Lene Juel Rasmussen

Lene Juel Rasmussen

Professor

Member of:


  1. 2024
  2. Published

    Cognitive Function Is Associated with the Genetically Determined Efficiency of DNA Repair Mechanisms

    Cherbuin, N., Patel, H., Walsh, E. I., Ambikairajah, A., Burns, R., Brüstle, A. & Rasmussen, Lene Juel, 2024, In: Genes. 15, 2, 15 p., 153.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published
  4. Published

    The cGAS-STING signaling pathway is modulated by urolithin A

    Madsen, Helena Borland, Park, J. H., Chu, X., Hou, Y., Li, Zhiquan, Rasmussen, Lene Juel, Croteau, D. L., Bohr, Vilhelm & Akbari, M., 2024, In: Mechanisms of Ageing and Development. 217, 11 p., 111897.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Effects of reactive oxygen species and mitochondrial dysfunction on reproductive aging

    Song, J., Xiao, L., Zhang, Z., Wang, Y., Kouis, P., Rasmussen, Lene Juel & Dai, F., 2024, In: Frontiers in Cell and Developmental Biology. 12, 12 p., 1347286.

    Research output: Contribution to journalReviewpeer-review

  6. Published

    Salidroside promotes healthy longevity by interfering with HSP90 activity

    Zhang, J., Li, Zhiquan, Song, J., Zhou, L., Chen, X., Ge, W., Dong, T., Luo, Y., Mao, T., Li, Z., Tan, D., Rasmussen, Lene Juel, Bohr, Vilhelm, Tong, X. & Dai, F., 2024, In: GeroScience. 46, p. 1641–1655 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. 2023
  8. Published

    Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside

    Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    MRE11A: a novel negative regulator of human DNA mismatch repair

    Du, D., Yang, Y., Wang, G., Chen, L., Guan, X., Rasmussen, Lene Juel & Liu, D., 2023, bioRxiv, 34 p.

    Research output: Working paperPreprintResearch

  10. Published

    Detecting user experience issues from mHealth apps that support stroke caregiver needs: an analysis of user reviews

    Lobo, E. H., Abdelrazek, M., Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Islam, S. M. S., Kensing, Finn & Grundy, J., 2023, In: Frontiers in Public Health. 11, 9 p., 1027667.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Information, involvement, self-care and support—The needs of caregivers of people with stroke: A grounded theory approach

    Lobo, E. H., Frølich, Anne, Abdelrazek, M., Rasmussen, Lene Juel, Grundy, J., Livingston, P. M., Islam, S. M. S. & Kensing, Finn, 2023, In: PLoS ONE. 18, 1, p. 1-25 25 p., e0281198.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    The DNA repair enzyme, aprataxin, plays a role in innate immune signaling

    Madsen, Helena Borland, Pease, L. I., Scanlan, R. L., Akbari, M., Rasmussen, Lene Juel, Shanley, D. P. & Bohr, Vilhelm, 2023, In: Frontiers in Aging Neuroscience. 15, 17 p., 1290681.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain

    Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs

    Pinto, N. A., Abba, M. C., Laporte, L., Pérez Sáez, J. M., Blidner, A. G., Torres, N. I., Morales, R. M., Gatto, S. G., Bach, C. A., Veigas, F., García Rivello, H. J., Song, P., Frederiksen, J. H., Rasmussen, Lene Juel, Poirier, F., Croci, D. O., Sundblad, V., Rabinovich, G. A. & Cerliani, J. P., 2023, In: Cell Death and Differentiation. 30, p. pages906–921

    Research output: Contribution to journalJournal articlepeer-review

  15. 2022
  16. Published

    RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma

    Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation

    Desler, Claus, Durhuus, J. A., Hansen, T. L. L., Anugula, Sharath, Zelander, N. T., Bøggild, S. & Rasmussen, Lene Juel, 2022, In: Mitochondrion. 64, p. 73-81 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing

    Guimera, A. M., Clark, P., Wordsworth, J., Anugula, Sharath, Rasmussen, Lene Juel & Shanley, D. P., 2022, In: Experimental Gerontology. 166, 9 p., 111889.

