelow, K; Rechnitzer, C; Heilman, C; Hartmann, B; Holst, Jens Juul; Michaelsen, K F.

    In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 40, No. 1, 01.2005, p. 48-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Tissue levels and post-prandial secretion of the intestinal growth factor, glucagon-like peptide-2, in controls and inflammatory bowel disease : comparison with peptide YY. / Schmidt, Peter T; Ljung, Tryggve; Hartmann, Bolette; Hare, Kristine J; Holst, Jens Juul; Hellström, Per M.

    In: European journal of gastroenterology & hepatology, Vol. 17, No. 2, 02.2005, p. 207-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome. / Martin, G R; Wallace, L E; Hartmann, B; Holst, Jens Juul; Demchyshyn, L; Toney, K; Sigalet, D L.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 288, No. 3, 03.2005, p. G431-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2007
  31. Published

    Glucagon-like peptide-2 in umbilical cord blood from mature infants. / Bodé, Susan; Hartmann, Bolette; Holst, Jens Juul; Greisen, Gorm.

    In: Neonatology, Vol. 91, No. 1, 2007, p. 49-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Disassociation of bone resorption and formation by GLP-2 : a 14-day study in healthy postmenopausal women. / Henriksen, Dennis B; Alexandersen, Peter; Hartmann, Bolette; Adrian, Charlotte L; Byrjalsen, Inger; Bone, Henry G; Holst, Jens Juul; Christiansen, Claus.

    In: Bone, Vol. 40, No. 3, 03.2007, p. 723-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate. / Holst, Jens Juul; Hartmann, Bolette; Gottschalck, Ida B; Jeppesen, Palle B; Miholic, Johannes; Henriksen, Dennis Bang.

    In: Scandinavian Journal of Gastroenterology, Vol. 42, No. 7, 07.2007, p. 814-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2008
  35. Published

    Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome. / Gottschalck, Ida B; Jeppesen, Palle B; Hartmann, Bolette; Holst, Jens Juul; Henriksen, Dennis B.

    In: Scandinavian Journal of Gastroenterology, Vol. 43, No. 11, 2008, p. 1304-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate. / Amin, Harish; Holst, Jens Juul; Hartmann, Bolette; Wallace, Laurie; Wright, Jim; Sigalet, David L.

    In: Pediatrics, Vol. 121, No. 1, 01.2008, p. e180-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2009
  38. Published

    Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD. / Henriksen, Dennis B; Alexandersen, Peter; Hartmann, Bolette; Adrian, Charlotte L; Byrjalsen, Inger; Bone, Henry G; Holst, Jens J; Christiansen, Claus.

    In: Bone, Vol. 45, No. 5, 2009, p. 833-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats. / Simonsen, L; Pilgaard, S; Orskov, C; Hartmann, B; Holst, Jens Juul; Deacon, C F.

    In: Diabetes, Obesity and Metabolism, Vol. 11, No. 9, 2009, p. 884-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2010
  41. Published

    The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin. / Rasmussen, Andreas Rosén; Viby, Niels-Erik; Hare, Kristine Juul; Hartmann, Bolette; Thim, Lars; Holst, Jens Juul; Poulsen, Steen Seier.

    In: Digestive Diseases and Sciences, Vol. 55, No. 10, 01.10.2010, p. 2785-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2011
  43. Published

    Glucagon-like peptide 2 (Glp-2) stimulates intestinal function during weaning. / Thymann, Thomas; Huërou-Luron, I. Le; Petersen, Y.M.; Hedemann, Mette Skou; Elnif, Jan; Jensen, B.B.; Hartmann, Bolette; Holst, Jens Juul; Sangild, Per Torp.

    44th annual meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, 2011: programme and abstract booklet. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), 2011. p. 202.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  44. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1. / Torekov, S S; Ma, L; Grarup, N; Hartmann, B; Hainerová, I A; Kielgast, U; Kissow, H; Rosenkilde, M; Lebl, J; Witte, D R; Jørgensen, T; Sandbaek, A; Lauritzen, T; Madsen, O D; Wang, J; Linneberg, A; Madsbad, S; Holst, J J; Hansen, T; Pedersen, O; GIANT Consortium.

    In: Diabetologia, Vol. 54, No. 11, 2011, p. 2820-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients. / Bremholm, Lasse; Hornum, Mads; Andersen, Ulrik B; Hartmann, Bolette; Holst, Jens Juul; Jeppesen, Palle Bekker.

    In: Regulatory Peptides, Vol. 168, No. 1-3, 2011, p. 32-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Reduction of parathyoid hormone levels. / Hartmann, Bolette (Inventor); B. Henriksen, Dennis (Inventor).

    Patent No.: US2010/0081,622. Sep 28, 2009.

    Research output: PatentResearch

  47. 2012
  48. Published

    Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine. / Kissow, Hannelouise; Viby, Niels-Erik; Hartmann, Bolette; Holst, Jens Juul; Timm, Michael; Thim, Lars; Poulsen, Steen Seier.

    In: Cancer Chemotherapy and Pharmacology. Supplement, Vol. 70, No. 1, 2012, p. 39-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome. / Lund, Pernille; Sangild, Per Torp; Aunsholt, L.; Hartmann, Bolette; Holst, Jens Juul; Mortensen, J.; Mortensen, P.B.; Jeppesen, P.B.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 9, 2012, p. 1059-1065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs. / Stoll, Barbara; Puiman, Patrycja Jolanta; Cui, Liwei; Chang, Xiaoyan; Benight, Nancy Marie; Bauchart-Thevret, Caroline; Hartmann, Bolette; Holst, Jens Juul; Burrin, Douglas Guy.

