Vilhelm Bohr

Vilhelm Bohr

Affiliate professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 3: Individualized health


  1. 2008
  2. Published

    Acetylation regulates WRN catalytic activities and affects base excision DNA repair. / Muftuoglu, Meltem; Kusumoto, Rika; Speina, Elzbieta; Beck, Gad; Cheng, Wen-Hsing; Bohr, Vilhelm A.

    In: P L o S One, Vol. 3, No. 4, 01.2008, p. e1918.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Human embryonic stem cells have enhanced repair of multiple forms of DNA damage. / Maynard, Scott; Swistowska, Anna Maria; Lee, Jae Wan; Liu, Ying; Liu, Su-Ting; Da Cruz, Alexandre Bettencourt; Rao, Mahendra; de Souza-Pinto, Nadja C; Zeng, Xianmin; Bohr, Vilhelm A.

    In: Stem Cells, Vol. 26, No. 9, 01.09.2008, p. 2266-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2009
  5. Published

    Base excision repair of oxidative DNA damage and association with cancer and aging. / Maynard, Scott; Schurman, Shepherd H; Harboe, Charlotte; de Souza-Pinto, Nadja C; Bohr, Vilhelm A.

    In: Carcinogenesis, Vol. 30, No. 1, 01.01.2009, p. 2-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. / McCord, Ronald A; Michishita, Eriko; Hong, Tao; Berber, Elisabeth; Boxer, Lisa D; Kusumoto, Rika; Guan, Shenheng; Shi, Xiaobing; Gozani, Or; Burlingame, Alma L; Bohr, Vilhelm A; Chua, Katrin F.

    In: Aging, Vol. 1, No. 1, 01.01.2009, p. 109-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase. / Muftuoglu, Meltem; de Souza-Pinto, Nadja C; Dogan, Arin; Aamann, Maria; Stevnsner, Tinna; Rybanska, Ivana; Kirkali, Güldal; Dizdaroglu, Miral; Bohr, Vilhelm A.

    In: Journal of Biological Chemistry, Vol. 284, No. 14, 04.2009, p. 9270-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells. / de Souza-Pinto, Nadja C; Maynard, Scott; Hashiguchi, Kazunari; Hu, Jingping; Muftuoglu, Meltem; Bohr, Vilhelm A.

    In: Molecular and Cellular Biology, Vol. 29, No. 16, 08.2009, p. 4441-54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2010
  10. Published

    Mitochondrial helicases and mitochondrial genome maintenance. / de Souza-Pinto, Nadja C; Aamann, Maria Diget; Kulikowicz, Tomasz; Stevnsner, Tinna V.; Bohr, Vilhelm A.

    In: Mechanisms of Ageing and Development, Vol. 131, No. 7-8, 2010, p. 503-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1. / Yang, Jenq-Lin; Tadokoro, Takashi; Keijzers, Guido; Mattson, Mark P; Bohr, Vilhelm.

    In: Journal of Biological Chemistry, Vol. 285, No. 36, 2010, p. 28191-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Earl R. Stadtman. / Levine, Rodney L; Bohr, Vilhelm A.

    In: Mechanisms of Ageing and Development, Vol. 131, No. 1, 01.01.2010, p. 1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Impact papers on aging in 2009. / Blagosklonny, Mikhail V; Campisi, Judy; Sinclair, David A; Bartke, Andrzej; Blasco, Maria A; Bonner, William M; Bohr, Vilhelm A; Brosh, Robert M; Brunet, Anne; Depinho, Ronald A; Donehower, Lawrence A; Finch, Caleb E; Finkel, Toren; Gorospe, Myriam; Gudkov, Andrei V; Hall, Michael N; Hekimi, Siegfried; Helfand, Stephen L; Karlseder, Jan; Kenyon, Cynthia; Kroemer, Guido; Longo, Valter; Nussenzweig, Andre; Osiewacz, Heinz D; Peeper, Daniel S; Rando, Thomas A; Rudolph, K Lenhard; Sassone-Corsi, Paolo; Serrano, Manuel; Sharpless, Norman E; Skulachev, Vladimir P; Tilly, Jonathan L; Tower, John; Verdin, Eric; Vijg, Jan.

    In: Aging, Vol. 2, No. 3, 01.03.2010, p. 111-21.

    Research output: Contribution to journalReviewResearch

  14. Published

    Roles of Werner syndrome protein in protection of genome integrity. / Rossi, Marie L; Ghosh, Avik K; Bohr, Vilhelm A.

