Jens Lykkesfeldt

Professor

Preclinical Disease Biology
Ridebanevej 9, 1870 Frederiksberg C
- jopl@sund.ku.dk
- http://www.isb.life.ku.dk/Service/Telefonbog/Personvisning.aspx?personid=1079
- https://ivs.ku.dk/ansatte/?pure=da%2Fpersons%2Fjens-lykkesfeldt(6e71ebed-c114-42ab-9ae9-6333f14bf8ad).html
Phone: +4535333163

Member of:

Lifepharm

ORCID: 0000-0002-6514-8407

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2024
E-pub ahead of print
Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease
Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.
Research output: Contribution to journal › Journal article › Research › peer-review
2023
Published
Effect of Remote Ischaemic Preconditioning on Perioperative Endothelial Dysfunction in Non-Cardiac Surgery: A Randomised Clinical Trial
Wahlstrøm, K. L., Hansen, H. F., Kvist, M., Burcharth, Jakob, Lykkesfeldt, Jens, Gögenur, Ismail & Ekeloef, S., 16 Mar 2023, In: Cells. 12, 6, 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dietary Long-Chain Fatty Acids Accelerate Metabolic Dysfunction in Guinea Pigs with Non-Alcoholic Steatohepatitis
Pedersen, Kamilla, Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2023, In: Nutrients. 15, 2445.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Does Aging Affect Vitamin C Status Relative to Intake? Findings from NHANES 2017-2018
Carr, A. C. & Lykkesfeldt, Jens, 2023, In: Nutrients. 15, 4, 10 p., 892.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials
Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Factors Affecting the Vitamin C Dose-Concentration Relationship: Implications for Global Vitamin C Dietary Recommendations
Carr, A. C. & Lykkesfeldt, Jens, 2023, In: Nutrients. 15, 7, 19 p., 1657.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The dietary regulation of LEAP2 depends on meal composition in mice
Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, Jesse A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023
Lykkesfeldt, Jens & Carr, A. C., 2023, In: Food and Nutrition Research. 67, 19 p., 10300.
Research output: Contribution to journal › Review › Research › peer-review
2022
Published
A long‐term energy‐rich diet increases prefrontal bdnf in sprague‐dawley rats
Virtuoso, Alessandro, Tveden-Nyborg, Pernille, Schou‐pedersen, A. M. V., Lykkesfeldt, Jens, Müller, H. K., Elfving, B. & Sørensen, Dorte Bratbo, 2022, In: Nutrients. 14, 1, 126.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
Pedersen, Kamilla, Kruhøffer, L. L., Lykkesfeldt, Jens & Kousholt, B. S., 2022, In: Acta Veterinaria Scandinavica. 64, 38.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs
Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Estimation of Vitamin C Intake Requirements Based on Body Weight: Implications for Obesity
Carr, A. C., Block, G. & Lykkesfeldt, Jens, 2022, In: Nutrients. 14, 7, 8 p., 1460.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Lower Vitamin C Levels Are Associated With Less Improvement in Negative Symptoms in Initially Antipsychotic-Naïve Patients With First-Episode Psychosis
Myken, A. N., Ebdrup, Bjørn, Sørensen, M. E., Broberg, B. V., Skjerbæk, M. W., Glenthøj, Birte Yding, Lykkesfeldt, Jens & Nielsen, Mette Ødegaard, 2022, In: The international journal of neuropsychopharmacology. 25, 8, p. 613-618 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
NPFF Decreases Activity of Human Arcuate NPY Neurons: A Study in Embryonic-Stem-Cell-Derived Model
Pedersen, Lola Julie Torz, Niss, K., Lundh, S., Rekling, Jens Christian, Quintana, C. D., Frazier, S. E. D., Mercer, A. J., Cornea, A., Bertelsen, C. V., Gerstenberg, M. K., Hansen, A. M. K., Guldbrandt, M., Lykkesfeldt, Jens, John, L. M., Villaescusa, J. C. & Petersen, N., 2022, In: International Journal of Molecular Sciences. 23, 6, 15 p., 3260.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Prolonged insulin-induced hypoglycaemia reduces ß-cell activity rather than number in pancreatic islets in non-diabetic rats
Jensen, Vivi Flou Hjorth, Mølck, A. M., Nowak, J., Fels, J. J., Lykkesfeldt, Jens & Bøgh, I. B., 2022, In: Scientific Reports. 12, 14113.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation
Jensen, Ditte Marie, Skovsted, Gry Freja, Bonde, M. F. B., Bentzon, J. F., Rolin, B., Franck, G., Ougaard, M. K. E., Voetmann, Louise Marie, Bachmann, J. C., Uryga, A., Pyke, C., Kirk, R. K., Hvid, H., Knudsen, L. B., Lykkesfeldt, Jens & Nyberg, M., 2022, In: Atherosclerosis Plus. 49, p. 32-41 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet
Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig
Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.
