Lene Juel Rasmussen

Lene Juel Rasmussen

Managing director of centre, professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 1: Modifiable pathways of damage and repair in aging


  1. 2014
  2. Published

    Enterococcus faecalis Infection and Reactive Oxygen Species Down-Regulates the miR-17-92 Cluster in Gastric Adenocarcinoma Cell Culture. / Strickertsson, Jesper A B; Rasmussen, Lene Juel; Friis-Hansen, Lennart.

    In: Genes, Vol. 5, No. 3, 28.08.2014, p. 726-38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The role of RecQ helicases in non-homologous end-joining. / Keijzers, Guido; Maynard, Scott; Shamanna, Raghavendra A; Rasmussen, Lene Juel; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Critical Reviews in Biochemistry and Molecular Biology, Vol. 49, No. 6, 11.2014, p. 463-472.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli. / Bendtsen, Kristian Moss; Jensen, Martin Borch; May, Alfred; Rasmussen, Lene Juel; Trusina, Ala; Bohr, Vilhelm; Jensen, Mogens Høgh.

    In: European Biophysics Journal, Vol. 43, No. 10-11, 14.11.2014, p. 509-516.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2015
  6. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance. / Maynard, S; Keijzers, G; Hansen, Åse Marie; Osler, M; Molbo, D; Bendix, L; Møller, P; Loft, S; Moreno-Villanueva, M; Bürkle, A; Hvitby, Christina Poulsen; Schurman, S H; Stevnsner, Tinna V.; Rasmussen, L J; Avlund, K; Bohr, V A.

    In: Acta Physiologica (Print), Vol. 213, No. 1, 01.2015, p. 156-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published

    The challenges of human population ageing. / Sander, Miriam; Oxlund, Bjarke; Jespersen, Astrid; Krasnik, Allan; Mortensen, Erik Lykke; Westendorp, Rudi Gerardus Johannes; Rasmussen, Lene Juel.

    In: Age and Ageing, Vol. 44, No. 2, 03.2015, p. 185-7.

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice. / Lopez-Contreras, Andres J; Specks, Julia; Barlow, Jacqueline H; Ambrogio, Chiara; Madsen, Claus Desler; Vikingsson, Svante; Rodrigo-Perez, Sara; Green, Henrik; Rasmussen, Lene Juel; Murga, Matilde; Nussenzweig, André; Fernandez-Capetillo, Oscar.

    In: Genes & Development, Vol. 29, No. 7, 01.04.2015, p. 690-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures. / Keijzers, Guido; Bohr, Vilhelm A; Juel Rasmussen, Lene.

    In: Bioscience Reports, Vol. 35, No. 3, e00206, 25.04.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure. / Lauritzen, Knut H.; Kleppa, Liv; Aronsen, Jan Magnus; Eide, Lars; Carlsen, Harald; Haugen, Oyvind P.; Sjaastad, Ivar; Klungland, Arne; Rasmussen, Lene Juel; Attramadal, Havard; Storm-Mathisen, Jon; Bergersen, Linda H.

    In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 309, No. 3, 01.08.2015, p. H434-H449.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients. / Maynard, Scott; Hejl, Anne-Mette; Dinh, Tran Thuan Son; Keijzers, Guido; Hansen, Åse M; Madsen, Claus Desler; Moreno-Villanueva, Maria; Bürkle, Alexander; Rasmussen, Lene J; Waldemar, Gunhild; Bohr, Vilhelm A.

    In: Aging, Vol. 7, No. 10, 10.2015, p. 793-815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline. / Madsen, Claus Desler; Frederiksen, Jane H; Olsen, Maria Nathalie Angleys; Maynard, Scott; Keijzers, Guido; Fagerlund, Birgitte; Mortensen, Erik Lykke; Osler, Merete; Lauritzen, Martin; Bohr, Vilhelm A; Rasmussen, Lene Juel.

    In: Mitochondrion, Vol. 25, 11.2015, p. 34-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2016
  15. Published
  16. Published

    Approaches to diagnose DNA mismatch repair gene defects in cancer. / Peña-Diaz, Javier; Rasmussen, Lene Juel.

    In: DNA Repair, Vol. 38, 02.2016, p. 147-154.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation. / Toft-Kehler, Anne Katrine; Gurubaran, Iswariyaraja Sridevi; Madsen, Claus Desler; Rasmussen, Lene J.; Skytt, Dorte Marie; Kolko, Miriam.

