Michael Jonathan Davies

Michael Jonathan Davies

Professor

  • Inflammation, Metabolism and Oxidation

    Blegdamsvej 3, 2200 København N, 12.6, Building: 30

    Phone: +45 35 33 69 77Mobile: +45 23 64 94 45

  1. 2006
  2. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols. / Zeng, Jingmin; Dunlop, Rachael A; Rodgers, Kenneth J; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 398, No. 2, 01.09.2006, p. 197-206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Protein and low molecular mass thiols as targets and inhibitors of glycation reactions. / Zeng, Jingmin; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 19, No. 12, 12.2006, p. 1668-76.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Diabetes education and self-management for ongoing and newly diagnosed (DESMOND) : Process modelling of pilot study. / Skinner, T. Chas; Carey, Marian E.; Cradock, Sue; Daly, Heather; Davies, Melanie J.; Doherty, Yvonne; Heller, Simon; Khunti, Kamlesh; Oliver, Lindsay.

    In: Patient Education and Counseling, Vol. 64, No. 1-3, 01.12.2006, p. 369-377.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2007
  6. Degradation of extracellular matrix and its components by hypobromous acid. / Rees, Martin D; McNiven, Tane N; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 401, No. 2, 15.01.2007, p. 587-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages. / Brown, Bronwyn E; Rashid, Imran; van Reyk, David M; Davies, Michael Jonathan.

    In: F E B S Journal, Vol. 274, No. 6, 03.2007, p. 1530-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro. / Rashid, Imran; van Reyk, David M; Davies, Michael Jonathan.

    In: FEBS letters, Vol. 581, No. 5, 06.03.2007, p. 1067-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid : evidence for a hydroxyl-radical-like mechanism. / Kennett, Eleanor C; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 42, No. 8, 15.04.2007, p. 1278-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides : potential modulation of cell signaling by protein oxidation products. / Gracanin, Michelle; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 42, No. 10, 15.05.2007, p. 1543-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A randomized controlled trial examining combinations of repaglinide, metformin and NPH insulin. / Davies, M. J.; Thaware, P. K.; Tringham, J. R.; Howe, J.; Jarvis, J.; Johnston, V.; Kitchener, D. L.; Skinner, T. C.; McNally, P. G.; Lawrence, I. G.

    In: Diabetic Medicine, Vol. 24, No. 7, 01.07.2007, p. 714-719.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Reversible binding of kynurenine to lens proteins : potential protection by glutathione in young lenses. / Parker, Nicole R; Korlimbinis, Anastasia; Jamie, Joanne F; Davies, Michael Jonathan; Truscott, Roger J W.

    In: Investigative Ophthalmology & Visual Science, Vol. 48, No. 8, 08.2007, p. 3705-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Hypochlorous acid-mediated protein oxidation : how important are chloramine transfer reactions and protein tertiary structure? / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Biochemistry, Vol. 46, No. 34, 28.08.2007, p. 9853-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides. / Dremina, Elena S; Sharov, Victor S; Davies, Michael Jonathan; Schöneich, Christian.

    In: Chemical Research in Toxicology, Vol. 20, No. 10, 10.2007, p. 1462-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants. / Skaff, Ojia; Pattison, David I; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 20, No. 12, 12.2007, p. 1980-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis. / Morgan, Philip E; Sturgess, Allan D; Hennessy, Annemarie; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 41, No. 12, 12.2007, p. 1301-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2008
  18. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links. / Lametsch, Marianne Lund; Luxford, Catherine; Skibsted, Leif Horsfelt; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 410, No. 3, 2008, p. 565-574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes : Cluster randomised controlled trial. / Davies, M. J.; Heller, S.; Skinner, T. C.; Campbell, M. J.; Carey, M. E.; Cradock, S.; Dallosso, H. M.; Daly, H.; Doherty, Y.; Eaton, S.; Fox, C.; Oliver, L.; Rantell, K.; Rayman, G.; Khunti, K.

    In: BMJ, Vol. 336, No. 7642, 01.03.2008, p. 491-495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The DESMOND educational intervention. / Davies, M. J.; Heller, S.; Khunti, K.; Skinner, T. C.

    In: Chronic Illness, Vol. 4, No. 1, 01.03.2008, p. 38-40.

