Michael Jonathan Davies

Michael Jonathan Davies

Professor

  • Inflammation, Metabolism and Oxidation

    Blegdamsvej 3, 2200 København N, 12.6, Building: 30

    Phone: +45 35 33 69 77Mobile: +45 23 64 94 45

  1. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides : formation of chloramines and nitrogen-centered radicals. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 15, No. 1, 01.2002, p. 83-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Reaction of protein chloramines with DNA and nucleosides : evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation. / Hawkins, Clare Louise; Pattison, David I; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 365, No. Pt 3, 01.08.2002, p. 605-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation. / Hawkins, Clare Louise; Pattison, David I; Stanley, Naomi R; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 416, No. 3, 15.12.2008, p. 441-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Inactivation of protease inhibitors and lysozyme by hypochlorous acid : role of side-chain oxidation and protein unfolding in loss of biological function. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 18, No. 10, 10.2005, p. 1600-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 39, No. 7, 01.10.2005, p. 900-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Quantification of protein modification by oxidants. / Hawkins, Clare Louise; Morgan, Philip E; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 46, No. 8, 15.04.2009, p. 965-88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins. / Hawkins, Clare Louise; Rees, Martin D; Davies, Michael Jonathan.

    In: FEBS letters, Vol. 510, No. 1-2, 02.01.2002, p. 41-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 18, No. 11, 11.2005, p. 1669-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Detection and characterisation of radicals in biological materials using EPR methodology. / Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: B B A - Reviews on Cancer, Vol. 1840, No. 2, 02.2014, p. 708-21.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins. / Hazell, L J; Davies, Michael Jonathan; Stocker, R.

    In: Biochemical Journal, Vol. 339 ( Pt 3), 1999, p. 489-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Benzoyl peroxide-induced damage to DNA and its components : direct evidence for the generation of base adducts, sugar radicals, and strand breaks. / Hazlewood, C; Davies, Michael Jonathan.

    In: Archives of Biochemistry and Biophysics, Vol. 332, No. 1, 01.08.1996, p. 79-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins : a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains. / Headlam, H A; Mortimer, A; Easton, C J; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 13, No. 11, 11.2000, p. 1087-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones. / Headlam, Henrietta A; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 32, No. 11, 01.06.2002, p. 1171-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals. / Headlam, Henrietta A; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 34, No. 1, 01.01.2003, p. 44-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Markers of protein oxidation : different oxidants give rise to variable yields of bound and released carbonyl products. / Headlam, Henrietta A; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 36, No. 9, 2004, p. 1175-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides. / Headlam, Henrietta A; Gracanin, Michelle; Rodgers, Kenneth J; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 40, No. 9, 01.05.2006, p. 1539-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Exploring oxidative modifications of tyrosine : An update on mechanisms of formation, advances in analysis and biological consequences. / Houée-Lévin, C; Bobrowski, K; Horakova, L; Karademir, B; Schöneich, C; Davies, Michael Jonathan; Spickett, C M.

    In: Free Radical Research, Vol. 49, No. 4, 04.2015, p. 347-73.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins : [Meeting Abstract]. / Ignasiak-Kciuk, Marta; Shashikadze, Bachuki; Frackowiak, Kamil; Gamon, Luke F.; Davies, Michael J.; Marciniak, Bronislaw.

    In: Free Radical Biology and Medicine, Vol. 139, No. S1, 89, 2019, p. S30-S30.

    Research output: Contribution to journalConference articleResearchpeer-review

  19. Published

    Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space. / Indo, Hiroko P; Majima, Hideyuki J; Terada, Masahiro; Suenaga, Shigeaki; Tomita, Kazuo; Yamada, Shin; Higashibata, Akira; Ishioka, Noriaki; Kanekura, Takuro; Nonaka, Ikuya; Hawkins, Clare Louise; Davies, Michael J; Clair, Daret K St; Mukai, Chiaki.

    In: Scientific Reports, Vol. 6, 39015, 16.12.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function. / Indo, Hiroko P.; Hawkins, Clare L; Nakanishi, Ikuo; Matsumoto, Ken-Ichiro; Matsui, Hirofumi; Suenaga, Shigeaki; Davies, Michael J; St Clair, Daret K; Ozawa, Toshihiko; Majima, Hideyuki J.

