Genome-wide association study of genetic variants in LPS-stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α cytokine response in a Danish Cohort

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Margit Hørup Larsen, Anders Albrechtsen, Lise Wegner Thørner, Thomas Werge, Thomas Hansen, Ulrik Gether, Eva Haastrup, Henrik Ullum

Cytokine response plays a vital role in various human lipopolysaccharide (LPS) infectious and inflammatory diseases. This study aimed to find genetic variants that might affect the levels of LPS-induced interleukin (IL)-6, IL-8, IL-10, IL-1ra and tumor necrosis factor (TNF)-α cytokine production.
Original languageEnglish
Article numbere66262
JournalPLOS ONE
Volume8
Issue number6
Number of pages6
ISSN1932-6203
DOIs
Publication statusPublished - 2013

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