Research output: Contribution to journal › Journal article › Research › peer-review
2021
Published
Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE^−/− mice
Christophersen, D. V., Møller, Peter, Thomsen, Morten Bækgaard, Lykkesfeldt, Jens, Loft, Steffen, Wallin, H., Vogel, U. & Jacobsen, N. R., 2021, In: FASEB Journal. 35, 3, 14 p., e21307.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
BCPT policy for experimental and clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 4-8
Research output: Contribution to journal › Review › Research › peer-review
Published
Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels
Brunse, Anders, Peng, Y., Li, Y., Lykkesfeldt, Jens & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 636638.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Collagen remodelling and plasma ascorbic acid levels in patients suspected of inherited bleeding disorders harbouring germline variants in collagen‐related genes
Fager Ferrari, M., Zetterberg, E., Rossing, Caroline Maria, Manon‐jensen, T., Pehrsson, M., Karsdal, M. A., Lykkesfeldt, Jens & Leinoe, E., 2021, In: Haemophilia. 27, 1, p. e69-e77
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Decreased expression of the GLP-1 receptor after segmental artery injury in mice
Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease
Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis
Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Discrepancies in global vitamin C recommendations: a review of RDA criteria and underlying health perspectives
Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Critical Reviews in Food Science and Nutrition. 61, 5, p. 742-755 14 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Food intake rather than blood glucose levels affects the pharmacokinetic profile of insulin aspart in pigs
Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Porsgaard, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 6, p. 783-794
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD
Jensen, Victoria Svop, Fledelius, C., Zachodnik, C., Damgaard, J., Nygaard, H., Tornqvist, K. S., Kirk, R. K., Viuff, B. M., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Journal of Translational Medicine. 19, 1, 80.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation
Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model
Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 9, 18 p., 1198.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease
Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Temporal development of dyslipidemia and nonalcoholic fatty liver disease (Nafld) in syrian hamsters fed a high‐fat, high‐fructose, high‐cholesterol diet
Jensen, Victoria Svop, Fledelius, C., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Nutrients. 13, 2, p. 1-18 18 p., 604.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs
Ipsen, David Højland, Agerskov, R. H., Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Scientific Reports. 11, 2955.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis
Ipsen, David Højland, Skat-Rørdam, Josephine, Svenningsen, M., Andersen, Mia Trein, Latta, M., Buelund, Lene Elisabeth, Lintrup, K., Skaarup, R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 4, p. 583-593
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The role of vitamin C in epigenetic cancer therapy
Mikkelsen, Stine Ulrik, Gillberg, Linn, Lykkesfeldt, Jens & Grønbæk, Kirsten, 2021, In: Free Radical Biology and Medicine. 170, p. 179-193 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C: From Bench to Bedside
Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Nutrients. 13, 4, 3 p., 1102.
Research output: Contribution to journal › Editorial › Research › peer-review
2020
Published
The counterregulatory response to hypoglycaemia in the pig
Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Ludvigsen, T. P., Porsgaard, T., Schou-Pedersen, A. M. V., Fels, J. J., Lykkesfeldt, Jens & Refsgaard, H. H. F., Oct 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 4, p. 278-286
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A systematic Cochrane Review of antioxidant supplementation lung disease for cystic fibrosis
Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2020, In: Paediatric Respiratory Reviews. 33, p. 28-29
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
Animal Models of Fibrosis in Nonalcoholic Steatohepatitis: Do They Reflect Human Disease?
Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Advances in Nutrition. 11, 6, p. 1696–1711
Research output: Contribution to journal › Review › Research › peer-review
Published
Ascorbate maintains a low plasma oxygen level
Injarabian, L., Scherlinger, M., Devin, A., Ransac, S., Lykkesfeldt, Jens & Marteyn, B. S., 2020, In: Scientific Reports. 10, 1, 6 p., 10659.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation
Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 9.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Endothelial dysfunction and myocardial injury after major emergency abdominal surgery: a prospective cohort study
Ekeloef, S., Oreskov, J. O., Falkenberg, A., Burcharth, J., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, Ismail, 2020, In: BMC Anesthesiology. 20, 9 p., 67.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Formation and Glomerular Deposition of Immune Complexes in Mice Administered Human Antibodies: Evaluation of Dose, Frequency, and Biomarkers
Boysen, L., Viuff, B. M., Landsy, L. H., Lykkesfeldt, Jens, Raymond, J. T., Price, S. A., Pelzer, H. & Lauritzen, B., 2020, In: Toxicologic Pathology. 48, 4, p. 570-585 16 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Hypophosphatemic Hypovitaminosis D Induces Osteomalacia in the Adult Female Rat
Durup, D., Diaz-delCastillo, M., Morgenlykke, J., Jensen, Lars Thorbjørn, Frandsen, E., Abelson, Klas, Pedersen, L., Lykkesfeldt, Jens, Ding, M., Jørgensen, Niklas Rye, Syberg, S., Petersen, S. & Heegaard, Anne-Marie, 2020, In: Endocrinology. 161, 8, bqaa100.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Importance of gestational hypoglycaemia for foetal malformations and skeletal development in rats
Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens, Fels, J. J., Andersen, L., Renaut, R., McGuigan, F., Åkesson, K. E. & Bøgh, I. B., 2020, In: Reproductive Toxicology. 91, p. 14-26 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats
Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B., Nowak, J., Viuff, B. M., Rasmussen, C. L. M., Voetmann, Louise Marie, Fels, J. J., Madsen, S. H., McGuigan, F. E., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Akesson, K. E., 2020, In: Scientific Reports. 10, 1, 13 p., 5609.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes
Andreasen, L. J., Kirk, R. K., Fledelius, C., Yorek, M. A., Lykkesfeldt, Jens & Akerstrom, T., 2020, In: Journal of Diabetes Research. 2020, 13 p., 9626398.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Malnutrition predisposes to endotoxin-induced edema and impaired inflammatory response in parenterally fed piglets
Bæk, Ole, Fabiansen, C., Friis, Henrik, Ritz, C., Koch, Jørgen, Willesen, Jakob, Heegaard, P. M. H., Lykkesfeldt, Jens, Briend, A., Golden, M. H., Sangild, Per Torp & Thymann, Thomas, 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 4, p. 668-676
Research output: Contribution to journal › Journal article › Research › peer-review
Published
On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence
Lykkesfeldt, Jens, 2020, In: Redox Biology. 34, 13 p., 101532.
