John Robert Couchman

John Robert Couchman

Professor emeritus


  1. Published

    Characterisation of stromal-cellular mechanotransduction through syndecan-4. / Hollosi, Peter; Grossi, Alberto; Couchman, John Robert.

    2010. Poster session presented at FECTS meeting, .

    Research output: Contribution to conferencePosterResearch

  2. Published

    On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis. / Holmborn, Katarina; Habicher, Judith; Kasza, Zsolt; Eriksson, Anna S; Filipek-Gorniok, Beata; Gopal, Sandeep; Couchman, John R; Ahlberg, Per E; Wiweger, Malgorzata; Spillmann, Dorothe; Kreuger, Johan; Ledin, Johan.

    In: The Journal of Biological Chemistry, Vol. 287, No. 40, 28.09.2012, p. 33905-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Human skin basement membrane-associated heparan sulphate proteoglycan: distinctive differences in ultrastructural localization as a function of developmental age. / Horiguchi, Y; Fine, J D; Couchman, J R.

    In: British Journal of Dermatology, Vol. 124, No. 5, 1991, p. 410-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Distribution, ultrastructural localization, and ontogeny of the core protein of a heparan sulfate proteoglycan in human skin and other basement membranes. / Horiguchi, Y; Couchman, J R; Ljubimov, A V; Yamasaki, H; Fine, J D.

    In: Journal of Histochemistry and Cytochemistry, Vol. 37, No. 7, 1989, p. 961-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Entactin: ultrastructural localization of an ubiquitous basement membrane glycoprotein in mouse skin. / Horiguchi, Y; Fine, J D; Ljubimov, A V; Yamasaki, H; Couchman, J R.

    In: Archives of Dermatological Research, Vol. 281, No. 6, 1989, p. 427-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Functions of proteoglycans at the cell surface. / Höök, M; Woods, A; Johansson, S; Kjellén, L; Couchman, J R.

    In: Novartis Foundation Symposium, Vol. 124, 1986, p. 143-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Proteoglycans in basement membranes. / Höök, M.; Couchman, J.; Woods, A.; Robinson, J.; Christner, J. E.

    In: Ciba Foundation symposium, Vol. 108, 01.12.1984, p. 44-59.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour. / Høye, Anette M; Couchman, John R; Wewer, Ulla M; Yoneda, Atsuko.

    In: Scientific Reports, Vol. 6, 28529, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The newcomer in the integrin family: Integrin α9 in biology and cancer. / Høye, Anette Melissa; Couchman, John Robert; Wewer, Ulla M.; Yoneda, Atsuko; Fukami, Kiyoko.

    In: Advances in Biological Regulation, Vol. 52, No. 2, 05.2012, p. 326-339.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Dynamics of extracellular matrix in ovarian follicles and corpora lutea of mice. / Irving-Rodgers, Helen F; Hummitzsch, Katja; Murdiyarso, Lydia S; Bonner, Wendy M; Sado, Yoshikazu; Ninomiya, Yoshifumi; Couchman, John R; Sorokin, Lydia M; Rodgers, Raymond J.

    In: Cell and Tissue Research, Vol. 339, No. 3, 2009, p. 613-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Rat embryo fibroblasts require both the cell-binding and the heparin-binding domains of fibronectin for survival. / Jeong, J; Han, I; Lim, Y; Kim, J; Park, I; Woods, A; Couchman, J R; Oh, E S.

    In: Biochemical Journal, Vol. 356, No. Pt 2, 2001, p. 531-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Essential contribution of tumor-derived perlecan to epidermal tumor growth and angiogenesis. / Jiang, Xinnong; Multhaupt, Hinke; Chan, En; Schaefer, Liliana; Schaefer, Roland M; Couchman, John R.

    In: Journal of Histochemistry and Cytochemistry, Vol. 52, No. 12, 2004, p. 1575-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Perlecan and tumor angiogenesis. / Jiang, Xinnong; Couchman, John R.

    In: Journal of Histochemistry and Cytochemistry, Vol. 51, No. 11, 2003, p. 1393-410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Steroid effects on cell morphology and cell proliferation. / King, R. J.B.; Couchman, J.; Yates, J.

    In: Biochemical Society Transactions, Vol. 9, No. 2, 01.01.1981.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Control of extracellular matrix assembly by syndecan-2 proteoglycan. / Klass, C M; Couchman, J R; Woods, A.

    In: Journal of Cell Science, Vol. 113 ( Pt 3), 2000, p. 493-506.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Attenuation of hedgehog acyltransferase-catalyzed sonic Hedgehog palmitoylation causes reduced signaling, proliferation and invasiveness of human carcinoma cells. / Konitsiotis, Antonios D; Chang, Shu-Chun; Jovanović, Biljana; Ciepla, Paulina; Masumoto, Naoko; Palmer, Christopher P; Tate, Edward W; Couchman, John Robert; Magee, Anthony I.