    Pharmacology of Mitochondria. Vol. 240 Springer, 2017. p. 439-456 (Handbook of Experimental Pharmacology, Vol. 240).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  21. Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion. / Indo, Hiroko P.; Matsui, Hirofumi; Chen, Jing; Zhu, Haining; Hawkins, Clare Louise; Davies, Michael J.; Yarana, Chontida; Clair, Daret K St; Majima, Hideyuki J.

    In: Journal of Clinical Biochemistry and Nutrition, Vol. 57, No. 1, 01.07.2015, p. 13-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Myoglobin-induced oxidative damage : evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants. / Irwin, J A; Ostdal, H; Davies, Michael Jonathan.

    In: Archives of Biochemistry and Biophysics, Vol. 362, No. 1, 01.02.1999, p. 94-104.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function : A Contributing Factor to Macrophage Dysfunction in Atherosclerosis? / Ismael, Fahd O; Barrett, Tessa J; Sheipouri, Diba; Brown, Bronwyn E; Davies, Michael J; Hawkins, Clare Louise.

    In: P L o S One, Vol. 11, No. 12, e0168844, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL) : implications for foam cell formation in atherosclerosis. / Ismael, Fahd O; Proudfoot, Julie M; Brown, Bronwyn E; van Reyk, David M; Croft, Kevin D; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Archives of Biochemistry and Biophysics, Vol. 573, 05.2015, p. 40-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Competitive kinetics as a tool to determine rate constants for reduction of ferrylmyoglobin by food components. / Jongberg, Sisse; Lund, Marianne Nissen; Pattison, David I.; Skibsted, Leif Horsfelt; Davies, Michael Jonathan.

    In: Food Chemistry, Vol. 199, 2016, p. 36-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Competitive reduction of perferrylmyoglobin radicals by protein thiols and plant phenols. / Jongberg, Sisse; Lametsch, Marianne Lund; Skibsted, Leif Horsfelt; Davies, Michael Jonathan.

    In: Journal of Agricultural and Food Chemistry, Vol. 62, No. 46, 2014, p. 11279-11288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}. / Juhl, Pernille; Bomdesen, Sandie; Bay-Jensen, Anne-Christine; Karsdal, Morten; Davies, Michael Jonathan; Siebuhr, Anne Sofie.

    In: Annals of the Rheumatic Diseases, Vol. 78, No. S2, THU0335, 2019, p. 448-449.

    Research output: Contribution to journalConference articleResearch

  28. Biomarkers of oxidative stress study V : ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine. / Kadiiska, Maria B; Basu, Samar; Brot, Nathan; Cooper, Christopher; Saari Csallany, A; Davies, Michael Jonathan; George, Magdalene M; Murray, Dennis M; Jackson Roberts, L; Shigenaga, Mark K; Sohal, Rajindar S; Stocker, Roland; Van Thiel, David H; Wiswedel, Ingrid; Hatch, Gary E; Mason, Ronald P.

    In: Free Radical Biology & Medicine, Vol. 61, 08.2013, p. 408-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides. / Kajer, Tracey B; Fairfull-Smith, Kathryn E; Yamasaki, Toshihide; Yamada, Ken-ichi; Fu, Shanlin; Bottle, Steven E; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 70, 05.2014, p. 96-105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Reactivity of disulfide bonds is markedly affected by structure and environment : implications for protein modification and stability. / Karimi, Maryam; Ignasiak, Marta T; Chan, Bun; Croft, Anna K; Radom, Leo; Schiesser, Carl H; Pattison, David I; Davies, Michael J.

    In: Scientific Reports, Vol. 6, 38572, 12.12.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Computational design of effective, bioinspired HOCl antioxidants : the role of intramolecular Cl+ and H+ shifts. / Karton, Amir; O'Reilly, Robert J; Pattison, David I; Davies, Michael Jonathan; Radom, Leo.

