Nicole Schmitt

Nicole Schmitt

Professor MSO


  1. 2000
  2. Published

    A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly.

    Schmitt, Nicole, Schwarz, M., Peretz, A., Abitbol, I., Attali, B. & Pongs, O., 2000, In: EMBO Journal. 19, 3, p. 332-40 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2003
  4. Published

    KCNQ1 channels sense small changes in cell volume.

    Grunnet, Morten, Jespersen, Thomas, MacAulay, Nanna, Jørgensen, N. K., Schmitt, Nicole, Pongs, O., Olesen, Søren-Peter & Klærke, Dan Arne, 2003, In: Journal of Physiology. 549, Pt 2, p. 419-27 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. 2005
  6. Published

    Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome.

    Grunnet, Morten, Behr, E. R., Callø, Kirstine, Hofman-Bang, J., Till, J., Christiansen, M., McKenna, W. J., Olesen, Søren-Peter & Schmitt, Nicole, 2005, In: Heart Rhythm. 2, 11, p. 1238-49 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Local anesthetic interaction with human ether-a-go-go-related gene (HERG) channels: role of aromatic amino acids Y652 and F656.

    Siebrands, C. C., Schmitt, Nicole & Friederich, P., 2005, In: Anesthesiology. 103, 1, p. 102-12 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. 2006
  9. Published

    Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations.

    Shamgar, L., Ma, L., Schmitt, Nicole, Haitin, Y., Peretz, A., Wiener, R., Hirsch, J., Pongs, O. & Attali, B., 2006, In: Circulation Research. 98, 8, p. 1055-63 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Long QT 1 mutation KCNQ1A344V increases local anesthetic sensitivity of the slowly activating delayed rectifier potassium current.

    Siebrands, C. C., Binder, S., Eckhoff, U., Schmitt, Nicole & Friederich, P., 2006, In: Anesthesiology. 105, 3, p. 511-20 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.

    Bentzen, Bo Hjorth, Schmitt, Nicole, Callø, Kirstine, Dalby Brown, W., Grunnet, Morten & Olesen, Søren-Peter, 2006, In: Neuropharmacology. 51, 6, p. 1068-77 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. 2007
  13. Published

    Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

    Callø, Kirstine, Ravn, L. S., Schmitt, Nicole, Sui, J. L., Duno, M., Haunso, S., Grunnet, Morten, Svendsen, J. H. & Olesen, Søren-Peter, 2007, In: Biochemical and Biophysical Research Communications. 364, 4, p. 889-95 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes.

    Callø, Kirstine, Nielsen, Morten Schak, Grunnet, Morten, Schmitt, Nicole & Jorgensen, N. K., 2007, In: BBA General Subjects. 1773, 6, p. 764-73 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval.

    Lundby, Alicia, Ravn, L. S., Svendsen, Jesper Hastrup, Olesen, Søren-Peter & Schmitt, Nicole, 2007, In: Heart Rhythm. 4, 12, p. 1532-41 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Modulation of ERG channels by XE991.

    Elmedyb, P., Callø, Kirstine, Schmitt, Nicole, Hansen, R. S., Grunnet, Morten & Olesen, Søren-Peter, 2007, In: Basic & Clinical Pharmacology & Toxicology. 100, 5, p. 316-22 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Mutations in the Kv1.5 channel gene KCNA5 in cardiac arrest patients.

    Nielsen, N. H., Winkel, B. G., Kanters, Jørgen K., Schmitt, Nicole, Hofman-Bang, J., Jensen, H. S., Bentzen, Bo Hjorth, Sigurd, B., Larsen, Lars Allan, Andersen, P. S., Kjeldsen, K., Grunnet, Morten, Christiansen, M., Olesen, Søren-Peter & Haunsø, Stig, 2007, In: Biochemical and Biophysical Research Communications. 354, 3, p. 776-82 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.