Research output: Contribution to journal › Review › Research › peer-review
Published
Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease
Christiansen, L. B., Morsing, Malene Kjelin, Reimann, Maria Josefine, Martinussen, Torben, Birlie, Z., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2020, In: Antioxidants. 9, 9 p., 827.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice
Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Brockhoff, P. M. B., Seested, T. & Refsgaard, H. H. F., 2020, In: Experimental and Clinical Endocrinology and Diabetes. 128, 5, p. 332-338 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models
Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.
Research output: Contribution to journal › Journal article › Research › peer-review
2019
Published
Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes
Gillberg, Linn, mxz703, mxz703, Nasif, A., Ohtani, H., Madaj, Z., Hansen, Jakob Werner, Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, Jens, Hajkova, P., Jones, P. A. & Grønbæk, Kirsten, 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease
Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537
Research output: Contribution to journal › Review › Research › peer-review
Published
Peri-operative endothelial dysfunction in patients undergoing minor abdominal surgery: An observational study
Busch, S. V. E., Godthaab, C., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., Feb 2019, In: European Journal of Anaesthesiology. 36, 2, p. 130-134 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
An ELISA for detection of complement-bound circulating immune complexes in mice
Boysen, L., Lauritzen, B., Viuff, B. M., Lykkesfeldt, Jens & Landsy, L. H., 2019, In: Journal of Immunotoxicology. 16, 1, p. 82-86 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Antioxidant supplementation for lung disease in cystic fibrosis
Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2019, In: Cochrane Database of Systematic Reviews. 2019, 10, CD007020.
Research output: Contribution to journal › Review › Research › peer-review
Published
Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model
Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Brockhoff, P. M. B., Seested, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2019, In: Obesity Science & Practice. 5, 3, p. 281-288
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Determination of reduced and oxidized coenzyme Q₁₀ in canine plasma and heart tissue by HPLC-ECD: Comparison with LC-MS/MS quantification
Schou-Pedersen, A. M. V., Schemeth, D. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 8, 253.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Expression of endothelin type B receptors in uterine artery smooth muscle cells from pregnant Guinea pigs
Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2019, In: Placenta. 77, p. 8-15 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Formation and glomerular deposition of immune complexes in mice administered bovine serum albumin: Evaluation of dose, frequency, and biomarkers
Boysen, L., Viuff, B. M., Landsy, L. H., Price, S. A., Raymond, J. T., Lykkesfeldt, Jens & Lauritzen, B., 2019, In: Journal of Immunotoxicology. 16, 1, p. 191-200 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Generic immune complex assay for detection of murine anti-drug-antibodies in complex with human IgG
Boysen, L., Sprinkel, A. M. E., Lauritzen, B., Breinholt, J., Lykkesfeldt, Jens, Viuff, B. M. & Landsy, L. H., 2019, In: Biologicals. 60, p. 42-48 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Glycemic control during pregnancy — A predictor of vitamin C status at labor in type 1 diabeticwomen?
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 6, 153.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model
Ipsen, David Højland, Skat-Rørdam, Josephine, Tsamouri, M. M., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Molecular Genetics and Genomics. 294, 3, p. 649–661
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Når leveren bliver for fed
Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Aktuel Naturvidenskab. 2019, 3, p. 28-31
Research output: Contribution to journal › Journal article › Communication
Published
Telomere length and genotoxicity in the lung of rats following intragastric exposure to food-grade titanium dioxide and vegetable carbon particles
Jensen, Ditte Marie, Løhr, M., Sheykhzade, Majid, Lykkesfeldt, Jens, Wils, Regitze Sølling, Loft, Steffen & Møller, Peter, 2019, In: Mutagenesis. 34, 2, p. 203-214 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The Pharmacokinetics of Vitamin C
Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.
Research output: Contribution to journal › Review › Research › peer-review
Published
The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial
Zahid, J. A., Isbrand, A., Kleif, J., Schou-Pedersen, A. V., Lykkesfeldt, Jens, Madsen, M. T. & Gögenur, Ismail, 2019, In: Journal of Pineal Research. 67, 3, e12600.
Research output: Contribution to journal › Letter › Research › peer-review
Published
Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method
Ørstrup, Laura Kofoed Hvidsten, Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, Jens & Glud, A. N., 2019, In: Heliyon. 5, 11, 8 p., e02892.
Research output: Contribution to journal › Journal article › Research › peer-review
2018
Published
Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat
Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens & Bøgh, I. B., Apr 2018, In: Reproductive Toxicology. 77, p. 1-24 24 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by ternary complex factors and the actin cytoskeleton
Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Rippe, C., Dreier, R., Berg, J. O., Lykkesfeldt, Jens, Hedin, U. & Sward, K., Apr 2018.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published
Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles
Jensen, Ditte Marie, Christophersen, D. V., Sheykhzade, Majid, Skovsted, Gry Freja, Lykkesfeldt, Jens, Münter, R., Roursgaard, Martin, Loft, Steffen & Møller, Peter, 26 Feb 2018, In: Particle and Fibre Toxicology. 15, p. 1-18 12.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD
Schou-Pedersen, A. M. V. & Lykkesfeldt, Jens, 1 Feb 2018, In: Journal of Analytical Methods in Chemistry. 2018, 7 p., 6148515.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats
Jensen, Vivi Flou Hjorth, Molck, A. M., Soeborg, H., Nowak, J., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jan 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 1, p. 165-175
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner
Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, Jens, Glerup, S. & Nielsen, M. S., 2018, In: Behavioural Brain Research. 348, p. 90-100 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats
Jensen, Victoria Svop, Hvid, H., Damgaard, J., Nygaard, H., Ingvorsen, C., Wulff, E. M., Lykkesfeldt, Jens & Fledelius, C., 2018, In: Diabetology and Metabolic Syndrome. 10, 13 p., 4.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Early life vitamin C deficiency does not alter morphology of hippocampal CA1 pyramidal neurons or markers of synaptic plasticity in a Guinea pig model
Hansen, S. N., Jørgensen, J. M. B., Nyengaard, J. R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Nutrients. 10, 6, 749.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Seested, T., Gram-Nielsen, S., Kristensen, N. R. & Refsgaard, H., 2018, In: Journal of Diabetes Research. 2018, 17 p., 1205121.
