Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2011
  2. Myeloperoxidase-derived oxidation : mechanisms of biological damage and its prevention. / Davies, Michael Jonathan.

    In: Journal of Clinical Biochemistry and Nutrition, Vol. 48, No. 1, 01.2011, p. 8-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins. / Moheimani, Fatemeh; Tan, Joanne T M; Brown, Bronwyn E; Heather, Alison K; van Reyk, David M; Davies, Michael Jonathan.

    In: Journal of Diabetes Research, Vol. 2011, 2011, p. 851280.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2010
  5. Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3. / Peskin, Alexander V; Cox, Andrew G; Nagy, Péter; Morgan, Philip E; Hampton, Mark B; Davies, Michael Jonathan; Winterbourn, Christine C.

    In: Biochemical Journal, Vol. 432, No. 2, 01.12.2010, p. 313-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk : A cross-sectional study. / Gray, Laura J.; Tringham, Jennifer R.; Davies, Melanie J.; Webb, David R.; Jarvis, Janet; Skinner, Timothy C.; Farooqi, Azhar M.; Khunti, Kamlesh.

    In: Vascular Health and Risk Management, Vol. 6, No. 1, 01.12.2010, p. 837-842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts. / Rahmanto, Aldwin Suryo; Morgan, Philip E; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 49, No. 10, 30.11.2010, p. 1505-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes : Cost effectiveness analysis. / Gillett, M.; Dallosso, H. M.; Dixon, S.; Brennan, A.; Carey, M. E.; Campbell, M. J.; Heller, S.; Khunti, K.; Skinner, T. C.; Davies, M. J.

    In: BMJ (Online), Vol. 341, No. 7770, c4093, 26.08.2010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages. / Lane, Amanda E; Tan, Joanne T M; Hawkins, Clare Louise; Heather, Alison K; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 430, No. 1, 15.08.2010, p. 161-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Depressive symptoms in the first year from diagnosis of Type 2 diabetes : Results from the DESMOND trial. / Skinner, T. C.; Carey, M. E.; Cradock, S.; Dallosso, H. M.; Daly, H.; Davies, M. J.; Doherty, Y.; Heller, S.; Khunti, K.; Oliver, L.

    In: Diabetic Medicine, Vol. 27, No. 8, 01.08.2010, p. 965-967.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus : A comparison of two screening tools. / Aujla, N.; Skinner, T. C.; Khunti, K.; Davies, M. J.

    In: Diabetic Medicine, Vol. 27, No. 8, 01.08.2010, p. 896-905.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains. / Kennett, Eleanor C; Rees, Martin D; Malle, Ernst; Hammer, Astrid; Whitelock, John M; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 49, No. 2, 15.07.2010, p. 282-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function : possible links between diabetes and atherosclerosis. / Moheimani, Fatemeh; Morgan, Philip E; van Reyk, David M; Davies, Michael Jonathan.

    In: B B A - Reviews on Cancer, Vol. 1802, No. 6, 06.2010, p. 561-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations. / Koelsch, Maud; Mallak, Roger; Graham, Garry G; Kajer, Tracey; Milligan, Marian K; Nguyen, Ly Q; Newsham, Dawn W; Keh, Jeremy S; Kettle, Anthony J; Scott, Kieran F; Ziegler, John B; Pattison, David I; Fu, Shanlin; Hawkins, Clare Louise; Rees, Martin D; Davies, Michael Jonathan.

    In: Biochemical Pharmacology, Vol. 79, No. 8, 15.04.2010, p. 1156-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Cellular effects of peptide and protein hydroperoxides. / Rahmanto, Aldwin Suryo; Morgan, Philip E; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 48, No. 8, 15.04.2010, p. 1071-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans : A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study. / Khunti, Kamlesh; Taub, Nick; Tringham, Jennifer; Jarvis, Janet; Farooqi, Azhar; Skinner, T. Chas; Davies, Melanie J.