    In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 6, 05.2016, p. 2721-2728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover. / Nygaard, Rie Harboe; Maynard, Scott; Schjerling, Peter; Kjær, Michael; Qvortrup, Klaus; Bohr, Vilhelm A; Rasmussen, Lene J; Jemec, Gregor B E; Heidenheim, Michael.

    In: Case Reports in Dermatology, Vol. 8, No. 1, 14.06.2016, p. 42-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks. / Lu, Huiming; Shamanna, Raghavendra A; Keijzers, Guido; Anand, Roopesh; Rasmussen, Lene Juel; Cejka, Petr; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Cell Reports, Vol. 16, No. 1, 28.06.2016, p. 161-173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Exonuclease 1 and its versatile roles in DNA repair. / Keijzers, Guido; Liu, Dekang; Rasmussen, Lene Juel.

    In: Critical Reviews in Biochemistry and Molecular Biology, Vol. 51, No. 6, 05.08.2016, p. 440–451.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression. / Syed, Salahuddin; Madsen, Claus Desler; Rasmussen, Lene J.; Schmidt, Kristina H.

    In: P L o S Genetics, Vol. 12, No. 12, e1006451, 12.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Interventions for age-related diseases : Shifting the paradigm. / Figueira, Inês; Fernandes, Adelaide; Mladenovic Djordjevic, Aleksandra; Lopez-Contreras, Andres; Henriques, Catarina M; Selman, Colin; Ferreiro, Elisabete; Gonos, Efstathios S; Trejo, José Luis; Misra, Juhi; Rasmussen, Lene Juel; Xapelli, Sara; Ellam, Timothy; Bellantuono, Ilaria.

    In: Mechanisms of Ageing and Development, Vol. 160, 12.2016, p. 69-92.

    Research output: Contribution to journalReviewResearchpeer-review

  23. 2017
  24. Published

    Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage. / Hopkinson, Branden M; Madsen, Claus Desler; Kalisz, Mark; Vestentoft, Peter Siig; Juel Rasmussen, Lene; Bisgaard, Hanne Cathrine.

    In: Oxidative Medicine and Cellular Longevity, Vol. 2017, 5080128, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1. / Vohra, Rupali; Gurubaran, Iswariyaraja Sridevi; Henriksen, Ulrik ; Bergersen, Linda Hildegaard; Rasmussen, Lene Juel; Desler, Claus; Skytt, Dorte Marie; Kolko, Miriam.

    In: Mitochondrion, Vol. 36, 2017, p. 52-59.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions. / Martín-Pardillos, Ana; Tsaalbi-Shtylik, Anastasia; Chen, Si; Lazare, Seka; Van Os, Ronald P.; Dethmers-Ausema, Albertina; Fakouri, Nima Borhan; Bosshard, Matthias; Aprigliano, Rossana; Van Loon, Barbara; Salvatori, Daniela C.F.; Hashimoto, Keiji; Van Der Spek, Celia Dingemanse; Moriya, Masaaki; Rasmussen, Lene Juel; De Haan, Gerald; Raaijmakers, Marc H.G.P.; De Wind, Niels.

    In: Blood, Vol. 130, No. 13, 2017, p. 1523-1534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours. / Rudolph, Christiane; Melau, Cecilie; Nielsen, John E.; Jensen, Kristina Vile; Liu, Dekang; Pena-Diaz, Javier; Meyts, Ewa Rajpert-De; Rasmussen, Lene Juel; Jorgensen, Anne.

    In: Cellular Oncology, Vol. 40, No. 4, 2017, p. 341-355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis. / Fakouri, Nima Borhan; Durhuus, Jon Ambaek; Regnell, Christine Elisabeth; Angleys, Maria; Desler, Claus; Hasan-Olive, Mahdi; Martin-Pardillos, Ana; Tsaalbi-Shtylik, Anastasia; Thomsen, Kirsten; Lauritzen, Martin; Bohr, Vilhelm A.; de Wind, Niels; Bergersen, Linda Hildegard; Rasmussen, Lene Juel.

    In: Scientific Reports, Vol. 7, 12480, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    EXO1 (Exonuclease 1). / Rasmussen, Lene Juel; Keijzers, Guido.

    Encyclopedia of Signaling Molecules . ed. / Sangdun Choi. New York : Springer, 2017.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

ID: 13558388