    In: Journal of the American Chemical Society, Vol. 134, No. 46, 21.11.2012, p. 19240-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Mechanistic view of iodide in oxidative stress : [Meeting Abstract]. / Kciuk, Marta Ignasiak; Davies, Michael Jonathan; Marciniak, Bronislaw.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-254, 2018, p. S122-S122.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  33. Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid. / Kennett, Eleanor C; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 45, No. 5, 01.09.2008, p. 716-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Mechanisms and consequences of oxidative damage to extracellular matrix. / Kennett, Eleanor C; Chuang, Christine Y; Degendorfer, Georg; Whitelock, John M; Davies, Michael Jonathan.

    In: Biochemical Society Transactions, Vol. 39, No. 5, 10.2011, p. 1279-87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid : evidence for a hydroxyl-radical-like mechanism. / Kennett, Eleanor C; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 42, No. 8, 15.04.2007, p. 1278-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner : implications for peroxynitrite-mediated damage at sites of inflammation. / Kennett, Eleanor C; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 47, No. 4, 15.08.2009, p. 389-400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains. / Kennett, Eleanor C; Rees, Martin D; Malle, Ernst; Hammer, Astrid; Whitelock, John M; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 49, No. 2, 15.07.2010, p. 282-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017). / Khramtsov, Valery V.; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 52, No. 3, 2018, p. 305-306.

    Research output: Contribution to journalEditorialResearch

  39. Published

    Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes : Baseline data from the DESMOND randomized controlled trial. / Khunti, K.; Skinner, T. C.; Heller, S.; Carey, M. E.; Dallosso, H. M.; Davies, M. J.

    In: Diabetic Medicine, Vol. 25, No. 12, 01.12.2008, p. 1454-1461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus : Three year follow-up of a cluster randomised controlled trial in primary care. / Khunti, Kamlesh; Gray, Laura J.; Skinner, Timothy; Carey, Marian E.; Realf, Kathryn; Dallosso, Helen; Fisher, Harriet; Campbell, Michael; Heller, Simon; Davies, Melanie J.

    In: BMJ (Online), Vol. 344, No. 7860, e2333, 09.06.2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans : A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study. / Khunti, Kamlesh; Taub, Nick; Tringham, Jennifer; Jarvis, Janet; Farooqi, Azhar; Skinner, T. Chas; Davies, Melanie J.

    In: Primary Care Diabetes, Vol. 4, No. 1, 01.04.2010, p. 25-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice. / Kim, Christine H. J.; Mitchell, James B.; Bursill, Christina A.; Sowers, Anastasia L.; Thetford, Angela; Cook, John A.; van Reyk, David M.; Davies, Michael J.

    In: Atherosclerosis, Vol. 240, No. 1, 05.2015, p. 234-241.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein. / Knott, Heather M; Baoutina, Anna; Davies, Michael Jonathan; Dean, Roger T.

    In: Archives of Biochemistry and Biophysics, Vol. 400, No. 2, 15.04.2002, p. 223-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles. / Knott, Heather M; Brown, Bronwyn E; Davies, Michael Jonathan; Dean, Roger T.

    In: European Journal of Biochemistry, Vol. 270, No. 17, 09.2003, p. 3572-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations. / Koelsch, Maud; Mallak, Roger; Graham, Garry G; Kajer, Tracey; Milligan, Marian K; Nguyen, Ly Q; Newsham, Dawn W; Keh, Jeremy S; Kettle, Anthony J; Scott, Kieran F; Ziegler, John B; Pattison, David I; Fu, Shanlin; Hawkins, Clare Louise; Rees, Martin D; Davies, Michael Jonathan.

    In: Biochemical Pharmacology, Vol. 79, No. 8, 15.04.2010, p. 1156-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Regulation and control of nitric oxide (NO) in macrophages : Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1. / Kovacevic, Zaklina; Sahni, Sumit; Lok, K.H.; Davies, M J; Wink, D A; Richardson, Des R.

    In: B B A - Reviews on Cancer, Vol. 1861, No. 5 Pt A, 05.2017, p. 995-999.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin. / Krämer, Anna C; Torreggiani, Armida; Davies, Michael J.