    Rasmussen, Hanne Borger, Frøkjær-Jensen, Christian, Jensen, C. S., Jensen, H. S., Jørgensen, N. K., Misonou, H., Trimmer, J. S., Olesen, Søren-Peter & Schmitt, Nicole, 2007, In: Journal of Cell Science. 120, Pt 6, p. 953-63 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    The novel C-terminal KCNQ1 mutation M520R alters protein trafficking.

    Schmitt, Nicole, Callø, Kirstine, Nielsen, N. H., Buschmann, M., Speckmann, E., Schulze-Bahr, E. & Schwarz, M., 2007, In: Biochemical and Biophysical Research Communications. 358, 1, p. 304-10 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. 2008
  21. Published

    KCNE3 mutation V17M identified in a patient with lone atrial fibrillation.

    Lundby, Alicia, Ravn, L. S., Svendsen, J. H., Hauns, S., Olesen, Søren-Peter & Schmitt, Nicole, 2008, In: Cellular Physiology and Biochemistry. 21, 1-3, p. 47-54 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. 2009
  23. Published

    Functional properties of human neuronal Kv11 channels

    Einarsen, K., Callø, Kirstine, Grunnet, Morten, Olesen, Søren-Peter & Schmitt, Nicole, 2009, In: Pflügers Archiv: European Journal of Physiology. 458, 4, p. 689-700 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Phosphorylation of connexin43 on serine 306 regulates electrical coupling

    Procida, Kristina, Jørgensen, L., Schmitt, Nicole, Delmar, M., Taffet, S. M., von Holstein-Rathlou, Niels-Henrik, Nielsen, Morten Schak & Braunstein, T. H., 2009, In: Heart Rhythm. 6, 11, p. 1632-8 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    The acrylamide (S)-2 as a positive and negative modulator of Kv7 channels expressed in Xenopus laevis oocytes

    Blom, S. M., Schmitt, Nicole & Jensen, H. S., 2009, In: PLoS ONE. 4, 12, p. e8251

    Research output: Contribution to journalJournal articlepeer-review

  26. 2010
  27. Published

    Structural basis for KV7.1/KCNEx interactions in the IKs channel complex

    Lundby, Alicia, Tseng, G. & Schmitt, Nicole, 2010, In: Heart Rhythm. 7, 5, p. 708-713

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Differential effects of ICA-27243 on cloned K(V)7 channels

    Blom, S. M., Schmitt, Nicole & Jensen, H. S., Jan 2010, In: Pharmacology. 86, 3, p. 174-81 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2

    Lundby, Alicia, Jespersen, T., Schmitt, Nicole, Grunnet, M., Olesen, S., Cordeiro, J. M. & Calloe, K., Aug 2010, In: British Journal of Pharmacology. 160, 8, p. 2028-44 17 p.

    Research output: Contribution to journalJournal article

  30. Published

    Overlapping LQT1 and LQT2 phenotype in a patient with long QT syndrome associated with loss-of-function variations in KCNQ1 and KCNH2

    Cordeiro, J. M., Perez, G. J., Schmitt, Nicole, Pfeiffer, R., Nesterenko, V. V., Burashnikov, E., Veltmann, C., Borggrefe, M., Wolpert, C., Schimpf, R. & Antzelevitch, C., Dec 2010, In: Canadian Journal of Physiology and Pharmacology. 88, 12, p. 1181-90 10 p.

    Research output: Contribution to journalJournal article

  31. 2011
  32. Published

    Cellular mechanisms for presynaptic inhibition of sensory afferents.