    Research output: Contribution to journalComment/debateResearchpeer-review

  21. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage. / Mizdrak, Jasminka; Hains, Peter G; Truscott, Roger J W; Jamie, Joanne F; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 44, No. 6, 15.03.2008, p. 1108-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation. / Stadler, Nadina; Stanley, Naomi; Heeneman, Sylvia; Vacata, Vladimir; Daemen, Mat J A P; Bannon, Paul G; Waltenberger, Johannes; Davies, Michael Jonathan.

    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 28, No. 5, 05.2008, p. 1024-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Oxidative damage to extracellular matrix and its role in human pathologies. / Rees, Martin D; Kennett, Eleanor C; Whitelock, John M; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 44, No. 12, 15.06.2008, p. 1973-2001.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Mammalian heme peroxidases : from molecular mechanisms to health implications. / Davies, Michael Jonathan; Hawkins, Clare Louise; Pattison, David I; Rees, Martin D.

    In: Antioxidants & Redox Signaling, Vol. 10, No. 7, 07.2008, p. 1199-234.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Waiting for diabetes : Perceptions of people with pre-diabetes: A qualitative study. / Troughton, Jacqui; Jarvis, Janet; Skinner, Chas; Robertson, Noelle; Khunti, Kamlesh; Davies, Melanie.

    In: Patient Education and Counseling, Vol. 72, No. 1, 01.07.2008, p. 88-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants : a kinetic study. / Skaff, Ojia; Pattison, David I; Davies, Michael Jonathan.

    In: Biochemistry, Vol. 47, No. 31, 05.08.2008, p. 8237-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines. / Summers, Fiona A; Morgan, Philip E; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Chemical Research in Toxicology, Vol. 21, No. 9, 09.2008, p. 1832-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    'Educator talk' and patient change : Some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial. / Skinner, T. C.; Carey, M. E.; Cradock, S.; Dallosso, H. M.; Daly, H.; Davies, M. J.; Doherty, Y.; Heller, S.; Khunti, K.; Oliver, L.

    In: Diabetic Medicine, Vol. 25, No. 9, 01.09.2008, p. 1117-1120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid. / Kennett, Eleanor C; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 45, No. 5, 01.09.2008, p. 716-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid. / Lloyd, Mitchell M; van Reyk, David M; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Biochemical Journal, Vol. 414, No. 2, 01.09.2008, p. 271-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin. / Szuchman-Sapir, Andrea J; Pattison, David I; Ellis, Natasha A; Hawkins, Clare Louise; Davies, Michael Jonathan; Witting, Paul K.

    In: Free Radical Biology & Medicine, Vol. 45, No. 6, 15.09.2008, p. 789-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals. / Lam, Magdalena A; Pattison, David I; Bottle, Steven E; Keddie, Daniel J; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 21, No. 11, 11.2008, p. 2111-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins. / Morgan, Philip E; Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 45, No. 9, 01.11.2008, p. 1279-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes : Baseline data from the DESMOND randomized controlled trial. / Khunti, K.; Skinner, T. C.; Heller, S.; Carey, M. E.; Dallosso, H. M.; Davies, M. J.

    In: Diabetic Medicine, Vol. 25, No. 12, 01.12.2008, p. 1454-1461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation. / Hawkins, Clare Louise; Pattison, David I; Stanley, Naomi R; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 416, No. 3, 15.12.2008, p. 441-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2009
  37. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients. / Morgan, Philip E; Sturgess, Allan D; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 43, No. 2, 02.2009, p. 117-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Hypobromous acid and bromamine production by neutrophils and modulation by superoxide. / Chapman, Anna L P; Skaff, Ojia; Senthilmohan, Revathy; Kettle, Anthony J; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 417, No. 3, 01.02.2009, p. 773-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Quantification of protein modification by oxidants. / Hawkins, Clare Louise; Morgan, Philip E; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 46, No. 8, 15.04.2009, p. 965-88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach. / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 22, No. 5, 05.2009, p. 807-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides. / Rees, Martin D; Bottle, Steven E; Fairfull-Smith, Kathryn E; Malle, Ernst; Whitelock, John M; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 421, No. 1, 01.07.2009, p. 79-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Singlet-oxygen-mediated amino acid and protein oxidation : formation of tryptophan peroxides and decomposition products. / Gracanin, Michelle; Hawkins, Clare Louise; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 47, No. 1, 01.07.2009, p. 92-102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner : implications for peroxynitrite-mediated damage at sites of inflammation. / Kennett, Eleanor C; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 47, No. 4, 15.08.2009, p. 389-400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols : absolute rate constants and assessment of biological relevance. / Skaff, Ojia; Pattison, David I; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 422, No. 1, 15.08.2009, p. 111-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus. / Aujla, Navneet; Abrams, Keith R.; Davies, Melanie J.; Taub, Nick; Skinner, Timothy C.; Khunti, Kamlesh.

