Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives

Research output: Contribution to journalJournal articleResearchpeer-review

Elton L. Borges, Marta T. Ignasiak, Yuliia Velichenko, Gelson Perin, Craig A. Hutton, Michael J. Davies, Carl H. Schiesser

Novel stable tellurium-containing carbohydrate derivatives are prepared from hexitols and pentitols through a double nucleophilic substitution with NaHTe in PEG-400. These tellurosugars react at very high rates with two-electron oxidants, including hypochlorous and peroxynitrous acid, formed at sites of inflammation, and show considerable promise as protective agents against oxidative damage.
Original languageEnglish
JournalChemical Communications
Volume54
Issue number24
Pages (from-to)2990-2993
ISSN1359-7345
DOIs
Publication statusPublished - 25 Mar 2018

ID: 210610293