    In: Primary Care Diabetes, Vol. 4, No. 1, 01.04.2010, p. 25-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I. / Nobécourt, Estelle; Tabet, Fatiha; Lambert, Gilles; Puranik, Rajesh; Bao, Shisan; Yan, Ling; Davies, Michael Jonathan; Brown, Bronwyn E; Jenkins, Alicia J; Dusting, Gregory J; Bonnet, David J; Curtiss, Linda K; Barter, Philip J; Rye, Kerry-Anne.

    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 30, No. 4, 04.2010, p. 766-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The association between depression and health-related quality of life in people with type 2 diabetes : A systematic literature review. / Ali, Saima; Stone, Margaret; Skinner, Timothy Chas; Robertson, Noelle; Davies, Melanie; Khunti, Kamlesh.

    In: Diabetes/Metabolism Research and Reviews, Vol. 26, No. 2, 01.02.2010, p. 75-89.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction. / Szuchman-Sapir, Andrea J; Pattison, David I; Davies, Michael Jonathan; Witting, Paul K.

    In: Free Radical Biology & Medicine, Vol. 48, No. 1, 01.01.2010, p. 35-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan. / Rees, Martin D; Whitelock, John M; Malle, Ernst; Chuang, Christine Y; Iozzo, Renato V; Nilasaroya, Anastasia; Davies, Michael Jonathan.

    In: Matrix Biology, Vol. 29, No. 1, 01.2010, p. 63-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy. / Sourris, Karly C; Harcourt, Brooke E; Penfold, Sally A; Yap, Felicia Y T; Morley, Amy L; Morgan, Philip E; Davies, Michael Jonathan; Baker, Scott T; Jerums, George; Forbes, Josephine M.

    In: Journal of Diabetes Research, Vol. 2010, 2010, p. 974681.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2009
  23. Published

    The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus. / Aujla, Navneet; Abrams, Keith R.; Davies, Melanie J.; Taub, Nick; Skinner, Timothy C.; Khunti, Kamlesh.

    In: PLoS ONE, Vol. 4, No. 11, e7755, 09.11.2009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner : implications for peroxynitrite-mediated damage at sites of inflammation. / Kennett, Eleanor C; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 47, No. 4, 15.08.2009, p. 389-400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols : absolute rate constants and assessment of biological relevance. / Skaff, Ojia; Pattison, David I; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 422, No. 1, 15.08.2009, p. 111-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides. / Rees, Martin D; Bottle, Steven E; Fairfull-Smith, Kathryn E; Malle, Ernst; Whitelock, John M; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 421, No. 1, 01.07.2009, p. 79-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Singlet-oxygen-mediated amino acid and protein oxidation : formation of tryptophan peroxides and decomposition products. / Gracanin, Michelle; Hawkins, Clare Louise; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 47, No. 1, 01.07.2009, p. 92-102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach. / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 22, No. 5, 05.2009, p. 807-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Quantification of protein modification by oxidants. / Hawkins, Clare Louise; Morgan, Philip E; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 46, No. 8, 15.04.2009, p. 965-88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Hypobromous acid and bromamine production by neutrophils and modulation by superoxide. / Chapman, Anna L P; Skaff, Ojia; Senthilmohan, Revathy; Kettle, Anthony J; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 417, No. 3, 01.02.2009, p. 773-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients. / Morgan, Philip E; Sturgess, Allan D; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 43, No. 2, 02.2009, p. 117-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2008
  33. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation. / Hawkins, Clare Louise; Pattison, David I; Stanley, Naomi R; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 416, No. 3, 15.12.2008, p. 441-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes : Baseline data from the DESMOND randomized controlled trial. / Khunti, K.; Skinner, T. C.; Heller, S.; Carey, M. E.; Dallosso, H. M.; Davies, M. J.

    In: Diabetic Medicine, Vol. 25, No. 12, 01.12.2008, p. 1454-1461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins. / Morgan, Philip E; Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 45, No. 9, 01.11.2008, p. 1279-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals. / Lam, Magdalena A; Pattison, David I; Bottle, Steven E; Keddie, Daniel J; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 21, No. 11, 11.2008, p. 2111-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin. / Szuchman-Sapir, Andrea J; Pattison, David I; Ellis, Natasha A; Hawkins, Clare Louise; Davies, Michael Jonathan; Witting, Paul K.

