Steen Larsen

Steen Larsen

Associate Professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 3: Individualized health


  1. 2019
  2. Published

    Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity. / Dall, Morten; Trammell, Samuel A J; Asping, Magnus; Hassing, Anna S; Agerholm, Marianne; Vienberg, Sara G; Gillum, Matthew P; Larsen, Steen; Treebak, Jonas T.

    In: The Journal of Biological Chemistry, Vol. 294, No. 36, 06.09.2019, p. 13304-13326.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Statin Treatment Decreases Mitochondrial Respiration But Muscle Coenzyme Q10 Levels Are Unaltered : The LIFESTAT Study. / Dohlmann, Tine Lovsø; Morville, Thomas; Kuhlman, Anja Birk; Chrøis, Karoline Maise; Helge, Jørn Wulff; Dela, Flemming; Larsen, Steen.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 104, No. 7, 07.2019, p. 2501–2508.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations. / Graae, Anne-Sofie; Grarup, Niels; Ribel-Madsen, Rasmus; Lystbæk, Sara Hyldegaard; Boesgaard, Trine; Staiger, Harald; Fritsche, Andreas; Wellner, Niels; Sulek, Karolina; Kjølby, Mads Fuglsang; Backe, Marie Balslev; Chubanava, Sabina; Prats, Clara; Serup, Annette Karen Lundbeck; Birk, Jesper Bratz; Dubail, Johanne; Gillberg, Linn; Vienberg, Sara Gry; Nykjær, Anders; Kiens, Bente; Wojtaszewski, Jørgen; Larsen, Steen; Apte, Suneel S; Häring, Hans-Ulrich; Vaag, Allan; Zethelius, Björn; Pedersen, Oluf Borbye; Treebak, Jonas Thue; Hansen, Torben; Holst, Birgitte.

    In: Diabetes, Vol. 68, No. 3, 2019, p. 502-514.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study. / Morville, Thomas; Dohlmann, Tine Lovso; Kuhlman, Anja Birk; Sahl, Ronni Eg; Kriegbaum, Margit; Larsen, Steen; Dela, Flemming; Helge, Jorn Wulff.

    In: Medicine and Science in Sports and Exercise, Vol. 51, No. 7, 2019, p. 1429-1437.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Aerobic and resistance exercise training reverses age-dependent decline in NAD(+) salvage capacity in human skeletal muscle. / de Guia, Roldan M.; Agerholm, Marianne; Nielsen, Thomas S.; Consitt, Leslie A.; Sogaard, Ditte; Helge, Jorn W.; Larsen, Steen; Brandauer, Josef; Houmard, Joseph A.; Treebak, Jonas T.

    In: Physiological Reports, Vol. 7, No. 12, e14139, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Clusters of Glycemic Response to Oral Glucose Tolerance Tests Explain Multivariate Metabolic and Anthropometric Outcomes of Bariatric Surgery in Obese Patients. / Szczerbinski, Lukasz; Taylor, Mark A.; Citko, Anna; Gorska, Maria; Larsen, Steen; Hady, Hady Razak; Kretowski, Adam.

    In: Journal of Clinical Medicine, Vol. 8, No. 8, 1091, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. E-pub ahead of print

    Determination and validation of peak fat oxidation in endurance-trained men using an upper body graded exercise test. / Hansen, Mikkel Thunestvedt; Romer, Tue; Frandsen, Jacob; Larsen, Steen; Dela, Flemming; Helge, Jorn Wulff.

    In: Scandinavian Journal of Medicine & Science in Sports, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes. / Dela, Flemming; Ingersen, Arthur; Andersen, Nynne Bjerre; Nielsen, Maria Booth; Petersen, Helga Huld Halldórsdóttir; Hansen, Christina Neigaard; Larsen, Steen; Wojtaszewski, Jørgen; Helge, Jørn Wulff.

    In: Acta Physiologica (Print), Vol. 226, No. 2, e13245, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Glucose homeostasis in statin users-The LIFESTAT study. / Morville, Thomas; Dohlmann, Tine; Kuhlman, Anja B.; Monberg, Tine; Torp, Mimmi; Hartmann, Bolette; Holst, Jens J.; Larsen, Steen; Helge, Jørn W.; Dela, Flemming.

