Lene Juel Rasmussen
Professor
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mHealth intervention for carers of individuals with a history of stroke: Heuristic evaluation and user perspectives
Lobo, E. H., Kensing, Finn, Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Islam, S. M. S., Grundy, J. & Abdelrazek, M., 2022, In: Digital Health. 8, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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mHealth applications to support caregiver needs and engagement during stroke recovery: A content review
Lobo, E. H., Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J. & Abdelrazek, M., 2021, In: Research in Nursing and Health. 44, 1, p. 213-225Research output: Contribution to journal › Review › Research › peer-review
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Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study
The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Utilization of social media communities for caregiver information support in stroke recovery: An analysis of content and interactions
Lobo, E. H., Johnson, T., Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Hosking, S. M., Page, A. T., Livingston, P. M., Islam, S. M. S., Grundy, J. & Abdelrazek, M., 2022, In: PLoS ONE. 17, 1, 19 p., e0262919.Research output: Contribution to journal › Journal article › Research › peer-review
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Understanding the Methodological Issues and Solutions in the Research Design of Stroke Caregiving Technology
Lobo, E. H., Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J., Abdelrazek, M. & Kensing, Finn, 2021, In: Frontiers in Public Health. 9, 7 p., 647249.Research output: Contribution to journal › Journal article › Research › peer-review
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Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome
Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In: Genetics in Medicine. 22, p. 847–856Research output: Contribution to journal › Journal article › Research › peer-review
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Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia
Bundgaard, A., Qvortrup, Klaus, Rasmussen, Lene Juel & Fago, A., 2019, In: Journal of Experimental Biology. 222, 11, 9 p., jeb200410.Research output: Contribution to journal › Journal article › Research › peer-review
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Thymidine kinase 1 deficient cells show increased survival rate after UV-induced DNA damage
Skovgaard, T., Rasmussen, Lene Juel & Munch-Petersen, B., 2010, In: Nucleosides, Nucleotides and Nucleic Acids. 29, 4-6, p. 347-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of mitochondrial dysfunction in the progression of Alzheimer’s disease
Desler, Claus, Lillenes, M. S., Tønjum, T. & Rasmussen, Lene Juel, 2018, In: Current Medicinal Chemistry. 25, 40, p. 5578 - 5587Research output: Contribution to journal › Review › Research › peer-review
The role of mitochondrial dNTP levels in cells with reduced TK2 activity
Desler, C., Munch-Petersen, B. & Rasmussen, Lene Juel, 2006, In: Nucleosides, nucleotides & nucleic acids. 25, 9-11, p. 1171-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of RecQ helicases in non-homologous end-joining
Keijzers, G., Maynard, S., Shamanna, R. A., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2014, In: Critical Reviews in Biochemistry and Molecular Biology. 49, 6, p. 463-472 10 p.Research output: Contribution to journal › Review › Research › peer-review
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The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms
Jakobsen, Emil, Lange, S. C., Andersen, Jens Velde, Desler, Claus, Kihl, H. F., Hohnholt, M., Stridh, M. H., Rasmussen, Lene Juel, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, 2018, In: Biochemical Pharmacology. 155, p. 92-101 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of mitochondrial DNA in aging and cancer
Desler, Claus, Espersen, M. L. M., Singh, K. K. & Rasmussen, Lene Juel, 30 Mar 2011, In: Journal of Aging Research. 2011, p. 407536Research output: Contribution to journal › Journal article › Research › peer-review
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The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients
Jensen, M. B., Dunn, C. A., Keijzers, G., Kulikowicz, T., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2012, In: Aging. 4, 11, p. 790-802 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism
Desler, Claus, Lykke, A. & Rasmussen, Lene Juel, 1 Jan 2010, In: Journal of Nucleic Acids. 2010Research output: Contribution to journal › Journal article › Research › peer-review
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The challenges of human population ageing
Sander, M., Oxlund, Bjarke, Jespersen, Astrid Pernille, Krasnik, Allan, Mortensen, Erik Lykke, Westendorp, Rudi GJ & Rasmussen, Lene Juel, Mar 2015, In: Age and Ageing. 44, 2, p. 185-7 3 p.Research output: Contribution to journal › Journal article › Communication