    In: DNA Repair, Vol. 9, No. 3, 02.03.2010, p. 331-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms. / Massip, L; Garand, C; Labbé, A; Perreault, E; Turaga, R V N; Bohr, V A; Lebel, M.

    In: Oncogene, Vol. 29, No. 10, 11.03.2010, p. 1486-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Nutrition and aging. / Cheng, Wen-Hsing; Bohr, Vilhelm A; de Cabo, Rafael.

    In: Mechanisms of Ageing and Development, Vol. 131, No. 4, 01.04.2010, p. 223-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops. / Kusumoto-Matsuo, Rika; Opresko, Patricia L; Ramsden, Dale; Tahara, Hidetoshi; Bohr, Vilhelm A.

    In: Aging, Vol. 2, No. 5, 01.05.2010, p. 274-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Human RECQL5beta stimulates flap endonuclease 1. / Speina, Elzbieta; Dawut, Lale; Hedayati, Mohammad; Wang, Zhengming; May, Alfred; Schwendener, Sybille; Janscak, Pavel; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Nucleic Acids Symposium Series, Vol. 38, No. 9, 01.05.2010, p. 2904-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The involvement of human RECQL4 in DNA double-strand break repair. / Singh, Dharmendra Kumar; Karmakar, Parimal; Aamann, Maria Diget; Schurman, Shepherd H; May, Alfred; Croteau, Deborah L; Burks, Lynnette; Plon, Sharon E; Bohr, Vilhelm A.

    In: Aging Cell, Vol. 9, No. 3, 01.06.2010, p. 358-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases. / Popuri, Venkateswarlu; Croteau, Deborah L; Bohr, Vilhelm A.

    In: DNA Repair, Vol. 9, No. 6, 04.06.2010, p. 636-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Mitochondria and aging. / Prolla, Tomas A; Bohr, Vilhelm A; de Souza-Pinto, Nadja C.

    In: Mechanisms of Ageing and Development, Vol. 131, No. 7-8, 07.2010, p. 449-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane. / Aamann, Maria Diget; Sorensen, Martin M; Hvitby, Christina Poulsen; Berquist, Brian R; Muftuoglu, Meltem; Tian, Jingyan; de Souza-Pinto, Nadja C; Scheibye-Knudsen, Morten; Wilson, David M; Stevnsner, Tinna V.; Bohr, Vilhelm A.

    In: The FASEB Journal, Vol. 24, No. 7, 01.07.2010, p. 2334-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding. / Rossi, Marie L; Ghosh, Avik K; Kulikowicz, Tomasz; Croteau, Deborah L; Bohr, Vilhelm A.

    In: DNA Repair, Vol. 9, No. 7, 01.07.2010, p. 796-804.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population. / Berquist, Brian R; Singh, Dharmendra Kumar; Fan, Jinshui; Kim, Daemyung; Gillenwater, Elizabeth; Kulkarni, Avanti; Bohr, Vilhelm A; Ackerman, Eric J; Tomkinson, Alan E; Wilson, David M.

    In: Nucleic Acids Symposium Series, Vol. 38, No. 15, 01.08.2010, p. 5023-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Mitochondrial DNA repair and association with aging--an update. / Diaz, Ricardo Gredilla; Bohr, Vilhelm A; Stevnsner, Tinna V.

    In: Experimental Gerontology, Vol. 45, No. 7-8, 01.08.2010, p. 478-88.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Mitochondrial base excision repair assays. / Maynard, Scott; de Souza-Pinto, Nadja C; Scheibye-Knudsen, Morten; Bohr, Vilhelm A.

    In: Methods, Vol. 51, No. 4, 01.08.2010, p. 416-25.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease. / Diaz, Ricardo Gredilla; Weissman, Lior; Yang, Jenq-Lin; Bohr, Vilhelm A; Stevnsner, Tinna V.

    In: Neurobiology of Aging, 12.08.2010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Telomerer--begyndelsen og enden. / Bohr, Vilhelm A.

    In: Ugeskrift for Laeger, Vol. 172, No. 40, 04.10.2010, p. 2744.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The mitochondrial transcription factor A functions in mitochondrial base excision repair. / Canugovi, Chandrika; Maynard, Scott; Bayne, Anne-Cécile V; Sykora, Peter; Tian, Jingyan; de Souza-Pinto, Nadja C; Croteau, Deborah L; Bohr, Vilhelm A.

    In: DNA Repair, Vol. 9, No. 10, 05.10.2010, p. 1080-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Human RecQL4 helicase plays critical roles in prostate carcinogenesis. / Su, Yanrong; Meador, Jarah A; Calaf, Gloria M; Proietti De-Santis, Luca; Zhao, Yongliang; Bohr, Vilhelm A; Balajee, Adayabalam S.