    In: Diabetes - Metabolism: Research and Reviews (Print Edition), Vol. 35, No. 3, e3110, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glucose metabolism dysregulation affects the transcriptome of skeletal muscle and responds to three-month exercise intervention in humans. / Szczerbinski, L.; Niemira, M.; Szczerbinski, K.; Puchta, U.; Taylor, M.; Citko, A.; Siewiec, E.; Zapolska, J.; Larsen, S.; Gorska, M.; Kretowski, A.

    In: Diabetologia, Vol. 62, No. Supl. 1/SI, 127, 2019, p. S66-S66.

    Research output: Contribution to journalConference articleResearch

  12. Published

    Influence of exercise amount and intensity on long-term weight loss maintenance and skeletal muscle mitochondrial ROS production in humans. / Larsen, Steen; Dandanell, Sune; Kristensen, Kasper Birch; Jorgensen, Sofie Drevsholt; Dela, Flemming; Helge, Jorn W.

    In: Applied Physiology, Nutrition and Metabolism, Vol. 44, No. 9, 2019, p. 958-964.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. E-pub ahead of print

    Mitochondrial adaptations to high intensity interval training in older females and males. / Chrois, Karoline Maise; Dohlmann, Tine Lovso; Sogaard, Ditte; Hansen, Camilla Vestergaard; Dela, Flemming; Helge, Jorn Wulff; Larsen, Steen.

    In: European Journal of Sport Science, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training. / Søgaard, Ditte; Baranowski, Marcin; Larsen, Steen; Taulo Lund, Michael; Munk Scheuer, Cathrine; Vestergaard Abildskov, Carina; Greve Dideriksen, Sofie; Dela, Flemming; Wulff Helge, Jørn.

    In: International Journal of Molecular Sciences, Vol. 20, No. 5, 1240, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Plasma free fatty acid concentration is closely tied to whole-body peak fat oxidation rate during repeated exercise. / Frandsen, Jacob; Vest, Stine Dahl; Ritz, Christian; Larsen, Steen; Dela, Flemming; Helge, Jørn Wulff.

    In: Journal of Applied Physiology, Vol. 126, No. 6, 2019, p. 1563-1571.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2018
  17. Published

    Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies. / Sahl, Ronni Eg; Morville, Thomas; Kraunsøe, Regitze; Dela, Flemming; Helge, Jørn Wulff; Larsen, Steen.

    In: Analytical Biochemistry, Vol. 556, 01.09.2018, p. 119-124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery. / Lund, M. T.; Larsen, S.; Hansen, M.; Courraud, J.; Floyd, A. K.; Støckel, M.; Helge, J. W.; Dela, F.

    In: Acta Physiologica, Vol. 223, No. 1, e13032, 01.05.2018, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    High-intensity interval training improves insulin sensitivity in older individuals. / Søgaard, D; Lund, M T; Scheuer, C M; Dehlbaek, M S; Dideriksen, S G; Abildskov, C V; Christensen, K K; Dohlmann, T L; Larsen, S; Vigelsø, A H; Dela, F; Helge, J W.

    In: Acta Physiologica (Print), Vol. 222, No. 4, e13009, 04.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis. / Lundby, Anne-Kristine Meinild; Jacobs, R A; Gehrig, S; de Leur, J; Hauser, M; Bonne, Thomas Christian; Flück, Daniela; Dandanell, Sune; Kirk, N; Kaech, A; Ziegler, U; Larsen, Steen; Lundby, Carsten.

    In: Acta Physiologica (Print), Vol. 222, No. 1, e12905, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males. / Larsen, Steen; Lundby, Anne-Kristine M; Dandanell, Sune; Oberholzer, Laura; Keiser, Stefanie; Andersen, Andreas Breenfeldt; Haider, Thomas; Lundby, Carsten.

    In: Physiological Reports, Vol. 6, No. 18, e13793, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle. / Andersen, Marianne Agerholm; Dall, Morten; Jensen, Benjamin Anderschou Holbech; Prats, Clara; Madsen, Søren; Basse, Astrid Linde; Graae, Anne-Sofie; Risis, Steve; Goldenbaum, Julie; Quistorff, Bjørn; Larsen, Steen; Vienberg, Sara Gry; Treebak, Jonas Thue.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 314, No. 4, 2018, p. E377-E395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2017
  24. Published

    Influence of maximal fat oxidation on long-term weight loss maintenance in humans. / Dandanell, Sune; Husted, Karina; Amdisen, Signe; Vigelso, Andreas; Dela, Flemming; Larsen, Steen; Helge, Jorn Wulff.

