Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
Research output: Contribution to journal › Journal article › Research › peer-review
Elton L. Borges, Marta T. Ignasiak, Yuliia Velichenko, Gelson Perin, Craig A. Hutton, Michael J. Davies, Carl H. Schiesser
Novel stable tellurium-containing carbohydrate derivatives are prepared from hexitols and pentitols through a double nucleophilic substitution with NaHTe in PEG-400. These tellurosugars react at very high rates with two-electron oxidants, including hypochlorous and peroxynitrous acid, formed at sites of inflammation, and show considerable promise as protective agents against oxidative damage.
|Publication status||Published - 25 Mar 2018|