    In: Free Radical Biology & Medicine, Vol. 45, No. 6, 15.09.2008, p. 789-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    'Educator talk' and patient change : Some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial. / Skinner, T. C.; Carey, M. E.; Cradock, S.; Dallosso, H. M.; Daly, H.; Davies, M. J.; Doherty, Y.; Heller, S.; Khunti, K.; Oliver, L.

    In: Diabetic Medicine, Vol. 25, No. 9, 01.09.2008, p. 1117-1120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid. / Kennett, Eleanor C; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 45, No. 5, 01.09.2008, p. 716-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid. / Lloyd, Mitchell M; van Reyk, David M; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Biochemical Journal, Vol. 414, No. 2, 01.09.2008, p. 271-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines. / Summers, Fiona A; Morgan, Philip E; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Chemical Research in Toxicology, Vol. 21, No. 9, 09.2008, p. 1832-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants : a kinetic study. / Skaff, Ojia; Pattison, David I; Davies, Michael Jonathan.

    In: Biochemistry, Vol. 47, No. 31, 05.08.2008, p. 8237-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Waiting for diabetes : Perceptions of people with pre-diabetes: A qualitative study. / Troughton, Jacqui; Jarvis, Janet; Skinner, Chas; Robertson, Noelle; Khunti, Kamlesh; Davies, Melanie.

    In: Patient Education and Counseling, Vol. 72, No. 1, 01.07.2008, p. 88-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Mammalian heme peroxidases : from molecular mechanisms to health implications. / Davies, Michael Jonathan; Hawkins, Clare Louise; Pattison, David I; Rees, Martin D.

    In: Antioxidants & Redox Signaling, Vol. 10, No. 7, 07.2008, p. 1199-234.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Oxidative damage to extracellular matrix and its role in human pathologies. / Rees, Martin D; Kennett, Eleanor C; Whitelock, John M; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 44, No. 12, 15.06.2008, p. 1973-2001.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation. / Stadler, Nadina; Stanley, Naomi; Heeneman, Sylvia; Vacata, Vladimir; Daemen, Mat J A P; Bannon, Paul G; Waltenberger, Johannes; Davies, Michael Jonathan.

    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 28, No. 5, 05.2008, p. 1024-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage. / Mizdrak, Jasminka; Hains, Peter G; Truscott, Roger J W; Jamie, Joanne F; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 44, No. 6, 15.03.2008, p. 1108-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes : Cluster randomised controlled trial. / Davies, M. J.; Heller, S.; Skinner, T. C.; Campbell, M. J.; Carey, M. E.; Cradock, S.; Dallosso, H. M.; Daly, H.; Doherty, Y.; Eaton, S.; Fox, C.; Oliver, L.; Rantell, K.; Rayman, G.; Khunti, K.

    In: BMJ, Vol. 336, No. 7642, 01.03.2008, p. 491-495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The DESMOND educational intervention. / Davies, M. J.; Heller, S.; Khunti, K.; Skinner, T. C.

    In: Chronic Illness, Vol. 4, No. 1, 01.03.2008, p. 38-40.

    Research output: Contribution to journalComment/debateResearchpeer-review

  50. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links. / Lametsch, Marianne Lund; Luxford, Catherine; Skibsted, Leif Horsfelt; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 410, No. 3, 2008, p. 565-574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2007
  52. Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants. / Skaff, Ojia; Pattison, David I; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 20, No. 12, 12.2007, p. 1980-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis. / Morgan, Philip E; Sturgess, Allan D; Hennessy, Annemarie; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 41, No. 12, 12.2007, p. 1301-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides. / Dremina, Elena S; Sharov, Victor S; Davies, Michael Jonathan; Schöneich, Christian.

    In: Chemical Research in Toxicology, Vol. 20, No. 10, 10.2007, p. 1462-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Hypochlorous acid-mediated protein oxidation : how important are chloramine transfer reactions and protein tertiary structure? / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Biochemistry, Vol. 46, No. 34, 28.08.2007, p. 9853-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205