    In: Journal of Applied Physiology, Vol. 123, No. 1, 07.2017, p. 267-274.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Is there plasticity in mitochondrial cristae density with endurance training? / Larsen, Steen; Helge, Jorn W.; Dela, Flemming.

    In: Journal of Physiology, Vol. 595, No. 9, 01.05.2017, p. 2985-2985.

    Research output: Contribution to journalComment/debateResearchpeer-review

  26. Published

    Determination of the exercise intensity that elicits maximal fat oxidation in individuals with obesity. / Jørgensen, Sune Dandanell; Præst, Charlotte Boslev; Søndergård, Stine Dam; Skovborg, Camilla; Dela, Flemming; Larsen, Steen; Helge, Jørn Wulff.

    In: Applied Physiology, Nutrition and Metabolism, Vol. 42, No. 4, 04.2017, p. 405-412.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2016
  28. Published

    Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle. / Søndergård, Stine D; Dela, Flemming; Helge, Jørn W; Larsen, Steen.

    In: European Journal of Sport Science, Vol. 16, No. 7, 10.2016, p. 801-807.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Effect of regional muscle location but not adiposity on mitochondrial biogenesis-regulating proteins. / Ponce-González, Jesús Gustavo; Ara, Ignacio; Larsen, Steen; Guerra, Borja; Calbet, Jose A L; Helge, Jørn Wulff.

    In: European Journal of Applied Physiology, Vol. 116, No. 1, 01.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published
  31. 2015
  32. Published

    The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue. / Larsen, Steen; Danielsen, J H; Søndergård, Stine Dam; Søgaard, D; Vigelsoe, A; Dybboe, R; Skaaby, S; Dela, F; Helge, J W.

    In: Scandinavian Journal of Medicine & Science in Sports, Vol. 25, No. 1, 02.2015, p. e59-e69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia. / Larsen, Steen; Scheede-Bergdahl, Celena; Whitesell, Thomas; Boushel, Robert; Bergdahl, Andreas.

    In: Physiological Reports, Vol. 3, No. 7, e12467, 2015, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2014
  35. Published

    A maximal cycle test with good validity and high repeatability in adults of all ages. / Eriksen, L; Tolstrup, J S; Larsen, Steen; Grønbæk, M; Helge, Jørn Wulff.

    In: International Journal of Sports Medicine, Vol. 35, No. 14, 12.2014, p. 1184-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Effects of exercise training on mitochondrial function in patients with type 2 diabetes. / Larsen, Steen; Skaaby, Stinna; Helge, Jørn Wulff; Dela, Flemming.

    In: World Journal of Diabetes, Vol. 5, No. 4, 15.08.2014, p. 482-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cardiac, Skeletal, and smooth muscle mitochondrial respiration : Are all mitochondria created equal? / Park, Song-Young; Gifford, Jayson R; Andtbacka, Robert H I; Hyngstrom, John R; Garten, Ryan S; Diakos, Nikolaos A; Ives, Stephen J; Dela, Flemming; Larsen, Steen; Drakos, Stavros; Richardson, Russell S.

    In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 307, No. 3, 06.06.2014, p. H346-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Influence of age on leptin induced skeletal muscle signaling. / Guadalupe Grau, Amelia; Larsen, Steen; Guerra, Borja; Calbet, Jose Al; Dela, Flemming; Helge, Jørn Wulff.

    In: Acta Physiologica, Vol. 211, No. 1, 08.03.2014, p. 214-228.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Increased intrinsic mitochondrial function in humans with mitochondrial haplogroup H. / Larsen, Steen; Díez-Sánchez, Carmen; Rabøl, Rasmus; Ara, Ignacio; Dela, Flemming; Helge, Jørn Wulff.

    In: Biochimica et Biophysica Acta - Bioenergetics, Vol. 1837, No. 2, 02.2014, p. 226-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2013
  41. Published

    Reply. / Larsen, Steen; Hansen, Christina N; Helge, Jørn Wulff; Dela, Flemming.

