Simon Holst Bekker-Jensen

Simon Holst Bekker-Jensen

Professor

Member of:


  1. 2024
  2. Published

    Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L

    Xi, J., Snieckute, Goda, Martínez Hernández, José Francisco, Arendrup, Frederic Schrøder, Asthana, A., Gaughan, C., Lund, Anders H., Bekker-Jensen, Simon Holst & Silverman, R. H., 2024, In: Cell Reports. 43, 4, 20 p., 113998.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Mechanisms underlying sensing of cellular stress signals by mammalian MAP3 kinases

    Mordente, Kelly Christine, Jordan, Laura Ryder & Bekker-Jensen, Simon Holst, 2024, In: Molecular Cell. 84, 1, p. 142-155 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome

    Rozario, P., Pinilla, M., Gorse, L., Vind, Anna Constance, Robinson, K. S., Toh, G. A., Firdaus, M. J., Martínez Hernández, José Francisco, Kerk, S. K., Lin, Z., Chambers, J. C., Bekker-Jensen, Simon Holst, Meunier, E. & Zhong, F., 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 2, 12 p., e2309579121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2023
  6. Published

    Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence

    López, A. R., Jørgensen, M. H., Havelund, J. F., Arendrup, Frederic Schrøder, Kolapalli, S. P., Nielsen, T. M., Pais, E., Beese, C. J., Abdul-Al, A., Vind, Anna Constance, Bartek, J., Bekker-Jensen, Simon Holst, Montes, M., Galanos, P., Faergeman, N., Happonen, L. & Frankel, Lisa, 2023, In: Cell Reports. 42, 11, 24 p., 113381.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Computational and Functional Analysis of Structural Features in the ZAKα Kinase

    Johansen, Valdemar Brimnes Ingemann, Snieckute, Goda, Vind, Anna Constance, Blasius, Melanie & Bekker-Jensen, Simon Holst, 2023, In: Cells. 12, 6, 969.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Myofibrillar myopathy hallmarks associated with ZAK deficiency

    Stonadge, A., Genzor Garbayo, Aitana Victoria, Russell, A., Hamed, M. F., Romero, N., Evans, G., Pownall, B., Bekker-Jensen, Simon Holst & Blanco, G., 2023, In: Human Molecular Genetics. 32, 17, p. 2751-2770 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Nitric oxide-induced ribosome collision activates ribosomal surveillance mechanisms

    Jordan, Laura Ryder, Arendrup, Frederic Schrøder, Martínez, J. F., Snieckute, Goda, Pecorari, C., Shah, Riyaz, Lund, Anders H., Blasius, Melanie & Bekker-Jensen, Simon Holst, 2023, In: Cell Death & Disease. 14, 7, 10 p., 467.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    PRMT5-mediated regulatory arginine methylation of RIPK3

    Chauhan, C., Martinez Del Val, Ana, Niedenthal, R., Olsen, Jesper Velgaard, Kotlyarov, A., Bekker-Jensen, Simon Holst, Gaestel, M. & Menon, M. B., 2023, In: Cell Death Discovery. 9, 9 p., 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

    Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Rational Design of Covalent Kinase Inhibitors by an Integrated Computational Workflow (Kin-Cov)

    Zhou, Y., Yu, H., Vind, Anna Constance, Kong, L., Liu, Y., Song, X., Tu, Z., Yun, C., Smaill, J. B., Zhang, Q. W., Ding, K., Bekker-Jensen, Simon Holst & Lu, X., 2023, In: Journal of Medicinal Chemistry. 66, 11, p. 7405–7420

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 14470936