Vilhelm Bohr

Vilhelm Bohr

Affiliate professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 3: Individualized health


  1. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif. / Andersen, Sofie Dabros; Keijzers, Guido; Rampakakis, Emmanouil; Engels, Kim; Luhn, Patricia; El-Shemerly, Mahmoud; Nielsen, Finn Cilius; Du, Yuhong; May, Alfred; Bohr, Vilhelm A; Ferrari, Stefano; Zannis-Hadjopoulos, Maria; Fu, Haian; Rasmussen, Lene Juel.

    In: D N A Repair, Vol. 11, No. 3, 03.2012, p. 267-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice. / Fang, Evandro F.; Palikaras, Konstantinos; Sun, Nuo; Fivenson, Elayne M.; Spangler, Ryan D.; Kerr, Jesse S.; Cordonnier, Stephanie A.; Hou, Yujun; Dombi, Eszter; Kassahun, Henok; Tavernarakis, Nektarios; Poulton, Joanna; Nilsen, Hilde; Bohr, Vilhelm A.

    In: Journal of Visualized Experiments, No. 129, e56301, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells. / Nguyen, Giang Huong; Dexheimer, Thomas S; Rosenthal, Andrew S; Chu, Wai Kit; Singh, Dharmendra Kumar; Mosedale, Georgina; Bachrati, Csanád Z; Schultz, Lena; Sakurai, Masaaki; Savitsky, Pavel; Abu, Mika; McHugh, Peter J; Bohr, Vilhelm A; Harris, Curtis C; Jadhav, Ajit; Gileadi, Opher; Maloney, David J; Simeonov, Anton; Hickson, Ian D.

    In: Chemistry & Biology, Vol. 20, No. 1, 24.01.2013, p. 55-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome. / Scheibye-Knudsen, Morten; Mitchell, Sarah J.; Fang, Evandro F.; Iyama, Teruaki; Ward, Theresa; Wang, James; Dunn, Christopher A.; Singh, Nagendra; Veith, Sebastian; Hasan-Olive, Md Mahdi; Mangerich, Aswin; Wilson, Mark A.; Mattson, Mark P.; Bergersen, Linda H.; Cogger, Victoria C.; Warren, Alessandra; Le Couteur, David G.; Moaddel, Ruin; Wilson, David M.; Croteau, Deborah L.; De Cabo, Rafael; Bohr, Vilhelm A.

    In: Cell Metabolism, Vol. 20, No. 5, 04.11.2014, p. 840-855.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. / Lauritzen, Knut H.; Hasan-Olive, Md Mahdi; Regnell, Christine E.; Kleppa, Liv; Scheibye-Knudsen, Morten; Gjedde, Albert; Klungland, Arne; Bohr, Vilhelm A.; Storm-Mathisen, Jon; Bergersen, Linda H.

    In: Neurobiology of Aging, Vol. 48, 12.2016, p. 34-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function. / Hey-Mogensen, Martin; Gram, Martin; Jensen, Martin Borch; Lund, Michael Taulo; Hansen, Christina Neigaard; Scheibye-Knudsen, Morten; Bohr, Vilhelm A.; Dela, Flemming.

    In: The Journal of Physiology, Vol. 593, No. 17, 01.09.2015, p. 3991-4010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. A research agenda for aging in China in the 21st century. / Fang, Evandro Fei; Scheibye-Knudsen, Morten; Jahn, Heiko J; Li, Juan; Ling, Li; Guo, Hongwei; Zhu, Xinqiang; Preedy, Victor; Lu, Huiming; Bohr, Vilhelm A; Chan, Wai Yee; Liu, Yuanli; Ng, Tzi Bun.

    In: Ageing Research Reviews, Vol. 24, No. Pt B, 11.2015, p. 197-205.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Acetylation regulates WRN catalytic activities and affects base excision DNA repair. / Muftuoglu, Meltem; Kusumoto, Rika; Speina, Elzbieta; Beck, Gad; Cheng, Wen-Hsing; Bohr, Vilhelm A.

    In: P L o S One, Vol. 3, No. 4, 01.2008, p. e1918.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover. / Nygaard, Rie Harboe; Maynard, Scott; Schjerling, Peter; Kjær, Michael; Qvortrup, Klaus; Bohr, Vilhelm A; Rasmussen, Lene J; Jemec, Gregor B E; Heidenheim, Michael.

    In: Case Reports in Dermatology, Vol. 8, No. 1, 14.06.2016, p. 42-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Aging, longevity and health. / Rasmussen, Lene Juel; Sander, Miriam; Wewer, Ulla M.; Bohr, Vilhelm A.

    In: Mechanisms of Ageing and Development, 23.07.2011, p. 522-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Aprataxin localizes to mitochondria and preserves mitochondrial function. / Sykora, Peter; Croteau, Deborah L; Bohr, Vilhelm A; Wilson, David M.

    In: Proceedings of the National Academy of Sciences USA (PNAS), Vol. 108, No. 18, 03.05.2011, p. 7437-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance. / Maynard, S; Keijzers, G; Hansen, Åse Marie; Osler, M; Molbo, D; Bendix, L; Møller, P; Loft, S; Moreno-Villanueva, M; Bürkle, A; Hvitby, Christina Poulsen; Schurman, S H; Stevnsner, Tinna V.; Rasmussen, L J; Avlund, K; Bohr, V A.