    Research output: Contribution to journalReviewpeer-review

  19. Published

    Genomic instability and aging

    Li, Zhiquan, Anugula, Sharath & Rasmussen, Lene Juel, 2022, Aging: From Fundamental Biology to Societal Impact. Oliveira, P. J. & Malva, J. O. (eds.). Academic Press, p. 275-295 21 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. Published

    Technology-based support for stroke caregiving: A rapid review of evidence

    Lobo, E. H., Abdelrazek, M., Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J., Islam, S. M. S. & Frølich, Anne, 2022, In: Journal of Nursing Management. 30, 8, p. 3700-3713 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Utilization of social media communities for caregiver information support in stroke recovery: An analysis of content and interactions

    Lobo, E. H., Johnson, T., Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Hosking, S. M., Page, A. T., Livingston, P. M., Islam, S. M. S., Grundy, J. & Abdelrazek, M., 2022, In: PLoS ONE. 17, 1, 19 p., e0262919.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    mHealth intervention for carers of individuals with a history of stroke: Heuristic evaluation and user perspectives

    Lobo, E. H., Kensing, Finn, Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Islam, S. M. S., Grundy, J. & Abdelrazek, M., 2022, In: Digital Health. 8, 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

    The European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC), T. E. H. T. G. (. A. T. I. M. R. C. (., 2022, In: Hereditary Cancer in Clinical Practice. 20, 36.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

    Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, Fang, E. F., 2022, In: Aging. 14, 16, p. 6829-6839 11 p.

    Research output: Contribution to journalReviewpeer-review

  25. Published

    CNOT6: A Novel Regulator of DNA Mismatch Repair

    Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.

    Research output: Contribution to journalJournal articlepeer-review

  26. 2021
  27. Published

    Cytosolic self-DNA—A potential source of chronic inflammation in aging

    Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.

    Research output: Contribution to journalReviewpeer-review

  28. Published

    Societal need for interdisciplinary ageing research

    Cherbuin, N., Lijima, K., Kalula, S., Malhotrad, R., Rasmussen, Lene Juel, Chan, A., Lafortune, L., Harper, S., Zheng, X., Lindeman, D., Walsh, E., Hussain, R., Burns, R., Kristiansen, Maria, Sugawara, I., Son, B., Tanaka, T., Buckner, S., Hoffman, J. & Combrinck, M., 25 Feb 2021, In: Biomedicine Hub. 6, 1, p. 42-47 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

    Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    mHealth applications to support caregiver needs and engagement during stroke recovery: A content review

    Lobo, E. H., Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J. & Abdelrazek, M., 2021, In: Research in Nursing and Health. 44, 1, p. 213-225

    Research output: Contribution to journalReviewpeer-review

  31. Published

    Understanding the Methodological Issues and Solutions in the Research Design of Stroke Caregiving Technology

    Lobo, E. H., Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J., Abdelrazek, M. & Kensing, Finn, 2021, In: Frontiers in Public Health. 9, 7 p., 647249.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Caregiver Engagement in Stroke Care: Opportunities and Challenges in Australia and Denmark

    Lobo, E. H. S., Abdelrazek, M., Grundy, J., Kensing, F., Livingston, P. M., Rasmussen, Lene Juel, Islam, S. M. S. & Frølich, Anne, 2021, In: Frontiers in Public Health. 9, 6 p., 758808.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules

    Peeters, M. J. W., Aehnlich, P., Pizzella, A., Mølgaard, K., Seremet, T., Met, Özcan, Rasmussen, Lene Juel, thor Straten, Per & Desler, Claus, 2021, In: Frontiers in Immunology. 12, 718863.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes

    Subramanian, V., Rodemoyer, B., Shastri, V., Rasmussen, Lene Juel, Desler, Claus & Schmidt, K. H., 2021, In: Scientific Reports. 11, 2157.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study

    The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. 2020
  37. Published

    The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

    Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions

    Bjerregaard, V. A., Schönewolf-Greulich, B., Rasmussen, Lene Juel, Desler, Claus & Tümer, Asuman Zeynep, 2020, In: Frontiers in Neurology. 11, 9 p., 163.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome

    Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In: Genetics in Medicine. 22, p. 847–856

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

    Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Simvastatin improves mitochondrial respiration in peripheral blood cells

    Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

    Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In: BMC Cancer. 20, 1, 14 p., 349.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    TIP60 in aging and neurodegeneration

    Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.

    Research output: Contribution to journalReviewpeer-review

  44. Published

    ARDD 2020: from aging mechanisms to interventions

    Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, Gorbunova, V., Grey, A. D., He, W. W., Hoeijmakers, J., Hoffmann, Eva, Horvath, S., Houtkooper, R. H., Jensen, Majken Karoline, Jensen, M. B., Kane, A., Kassem, Moustapha Saad El-Deen, Keizer, P. D., Kennedy, B., Karsenty, G., Lamming, D. W., Lee, K. F., MacAulay, Nanna, Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, Andreas, Niedernhofer, L., Osborne, Brenna, Pak, H. H., Parkhitko, A., Raimundo, N., Rando, T. A., Rasmussen, Lene Juel, Reis, C., Riedel, C. G., Franco-Romero, A., Schumacher, B., Sinclair, D. A., Suh, Y., Taub, P. R., Toiber, D., Treebak, Jonas Thue, Valenzano, D. R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2020, In: Aging. 12, 24, p. 24486-24503 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

    Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

    Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics

    du Mee, D. J. M., Bak, M., Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In: Mitochondrion. 53, p. 255-259

    Research output: Contribution to journalJournal articlepeer-review

  48. 2019
  49. Published

    Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia

    Bundgaard, A., Qvortrup, Klaus, Rasmussen, Lene Juel & Fago, A., 2019, In: Journal of Experimental Biology. 222, 11, 9 p., jeb200410.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome

    Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, de Wind, N. & Tavtigian, S. V., 2019, In: Genetics in Medicine. 21, p. 1486–1496

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    From powerhouse to perpetrator—mitochondria in health and disease

    Fakouri, N. B., Hansen, T. L., Desler, Claus, Anugula, Sharath & Rasmussen, Lene Juel, 2019, In: Biology. 8, 2, 15 p., 35.

    Research output: Contribution to journalReviewpeer-review

  52. Published

    A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis

    Hasan-Olive, M. M., Lauritzen, K. H., Ali, M., Rasmussen, Lene Juel, Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Neurochemical Research. 44, 1, p. 22-37 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Mitochondrial oxidative phosphorylation capacity of cryopreserved cells

    Lauridsen, P. E., Rasmussen, Lene Juel & Desler, Claus, 2019, In: Mitochondrion. 47, p. 47-53 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    MERTK Acts as a costimulatory receptor on human cd8 t cells

    Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Desler, Claus & thor Straten, Per, 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  55. 2018
  56. Published

    The role of mitochondrial dysfunction in the progression of Alzheimer’s disease

    Desler, Claus, Lillenes, M. S., Tønjum, T. & Rasmussen, Lene Juel, 2018, In: Current Medicinal Chemistry. 25, 40, p. 5578 - 5587

    Research output: Contribution to journalReviewpeer-review

  57. Published

    The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms

    Jakobsen, Emil, Lange, S. C., Andersen, Jens Velde, Desler, Claus, Kihl, H. F., Hohnholt, M., Stridh, M. H., Rasmussen, Lene Juel, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, 2018, In: Biochemical Pharmacology. 155, p. 92-101 10 p.

    Research output: Contribution to journalJournal articlepeer-review

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