    Perrier, Jean-Francois Marie, delgado-lezama, R., Christensen, R. K., Lind, B., Schmitt, Nicole, Loeza-Alcocer, E., petersen, A., Lauritzen, Martin & russo, R., 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  33. Published

    Letter by Olesen et al regarding article, "MOG1: a new susceptibility gene for Brugada syndrome"

    Olesen, M. S., Holst, A. G. & Schmitt, Nicole, 2011, In: Circulation: Cardiovascular Genetics. 4, 5

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A

    Calloe, K., Schmitt, Nicole, Grubb, Søren, Pfeiffer, R., David, J., Kanter, R., Cordeiro, J. M., Antzelevitch, C. & Callø, Kirstine, 2011, In: Canadian Journal of Physiology and Pharmacology. 89, 10, p. 723-36 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

    Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias

    Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23

    Research output: Contribution to journalJournal articlepeer-review

  37. 2012
  38. Published

    Cellular mechanisms for presynaptic inhibition of sensory afferents

    Christensen, R. K., Delgado-Lezama, R., russo, R., lind, B., Schmitt, Nicole, LOEZA-ALCOCER, M., Lauritzen, Martin & Perrier, Jean-Francois Marie, 2012. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  39. Published

    High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

    Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation

    Olesen, M. S., Bentzen, Bo Hjorth, Nielsen, J. B., Steffensen, Annette Buur, David, J., Jabbari, J., Jensen, H., Haunsø, Stig, Svendsen, Jesper Hastrup & Schmitt, Nicole, 2012, In: B M C Medical Genetics. 13, p. 24

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation

    Christophersen, I. E., Olesen, M. S., Liang, B., Andersen, M. N., Larsen, A. P., Nielsen, J. B., Haunsø, Stig, Olesen, Søren-Peter, Tveit, A., Svendsen, Jesper Hastrup & Schmitt, Nicole, 21 Dec 2012, In: European Heart Journal.

    Research output: Contribution to journalJournal articlepeer-review

  42. 2013
  43. Published

    A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation

    Olesen, Morten Steen Salling, Refsgaard, L., Holst, A. G., Larsen, A. P., Grubb, Søren, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Schmitt, Nicole & Callø, Kirstine, 2013, In: Cardiovascular Research. 98, 3, p. 488-495 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Characterization and mechanisms of action of novel NaV1.5 channel mutations associated with Brugada syndrome

    Callø, Kirstine, Refaat, M. M., Grubb, Søren, Wojciak, J., Campagna, J., Thomsen, N. M., Nussbaum, R. L., Scheinman, M. M. & Schmitt, Nicole, 2013, In: Circulation. Arrhythmia and Electrophysiology (Online). 6, 1, p. 177-184 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Dysfunction of the heteromeric KV7.3/KV7.5 potassium channel is associated with autism spectrum disorders

    Nielsen, M. G., Rasmussen, Hanne Borger, Callø, Kirstine, F. Sequeira, A., Baretto, M., Oliveira, G., Almeida, J., B. Lauritsen, M., Ullmann, R., Boonen, S. E., Brøndum-Nielsen, K., M. Kalscheuer, V., Tümer, Asuman Zeynep, M. Vicente, A., Schmitt, Nicole & Tommerup, Niels, 2013, In: Frontiers in Genetics. 4, 54, p. 1-13 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Gliadin Fragments and a Specific Gliadin 33-mer Peptide Close KATP Channels and Induce Insulin Secretion in INS-1E Cells and Rat Islets of Langerhans

    Dall, M., Callø, Kirstine, Haupt-Jorgensen, M., Larsen, J., Schmitt, Nicole, Josefsen, K. & Buschard, K., 2013, In: PLOS ONE. 8, 6, p. 1-10 10 p., e66474.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Trafficking of the IKs -Complex in MDCK Cells: Site of Subunit Assembly and Determinants of Polarized Localization

    David, J., Andersen, M. N., Olesen, Søren-Peter, Rasmussen, Hanne Borger & Schmitt, Nicole, Apr 2013, In: Traffic. 14, 4, p. 399-411 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

    Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    A Common Structural Component for β-Subunit Mediated Modulation of Slow Inactivation in Different KV Channels

    Strutz-Seebohm, N., Henrion, U., Schmitt, Nicole, Schulze-Bahr, E. & Seebohm, G., 26 Jun 2013, In: Cellular Physiology and Biochemistry. 31, 6, p. 968-980 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia

    Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Genetic Modifier of the QTc Interval Associated With Early-Onset Atrial Fibrillation

    Andreasen, Laura Korsholm, Nielsen, J. B., Christophersen, I. E., Holst, A. G., Sajadieh, Ahmad, Tveit, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Schmitt, Nicole & Olesen, Morten Steen Salling, Oct 2013, In: Canadian Journal of Cardiology. 29, 10, p. 1234-40 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

    Liang, B., Soka, M., Christensen, Alex Hørby, Olesen, Morten Steen Salling, Larsen, A. P., Knop, Filip Krag, Wang, F., Nielsen, J. B., Andersen, M. N., Humphreys, D., Mann, S. A., Huttner, I. G., Vandenberg, J. I., Svendsen, Jesper Hastrup, Haunsø, Stig, Preiss, T., Seebohm, G., Olesen, Søren-Peter, Schmitt, Nicole & Fatkin, D., 27 Dec 2013, In: Journal of Molecular and Cellular Cardiology. 67, p. 69-76 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. 2014
  54. Published

    Fast detection of extrasynaptic GABA with a whole-cell sniffer

    Christensen, R. K., Petersen, A. V., Schmitt, Nicole & Perrier, Jean-Francois Marie, 2014, In: Frontiers in Cellular Neuroscience. 8, p. 1-9 9 p., 00133.

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

    Yuan, L., Koivumäki, J., Liang, B., Lorentzen, Lasse Gøbel, Tang, C., Andersen, M., Svendsen, J., Tfelt-Hansen, Jacob, Maleckar, M., Schmitt, Nicole, Olesen, M. & Jespersen, Thomas, Feb 2014, In: American journal of physiology. Heart and circulatory physiology.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation

    Olesen, Morten Steen Salling, Andreasen, Laura Korsholm, Jabbari, J., Refsgaard, L., Haunsø, Stig, Olesen, Søren-Peter, Nielsen, J. B., Schmitt, Nicole & Svendsen, Jesper Hastrup, Feb 2014, In: Heart Rhythm. 11, 2, p. 246-251 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

    Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

    Research output: Contribution to journalJournal articlepeer-review

  58. Published

    Specific Sorting and Post-Golgi trafficking of Dendritic Potassium Channels in Living Neurons

    Jensen, C. S., Watanabe, S., Rasmussen, Hanne Borger, Schmitt, Nicole, Olesen, Søren-Peter, Frost, N. A., Blanpied, T. A. & Misonou, H., 25 Feb 2014, In: The Journal of Biological Chemistry. 289, p. 10566-10581 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    Brugada syndrome risk loci seem protective against atrial fibrillation

    Andreasen, Laura Korsholm, Nielsen, J. B., Darkner, S., Christophersen, I. E., Jabbari, J., Refsgaard, L., Thiis, J. J., Sajadieh, Ahmad, Tveit, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Schmitt, Nicole & Olesen, Morten Steen Salling, 26 Mar 2014, In: European Journal of Human Genetics. 22, p. 1357-1361 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia

    Schmitt, Nicole, Grunnet, Morten & Olesen, Søren-Peter, Apr 2014, In: Physiological Reviews. 94, 2, p. 609-53 45 p.

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation

    Nielsen, J. B., Bentzen, Bo Hjorth, Olesen, Morten Steen Salling, David, J., Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup & Schmitt, Nicole, Apr 2014, In: Biomarkers in Medicine. 8, 4, p. 557-570 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  62. Published

    From pan-reactive KV7 channel opener to subtype selective opener/inhibitor by addition of a methyl group

    Blom, S. M., Rottländer, M., Kehler, J., Bundgaard, C., Schmitt, Nicole & Jensen, H. S., Jun 2014, In: PloS one. 9, 6, 9 p., e100209.

    Research output: Contribution to journalJournal articlepeer-review

Previous 1 2 Next

ID: 5624