    In: Cancer Research, Vol. 70, No. 22, 15.11.2010, p. 9207-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    DNA Repair and the Accumulation of Oxidatively Damaged DNA Are Affected by Fruit Intake in Mice. / Croteau, Deborah L; de Souza-Pinto, Nadja C; Harboe, Charlotte; Keijzers, Guido; Zhang, Yongqing; Becker, Kevin; Sheng, Shan; Bohr, Vilhelm.

    In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, Vol. 65, No. 12, 12.2010, p. 1300-1311.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Base excision repair activities differ in human lung cancer cells and corresponding normal controls. / Karahalil, Bensu; Bohr, Vilhelm A; De Souza-Pinto, Nadja C.

    In: Anticancer Research, Vol. 30, No. 12, 01.12.2010, p. 4963-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data. / Soerensen, Mette; Dato, Serena; Christensen, Kaare; McGue, Matt; Stevnsner, Tinna V.; Bohr, Vilhelm A; Christiansen, Lene.

    In: Aging Cell, Vol. 9, No. 6, 01.12.2010, p. 1010-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2011
  35. Published

    Metabolism, genomics, and DNA repair in the mouse aging liver. / Lebel, Michel; de Souza-Pinto, Nadja C; Bohr, Vilhelm A.

    In: Current Gerontology and Geriatrics Research, Vol. 2011, 01.01.2011, p. 859415.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks. / Liberti, Sascha E; Andersen, Sofie Dabros; Wang, Jing; May, Alfred; Miron, Simona; Perderiset, Mylene; Keijzers, Guido; Nielsen, Finn C; Charbonnier, Jean-Baptiste; Bohr, Vilhelm A; Rasmussen, Lene J.

    In: DNA Repair, Vol. 10, No. 1, 02.01.2011, p. 73-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1. / Rhee, David B; Ghosh, Avik; Lu, Jian; Bohr, Vilhelm A; Liu, Yie.

    In: DNA Repair, Vol. 10, No. 1, 02.01.2011, p. 34-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions. / Liu, Dong; Croteau, Deborah L; Souza-Pinto, Nadja; Pitta, Michael; Tian, Jingyan; Wu, Christopher; Jiang, Haiyang; Mustafa, Khadija; Keijzers, Guido; Bohr, Vilhelm; Mattson, Mark P.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 31, No. 2, 02.2011, p. 680-692.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples. / Lachapelle, Sophie; Gagné, Jean-Philippe; Garand, Chantal; Desbiens, Myriam; Coulombe, Yan; Bohr, Vilhelm A; Hendzel, Michael J; Masson, Jean-Yves; Poirier, Guy G; Lebel, Michel.

    In: Journal of Proteome Research, Vol. 10, No. 3, 04.03.2011, p. 1216-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells. / Bacolla, Albino; Wang, Guliang; Jain, Aklank; Chuzhanova, Nadia A; Cer, Regina Z; Collins, Jack R; Cooper, David N; Bohr, Vilhelm A; Vasquez, Karen M.

    In: The Journal of Biological Chemistry, Vol. 286, No. 12, 25.03.2011, p. 10017-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    DNA repair deficiency in neurodegeneration. / Jeppesen, Dennis Kjølhede; Bohr, Vilhelm A; Stevnsner, Tinna V.

    In: Progress in Neurobiology, Vol. 94, No. 2, 30.04.2011, p. 166-200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Aprataxin localizes to mitochondria and preserves mitochondrial function. / Sykora, Peter; Croteau, Deborah L; Bohr, Vilhelm A; Wilson, David M.

    In: Proceedings of the National Academy of Sciences USA (PNAS), Vol. 108, No. 18, 03.05.2011, p. 7437-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein. / Bernier, Michel; Paul, Rajib K; Martin-Montalvo, Alejandro; Scheibye-Knudsen, Morten; Song, Shaoming; He, Hua-Jun; Armour, Sean M; Hubbard, Basil P; Bohr, Vilhelm A; Wang, Lili; Zong, Yaping; Sinclair, David A; de Cabo, Rafael.

    In: The Journal of Biological Chemistry, Vol. 286, No. 22, 03.06.2011, p. 19270-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Aging, longevity and health. / Rasmussen, Lene Juel; Sander, Miriam; Wewer, Ulla M.; Bohr, Vilhelm A.

