Endoscopic retrograde cholangiopancreatography causes reduced myocardial blood flow

Research output: Contribution to journalJournal articleResearchpeer-review

M Christensen, H W Hendel, V Rasmussen, L Højgaard, S Schulze, J Rosenberg

BACKGROUND AND STUDY AIMS: Previous studies have shown that up to 50% of healthy patients may develop ST-segment changes during upper gastrointestinal endoscopy. The aim of the study was to evaluate myocardial blood flow in patients during endoscopic retrograde cholangiopancreatography (ERCP).

PATIENTS AND METHODS: 11 patients scheduled for ERCP were monitored with a Holter tape recorder and underwent myocardial perfusion scintigraphies, to evaluate myocardial perfusion at rest and during ERCP.

RESULTS: Ten patients completed the study. Eight patients had no sign of myocardial ischemia with either of the two methods, while two patients developed signs of ischemia during ERCP with both the Holter tape recording and on myocardial scintigraphy (P = 0.02).

CONCLUSIONS: Patients undergoing ERCP may develop true myocardial ischemia with reduced myocardial blood flow. Although this is a small-scale study, these findings strongly support the use of alternative methods for diagnostic evaluation of the pancreatic duct and biliary tree.

Original languageEnglish
JournalEndoscopy
Volume34
Issue number10
Pages (from-to)797-800
Number of pages4
ISSN0013-726X
DOIs
Publication statusPublished - Oct 2002

    Research areas

  • Aged, Cholangiopancreatography, Endoscopic Retrograde, Coronary Circulation, Electrocardiography, Ambulatory, Female, Humans, Male, Middle Aged, Myocardial Ischemia, Pancreatic Ducts, Journal Article, Research Support, Non-U.S. Gov't

ID: 165882744