    In: PLoS ONE, Vol. 4, No. 11, e7755, 09.11.2009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2010
  47. Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy. / Sourris, Karly C; Harcourt, Brooke E; Penfold, Sally A; Yap, Felicia Y T; Morley, Amy L; Morgan, Philip E; Davies, Michael Jonathan; Baker, Scott T; Jerums, George; Forbes, Josephine M.

    In: Journal of Diabetes Research, Vol. 2010, 2010, p. 974681.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan. / Rees, Martin D; Whitelock, John M; Malle, Ernst; Chuang, Christine Y; Iozzo, Renato V; Nilasaroya, Anastasia; Davies, Michael Jonathan.

    In: Matrix Biology, Vol. 29, No. 1, 01.2010, p. 63-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction. / Szuchman-Sapir, Andrea J; Pattison, David I; Davies, Michael Jonathan; Witting, Paul K.

    In: Free Radical Biology & Medicine, Vol. 48, No. 1, 01.01.2010, p. 35-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The association between depression and health-related quality of life in people with type 2 diabetes : A systematic literature review. / Ali, Saima; Stone, Margaret; Skinner, Timothy Chas; Robertson, Noelle; Davies, Melanie; Khunti, Kamlesh.

    In: Diabetes/Metabolism Research and Reviews, Vol. 26, No. 2, 01.02.2010, p. 75-89.

    Research output: Contribution to journalReviewResearchpeer-review

  51. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I. / Nobécourt, Estelle; Tabet, Fatiha; Lambert, Gilles; Puranik, Rajesh; Bao, Shisan; Yan, Ling; Davies, Michael Jonathan; Brown, Bronwyn E; Jenkins, Alicia J; Dusting, Gregory J; Bonnet, David J; Curtiss, Linda K; Barter, Philip J; Rye, Kerry-Anne.

    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 30, No. 4, 04.2010, p. 766-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans : A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study. / Khunti, Kamlesh; Taub, Nick; Tringham, Jennifer; Jarvis, Janet; Farooqi, Azhar; Skinner, T. Chas; Davies, Melanie J.

    In: Primary Care Diabetes, Vol. 4, No. 1, 01.04.2010, p. 25-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations. / Koelsch, Maud; Mallak, Roger; Graham, Garry G; Kajer, Tracey; Milligan, Marian K; Nguyen, Ly Q; Newsham, Dawn W; Keh, Jeremy S; Kettle, Anthony J; Scott, Kieran F; Ziegler, John B; Pattison, David I; Fu, Shanlin; Hawkins, Clare Louise; Rees, Martin D; Davies, Michael Jonathan.

    In: Biochemical Pharmacology, Vol. 79, No. 8, 15.04.2010, p. 1156-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Cellular effects of peptide and protein hydroperoxides. / Rahmanto, Aldwin Suryo; Morgan, Philip E; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 48, No. 8, 15.04.2010, p. 1071-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function : possible links between diabetes and atherosclerosis. / Moheimani, Fatemeh; Morgan, Philip E; van Reyk, David M; Davies, Michael Jonathan.

    In: B B A - Reviews on Cancer, Vol. 1802, No. 6, 06.2010, p. 561-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains. / Kennett, Eleanor C; Rees, Martin D; Malle, Ernst; Hammer, Astrid; Whitelock, John M; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 49, No. 2, 15.07.2010, p. 282-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Depressive symptoms in the first year from diagnosis of Type 2 diabetes : Results from the DESMOND trial. / Skinner, T. C.; Carey, M. E.; Cradock, S.; Dallosso, H. M.; Daly, H.; Davies, M. J.; Doherty, Y.; Heller, S.; Khunti, K.; Oliver, L.

    In: Diabetic Medicine, Vol. 27, No. 8, 01.08.2010, p. 965-967.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus : A comparison of two screening tools. / Aujla, N.; Skinner, T. C.; Khunti, K.; Davies, M. J.