    In: Mechanisms of Ageing and Development, 23.07.2011, p. 522-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2012
  46. Published

    RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity. / Croteau, Deborah L; Rossi, Marie L; Canugovi, Chandrika; Tian, Jane; Sykora, Peter; Ramamoorthy, Mahesh; Wang, Zheng Ming; Singh, Dharmendra Kumar; Akbari, Mansour; Kasiviswanathan, Rajesh; Copeland, William C; Bohr, Vilhelm A.

    In: Aging Cell, Vol. 11, No. 3, 2012, p. 456-66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif. / Andersen, Sofie Dabros; Keijzers, Guido; Rampakakis, Emmanouil; Engels, Kim; Luhn, Patricia; El-Shemerly, Mahmoud; Nielsen, Finn Cilius; Du, Yuhong; May, Alfred; Bohr, Vilhelm A; Ferrari, Stefano; Zannis-Hadjopoulos, Maria; Fu, Haian; Rasmussen, Lene Juel.

    In: D N A Repair, Vol. 11, No. 3, 03.2012, p. 267-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. / Scheibye-Knudsen, Morten; Ramamoorthy, Mahesh; Sykora, Peter; Maynard, Scott; Lin, Ping-Chang; Minor, Robin K; Wilson, David M; Cooper, Marcus; Spencer, Richard; de Cabo, Rafael; Croteau, Deborah L; Bohr, Vilhelm A.

    In: The Journal of Experimental Medicine, Vol. 209, No. 4, 04.2012, p. 855-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients. / Jensen, Martin Borch; Dunn, Christopher A; Keijzers, Guido; Kulikowicz, Tomasz; Rasmussen, Lene Juel; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Aging, Vol. 4, No. 11, 11.2012, p. 790-802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2013
  51. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells. / Nguyen, Giang Huong; Dexheimer, Thomas S; Rosenthal, Andrew S; Chu, Wai Kit; Singh, Dharmendra Kumar; Mosedale, Georgina; Bachrati, Csanád Z; Schultz, Lena; Sakurai, Masaaki; Savitsky, Pavel; Abu, Mika; McHugh, Peter J; Bohr, Vilhelm A; Harris, Curtis C; Jadhav, Ajit; Gileadi, Opher; Maloney, David J; Simeonov, Anton; Hickson, Ian D.

    In: Chemistry & Biology, Vol. 20, No. 1, 24.01.2013, p. 55-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Bohr på ny. / Bohr, Vilhelm; Bohr, Tomas; Topsøe, Haldor; Bruun, Lone ; Knudsen, Henrik; Nielsen, Henry ; Aaserud, Finn; Grandin, Karl; von Bülow, Hans; Kragh, Helge; Andersen, Anja C.; Mølmer, Klaus; Favrholdt, David; Faye, Jan; Zinkernagel, Henrik.

    København : Forlaget Epsilon.Dk, 2013.

    Research output: Book/ReportBookCommunication

  53. Published

    Modulation of DNA base excision repair during neuronal differentiation. / Sykora, Peter; Yang, Jenq-Lin; Ferrarelli, Leslie K; Tian, Jingyan; Tadokoro, Takashi; Kulkarni, Avanti; Weissman, Lior; Keijzers, Guido; Wilson, David M; Mattson, Mark P; Bohr, Vilhelm A.

    In: Neurobiology of Aging, Vol. 34, No. 7, 07.2013, p. 1717-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    DNA damage response, bioenergetics, and neurological disease : the challenge of maintaining brain health in an aging human population. / Rasmussen, Lene Juel; Shiloh, Yosef; Bergersen, Linda H; Sander, Miriam; Bohr, Vilhelm A; Tønjum, Tone.

    In: Mechanisms of Ageing and Development, Vol. 134, No. 10, 10.2013, p. 427-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells. / Maynard, Scott; Keijzers, Guido; Gram, Martin; Madsen, Claus Desler; Bendix, Laila; Budtz-Jørgensen, Esben; Molbo, Drude; Croteau, Deborah L; Osler, Merete; Stevnsner, Tinna V.; Rasmussen, Lene Juel; Dela, Flemming; Avlund, Kirsten; Bohr, Vilhelm A.

    In: Aging, 30.11.2013, p. 850-864.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2014
  57. Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders. / Scheibye-Knudsen, Morten; Fang, Evandro Fei; Croteau, Deborah L.; Bohr, Vilhelm A.

    In: Autophagy, Vol. 10, No. 8, 2014, p. 1468-1469.

    Research output: Contribution to journalJournal articleResearchpeer-review

Previous 1 2 Next

ID: 4975983