    In: Journal of Agricultural and Food Chemistry, Vol. 65, No. 47, 2017, p. 10258-10269.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Key role of cysteine residues and sulfenic acids in thermal- and H2O2-mediated modification of β-lactoglobulin. / Krämer, Anna Carola; Thulstrup, Peter Waaben; Lund, Marianne Nissen; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 97, No. 8, 2016, p. 544–555.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Key role of cysteine residues in thermal- and H2O2-mediated modification of beta-lactoglobulin. / Krämer, Anna Carola; Thulstrup, Peter Waaben; Lund, Marianne Nissen; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 96, No. Suppl. 1, 2016, p. S16.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals. / Lam, Magdalena A; Pattison, David I; Bottle, Steven E; Keddie, Daniel J; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 21, No. 11, 11.2008, p. 2111-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links. / Lametsch, Marianne Lund; Luxford, Catherine; Skibsted, Leif Horsfelt; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 410, No. 3, 2008, p. 565-574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages. / Lane, Amanda E; Tan, Joanne T M; Hawkins, Clare Louise; Heather, Alison K; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 430, No. 1, 15.08.2010, p. 161-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals. / Leinisch, Fabian; Mariotti, Michele; Hagglund, Per; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 126, 10.2018, p. 73-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues. / Leinisch, Fabian; Mariotti, Michele; Rykaer, Martin; López-Alarcón, Camilo; Hägglund, Per; Davies, Michael J.

    In: Free Radical Biology & Medicine, Vol. 112, 11.2017, p. 240-252.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease. / Leung, Christopher; Herath, Chandana B.; Jia, Zhiyuan; Andrikopoulos, Sof; Brown, Bronwyn E.; Davies, Michael J.; Rivera, Leni R.; Furness, John B.; Forbes, Josephine M.; Angus, Peter W.

    In: World Journal of Gastroenterology, Vol. 22, No. 35, 21.09.2016, p. 8026-8040.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Quinone-induced protein modifications : kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins. / Li, Yuting; Jongberg, Sisse; Andersen, Mogens Larsen; Davies, Michael Jonathan; Lund, Marianne Nissen.

    In: Free Radical Biology & Medicine, Vol. 97, 2016, p. 148-157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Protein oxidation and ageing. / Linton, S; Davies, Michael Jonathan; Dean, R T.

    In: Experimental Gerontology, Vol. 36, No. 9, 09.2001, p. 1503-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells. / Lloyd, Mitchell M; Grima, Michael A; Rayner, Benjamin S; Hadfield, Katrina A; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Free Radical Biology & Medicine, Vol. 65, 12.2013, p. 1352-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid. / Lloyd, Mitchell M; van Reyk, David M; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Biochemical Journal, Vol. 414, No. 2, 01.09.2008, p. 271-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling. / Lord, Megan S; Chuang, Christine Y; Melrose, James; Davies, Michael Jonathan; Iozzo, Renato V; Whitelock, John M.

    In: Matrix Biology, Vol. 35, 04.2014, p. 112-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Nitration alters laminin polymerization : [Meeting Abstract]. / Lorentzen, Lasse; Davies, Michael.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-271, 2018, p. S127-S127.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  62. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications. / Lorentzen, Lasse G.; Chuang, Christine Y.; Rogowska-Wrzesinska, Adelina; Davies, Michael J.

    In: Redox Biology, Vol. 24, UNSP 101226, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages. / Love, D; Barrett, T.J.; White, M.Y.; Cordwell, S.J.; Davies, Michael Jonathan; Hawkins, Clare Louise.

    In: Free Radical Biology & Medicine, Vol. 94, 2016, p. 88-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The immunoproteasome is induced by cytokines and regulates apoptosis in human islets. / Lundh, Morten; Bugliani, Marco; Dahlby, Tina; Chou, Danny Hung-Chieh; Wagner , Bridget; Ghiasi, Seyed Mojtaba; De Tata, Vincenzo; Chen, Zhifei; Lund, Marianne Nissen; Davies, Michael Jonathan; Marchetti, Piero; Mandrup-Poulsen, Thomas.

    In: Journal of Endocrinology, Vol. 233, No. 3, 2017, p. 369-379.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA. / Luxford, C; Dean, R T; Davies, Michael Jonathan.

