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Anja Bengtsson

Anja Bengtsson

    Member of:

    • TARGETS team

    My research is focused on malaria to investigate how malaria parasites inside erythrocytes interact with the host. In particular, I focus on malaria parasites binding to ICAM-1 expressed at the brain endothelium and on the development of a cerebral malaria vaccine.

     

    Current research

    Keywords

    Receptor-ligand interactions; recombinant protein expression; antigen design; poly- and monoclonal antibody generation and characterization; immunoassays; cell-to-cell adhesion assays; flow cytometry; malaria infected erythrocytes; primary and immortalized cells; vaccine development; VLP

    Selected publications

    1. Published

      Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

      Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & Jensen, A. T. R. 8 Mar 2017 In : Cell Host & Microbe. 21, 3, p. 403-414 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding

      Lennartz, F., Bengtsson, A., Olsen, R. W., Joergensen, L., Brown, A., Remy, L., Man, P., Forest, E., Barfod, L. K., Adams, Y., Higgins, M. K. & Jensen, A. T. R. 2015 In : Journal of immunology (Baltimore, Md. : 1950). 195, 7, p. 3273-83 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 5463745