Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues.

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Standard

Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues. / McCarthy, K J; Couchman, J R.

In: Journal of Histochemistry and Cytochemistry, Vol. 38, No. 10, 1990, p. 1479-86.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

McCarthy, KJ & Couchman, JR 1990, 'Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues.', Journal of Histochemistry and Cytochemistry, vol. 38, no. 10, pp. 1479-86.

APA

McCarthy, K. J., & Couchman, J. R. (1990). Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues. Journal of Histochemistry and Cytochemistry, 38(10), 1479-86.

Vancouver

McCarthy KJ, Couchman JR. Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues. Journal of Histochemistry and Cytochemistry. 1990;38(10):1479-86.

Author

McCarthy, K J ; Couchman, J R. / Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues. In: Journal of Histochemistry and Cytochemistry. 1990 ; Vol. 38, No. 10. pp. 1479-86.

Bibtex

@article{87e6d920597d11dd8d9f000ea68e967b,
title = "Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues.",
abstract = "Heparan sulfate proteoglycans have been described as the major proteoglycan component of basement membranes. However, previous investigators have also provided evidence for the presence of chondroitin sulfate glycosaminoglycan in these structures. Recently we described the production and characterization of core protein-specific monoclonal antibodies (MAb) against a chondroitin sulfate proteoglycan (CSPG) present in Reichert's membrane, a transient extra-embryonic structure of rodents. This CSPG was also demonstrated to be present in adult rat kidney. We report here the tissue distribution of epitopes recognized by these MAb. The ubiquitous presence of these epitopes in the basement membranes of nearly all adult rat tissues demonstrates that at least one CSPG is a constituent of most basement membranes, and by virtue of its unique distribution is distinct from other chondroitin and dermatan sulfate proteoglycans previously described.",
author = "McCarthy, {K J} and Couchman, {J R}",
note = "Keywords: Animals; Antibodies, Monoclonal; Basement Membrane; Female; Immunohistochemistry; Male; Microscopy, Electron; Proteochondroitin Sulfates; Proteoglycans; Rats; Rats, Inbred Strains",
year = "1990",
language = "English",
volume = "38",
pages = "1479--86",
journal = "Journal of Histochemistry and Cytochemistry",
issn = "0022-1554",
publisher = "SAGE Publications",
number = "10",

}

RIS

TY - JOUR

T1 - Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues.

AU - McCarthy, K J

AU - Couchman, J R

N1 - Keywords: Animals; Antibodies, Monoclonal; Basement Membrane; Female; Immunohistochemistry; Male; Microscopy, Electron; Proteochondroitin Sulfates; Proteoglycans; Rats; Rats, Inbred Strains

PY - 1990

Y1 - 1990

N2 - Heparan sulfate proteoglycans have been described as the major proteoglycan component of basement membranes. However, previous investigators have also provided evidence for the presence of chondroitin sulfate glycosaminoglycan in these structures. Recently we described the production and characterization of core protein-specific monoclonal antibodies (MAb) against a chondroitin sulfate proteoglycan (CSPG) present in Reichert's membrane, a transient extra-embryonic structure of rodents. This CSPG was also demonstrated to be present in adult rat kidney. We report here the tissue distribution of epitopes recognized by these MAb. The ubiquitous presence of these epitopes in the basement membranes of nearly all adult rat tissues demonstrates that at least one CSPG is a constituent of most basement membranes, and by virtue of its unique distribution is distinct from other chondroitin and dermatan sulfate proteoglycans previously described.

AB - Heparan sulfate proteoglycans have been described as the major proteoglycan component of basement membranes. However, previous investigators have also provided evidence for the presence of chondroitin sulfate glycosaminoglycan in these structures. Recently we described the production and characterization of core protein-specific monoclonal antibodies (MAb) against a chondroitin sulfate proteoglycan (CSPG) present in Reichert's membrane, a transient extra-embryonic structure of rodents. This CSPG was also demonstrated to be present in adult rat kidney. We report here the tissue distribution of epitopes recognized by these MAb. The ubiquitous presence of these epitopes in the basement membranes of nearly all adult rat tissues demonstrates that at least one CSPG is a constituent of most basement membranes, and by virtue of its unique distribution is distinct from other chondroitin and dermatan sulfate proteoglycans previously described.

M3 - Journal article

C2 - 2401786

VL - 38

SP - 1479

EP - 1486

JO - Journal of Histochemistry and Cytochemistry

JF - Journal of Histochemistry and Cytochemistry

SN - 0022-1554

IS - 10

ER -

ID: 5166634