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The cGAS-STING signaling pathway is modulated by urolithin A
Madsen, Helena Borland, Park, J. H., Chu, X., Hou, Y., Li, Zhiquan, Rasmussen, Lene Juel, Croteau, D. L., Bohr, Vilhelm & Akbari, M., 2024, In: Mechanisms of Ageing and Development. 217, 11 p., 111897.Research output: Contribution to journal › Journal article › Research › peer-review
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The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.Research output: Contribution to journal › Journal article › Research › peer-review
The LipB protein is a negative regulator of dam gene expression in Escherichia coli
Vaisvila, R., Rasmussen, Lene Juel, Løbner-Olesen, Anders, von Freiesleben, U. & Marinus, M. G., 2000, In: Biochimica et Biophysica Acta, Gene Structure and Expression. 1494, 1-2, p. 43-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
Madsen, Helena Borland, Pease, L. I., Scanlan, R. L., Akbari, M., Rasmussen, Lene Juel, Shanley, D. P. & Bohr, Vilhelm, 2023, In: Frontiers in Aging Neuroscience. 15, 17 p., 1290681.Research output: Contribution to journal › Journal article › Research › peer-review
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Technology-based support for stroke caregiving: A rapid review of evidence
Lobo, E. H., Abdelrazek, M., Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J., Islam, S. M. S. & Frølich, Anne, 2022, In: Journal of Nursing Management. 30, 8, p. 3700-3713 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TIP60 in aging and neurodegeneration
Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.Research output: Contribution to journal › Review › Research › peer-review
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Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing
Guimera, A. M., Clark, P., Wordsworth, J., Anugula, Sharath, Rasmussen, Lene Juel & Shanley, D. P., 2022, In: Experimental Gerontology. 166, 9 p., 111889.Research output: Contribution to journal › Review › Research › peer-review
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Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.Research output: Contribution to journal › Journal article › Research › peer-review
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Societal need for interdisciplinary ageing research
Cherbuin, N., Lijima, K., Kalula, S., Malhotrad, R., Rasmussen, Lene Juel, Chan, A., Lafortune, L., Harper, S., Zheng, X., Lindeman, D., Walsh, E., Hussain, R., Burns, R., Kristiansen, Maria, Sugawara, I., Son, B., Tanaka, T., Buckner, S., Hoffman, J. & Combrinck, M., 25 Feb 2021, In: Biomedicine Hub. 6, 1, p. 42-47 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simvastatin improves mitochondrial respiration in peripheral blood cells
Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.Research output: Contribution to journal › Journal article › Research › peer-review
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Salidroside promotes healthy longevity by interfering with HSP90 activity
Zhang, J., Li, Zhiquan, Song, J., Zhou, L., Chen, X., Ge, W., Dong, T., Luo, Y., Mao, T., Li, Z., Tan, D., Rasmussen, Lene Juel, Bohr, Vilhelm, Tong, X. & Dai, F., 2024, In: GeroScience. 46, p. 1641–1655 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Fakouri, N. B., Durhuus, J. A., Regnell, C. E., Angleys, M., Desler, Claus, Hasan-Olive, M., Martin-Pardillos, A., Tsaalbi-Shtylik, A., Thomsen, Kirsten Joan, Lauritzen, Martin, Bohr, Vilhelm, de Wind, N., Bergersen, L. H. & Rasmussen, Lene Juel, 2017, In: Scientific Reports. 7, 14 p., 12480.Research output: Contribution to journal › Journal article › Research › peer-review
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Response to: Design of a core classification process for DNA mismatch repair variations of a priori unknown functional significance
Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Jun 2013, In: Human Mutation. 34, 6, p. 923-4 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Repair of DNA damage induced by anthanthrene, a polycyclic aromatic hydrocarbon (PAH) without bay or fjord regions
Desler, Claus, Johannessen, C. & Rasmussen, Lene Juel, 2009, In: Chemico-Biological Interactions. 177, 3, p. 212-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
Maynard, S., Keijzers, G., Gram, M., Desler, Claus, Bendix, L., Budtz-Joergensen, Esben, Molbo, Drude, Croteau, D. L., Osler, Merete, Stevnsner, T. V., Rasmussen, Lene Juel, Dela, Flemming, Avlund, K. & Bohr, Vilhelm, 30 Nov 2013, In: Aging. p. 850-864 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks
Lu, H., Shamanna, R. A., Keijzers, G., Anand, R., Rasmussen, Lene Juel, Cejka, P., Croteau, D. L. & Bohr, Vilhelm, 28 Jun 2016, In: Cell Reports. 16, 1, p. 161-173 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma
Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421Research output: Contribution to journal › Journal article › Research › peer-review