    In: Diabetic Medicine, Vol. 27, No. 8, 01.08.2010, p. 896-905.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages. / Lane, Amanda E; Tan, Joanne T M; Hawkins, Clare Louise; Heather, Alison K; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 430, No. 1, 15.08.2010, p. 161-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes : Cost effectiveness analysis. / Gillett, M.; Dallosso, H. M.; Dixon, S.; Brennan, A.; Carey, M. E.; Campbell, M. J.; Heller, S.; Khunti, K.; Skinner, T. C.; Davies, M. J.

    In: BMJ (Online), Vol. 341, No. 7770, c4093, 26.08.2010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts. / Rahmanto, Aldwin Suryo; Morgan, Philip E; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 49, No. 10, 30.11.2010, p. 1505-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3. / Peskin, Alexander V; Cox, Andrew G; Nagy, Péter; Morgan, Philip E; Hampton, Mark B; Davies, Michael Jonathan; Winterbourn, Christine C.

    In: Biochemical Journal, Vol. 432, No. 2, 01.12.2010, p. 313-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk : A cross-sectional study. / Gray, Laura J.; Tringham, Jennifer R.; Davies, Melanie J.; Webb, David R.; Jarvis, Janet; Skinner, Timothy C.; Farooqi, Azhar M.; Khunti, Kamlesh.

    In: Vascular Health and Risk Management, Vol. 6, No. 1, 01.12.2010, p. 837-842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. 2011
  65. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins. / Moheimani, Fatemeh; Tan, Joanne T M; Brown, Bronwyn E; Heather, Alison K; van Reyk, David M; Davies, Michael Jonathan.

    In: Journal of Diabetes Research, Vol. 2011, 2011, p. 851280.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Myeloperoxidase-derived oxidation : mechanisms of biological damage and its prevention. / Davies, Michael Jonathan.

    In: Journal of Clinical Biochemistry and Nutrition, Vol. 48, No. 1, 01.2011, p. 8-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome. / Gracanin, Michelle; Lam, Magdalena A; Morgan, Philip E; Rodgers, Kenneth J; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 50, No. 2, 15.01.2011, p. 389-99.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes : Results from the DESMOND trial. / Skinner, T. C.; Carey, M. E.; Cradock, S.; Dallosso, H. M.; Dalyb, H.; Davies, M. J.; Doherty, Y.; Heller, S.; Khunti, K.; Olivere, L.

    In: Psychology and Health, Vol. 26, No. 3, 01.03.2011, p. 321-335.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. One-electron reduction of N-chlorinated and N-brominated species is a source of radicals and bromine atom formation. / Pattison, David I; O'Reilly, Robert J; Skaff, Ojia; Radom, Leo; Anderson, Robert F; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 24, No. 3, 21.03.2011, p. 371-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    The association between anxiety and measures of glycaemia in a population-based diabetes screening programme. / Aujla, N.; Davies, M. J.; Skinner, T. C.; Gray, L. J.; Webb, D. R.; Srinivasan, B.; Khunti, K.

    In: Diabetic Medicine, Vol. 28, No. 7, 01.07.2011, p. 785-788.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation. / Dalsgaard, Trine K; Nielsen, Jacob H; Brown, Bronwyn E; Stadler, Nadina; Davies, Michael Jonathan.

    In: Journal of Agricultural and Food Chemistry, Vol. 59, No. 14, 27.07.2011, p. 7939-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima. / Mai, Kelly; Smith, Nicholas C; Feng, Zhi-Ping; Katrib, Marilyn; Slapeta, Jan; Slapetova, Iveta; Wallach, Michael G; Luxford, Catherine; Davies, Michael Jonathan; Zhang, Xuecheng; Norton, Raymond S; Belli, Sabina I.

    In: International Journal for Parasitology (Online), Vol. 41, No. 11, 09.2011, p. 1157-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria : The Microalbuminuria Education and Medication Optimisation (MEMO) study. / Crasto, W.; Jarvis, J.; Khunti, K.; Skinner, T. C.; Gray, L. J.; Brela, J.; Troughton, J.; Daly, H.; Lawrence, I. G.; McNally, P. G.; Carey, M. E.; Davies, M. J.

    In: Diabetes Research and Clinical Practice, Vol. 93, No. 3, 01.09.2011, p. 328-336.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Synthesis and antioxidant capacity of 5-selenopyranose derivatives. / Storkey, Corin; Davies, Michael Jonathan; White, Jonathan M; Schiesser, Carl H.

    In: Chemical communications (Cambridge, England), Vol. 47, No. 34, 14.09.2011, p. 9693-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Mechanisms and consequences of oxidative damage to extracellular matrix. / Kennett, Eleanor C; Chuang, Christine Y; Degendorfer, Georg; Whitelock, John M; Davies, Michael Jonathan.