    In: Acta Physiologica (Print), Vol. 213, No. 1, 01.2015, p. 156-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Base excision repair activities differ in human lung cancer cells and corresponding normal controls. / Karahalil, Bensu; Bohr, Vilhelm A; De Souza-Pinto, Nadja C.

    In: Anticancer Research, Vol. 30, No. 12, 01.12.2010, p. 4963-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Base excision repair of oxidative DNA damage and association with cancer and aging. / Maynard, Scott; Schurman, Shepherd H; Harboe, Charlotte; de Souza-Pinto, Nadja C; Bohr, Vilhelm A.

    In: Carcinogenesis, Vol. 30, No. 1, 01.01.2009, p. 2-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks. / Liberti, Sascha E; Andersen, Sofie Dabros; Wang, Jing; May, Alfred; Miron, Simona; Perderiset, Mylene; Keijzers, Guido; Nielsen, Finn C; Charbonnier, Jean-Baptiste; Bohr, Vilhelm A; Rasmussen, Lene J.

    In: DNA Repair, Vol. 10, No. 1, 02.01.2011, p. 73-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Bohr på ny. / Bohr, Vilhelm; Bohr, Tomas; Topsøe, Haldor; Bruun, Lone ; Knudsen, Henrik; Nielsen, Henry ; Aaserud, Finn; Grandin, Karl; von Bülow, Hans; Kragh, Helge; Andersen, Anja C.; Mølmer, Klaus; Favrholdt, David; Faye, Jan; Zinkernagel, Henrik.

    København : Forlaget Epsilon.Dk, 2013.

    Research output: Book/ReportBookCommunication

  17. Published

    Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity. / Aamann, Maria Diget; Hvitby, Christina Poulsen; Popuri, Venkateswarlu; Muftuoglu, Meltem; Lemminger, Lasse Pagh Brøgger; Skeby, Cecilie K; Keijzers, Guido; Ahn, Byungchan; Bjørås, Magnar; Bohr, Vilhelm A; Stevnsner, Tinna V.

    In: Mechanisms of Ageing and Development, Vol. 135, 01.2014, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Cockayne syndrome : Clinical features, model systems and pathways. / Karikkineth, Ajoy C; Scheibye-Knudsen, Morten; Fivenson, Elayne; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Ageing Research Reviews, Vol. 33, 01.2017, p. 3-17.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA. / Scheibye-Knudsen, Morten; Tseng, Anne; Jensen, Martin Borch; Scheibye-Alsing, Karsten; Fang, Evandro Fei; Iyama, Teruaki; Bharti, Sanjay Kumar; Marosi, Krisztina; Froetscher, Lynn; Kassahun, Henok; Eckley, David Mark; Maul, Robert W.; Bastian, Paul; De, Supriyo; Ghosh, Soumita; Nilsen, Hilde; Goldberg, Ilya G.; Mattson, Mark P.; Wilson, David M., III; Brosh, Robert M., Jr.; Gorospe, Myriam; Bohr, Vilhelm A.

    In: National Academy of Sciences. Proceedings, Vol. 113, No. 44, 01.11.2016, p. 12502-12507.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. / Scheibye-Knudsen, Morten; Ramamoorthy, Mahesh; Sykora, Peter; Maynard, Scott; Lin, Ping-Chang; Minor, Robin K; Wilson, David M; Cooper, Marcus; Spencer, Richard; de Cabo, Rafael; Croteau, Deborah L; Bohr, Vilhelm A.

    In: The Journal of Experimental Medicine, Vol. 209, No. 4, 04.2012, p. 855-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane. / Aamann, Maria Diget; Sorensen, Martin M; Hvitby, Christina Poulsen; Berquist, Brian R; Muftuoglu, Meltem; Tian, Jingyan; de Souza-Pinto, Nadja C; Scheibye-Knudsen, Morten; Wilson, David M; Stevnsner, Tinna V.; Bohr, Vilhelm A.

    In: The FASEB Journal, Vol. 24, No. 7, 01.07.2010, p. 2334-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase. / Muftuoglu, Meltem; de Souza-Pinto, Nadja C; Dogan, Arin; Aamann, Maria; Stevnsner, Tinna; Rybanska, Ivana; Kirkali, Güldal; Dizdaroglu, Miral; Bohr, Vilhelm A.

    In: Journal of Biological Chemistry, Vol. 284, No. 14, 04.2009, p. 9270-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding. / Rossi, Marie L; Ghosh, Avik K; Kulikowicz, Tomasz; Croteau, Deborah L; Bohr, Vilhelm A.

    In: DNA Repair, Vol. 9, No. 7, 01.07.2010, p. 796-804.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders. / Scheibye-Knudsen, Morten; Fang, Evandro Fei; Croteau, Deborah L.; Bohr, Vilhelm A.

    In: Autophagy, Vol. 10, No. 8, 2014, p. 1468-1469.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops. / Kusumoto-Matsuo, Rika; Opresko, Patricia L; Ramsden, Dale; Tahara, Hidetoshi; Bohr, Vilhelm A.

    In: Aging, Vol. 2, No. 5, 01.05.2010, p. 274-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 4975983