    In: PloS one, Vol. 9, No. 3, e89899, 2014, p. 1-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Structural basis of syndecan-4 phosphorylation as a molecular switch to regulate signaling. / Koo, Bon-Kyung; Jung, Young Sang; Shin, Joon; Han, Innoc; Mortier, Eva; Zimmermann, Pascale; Whiteford, James R; Couchman, John R; Oh, Eok-Soo; Lee, Weontae.

    In: Journal of Molecular Biology, Vol. 355, No. 4, 2005, p. 651-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Cellular roles of ADAM12 in health and disease. / Kveiborg, Marie; Albrechtsen, Reidar; Couchman, John R; Wewer, Ulla M.

    In: International Journal of Biochemistry & Cell Biology, Vol. 40, No. 9, 2008, p. 1685-702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Solution structure of a syndecan-4 cytoplasmic domain and its interaction with phosphatidylinositol 4,5-bisphosphate. / Lee, D; Oh, E S; Woods, A; Couchman, J R; Lee, W.

    In: Journal of Biological Chemistry, Vol. 273, No. 21, 1998, p. 13022-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Syndecan-1 and syndecan-4 are independent indicators in breast carcinoma. / Lendorf, Maria E; Manon-Jensen, Tina; Kronqvist, Pauliina; Multhaupt, Hinke A B; Couchman, John R.

    In: Journal of Histochemistry and Cytochemistry, Vol. 59, No. 6, 01.06.2011, p. 615-29.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases. / Lim, Hooi Ching; Couchman, John Robert.

    In: BBA General Subjects, Vol. 1840, No. 8, 18.01.2014, p. 2482–2490.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells. / Lim, Hooi Ching; Multhaupt, Hinke A. B.; Couchman, John R.

    In: Molecular Cancer, Vol. 14, No. 15, 27.01.2015, p. 1-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha. / Lim, Ssang-Taek; Longley, Robert L; Couchman, John R; Woods, Anne.

    In: Journal of Biological Chemistry, Vol. 278, No. 16, 2003, p. 13795-802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Ultrastructural immunocytochemical localization of chondroitin sulfate proteoglycan in Bruch's membrane of the rat. / Lin, W L; Essner, E; McCarthy, K J; Couchman, J R.

    In: Investigative Ophthalmology & Visual Science, Vol. 33, No. 6, 1992, p. 2072-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Increased proteoglycan synthesis by the cardiovascular system of coarctation hypertensive rats. / Lipke, D W; Couchman, J R.

    In: Journal of Cellular Physiology, Vol. 147, No. 3, 1991, p. 479-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Coarctation induces alterations in basement membranes in the cardiovascular system. / Lipke, D W; McCarthy, K J; Elton, T S; Arcot, S S; Oparil, S; Couchman, J R.

    In: Hypertension, Vol. 22, No. 5, 1993, p. 743-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Basement membrane abnormalities in human eyes with diabetic retinopathy. / Ljubimov, A V; Burgeson, R E; Butkowski, R J; Couchman, J R; Zardi, L; Ninomiya, Y; Sado, Y; Huang, Z S; Nesburn, A B; Kenney, M C.

    In: Journal of Histochemistry and Cytochemistry, Vol. 44, No. 12, 1996, p. 1469-79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Extracellular matrix alterations in human corneas with bullous keratopathy. / Ljubimov, A V; Burgeson, R E; Butkowski, R J; Couchman, J R; Wu, R R; Ninomiya, Y; Sado, Y; Maguen, E; Nesburn, A B; Kenney, M C.

    In: Investigative Ophthalmology & Visual Science, Vol. 37, No. 6, 1996, p. 997-1007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies. / Ljubimov, A V; Bartek, J; Couchman, J R; Kapuller, L L; Veselov, V V; Kovarik, J; Perevoshchikov, A G; Krutovskikh, V A.

    In: International Journal of Cancer, Vol. 50, No. 4, 1992, p. 562-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Retinal basement membrane alterations in human diabetic retinopathy eyes. / Ljubimov, A. V.; Burgeson, R. E.; Butkowski, R. J.; Couchman, J. R.; Huang, Z.; Nesburn, A. B.; Kenney, M. C.

    In: Investigative Ophthalmology and Visual Science, Vol. 37, No. 3, 15.02.1996.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Control of morphology, cytoskeleton and migration by syndecan-4. / Longley, R L; Woods, A; Fleetwood, A; Cowling, G J; Gallagher, J T; Couchman, J R.

    In: Journal of Cell Science, Vol. 112 ( Pt 20), 1999, p. 3421-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage. / Lydolph, Magnus C; Morgan-Fisher, Marie; Høye, Anette M; Couchman, John R; Wewer, Ulla M; Yoneda, Atsuko.

    In: Experimental Cell Research, Vol. 315, No. 19, 2009, p. 3312-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Co-deposition of basement membrane components during the induction of murine splenic AA amyloid. / Lyon, A W; Narindrasorasak, S; Young, I D; Anastassiades, T; Couchman, J R; McCarthy, K J; Kisilevsky, R.