    In: Biochemical Society Transactions, Vol. 39, No. 5, 10.2011, p. 1279-87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase. / Morgan, Philip E; Pattison, David I; Talib, Jihan; Summers, Fiona A; Harmer, Jason A; Celermajer, David S; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 51, No. 9, 01.11.2011, p. 1815-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Catalytic activity of selenomethionine in removing amino acid, peptide, and protein hydroperoxides. / Suryo Rahmanto, Aldwin; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 51, No. 12, 15.12.2011, p. 2288-99.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. 2012
  79. Free Radical Research origins. / Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 46, No. 1, 01.2012, p. 1.

    Research output: Contribution to journalJournal articleResearch

  80. Photo-oxidation of proteins. / Pattison, David I; Rahmanto, Aldwin Suryo; Davies, Michael Jonathan.

    In: Photochemical & Photobiological Sciences, Vol. 11, No. 1, 01.2012, p. 38-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid : determination of absolute rate constants and implications for biological damage. / Skaff, Ojia; Pattison, David I; Morgan, Philip E; Bachana, Rushad; Jain, Vimal K; Priyadarsini, K Indira; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 441, No. 1, 01.01.2012, p. 305-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline. / Morgan, Philip E; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 52, No. 2, 15.01.2012, p. 328-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells. / Cook, Naomi L; Viola, Helena M; Sharov, Victor S; Hool, Livia C; Schöneich, Christian; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 52, No. 5, 01.03.2012, p. 951-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Inactivation of thiol-dependent enzymes by hypothiocyanous acid : role of sulfenyl thiocyanate and sulfenic acid intermediates. / Barrett, Tessa J; Pattison, David I; Leonard, Stephen E; Carroll, Kate S; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Free Radical Biology & Medicine, Vol. 52, No. 6, 15.03.2012, p. 1075-85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine? / Truscott, Roger J W; Mizdrak, Jasminka; Friedrich, Michael G; Hooi, Michelle Y; Lyons, Brian; Jamie, Joanne F; Davies, Michael Jonathan; Wilmarth, Phillip A; David, Larry L.

    In: Experimental Eye Research, Vol. 99, 06.2012, p. 48-54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Reduced metal ion concentrations in atherosclerotic plaques from subjects with type 2 diabetes mellitus. / Stadler, Nadina; Heeneman, Sylvia; Vöö, Stefan; Stanley, Naomi; Giles, Gregory I; Gang, Bevan P; Croft, Kevin D; Mori, Trevor A; Vacata, Vladimir; Daemen, Mat J A P; Waltenberger, Johannes; Davies, Michael Jonathan.

    In: Atherosclerosis, Vol. 222, No. 2, 06.2012, p. 512-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus : Three year follow-up of a cluster randomised controlled trial in primary care. / Khunti, Kamlesh; Gray, Laura J.; Skinner, Timothy; Carey, Marian E.; Realf, Kathryn; Dallosso, Helen; Fisher, Harriet; Campbell, Michael; Heller, Simon; Davies, Melanie J.

    In: BMJ (Online), Vol. 344, No. 7860, e2333, 09.06.2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations : a potential contributory factor in diabetes-associated atherosclerosis. / Moheimani, Fatemeh; Kim, Christine H J; Rahmanto, Aldwin Suryo; van Reyk, David M; Davies, Michael Jonathan.

    In: Atherosclerosis, Vol. 223, No. 1, 07.2012, p. 144-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine. / Talib, Jihan; Pattison, David I; Harmer, Jason A; Celermajer, David S; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 53, No. 1, 01.07.2012, p. 20-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Reactions and reactivity of myeloperoxidase-derived oxidants : differential biological effects of hypochlorous and hypothiocyanous acids. / Pattison, David I; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Free Radical Research, Vol. 46, No. 8, 08.2012, p. 975-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Photo-oxidation-induced inactivation of the selenium-containing protective enzymes thioredoxin reductase and glutathione peroxidase. / Suryo Rahmanto, Aldwin; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 53, No. 6, 15.09.2012, p. 1308-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Selenium-containing amino acids as direct and indirect antioxidants. / Rahmanto, Aldwin Suryo; Davies, Michael Jonathan.

