Ultrastructural immunocytochemical localization of chondroitin sulfate proteoglycan in Bruch's membrane of the rat.
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Ultrastructural immunocytochemical localization of chondroitin sulfate proteoglycan in Bruch's membrane of the rat. / Lin, W L; Essner, E; McCarthy, K J; Couchman, J R.
In: Investigative Ophthalmology & Visual Science, Vol. 33, No. 6, 1992, p. 2072-5.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Ultrastructural immunocytochemical localization of chondroitin sulfate proteoglycan in Bruch's membrane of the rat.
AU - Lin, W L
AU - Essner, E
AU - McCarthy, K J
AU - Couchman, J R
N1 - Keywords: Animals; Antibodies, Monoclonal; Basement Membrane; Bruch Membrane; Capillaries; Chondroitin Sulfates; Choroid; Female; Immunoenzyme Techniques; Microscopy, Immunoelectron; Pigment Epithelium of Eye; Proteoglycans; Rats; Rats, Inbred Lew
PY - 1992
Y1 - 1992
N2 - Two monoclonal antibodies (Mab 4D5 and 2D6) raised against the core protein of a basement membrane chondroitin sulfate proteoglycan from Reichert's membrane of the rat, were used for ultrastructural immunoperoxidase localization of this protein in Bruch's membrane of the rat. Immunoreactivity for both antibodies was found in the basal lamina (basement membrane) of the choriocapillary endothelium and retinal pigment epithelium, in collagen fibers in the collagenous zones, and surrounding the elastic layer.
AB - Two monoclonal antibodies (Mab 4D5 and 2D6) raised against the core protein of a basement membrane chondroitin sulfate proteoglycan from Reichert's membrane of the rat, were used for ultrastructural immunoperoxidase localization of this protein in Bruch's membrane of the rat. Immunoreactivity for both antibodies was found in the basal lamina (basement membrane) of the choriocapillary endothelium and retinal pigment epithelium, in collagen fibers in the collagenous zones, and surrounding the elastic layer.
M3 - Journal article
C2 - 1582813
VL - 33
SP - 2072
EP - 2075
JO - Investigative Ophthalmology & Visual Science
JF - Investigative Ophthalmology & Visual Science
SN - 0146-0404
IS - 6
ER -
ID: 5165934