Research output: Contribution to journal › Review › Research › peer-review
Published
Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity
Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High-fat feeding induces mobilization of vitamin C in obese prone rats
Tranberg, B., Hellgren, L. I., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 119, p. 167-169 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Holder C-vitamin dine blodkar sunde?
Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2018
Research output: Other contribution › Net publication - Internet publication › Communication
Published
Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis
Ipsen, David Højland, Rolin, B., Rakipovski, G., Skovsted, Gry Freja, Madsen, A., Kolstrup, S., Schou-Pedersen, A. M., Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 704-713
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Long term Westernized diet leads to region-specific changes in brain signaling mechanisms
Hansen, S. N., Ipsen, David Højland, Schou-Pedersen, A. M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Neuroscience Letters. 676, p. 85-91 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics
Rune, Ida, Rolin, B., Lykkesfeldt, Jens, Nielsen, Dennis Sandris, Krych, Lukasz, Kanter, J. E., Bornfeldt, K. E., Kihl, Pernille, Buschard, K., Josefsen, K., Fels, J. J., Mortensen, A., Christoffersen, B., Kirk, R. K. & Hansen, Axel Kornerup, 2018, In: Scientific Reports. 8, 1, 12 p., 5416.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Cellular and Molecular Life Sciences. 75, 18, p. 3313-3327 15 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Pharmacological modulation of colorectal distension evoked potentials in conscious rats
Nissen, T. D., Brock, C., Lykkesfeldt, Jens, Lindström, E. & Hultin, L., 2018, In: Neuropharmacology. 140, p. 193-200 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation
Hansen, S. N., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Antioxidants. 7, 7, p. 11 82.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide
Jensen, Ditte Marie, Skovsted, Gry Freja, Lykkesfeldt, Jens, Dreier, R., Berg, J. O., Jeppesen, J. L., Sheykhzade, Majid, Loft, Steffen & Møller, Peter, 2018, In: Food and Chemical Toxicology. 120, p. 321-327 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2017
Published
Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials
Larsen, E. L., Cejvanovic, V., Kjær, L. K., Pedersen, M. T., Popik, S. D., Hansen, L. K., Andersen, Jon Thor Trærup, Solem, Espen Victor Jimenez, Broedbaek, K., Petersen, M., Weimann, A., Henriksen, T., Lykkesfeldt, Jens, Torp-Pedersen, C. & Poulsen, Henrik Enghusen, Aug 2017, In: British Journal of Clinical Pharmacology. 83, 8, p. 1643-1653
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats
Jensen, Vivi Flou Hjorth, Molck, A., Berthelsen, L. O., Alifrangis, L., Andersen, L., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 1, p. 53-66
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs
Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, Stine Brandt & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Endothelial dysfunction in the early postoperative period after major colon cancer surgery.
Ekeløf, S., Larsen, M. H., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, Feb 2017, In: British Journal of Anaesthesia. 118, 2, p. 200-206
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice
Petersen, Karen Ekkelund, Lykkesfeldt, Jens, Raun, K. & Rakipovski, G., Jan 2017, In: Experimental Biology and Medicine (Maywood). 242, 1, p. 88-91
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing
Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain
Jensen, Vivi Flou Hjorth, Molck, A., Chapman, M., Alifrangis, L., Andersen, L., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: International Journal of Endocrinology. 2017, 14 p., 7861236.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of High Inspiratory Oxygen Fraction on Endothelial Dysfunction in Healthy Volunteers: A Randomized Controlled Cross-over Pilot Study
Larsen, M. H. H., Ekeløf, S., Kokotovic, D., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., 2017, In: Anesthesia and Analgesia. 125, 5, p. 1793–1796
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration
Reimann, Maria Josefine, Haggstrom, J., Moller, J. E., Lykkesfeldt, Jens, Falk, T. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 2, p. 295-302 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Poor vitamin C status late in pregnancy is associated with increased risk of complications in type 1 diabetic women: A cross-sectional study
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 3, 9 p., 186.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C deficiency reduces muscarinic receptor coronary artery vasoconstriction and plasma tetrahydrobiopterin concentration in guinea pigs
Skovsted, Gry Freja, Tveden-Nyborg, Pernille, Lindblad, M. M., Hansen, S. N. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 7, 14 p., 691.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: A single-arm phase II trial
Nielsen, Torben Kjær, Højgaard, M., Andersen, Jon Thor Trærup, Jørgensen, N. R., Zerahn, B., Kristensen, B., Henriksen, T., Lykkesfeldt, Jens, Mikines, K. J. & Poulsen, Henrik Enghusen, 2017, In: Translational Andrology and Urology. 6, 3, p. 517-528 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2016
Published
Dyslipidemia: Obese or Not Obese-That Is Not the Question
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Dec 2016, In: Current Obesity Reports. 5, 4, p. 405-412
Research output: Contribution to journal › Review › Research › peer-review
Published
Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance
Jothery, A. H. A., Vaanholt, L. M., Mody, N., Arnous, A., Lykkesfeldt, Jens, Bunger, L., Hill, W. G., Mitchell, S. E., Allison, D. B. & Speakman, J. R., 14 Nov 2016, In: Scientific Reports. 6, 12 p., 36353 .
