When to image carotid plaque inflammation with FDG PET/CT

Research output: Contribution to journalJournal articleResearchpeer-review

Martin Græbe, Lise Borgwardt, Liselotte Højgaard, Henrik Hegaard Sillesen, Andreas Kjær

Quantification of 18-fluorodeoxyglucose (FDG) uptake in inflamed high-risk carotid atherosclerotic plaques is challenged by the spatial resolution of positron emission tomography (PET) and luminal blood activity. Late acquisition protocols have been used to overcome these challenges to enhance the contrast between the plaque and blood-pool FDG activity. However, for prospective studies the late acquisition is inconvenient for the patient and staff, and most retrospective studies of plaque uptake use data from early acquisition protocols. The objective was to evaluate changes in the quantification methods of FDG uptake in carotid artery plaques between early and late PET scans.
Original languageEnglish
JournalNuclear Medicine Communications
Volume31
Issue number9
Pages (from-to)773-9
Number of pages7
ISSN0143-3636
DOIs
Publication statusPublished - 1 Sep 2010

ID: 34045080