Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia

Research output: Contribution to journalJournal articleResearchpeer-review

Karen Kleberg, Gerda Majgaard Jensen, Dan Ploug Christensen, Morten Lundh, Lars Groth Grunnet, Svend Knuhtsen, Steen Seier Poulsen, Mark Berner Hansen, Niels Bindslev

The pathogenesis of colorectal neoplasia is still unresolved but has been associated with alterations in epithelial clearance of xenobiotics and metabolic waste products. The aim of this study was to functionally characterize the transport of cyclic nucleotides in colonic biopsies from patients with and without colorectal neoplasia.
Original languageEnglish
JournalBMC gastroenterology
Volume12
Issue number78
Pages (from-to)78
Number of pages12
ISSN1471-230X
DOIs
Publication statusPublished - 2012

    Research areas

  • Aged, Aged, 80 and over, Basement Membrane, Colon, Colorectal Neoplasms, Cyclic AMP, Dinoprostone, Endoplasmic Reticulum, Female, Goblet Cells, Golgi Apparatus, Humans, Intestinal Mucosa, Male, Middle Aged, Multidrug Resistance-Associated Proteins, Organic Anion Transporters

ID: 38187611