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines
Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Is Diabetes Associated with Lower Vitamin C Status in Pregnant Women? A Prospective Study
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, Oct 2016, In: International Journal for Vitamin and Nutrition Research. 86, 5-6, p. 184-189
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice
Christophersen, D. V., Raun Jacobsen, N., Guerra Andersen, M. H., Connell, S. P., Barfod, K. K., Thomsen, Morten Bækgaard, Miller, M. R., Duffin, R., Lykkesfeldt, Jens, Vogel, U. B., Wallin, E. H. R., Loft, Steffen, Roursgaard, Martin & Møller, Peter, 14 Sep 2016, In: Toxicology. 371, p. 29-40 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research
Jensen, Victoria Svop, Porsgaard, T., Lykkesfeldt, Jens & Hvid, H., 15 Aug 2016, In: American Journal of Translational Research. 8, 8, p. 3574-3584
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain
Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey
Lykkesfeldt, Jens, Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 2, p. 161-164
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Maternal vitamin C deficiency does not reduce hippocampal volume and beta-tubulin III intensity in prenatal Guinea pigs
Hansen, S. N., Schjoldager, J. G., Paidi, M. D., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Jul 2016, In: Nutrition Research. 36, 7, p. 696-702
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The kidneys play a central role in the clearance of rhGH in rats
Vestergaard, Bill, Thygesen, P., Kreilgaard, M., Fels, J. J., Lykkesfeldt, Jens & Agerso, H., 30 Apr 2016, In: European Journal of Pharmaceutical Sciences. 86, p. 29-33
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Normal Weight Dyslipidemia: Is It All About the Liver?
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Mar 2016, In: Obesity. 24, 3, p. 556-567 12 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet
Rakipovski, G., Lykkesfeldt, Jens & Raun, K., 20 Jan 2016, In: P L o S One. 11, 1, e0147412.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Histopathological nerve and skeletal muscle changes in rats subjected to persistent insulin-induced hypoglycemia
Jensen, Vivi Flou Hjorth, Mølck, A., Heydenreich, A., Jensen, K. J., Bertelsen, L. O., Alifrangis, L., Andersen, L., Søeborg, H., Chapman, M., Lykkesfeldt, Jens & Bøgh, I. B., Jan 2016, In: Toxicologic Pathology. 29, 1, p. 17-30 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
_L-dehydroascorbic acid can substitute _L-ascorbic acid as dietary vitamin C source in guinea pigs
Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies
Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs
Ipsen, David Højland, Tveden-Nyborg, Pernille, Rolin, B., Rakipovski, G., Beck, M., Mortensen, L. W., Færk, L., Heegaard, P. M. H., Møller, Peter & Lykkesfeldt, Jens, 2016, In: Nutrition & Metabolism. 13, p. 51
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice
Rune, Ida, Rolin, B., Larsen, C. S., Nielsen, Dennis Sandris, Kanter, J. E., Bornfeldt, K. E., Lykkesfeldt, Jens, Buschard, K., Kirk, R. K., Christoffersen, B., Fels, J. J., Josefsen, K., Kihl, Pernille & Hansen, Axel Kornerup, 2016, In: P L o S One. 11, 1, 16 p., e0146439.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial
Rasmussen, S. T., Andersen, Jon Thor Trærup, Nielsen, T. K., Cejvanovic, V., Petersen, K. M., Henriksen, T., Weimann, A., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2016, In: Redox Biology. 9, p. 32-38
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitaminer til hjernen
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Aktuel Naturvidenskab. 2016, 4, p. 8-11 4 p.
Research output: Contribution to journal › Journal article › Research
2015
Published
Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design
Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chronic dyslipidemia induces fatty liver disease in Guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Lower limb ischaemia and reperfusion injury in healthy volunteers measured by oxidative and inflammatory biomarkers
Halladin, N. L., Busch, S. V. E., Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 10 Apr 2015, In: Perfusion. 30, 1, p. 64-70 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study
Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In vivo toxicity of cationic micelles and liposomes
Knudsen, K. B., Northeved, H., Kumar Ek, P., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, Jens, Jantzen, K., Loft, Steffen, Møller, Peter & Roursgaard, Martin, 25 Feb 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study
Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults
Hemmingsen, J. G., Rissler, J., Lykkesfeldt, Jens, Sallsten, G., Kristiansen, J., Møller, Peter & Loft, Steffen, 2015, In: Particle and Fibre Toxicology. 12, 10 p., 6.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs
Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation
Nielsen, Torben Kjær, Højgaard, M., Andersen, J. T. T., Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Mikines, K. J., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 343-348 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals
Ludvigsen, Trine Pagh, Kirk, R. K., Christoffersen, B. Ø., Pedersen, H. D., Martinussen, Torben, Kildegaard, J., Heegaard, P. M. H., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2015, In: Journal of Translational Medicine. 13, 12 p., 312.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum
Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2014
Published
Positive charge, negative effect: the impact of cationic nanoparticles in the brain
Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.
Research output: Contribution to journal › Editorial › Research › peer-review
Published
Antioxidant supplementation for lung disease in cystic fibrosis
Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors
Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression
Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Differential toxicological response to positively and negatively charged nanoparticles in the rat brain
Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Does vitamin C deficiency affect cognitive development and function?
Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Does vitamin C deficiency promote fatty liver disease development?
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.
Research output: Contribution to journal › Review › Research › peer-review
Published
Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies
Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes
Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study
Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs
Boonen, H. C. M., Moesgaard, S. G., Birck, M. M., Christoffersen, B. Ø., Cirera, Susanna, Heegaard, P. M. H., Højbøge, T. R., Jensen, Lars Jørn, Mortensen, A., Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, J. & Lykkesfeldt, Jens, 2014, In: Pflügers ARchiv (European Journal of Physiology). 466, 12, p. 2167-2176 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice
Christensen, B. T., Hansen, Axel Kornerup & Lykkesfeldt, Jens, 2014, In: European Journal of Nutrition. 53, 6, p. 1441-1444 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain
Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction
Halladin, N. L., Busch, S. V. E., Jensen, S. E., Aarøe, J., Kjærgaard, B., Heegaard, P. M. H., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, p. 483-488 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model
Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: Journal of Critical Care. 29, 1, p. 184.e9-184.e13 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Non-terminal blood sampling techniques in Guinea pigs
Birck, M. M., Tveden-Nyborg, Pernille, Lindblad, M. M. & Lykkesfeldt, Jens, 2014, In: Journal of Visualized Experiments. 92, e51982.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains
Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial
Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, I., 2014, In: PloS one. 9, 1, 7 p., e87413.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The kidneys play an important role in the clearance of rFVIIa in rats
Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C
Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2013
Published
Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent
Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin
Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo
Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
Jørgensen, A., Brødbæk, K., Fink-Jensen, Anders, Knorr, U., Greisen Søndergaard, M., Henriksen, T., Weimann, A., Jepsen, P., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2013, In: Psychiatry Research. 209, 3, p. 417–423 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function
Mortensen, A. & Lykkesfeldt, Jens, 2013, In: Biomarkers. 18, 1, p. 55-62 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokinetics
Vestergaard, Bill, Agersø, H. & Lykkesfeldt, Jens, 2013, In: Basic & Clinical Pharmacology & Toxicology Online. 113, 2, p. 75-86 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model
Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, Jens & Lauritzen, B., 2013, In: Haemophilia Online. 19, 6, p. 913-919 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs
Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Regulation of vitamin C homeostasis during deficiency
Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Translational aspects of rectal evoked potentials: a comparative study in rats and humans
Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Whey protein reduces early life weight gain in mice fed a high-fat diet
Christensen, B. T., Hellgren, L., Lykkesfeldt, Jens, Sejrsen, K., Jeamet, A., Rune, Ida, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2013, In: PLOS ONE. 8, 8, 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2012
Published
A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)
Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used
Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats
Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs
Tveden-Nyborg, Pernille, Andersen, S. H., Miyashita, N., Moos, T., Poulsen, Henrik Enghusen & Lykkesfeldt, Jens, 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 110, 6, p. 524-529 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs
Tveden-Nyborg, Pernille, Vogt, L., Schjoldager, J. G., Jeannet, N., Andersen, S. H., Paidi, M. D., Christen, S. & Lykkesfeldt, Jens, 2012, In: P L o S One. 7, 10, 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial
Madsen, M. T., Kücükakin, B., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2012, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 22, 3, p. 215-219 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs
Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Role of vitamin C and E supplementation on IL-6 in response to training
Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C and its role in brain development and cognition
Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2012, Nutrition and mental performance: a develomental perspective. Riby, L., Smith, M. & Foster, J. (eds.). Palgrave Macmillan, p. 29-52 24 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
What is the optimum intake of vitamin C in humans?
Frei, B., Birlouez-Aragon, I. & Lykkesfeldt, Jens, 2012, In: Critical Reviews in Food Science and Nutrition. 52, 9, p. 815-829 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2011
Published
The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice
Rune, Ida, Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Ellekilde, M., Lykkesfeldt, Jens, Hansen, Camilla Hartmann Friis & Rolin, B., Nov 2011. 1 p.
Research output: Contribution to conference › Poster › Research
Published
Animal models in pharmacology and toxicology
Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training
Yfanti, C., Nielsen, A. R., Åkerström, T., Nielsen, S., Rose, A. J., Richter, Erik A., Lykkesfeldt, Jens, Fischer, C. P. & Pedersen, Bente Klarlund, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 5, p. E761-E770 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells
Frikke-Schmidt, H. R., Roursgaard, Martin, Lykkesfeldt, Jens, Loft, Steffen, Nøjgaard, J. K. & Møller, Peter, 2011, In: Toxicology Letters. 203, 3, p. 181-189 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Fluctuating hyperglycaemia increases oxidative stress response in lean rats compared to sustained hyperglycaemia despite lower glycaemic exposure
Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2011, In: Diabetes and Vascular Disease Research. 8, 4, p. 295-298 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs
Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille, Birck, M. M. & Lykkesfeldt, Jens, 2011, In: British Journal of Nutrition. 105, 1, p. 54-61 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Reply to Hemilä by Lykkesfeldt and Poulsen
Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2011, In: British Journal of Nutrition. 105, 3, p. 488 1 p.
Research output: Contribution to journal › Letter › Research › peer-review
Published
Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components
Kücükakin, B., Kocak, V., Lykkesfeldt, Jens, Nielsen, H. J., Magnussen, K., Rosenberg, Jacob & Gögenür, I., 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 4, p. 299-303 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice
Rune, Ida, Ellekilde, M., Hansen, Camilla Hartmann Friis, Nielsen, Dennis Sandris, Rolin, B. C., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2011. 1 p.