    In: I U B M B Life, Vol. 64, No. 11, 11.2012, p. 863-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. The nitroxide TEMPO is an efficient scavenger of protein radicals : cellular and kinetic studies. / Pattison, David I; Lam, Magdalena; Shinde, Sujata S; Anderson, Robert F; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 53, No. 9, 01.11.2012, p. 1664-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Preventing protein oxidation with sugars : scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives. / Storkey, Corin; Pattison, David I; White, Jonathan M; Schiesser, Carl H; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 25, No. 11, 19.11.2012, p. 2589-99.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Computational design of effective, bioinspired HOCl antioxidants : the role of intramolecular Cl+ and H+ shifts. / Karton, Amir; O'Reilly, Robert J; Pattison, David I; Davies, Michael Jonathan; Radom, Leo.

    In: Journal of the American Chemical Society, Vol. 134, No. 46, 21.11.2012, p. 19240-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins. / Cook, Naomi L; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 53, No. 11, 01.12.2012, p. 2072-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. 2013
  98. Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages. / Brown, Bronwyn E; Nobecourt, Estelle; Zeng, Jingmin; Jenkins, Alicia J; Rye, Kerry-Anne; Davies, Michael Jonathan.

    In: PLOS ONE, Vol. 8, No. 5, 2013, p. e65430.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content. / Thallas-Bonke, Vicki; Coughlan, Melinda T; Tan, Adeline Ly; Harcourt, Brooke E; Morgan, Philip E; Davies, Michael Jonathan; Bach, Leon A; Cooper, Mark E; Forbes, Josephine M.

    In: Nephrology, Vol. 18, No. 1, 01.2013, p. 47-56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins : comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl). / Hadfield, Katrina A; Pattison, David I; Brown, Bronwyn E; Hou, Liming; Rye, Kerry-Anne; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Biochemical Journal, Vol. 449, No. 2, 15.01.2013, p. 531-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals : role of oxidizable amino acid residues. / Arenas, Andrea; López-Alarcón, Camilo; Kogan, Marcelo; Lissi, Eduardo; Davies, Michael Jonathan; Silva, Eduardo.

    In: Chemical Research in Toxicology, Vol. 26, No. 1, 18.01.2013, p. 67-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. The modern pharmacology of paracetamol : therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings. / Graham, Garry G; Davies, Michael Jonathan; Day, Richard O; Mohamudally, Anthoulla; Scott, Kieran F.

    In: Inflammopharmacology, Vol. 21, No. 3, 06.2013, p. 201-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Biomarkers of oxidative stress study V : ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine. / Kadiiska, Maria B; Basu, Samar; Brot, Nathan; Cooper, Christopher; Saari Csallany, A; Davies, Michael Jonathan; George, Magdalene M; Murray, Dennis M; Jackson Roberts, L; Shigenaga, Mark K; Sohal, Rajindar S; Stocker, Roland; Van Thiel, David H; Wiswedel, Ingrid; Hatch, Gary E; Mason, Ronald P.

    In: Free Radical Biology & Medicine, Vol. 61, 08.2013, p. 408-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes. / Morgan, Philip E; Sheahan, Pamela J; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 61, 08.2013, p. 229-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Superoxide radicals have a protective role during H2O2 stress. / Thorpe, Geoffrey W; Reodica, Mayfebelle; Davies, Michael Jonathan; Heeren, Gino; Jarolim, Stefanie; Pillay, Bethany; Breitenbach, Michael; Higgins, Vincent J; Dawes, Ian W.

    In: Molecular Biology of the Cell, Vol. 24, No. 18, 09.2013, p. 2876-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells. / Lloyd, Mitchell M; Grima, Michael A; Rayner, Benjamin S; Hadfield, Katrina A; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Free Radical Biology & Medicine, Vol. 65, 12.2013, p. 1352-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. 2014
  108. Published

    Competitive reduction of perferrylmyoglobin radicals by protein thiols and plant phenols. / Jongberg, Sisse; Lametsch, Marianne Lund; Skibsted, Leif Horsfelt; Davies, Michael Jonathan.

    In: Journal of Agricultural and Food Chemistry, Vol. 62, No. 46, 2014, p. 11279-11288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction. / Galougahi, Keyvan Karimi; Liu, Chia-Chi; Gentile, Carmine; Kok, Cindy; Nunez, Andrea; Garcia, Alvaro; Fry, Natasha A S; Davies, Michael Jonathan; Hawkins, Clare Louise; Rasmussen, Helge H; Figtree, Gemma A.

    In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease, Vol. 3, No. 2, 2014, p. e000731.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205