Ying Liu

Ying Liu

Associate Professor - Promotion Programme


  1. 2002
  2. Published

    Physical and transcript map of the region between D6S264 and D6S149 on chromosome 6q27, the minimal region of allele loss in sporadic epithelial ovarian cancer

    Liu, Ying, Emilion, G., Mungall, A. J., Dunham, I., Beck, S., Le Meuth-Metzinger, V. G., Shelling, A. N., Charnock, F. M. L. & Ganesan, T. S., 17 Jan 2002, In: Oncogene. 21, 3, p. 387-99 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Tumour suppressor genes in sporadic epithelial ovarian cancer

    Liu, Ying & Ganesan, T. S., 1 Mar 2002, In: Reproduction. 123, 3, p. 341-53 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer

    Liu, Ying, Dodds, P., Emilion, G., Mungall, A. J., Dunham, I., Beck, S., Wells, R. S., Charnock, F. M. L. & Ganesan, T. S., 15 Oct 2002, In: B M C Genetics. 3, p. 20

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2004
  6. Published

    Carcinogenesis of Colorectal Cancer. In Cancer De Colon

    Liu, Ying & Bodmer, W., 2004, In: Reto E Anus. p. 43-54 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2005
  8. Published

    CDX1 is an important molecular mediator of Barrett's metaplasia

    Wong, N. A. C. S., Wilding, J., Bartlett, S., Liu, Ying, Warren, B. F., Piris, J., Maynard, N., Marshall, R. & Bodmer, W. F., 24 May 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 21, p. 7565-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2006
  10. Published

    Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines

    Liu, Ying & Bodmer, W. F., 24 Jan 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 4, p. 976-81 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers

    Gaasenbeek, M., Howarth, K., Rowan, A. J., Gorman, P. A., Jones, A., Chaplin, T., Liu, Ying, Bicknell, D., Davison, E. J., Fiegler, H., Carter, N. P., Roylance, R. R. & Tomlinson, I. P. M., 1 Apr 2006, In: Cancer Research. 66, 7, p. 3471-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2007
  13. Published

    RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer

    Bignone, P. A., Lee, K. Y., Liu, Ying, Emilion, G., Finch, J., Soosay, A. E. R., Charnock, F. M. L., Beck, S., Dunham, I., Mungall, A. J. & Ganesan, T. S., 1 Feb 2007, In: Oncogene. 26, 5, p. 683-700 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2009
  15. Published

    Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1

    Chan, C. W. M., Wong, N. A., Liu, Ying, Bicknell, D., Turley, H., Hollins, L., Miller, C. J., Wilding, J. L. & Bodmer, W. F., 10 Feb 2009, In: Proceedings of the National Academy of Sciences USA (PNAS). 106, 6, p. 1936-41 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mutations in the AXIN1 gene in advanced prostate cancer

    Yardy, G. W., Bicknell, D. C., Wilding, J. L., Bartlett, S., Liu, Ying, Winney, B., Turner, G. D. H., Brewster, S. F. & Bodmer, W. F., 1 Sep 2009, In: European Urology Supplements. 56, 3, p. 486-94 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2010
  18. Published

    5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency

    Bracht, K., Nicholls, A. M., Liu, Ying & Bodmer, W. F., 27 Jul 2010, In: British Journal of Cancer Management. 103, 3, p. 340-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Replication error deficient and proficient colorectal cancer gene expression differences caused by 3'UTR polyT sequence deletions

    Wilding, J. L., McGowan, S., Liu, Ying & Bodmer, W. F., 7 Dec 2010, In: PNAS Early Edition. 107, 49, p. 21058-63 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2013
  21. Published

    MUS81 promotes common fragile site expression

    Ying, S., Minocherhomji, S., Chan, K. L., Palmai-Pallag, T., Chu, W. K., Wass, T. A., Mankouri, H. W., Liu, Ying & Hickson, Ian David, Aug 2013, In: Nature Cell Biology. 15, 8, p. 1001-1007 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA

    Biebricher, A., Hirano, S., Enzlin, J., Wiechens, N., Streicher, W., Huttner, D., Wang, L., Nigg, E., Owen-Hughes, T., Liu, Ying, Peterman, E., Wuite, G. & Hickson, Ian David, 12 Sep 2013, In: Molecular Cell. 51, 5, p. 691-701 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells

    Simandlova, J., Zagelbaum, J., Payne, M. J., Chu, W. K., Shevelev, I., Hanada, K., Chatterjee, S., Reid, D. A., Liu, Ying, Janscak, P., Rothenberg, E. & Hickson, Ian David, 22 Nov 2013, In: The Journal of Biological Chemistry. 288, 47, p. 34168-80 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2014
  25. Published

    The origins and processing of ultra fine anaphase DNA bridges

    Liu, Ying, Nielsen, Christian Friberg, Yao, Q. & Hickson, Ian David, 30 Apr 2014, In: Current Opinion in Genetics & Development. 26C, p. 1-5 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. 2015
  27. Published

    Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

    Newman, J. A., Savitsky, P., Allerston, C. K., Bizard, A. H., Özer, Ö., Sarlós, K., Liu, Ying, Pardon, E., Steyaert, J., Hickson, Ian David & Gileadi, O., 2015, In: Nucleic Acids Research. 43, 10, p. 5221-35 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis

    Nielsen, Christian Friberg, Huttner, D., Bizard, A. H., Hirano, S., Li, T., Palmai-Pallag, T., Bjerregaard, Victoria Alexandra, Liu, Ying, Nigg, E. A., Wang, L. H. & Hickson, Ian David, 2015, In: Nature Communications. 6, 15 p., 8962.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress

    Bursomanno, S., McGouran, J. F., Kessler, B. M., Hickson, Ian David & Liu, Ying, 2015, In: Journal of Proteome Research. 14, 4, p. 1687-99 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells

    Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Hickson, Ian David & Liu, Ying, Jan 2015, In: DNA Repair. 25, p. 84-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Replication stress activates DNA repair synthesis in mitosis

    Minocherhomji, S., Ying, S., Bjerregaard, Victoria Alexandra, Bursomanno, S., Aleliunaite, A., Wu, Wei, Mankouri, H. W., Shen, H., Liu, Ying & Hickson, Ian David, 10 Dec 2015, In: Nature. 528, 7581, p. 286-90 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  32. 2016
  33. Published

    Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation

    Ghamrasni, S. E., Cardoso, R., Li, L., Guturi, K. K. N., Bjerregaard, Victoria Alexandra, Liu, Ying, Venkatesan, S., Hande, M. P., Henderson, J. T., Sanchez, O., Hickson, Ian David, Hakem, A. & Hakem, R., 15 Sep 2016, In: Oncogene. 35, 37, p. 4836-4845 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2017
  35. Published

    Biochemical and Mass Spectrometry-Based Approaches to Profile SUMOylation in Human Cells

    Kessler, B. M., Bursomanno, S., McGouran, J. F., Hickson, Ian David & Liu, Ying, 2017, Activity-Based Proteomics: Methods and Protocols. Overkleeft, H. S. & Florea, B. I. (eds.). Humana Press, Vol. 1491. p. 131-144 14 p. (Methods in Molecular Biology, Vol. 1491).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  36. Published

    Potential biomarkers of DNA replication stress in cancer

    Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2018
  38. Published

    Folate deficiency drives mitotic missegregation of the human FRAXA locus

    Bjerregaard, Victoria Alexandra, Garribba, L., McMurray, C. T., Hickson, Ian David & Liu, Ying, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. 13003-13008 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism

    Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Inducing and Detecting Mitotic DNA Synthesis at Difficult-to-Replicate Loci

    Garribba, L., Wu, Wei, Özer, Ö., Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2018, Methods in Enzymology: Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair. Spies, M. & Malkova, A. (eds.). Elsevier, Vol. 601. p. 45-58 14 p. (Methods in Enzymology; No. 601).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  41. Published

    The Detection and Analysis of Chromosome Fragile Sites

    Bjerregaard, Victoria Alexandra, Özer, Ö., Hickson, Ian David & Liu, Ying, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 471-482 12 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  42. 2019
  43. Published

    Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

    Pladevall Morera, David, Munk, S., Ingham, Andreas, Garribba, L., Albers, E., Liu, Ying, Olsen, Jesper Velgaard & Lopez-Contreras, Andres, 2019, In: Nucleic Acids Research. 47, 15, p. 8004-8018 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The RIF1-PP1 Axis Controls Abscission Timing in Human Cells

    Bhowmick, Rahul, Thakur, R. S., Venegas, A. B., Liu, Ying, Nilsson, Jakob, Barisic, Marin & Hickson, Ian David, 2019, In: Current Biology. 29, 7, p. 1232-1242.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2020
  46. Published

    Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells

    Garribba, L., Bjerregaard, Victoria Alexandra, Gonçalves Dinis, M. M., Özer, Ö., Wu, Wei, Sakellariou, D., Pena-Diaz, J., Hickson, Ian David & Liu, Ying, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16527-16536 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

    Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes

    Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells

    Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. 2021
  51. Published

    Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2

    Garribba, L., Vogel, Ivan, Lerdrup, Mads, Gonçalves Dinis, M. M., Ren, L. & Liu, Ying, 2021, In: Frontiers in Genetics. 12, 695124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 2022
  53. Published

    Nonlinear mechanics of human mitotic chromosomes

    Meijering, A. E. C., Sarlós, K., Nielsen, Christian Friberg, Witt, H., Harju, J., Kerklingh, E., Haasnoot, G. H., Bizard, A. H., Heller, I., Broedersz, C. P., Liu, Ying, Peterman, E. J. G., Hickson, Ian David & Wuite, G. J. L., 2022, In: Nature. p. 545–550

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    RAD51 protects human cells from transcription-replication conflicts

    Bhowmick, Rahul, Lerdrup, Mads, Gadi, Sampath Amitash, Rossetti, G. G., Singh, Manika Indrajit, Liu, Ying, Halazonetis, T. D. & Hickson, Ian David, 2022, In: Molecular Cell. 82, 18, p. 3366-3381.e9

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published
  56. 2023
  57. Published

    Completing genome replication outside of S phase

    Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2023, In: Molecular Cell. 83, 20, p. 3596-3607 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Mitotic DNA synthesis in response to replication stress requires the sequential action of DNA polymerases zeta and delta in human cells

    Wu, Wei, Barwacz, Szymon Aleksander, Bhowmick, Rahul, Lundgaard, Katrine, Gonçalves Dinis, M. M., Clausen, Malgorzata, Kanemaki, M. T. & Liu, Ying, 2023, In: Nature Communications. 14, 1, 706.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 22618792