    In: Laboratory Investigation, Vol. 64, No. 6, 1991, p. 785-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Cellular responses to the HEPII domain of fibronectin require N-sulphation of cell-surface heparan sulphate proteoglycan. / Mahalingam, Y.; Gallagher, J.T.; Couchman, John Robert.

    In: International Journal of Experimental Pathology, Vol. 89, No. 3, 2008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Cellular adhesion responses to the heparin-binding (HepII) domain of fibronectin require heparan sulfate with specific properties. / Mahalingam, Yashithra; Gallagher, John T; Couchman, John R.

    In: Journal of Biological Chemistry, Vol. 282, No. 5, 2006, p. 3221-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Mapping of matrix metalloproteinase cleavage sites on syndecan-1 and syndecan-4 ectodomains. / Manon-Jensen, Tina; Multhaupt, Hinke A B; Couchman, John R.

    In: F E B S Journal, Vol. 280, No. 10, 05.2013, p. 2320-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Proteoglycans in health and disease: the multiple roles of syndecan shedding. / Manon-Jensen, Tina; Itoh, Yoshifumi; Couchman, John R.

    In: FEBS Journal, Vol. 277, No. 19, 2010, p. 3876-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Basement membrane proteoglycans in glomerular morphogenesis: chondroitin sulfate proteoglycan is temporally and spatially restricted during development. / McCarthy, K J; Bynum, K; St John, P L; Abrahamson, D R; Couchman, J R.

    In: Journal of Histochemistry and Cytochemistry, Vol. 41, No. 3, 1993, p. 401-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Basement membrane chondroitin sulfate proteoglycans: localization in adult rat tissues. / McCarthy, K J; Couchman, J R.

    In: Journal of Histochemistry and Cytochemistry, Vol. 38, No. 10, 1990, p. 1479-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Ultrastructural localization of the core protein of a basement membrane-specific chondroitin sulfate proteoglycan in adult rat skin. / McCarthy, K J; Horiguchi, Y; Couchman, J R; Fine, J D.

    In: Archives of Dermatological Research, Vol. 282, No. 6, 1990, p. 397-401.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Immunological characterization of a basement membrane-specific chondroitin sulfate proteoglycan. / McCarthy, K J; Accavitti, M A; Couchman, J R.

    In: Journal of Cell Biology, Vol. 109, No. 6 Pt 1, 1989, p. 3187-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Basement membrane-specific chondroitin sulfate proteoglycan is abnormally associated with the glomerular capillary basement membrane of diabetic rats. / McCarthy, K J; Abrahamson, D R; Bynum, K R; St John, P L; Couchman, J R.

    In: Journal of Histochemistry and Cytochemistry, Vol. 42, No. 4, 1994, p. 473-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Proteoglycans, ion channels and cell-matrix adhesion. / Mitsou, Ioli; Multhaupt, Hinke A.B.; Couchman, John R.

    In: Biochemical Journal, Vol. 474, No. 12, 15.06.2017, p. 1965-1979.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Phosphorylation and mRNA splicing of collapsin response mediator protein-2 determine inhibition of rho-associated protein kinase (ROCK) II function in carcinoma cell migration and invasion. / Morgan-Fisher, Marie; Couchman, John R; Yoneda, Atsuko.

    In: The Journal of Biological Chemistry, Vol. 288, No. 43, 25.10.2013, p. 31229-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Syndecan signaling: when, where and why? / Multhaupt, H A B; Yoneda, A; Whiteford, J R; Oh, E-S; Lee, W; Couchman, J R.

    In: Journal of Physiology and Pharmacology, Vol. 60 Suppl 4, 2009, p. 31-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Heparan sulfate biosynthesis : methods for investigation of the heparanosome. / Multhaupt, Hinke A B; Couchman, John R.

    In: Journal of Histochemistry and Cytochemistry, Vol. 60, No. 12, 12.2012, p. 908-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Extracellular matrix component signaling in cancer. / Multhaupt, Hinke A. B.; Leitinger, Birgit; Gullberg, Donald; Couchman, John R.

    In: Advanced Drug Delivery Reviews, Vol. 97, 01.02.2016, p. 28–40.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice. / Nam, Eon Jeong; Hayashida, Kazutaka; Aquino, Rafael S.; Couchman, John R.; Kozar, Rosemary A.; Liu, Jian; Park, Pyong Woo.

    In: Hepatology, Vol. 66, No. 5, 01.11.2017, p. 1601-1615.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Syndecan-4 proteoglycan regulates the distribution and activity of protein kinase C. / Oh, E S; Woods, A; Couchman, J R.

    In: Journal of Biological Chemistry, Vol. 272, No. 13, 1997, p. 8133-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Syndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4,5-bisphosphate coordinately regulate protein kinase C activity. / Oh, E S; Woods, A; Lim, S T; Theibert, A W; Couchman, J R.

    In: Journal of Biological Chemistry, Vol. 273, No. 17, 1998, p. 10624-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 916617