    In: Journal of Parenteral and Enteral Nutrition, Vol. 36, No. 5, 09.2012, p. 538-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model. / Barnes, Jennifer L; Hartmann, Bolette; Holst, Jens Juul; Tappenden, Kelly A.

    In: Journal of Parenteral and Enteral Nutrition, Vol. 36, No. 5, 09.2012, p. 524-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Glucagon-like peptide-1 as a treatment for chemotherapy-induced mucositis. / Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul; Poulsen, Steen Seier.

    In: Gut, 20.10.2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice. / Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul; Viby, Niels-Erik; Hansen, Lærke Schmidt; Rosenkilde, Mette Marie; Hare, Kristine Juul; Poulsen, Steen Seier.

    In: Regulatory Peptides, Vol. 179, No. 1-3, 10.11.2012, p. 91-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2013
  55. Published

    Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates. / Vegge, Andreas; Thymann, Thomas; Lund, Pernille; Stoll, Barbara; Bering, Stine Brandt; Hartmann, Bolette; Jelsing, Jacob; Qvist, Niels; Burrin, Douglas G; Jeppesen, Palle Bekker; Holst, Jens Juul; Sangild, Per T.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 305, No. 4, 2013, p. G277-G285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin. / Holst, Jens Juul; Deacon, Carolyn F.; Hartmann, Bolette; Pedersen, Jens.

    Handbook of Biologically Active Peptides . ed. / AJ Kastin. 2. ed. Elsevier, 2013. p. 1241-1250.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  57. Published

    Effect of glucagon-like peptide-2 exposure on bone resorption : Effectiveness of high concentration versus prolonged exposure. / Askov-Hansen, Carsten; Jeppesen, Palle B; Lund, Pernille; Hartmann, Bolette; Holst, Jens Juul; Henriksen, Dennis B.

    In: Regulatory Peptides, Vol. 181, 10.02.2013, p. 4-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass. / Dirksen, C; Jørgensen, N B; Bojsen-Møller, K N; Kielgast, U; Jacobsen, S H; Clausen, T R; Worm, D; Hartmann, B; Rehfeld, J F; Damgaard, M; Madsen, J L; Madsbad, S; Holst, Jens Juul; Hansen, D L.

    In: International Journal of Obesity, Vol. 37, 19.02.2013, p. 1452-1459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty. / Plamboeck, Astrid; Veedfald, Simon; Deacon, Carolyn F; Hartmann, Bolette; Wettergren, Andre; Svendsen, Lars Bo; Meisner, Søren; Hovendahl, Claus; Vilsboll, Tina; Knop, Filip K; Holst, Jens Juul.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 304, 18.04.2013, p. G1117-G1127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty. / Plamboeck, Astrid; Veedfald, Simon; Deacon, Carolyn; Hartmann, Bolette; Wettergren, Andre; Svendsen, Lars Bo; Meisner, Søren; Hovendal, Claus; Knop, Filip Krag; Vilsbøll, Tina; Holst, Jens Juul.

    In: European Journal of Endocrinology, Vol. 169, 23.05.2013, p. 187-201.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    A dose-equivalent comparison of the effects of continuous subcutaneous glucagon-like peptide 2 (GLP-2) infusions versus meal related GLP-2 injections in the treatment of short bowel syndrome (SBS) patients. / Naimi, R M; Madsen, K B; Askov-Hansen, C; Brandt, C F; Hartmann, B; Holst, Jens Juul; Mortensen, P B; Jeppesen, P B.

    In: Regulatory Peptides, Vol. 184, No. 10, 10.06.2013, p. 47-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Acute effects of continuous infusions of glucagon-like peptide (GLP)-1, GLP-2 and the combination (GLP-1+GLP-2) on intestinal absorption in short bowel syndrome (SBS) patients. A placebo-controlled study. / Madsen, K B; Askov-Hansen, C; Naimi, R M; Brandt, C F; Hartmann, B; Holst, Jens Juul; Mortensen, P B; Jeppesen, P B.

    In: Regulatory Peptides, Vol. 184, No. 10, 10.06.2013, p. 30-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients. / Sigalet, David L; Kravarusic, Dragan; Butzner, Decker; Hartmann, Bolette; Holst, Jens Juul; Meddings, Jon.

    In: Canadian Journal of Gastroenterology, Vol. 27, No. 10, 10.2013, p. 587-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males. / Lund, Michael Taulo; Taudorf, Lærke; Hartmann, Bolette; Helge, Jørn Wulff; Holst, Jens Juul; Dela, Flemming.

    In: European Journal of Applied Physiology, Vol. 113, No. 11, 01.11.2013, p. 2737-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 2014
  66. Published

    Glucagon-like peptide 2 treatment may improve intestinal adaptation during weaning. / Thymann, Thomas; Le Huërou-Luron, I; Petersen, Y M; Hedemann, Mette Skou; Elinf, J; Jensen, B B; Holst, Jens Juul; Hartmann, Bolette; Sangild, Per Torp.

    In: Journal of Animal Science, Vol. 92, No. 5, 2014, p. 2070-2079.

    Research output: Contribution to journalJournal articleResearchpeer-review

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