    In: Journal of the American College of Cardiology, Vol. 62, No. 3, 16.07.2013, p. 257-8.

    Research output: Contribution to journalComment/debateResearchpeer-review

  42. Published

    Reply. / Larsen, Steen; Stride, Nis; Hey-Mogensen, Martin; Hansen, Christina N; Bang, Lia E; Bundgaard, Henning; Nielsen, Lars B; Helge, Jørn Wulff; Dela, Flemming.

    In: Journal of the American College of Cardiology, Vol. 61, No. 23, 11.06.2013, p. 2393.

    Research output: Contribution to journalComment/debateResearchpeer-review

  43. Published

    Impaired mitochondrial function in chronically ischemic human heart. / Stride, Nis; Larsen, Steen; Hey-Mogensen, Martin; Hansen, Christina N; Prats Gavalda, Clara; Steinbrüchel, Daniel; Køber, Lars; Dela, Flemming.

    In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 304, No. 11, 01.06.2013, p. H1407-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Impaired mitochondrial function in chronically ischemic human heart. / Stride, Nis Ottesen; Larsen, Steen; Hey-Mogensen, Martin; Hansen, Christina; Prats, Clara; Steinbrüchel, Daniel; Køber, Lars; Dela, Flemming.

    In: A J P: Heart and Circulatory Physiology (Online), Vol. 304, No. 11, 2013, p. H1407-H1414.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published
  46. Published
  47. 2012
  48. Published

    Ceramide content is higher in type I compared to type II fibers in obesity and type 2 diabetes mellitus. / Kristensen, Ditte Bech; Prats Gavalda, Clara; Larsen, Steen; Ara, Ignacio; Dela, Flemming; Helge, Jørn W; Larsen, Steen.

    In: Acta Diabetologica, 2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Cryopreservation of human skeletal muscle impairs mitochondrial function. / Larsen, Steen; Wright-Paradis, C; Gnaiger, E; Helge, Jørn Wulff; Boushel, R.

    In: Cryo-Letters, Vol. 33, No. 3, 2012, p. 169-175.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration. / Larsen, Steen; Rabøl, R; Hansen, C N; Madsbad, S; Helge, J W; Dela, F.

    In: Diabetologia, Vol. 55, No. 2, 2012, p. 443-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    The influence of age and aerobic fitness : effects on mitochondrial respiration in skeletal muscle. / Hey-Mogensen, M; Rabøl, R; Stride, N; Helge, J W; Dela, F; Larsen, Steen.

    In: Acta Physiologica (Print), Vol. 205, No. 3, 2012, p. 423-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 2011
  53. Published

    Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes. / Larsen, S; Stride, N; Hey-Mogensen, Martin; Hansen, C N; Andersen, J L; Madsbad, S; Worm, D; Helge, J W; Dela, F.

    In: Diabetologia, Vol. 54, No. 6, 2011, p. 1427-36.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Normal mitochondrial function and increased fat oxidation capacity in leg and arm muscles in obese humans. / Ara, I; Larsen, S; Stallknecht, Bente Merete; Guerra, B; Morales-Alamo, D; Andersen, J L; Ponce-González, J G; Guadalupe-Grau, A; Galbo, H; Calbet, J A L; Helge, J W.

    In: International Journal of Obesity, Vol. 35, No. 1, 2011, p. 99-108.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2010
  56. Published

    Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity. / Rabøl, R; Larsen, S; Højberg, P M V; Almdal, T; Boushel, Robert Christopher; Haugaard, S B; Andersen, J L; Madsbad, S; Dela, F.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 95, No. 2, 01.02.2010, p. 857-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2009
  58. Published

    Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes? / Larsen, Steen; Ara, I; Rabøl, R; Andersen, J L; Boushel, R; Dela, F; Helge, J W.

    In: Diabetologia, Vol. 52, No. 7, 2009, p. 1400-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. 2004
  60. Published

    Alcohol modulates circulating levels of interleukin-6 and monocyte chemoattractant protein-1 in chronic pancreatitis. / Pedersen, N; Larsen, S; Seidelin, J B; Nielsen, O H.

    In: Scandinavian Journal of Gastroenterology, Vol. 39, No. 3, 03.2004, p. 277-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4969436