    In: Chemical Research in Toxicology, Vol. 13, No. 7, 07.2000, p. 665-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA. / Luxford, C; Morin, B; Dean, R T; Davies, Michael Jonathan.

    In: Biochemical Journal, Vol. 344 Pt 1, 15.11.1999, p. 125-34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Induction of DNA damage by oxidised amino acids and proteins. / Luxford, Catherine; Dean, Roger T; Davies, Michael Jonathan.

    In: Biogerontology, Vol. 3, No. 1-2, 2002, p. 95-102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima. / Mai, Kelly; Smith, Nicholas C; Feng, Zhi-Ping; Katrib, Marilyn; Slapeta, Jan; Slapetova, Iveta; Wallach, Michael G; Luxford, Catherine; Davies, Michael Jonathan; Zhang, Xuecheng; Norton, Raymond S; Belli, Sabina I.

    In: International Journal for Parasitology (Online), Vol. 41, No. 11, 09.2011, p. 1157-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Chasing Great Paths of Helmut “Oxidative Stress” Sies. / Majima, H.; Indo, H.; Nakanishi, I.; Suenaga, S.; Matsumoto, K.-I.; Matsui, H.; Minamiyami, Y.; Ichikawa, H.; Yen, H.-C.; Hawkins, Clare; Davies, Michael Jonathan; Ozawa, T.; St. Clair, D.

    In: Archives of Biochemistry and Biophysics, Vol. 595, 2016, p. 54-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid. / Malle, Ernst; Marsche, Gunther; Arnhold, Jürgen; Davies, Michael Jonathan.

    In: B B A - Reviews on Cancer, Vol. 1761, No. 4, 04.2006, p. 392-415.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation. / Mariotti, Michele; Leinisch, Fabian; Leeming, Diana Julie; Svensson, Birte; Davies, Michael J.; Hagglund, Per.

    In: Journal of Proteome Research, Vol. 17, No. 6, 2018, p. 2017-2027.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Absence of synproportionation between oxy and ferryl leghemoglobin. off. / Mathieu, C; Swaraj, K; Davies, Michael Jonathan; Trinchant, J C; Puppo, A.

    In: Free Radical Research, Vol. 27, No. 2, 08.1997, p. 165-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Direct detection of radicals in intact soybean nodules : presence of nitric oxide-leghemoglobin complexes. / Mathieu, C; Moreau, S; Frendo, P; Puppo, A; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 24, No. 7-8, 1998, p. 1242-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation. / Mertens, K; Lowes, D A; Webster, N R; Talib, J; Hall, L; Davies, Michael J.; Beattie, J H; Galley, H F.

    In: British Journal of Anaesthesia, Vol. 114, No. 6, 2015, p. 990-999.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage. / Mizdrak, Jasminka; Hains, Peter G; Truscott, Roger J W; Jamie, Joanne F; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 44, No. 6, 15.03.2008, p. 1108-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function : possible links between diabetes and atherosclerosis. / Moheimani, Fatemeh; Morgan, Philip E; van Reyk, David M; Davies, Michael Jonathan.

    In: B B A - Reviews on Cancer, Vol. 1802, No. 6, 06.2010, p. 561-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins. / Moheimani, Fatemeh; Tan, Joanne T M; Brown, Bronwyn E; Heather, Alison K; van Reyk, David M; Davies, Michael Jonathan.

    In: Journal of Diabetes Research, Vol. 2011, 2011, p. 851280.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations : a potential contributory factor in diabetes-associated atherosclerosis. / Moheimani, Fatemeh; Kim, Christine H J; Rahmanto, Aldwin Suryo; van Reyk, David M; Davies, Michael Jonathan.

    In: Atherosclerosis, Vol. 223, No. 1, 07.2012, p. 144-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Reaction of ferric leghemoglobin with H2O2 : formation of heme-protein cross-links and dimeric species. / Moreau, S; Davies, M J; Puppo, A.

    In: Biochimica et biophysica acta, Vol. 1251, No. 1, 16.08.1995, p. 17-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage. / Moreau, S; Davies, Michael Jonathan; Mathieu, C; Hérouart, D; Puppo, A.