Research output: Contribution to conference › Poster › Research
Published
Vitamin C in human nutrition
Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2011, Vitamins in the prevention of human diseases. Herrmann, W. & Obeid, R. (eds.). De Gruyter, p. 323-362 40 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
2010
Published
Antioxidant supplementation does not alter endurance training adaptation
Yfanti, C., Åkerström, T., Nielsen, S., Nielsen, A. R., Mounier, R., Mortensen, Ole Hartvig, Lykkesfeldt, Jens, Rose, A. J., Fischer, C. P. & Pedersen, Bente Klarlund, 1 Jul 2010, In: Medicine and Science in Sports and Exercise. 42, 7, p. 1388-95 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Is vitamin C supplementation beneficial? lessons learned from randomised controlled trials
Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2010, In: British Journal of Nutrition. 103, 9, p. 1251-1259 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture
Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2010, In: Analytical Biochemistry. 397, 1, p. 135-137 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo-controlled trial
Kücükakin, B., Klein, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenür, I., 2010, In: Acta Anaesthesiologica Scandinavica. 54, 9, p. 1121-1127 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial
Kücükakin, B., Wilhelmsen, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenur, I., 2010, In: European Journal of Vascular and Endovascular Surgery. 40, 4, p. 461-467 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Obese Prone Rats on high- and low-fat diets gain weight equally
Christensen, B. T., Hellgren, L., Sejrsen, K., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2010.
Research output: Contribution to conference › Poster › Research
2009
Published
C-Vitamin mod åreforkalkning
Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2009, In: Aktuel Naturvidenskab. 3, p. 26-29 4 p.
Research output: Contribution to journal › Journal article › Communication
Published
Does vitamin C deficiency result in impaired brain development in infants?
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2009, In: Redox Report. 14, 1, p. 2-6 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Poor vitamin C status is associated with increased carotid intima-media thickness, decreased microvascular function, and delayed myocardial repolarization in young patients with type 1 diabetes
Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2009, In: American Journal of Clinical Nutrition. 90, 2, p. 447-452 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Role of marginal vitamin C deficiency in atherogenesis: In vivo models and clinical studies
Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2009, In: Basic & Clinical Pharmacology & Toxicology. 104, 6, p. 419-433 15 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs
Tveden-Nyborg, Pernille, Jensen, Louise Kruse, Raida, Z., Villumsen, C. K., Larsen, J. O. & Lykkesfeldt, Jens, 2009, In: American Journal of Clinical Nutrition. 90, 3, p. 540-546 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2008
Published
Carotid Artery Intima-Media Thickness and Cutaneous Microvascular Function are Associated With Vitamin C Levels in Young Patients With Type 1 Diabetes
Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2008, Scientific Sessions 2008.
Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research
Published
Does vitamin C matter? A quest for in vivo effects of vitamin C deficiency
Lykkesfeldt, Jens, 2008, In: Free Radical Research. 42, S1, p. s23 1 p.
Research output: Contribution to journal › Conference abstract in journal › Research
Published
Morphine reduces spinal c-fos expression dose-dependently during experimental laparotomy in pigs: a combined pharmacokinetic and surgical study
Lykkegaard, K., Lykkesfeldt, Jens, Lauritzen, B. & Svendsen, O., 2008, In: Research in Veterinary Science. 84, 3, p. 457-464 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Utility of melatonin to treat surgical stress after major vascular surgery - a safety study
Kücükakin, B., Lykkesfeldt, Jens, Nielsen, H. J., Reiter, R. J., Rosenberg, Jacob & Gögenur, Ismail, 2008, In: Journal of Pineal Research. 44, 4, p. 426-431 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2007
Published
Ascorbate and dehydroascorbic acid as reliable biomarkers of oxidative stress: analytical reproducibility and long-term stability of plasma samples subjected to acidic deproteinization
Lykkesfeldt, Jens, 2007, In: Cancer Epidemiology, Biomarkers & Prevention. 16, 11, p. 2513-2516 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking: invited critical review
Lykkesfeldt, Jens, 2007, In: Clinica Chimica Acta. 380, 1-2, p. 50-58 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidants and antioxidants in disease: oxidative stress in farm animals
Lykkesfeldt, Jens & Svendsen, O., 2007, In: Veterinary Journal. 173, 3, p. 502-511 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative stress and damage in liver, but not in brain, of Fischer 344 rats subjected to dietary iron supplementation with lipid-soluble[(3,5,5-Trimethylhexanoyl)ferrocene]
Lykkesfeldt, Jens, Morgan, E., Christen, S., Skovgaard, L. T. & Moos, T., 2007, In: Journal of Biochemical and Molecular Toxicology (Print Edition). 21, 3, p. 145-155 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C deficiency in weanling guinea pigs: differential expression of oxidative stress and DNA repair in liver and brain
Lykkesfeldt, Jens, Trueba, G. P., Poulsen, H. E. & Christen, S., 2007, In: British Journal of Nutrition. 98, 6, p. 1116-1119 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2006
Published
Pharmacokinetics of amoxicillin administered in drinking water to recently weaned 3- to 4-week-old pigs with diarrhea experimentally induced by Escherichia coli O149:F4
Jensen, G. M., Lykkesfeldt, Jens, Frydendahl, K., Møller, K. & Svendsen, O., 2006, In: American Journal of Veterinary Research. 67, 4, p. 648-653 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Smoking depletes vitamin C: should smokers be recommended to take supplements?