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Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations
Nielsen, S. V., Stein, Amelie, Dinitzen, A. B., Papaleo, E., Tatham, M. H., Poulsen, E. G., Kassem, M. M., Rasmussen, Lene Juel, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 19 Apr 2017, In: PLoS Genetics. 13, 4, 26 p., e1006739.Research output: Contribution to journal › Journal article › Research › peer-review
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Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future
Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Dec 2012, In: Human Mutation. 33, 12, p. 1617-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation
Desler, Claus, Durhuus, J. A., Hansen, T. L. L., Anugula, Sharath, Zelander, N. T., Bøggild, S. & Rasmussen, Lene Juel, 2022, In: Mitochondrion. 64, p. 73-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human lung epithelial cells and macrophages
Jantzen, K., Roursgaard, Martin, Desler, Claus, Loft, Steffen, Rasmussen, Lene Juel & Møller, Peter, Nov 2012, In: Mutagenesis. 27, 6, p. 693-701 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation
Toft-Kehler, A. K., Gurubaran, I. S., Desler, Claus, Rasmussen, Lene Juel, Jensen, Dorte Skytt & Kolko, Miriam, May 2016, In: Investigative Ophthalmology & Visual Science. 57, 6, p. 2721-2728Research output: Contribution to journal › Journal article › Research › peer-review
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Nuclear translocation contributes to regulation of DNA excision repair activities
Knudsen, N. Ø., Andersen, S. D., Lützen, A., Nielsen, Finn Cilius & Rasmussen, Lene Juel, 2009, In: DNA Repair. 8, 6, p. 682-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1)
Knudsen, N. Ø., Nielsen, Finn Cilius, Vinther, L., Bertelsen, R., Holten-Andersen, S., Liberti, S. E., Hofstra, R., Kooi, K. & Rasmussen, Lene Juel, 2007, In: Nucleic Acids Research. 35, 8, p. 2609-19 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel growth rate control of dam gene expression in Escherichia coli
Rasmussen, Lene Juel, Marinus, M. G. & Løbner-Olesen, Anders, 1994, In: Molecular Microbiology. 12, 4, p. 631-638 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Novel DNA mismatch-repair activity involving YB-1 in human mitochondria
de Souza-Pinto, N. C., Mason, P. A., Hashiguchi, K., Weissman, L., Tian, J., Guay, D., Lebel, M., Stevnsner, T. V., Rasmussen, Lene Juel & Bohr, V. A., 2009, In: DNA Repair. 8, 6, p. 704-19 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary
Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, , 2022, In: Aging. 14, 16, p. 6829-6839 11 p.Research output: Contribution to journal › Review › Research › peer-review
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Natural selection of mitochondria during somatic lifetime promotes healthy aging
Rodell, A., Rasmussen, Lene Juel, Bergersen, L. H., Singh, K. K. & Gjedde, Albert, 2013, In: Frontiers in Neuroenergetics. 5, p. 1-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nanomaterial-induced cell death in pulmonary and hepatic cells following exposure to three different metallic materials: The role of autophagy and apoptosis
Kermanizadeh, A., Jantzen, K., Ward, M. B., Durhuus, J. A., Rasmussen, Lene Juel, Loft, Steffen & Møller, Peter, Mar 2017, In: Nanotoxicology. 11, 2, p. 184-200 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules
Peeters, M. J. W., Aehnlich, P., Pizzella, A., Mølgaard, K., Seremet, T., Met, Özcan, Rasmussen, Lene Juel, thor Straten, P. & Desler, Claus, 2021, In: Frontiers in Immunology. 12, 718863.Research output: Contribution to journal › Journal article › Research › peer-review
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Mitochondrial oxidative phosphorylation capacity of cryopreserved cells
Lauridsen, P. E., Rasmussen, Lene Juel & Desler, Claus, 2019, In: Mitochondrion. 47, p. 47-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics
du Mee, D. J. M., Bak, M., Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In: Mitochondrion. 53, p. 255-259Research output: Contribution to journal › Journal article › Research › peer-review
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Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions
Bjerregaard, Victoria Alexandra, Schönewolf-Greulich, B., Rasmussen, Lene Juel, Desler, Claus & Tümer, Asuman Zeynep, 2020, In: Frontiers in Neurology. 11, 9 p., 163.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13558388
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Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
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Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells
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LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
Research output: Contribution to journal › Journal article › Research › peer-review
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