    In: The Journal of Biological Chemistry, Vol. 271, No. 51, 20.12.1996, p. 32557-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase. / Morgan, P E; Laura, R P; Maki, R A; Reynolds, W F; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 49, No. 6, 27.03.2015, p. 743-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus. / Morgan, Philip E; Sturgess, Allan D; Davies, Michael Jonathan.

    In: Arthritis & Rheumatism, Vol. 52, No. 7, 07.2005, p. 2069-79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients. / Morgan, Philip E; Sturgess, Allan D; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 43, No. 2, 02.2009, p. 117-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products. / Morgan, Philip E; Dean, Roger T; Davies, Michael Jonathan.

    In: Archives of Biochemistry and Biophysics, Vol. 403, No. 2, 15.07.2002, p. 259-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes. / Morgan, Philip E; Sheahan, Pamela J; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 61, 08.2013, p. 229-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack. / Morgan, Philip E; Dean, Roger T; Davies, Michael Jonathan.

    In: European Journal of Biochemistry, Vol. 269, No. 7, 04.2002, p. 1916-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen. / Morgan, Philip E; Dean, Roger T; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 36, No. 4, 15.02.2004, p. 484-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline. / Morgan, Philip E; Pattison, David I; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 52, No. 2, 15.01.2012, p. 328-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins. / Morgan, Philip E; Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 45, No. 9, 01.11.2008, p. 1279-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal. / Morgan, Philip E; Sheahan, Pamela J; Davies, Michael Jonathan.

    In: PloS one, Vol. 9, No. 1, e86564, 2014.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis. / Morgan, Philip E; Sturgess, Allan D; Hennessy, Annemarie; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 41, No. 12, 12.2007, p. 1301-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase. / Morgan, Philip E; Pattison, David I; Talib, Jihan; Summers, Fiona A; Harmer, Jason A; Celermajer, David S; Hawkins, Clare Louise; Davies, Michael Jonathan.

    In: Free Radical Biology & Medicine, Vol. 51, No. 9, 01.11.2011, p. 1815-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage. / Morin, B; Davies, Michael Jonathan; Dean, R T.

    In: Biochemical Journal, Vol. 330 ( Pt 3), 15.03.1998, p. 1059-67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation. / Morin, B; Bubb, W A; Davies, Michael Jonathan; Dean, R T; Fu, S.

    In: Chemical Research in Toxicology, Vol. 11, No. 11, 11.1998, p. 1265-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Analysis of aliphatic amino acid alcohols in oxidized proteins. / Morin, Bénédicte; Fu, Shanlin; Wang, Hongjie; Davies, Michael Jonathan; Dean, Roger T.

    In: Methods in molecular biology (Clifton, N.J.), Vol. 186, 2002, p. 101-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte. / Murphy, P G; Davies, Michael Jonathan; Columb, M O; Stratford, N.

    In: British Journal of Anaesthesia, Vol. 76, No. 4, 04.1996, p. 536-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction. / Nedoboy, P E; Morgan, P E; Mocatta, T J; Richards, A M; Winterbourn, C C; Davies, Michael Jonathan.

    In: Free Radical Research, Vol. 48, No. 10, 10.2014, p. 1256-66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress. / Ng, Hooi Hooi; Leo, Chen Huei; O'Sullivan, Kelly; Alexander, Stefanie-Ann; Davies, Michael J; Schiesser, Carl H; Parry, Laura J.

    In: Biochemical Pharmacology, Vol. 128, 03.2017, p. 34-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin. / Nielsen, Line R.; Lund, Marianne N.; Davies, Michael J.; Nielsen, Jacob H.; Nielsen, Søren B.

    In: International Dairy Journal, Vol. 79, 2018, p. 52-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I. / Nobécourt, Estelle; Tabet, Fatiha; Lambert, Gilles; Puranik, Rajesh; Bao, Shisan; Yan, Ling; Davies, Michael Jonathan; Brown, Bronwyn E; Jenkins, Alicia J; Dusting, Gregory J; Bonnet, David J; Curtiss, Linda K; Barter, Philip J; Rye, Kerry-Anne.

    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 30, No. 4, 04.2010, p. 766-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205