Lykkesfeldt, Jens, 2006, Cigarette smoke and oxidative stress. Halliwell, B. B. & Poulsen, H. E. (eds.). Berlin: Kluwer Academic Publishers, p. 236-258 23 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
2005
Published
Age-dependent change in Vitamin C status: a phenomenon of matruration rather than of ageing
Lykkesfeldt, Jens & Moos, T., 2005, In: Mechanisms of Ageing and Development. 126, 8, p. 892-898 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of heparin-binding protein (CAP37/azurocidin) in a porcine model of Actinobacillus pleuropneumoniae-induced pneumonia
Lauritzen, B., Lykkesfeldt, Jens, Djurup, R., Flodgaard, H. & Svendsen, O., 2005, In: Pharmacological Research. 51, 6, p. 509-514 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Electroencephalographic changes after pediatric cardiac surgery with cardiopulmonary bypass: is slow wave activity unfavorable?
Schmitt, B., Finckh, B., Christen, S., Lykkesfeldt, Jens, Schmid, E. R., Bauersfeld, U., Critelli, H., Hajnal, B. L., Gessler, P. & Molinari, L., 2005, In: Pediatric Research. 58, 4, p. 771-778 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Evaluation of a single dose versus a divided dose regimen of amoxycillin in treatment of Actinobacillus pleuropneumoniae infection in pigs
Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2005, In: Research in Veterinary Science. 79, 1, p. 61-67 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation
Christen, S., Finckh, B., Lykkesfeldt, Jens, Gessler, P., Frese-Schaper, M., Nielsen, P., Schmid, E. R. & Schmitt, B., 2005, In: Free Radical Biology & Medicine. 38, 10, p. 1323-1332 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C: as biomarker and treatment of oxidative stress caused by smoking : methodological and clinical studies
Lykkesfeldt, Jens, 2005, Copenhagen: Center for Skov, Landskab og Planlægning/Københavns Universitet. 59 p.
Research output: Book/Report › Doctoral thesis › Research
2004
Published
Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone
Böttcher, T., Ren, H., Goiny, M., Gerber, J., Lykkesfeldt, Jens, Kuhnt, U., Lotz, M., Bunkowski, S., Werner, C., Schau, I., Spreer, A., Christen, S. & Nau, R., 2004, In: Journal of Neurochemistry. 91, 6, p. 1450-1460 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men 1-3
Turnlund, J. R., Jacob, R. A., Keen, C. L., Strain, J. J., Kelly, D. S., Domek, J. M., Keyes, W. R., Ensunsa, J. L., Lykkesfeldt, Jens & Coulter, J., 2004, In: American Journal of Clinical Nutrition. 79, 6, p. 1037-1044 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Optimized treatment regimens for enrofloxacin in pigs limits selection for resistance in salmonella and coliforms
Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2004. 1 p.
Research output: Contribution to conference › Paper › Research
Published
Pharmacokinetics of amoxicillin after oral administration in recently weaned piglets with experimentally induced Escherichia coli subtype O149:F4 diarrhea
Jensen, G. M., Lykkesfeldt, Jens, Frydendahl, K., Møller, K. & Svendsen, O., 2004, In: American Journal of Veterinary Research. 65, p. 992-995 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Plasma malondialdehyde is induced by smoking: a study with balanced antioxidant profiles
Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2004, In: British Journal of Nutrition. 92, 2, p. 203-206 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C and oxidative damage to DNA: chapter 11
Poulsen, Henrik Enghusen, Møller, P., Lykkesfeldt, Jens, Weimann, A. & Loft, S., 2004, Vitamin C. Asard, H., May, J. M. & Smirnoff, N. (eds.). Oxford: BIOS Scientific Publishers, p. 189-202 14 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
Published
Vitamin C pharmacokinetics of plain and slow release formulations in smokers
Viscovich, M., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2004, In: Clinical Nutrition. 23, 5, p. 1043-1050 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Vitamin C supplementation decreases oxidative DNA damage in mononuclear bood cells of smokers
Møller, P., Viscovich, M., Lykkesfeldt, Jens, Loft, S., Jensen, A. & Poulsen, H. E., 2004, In: European Journal of Nutrition. 43, p. 267-274 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2003
Published
Ascorbic acid recycling in human erythrocytes is induced by smoking in vivo
Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2003, In: Free Radical Biology & Medicine. 11, 11, p. 1439-1447 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of smoking on erythorbic acid pharmacokinetics
Lykkesfeldt, Jens, Bolbjerg, M. L. & Poulsen, H. E., 2003, In: British Journal of Nutrition. 89, 5, p. 667-671 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Evaluation of a single dose versus a divided dose regimen of danofloxacin in treatment of Actinobacillus pleuropneumoniae infection in pigs
Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 271-277 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Putative biomarkers for evaluating antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection
Lauritzen, B., Lykkesfeldt, Jens, Skaanild, M. T., Angen, Ø., Nielsen, Jens Peter & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 261-270 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs
Wiuff, C., Lykkesfeldt, Jens, Svendsen, O. & Aarestrup, F. M., 2003, In: Research in Veterinary Science. 75, 3, p. 185-193 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2002
Published
Biomarkers in evaluation of antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection
Lauritzen, B., Lykkesfeldt, Jens, Angen, Ø., Nielsen, Jens Peter & Friis, C., 2002.
Research output: Contribution to conference › Paper › Research
Published
Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis
Schaper, M., Gergely, S., Lykkesfeldt, Jens, Zbären, J., Leib, S. L., Täuber, M. G. & Christen, S., 2002, In: Journal of Neuropathology and Experimental Neurology. 61, 7, p. 605-613 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Distribution of enrofloxacin in intestinal tissue and contents of healthy pigs after oral and intramuscular administrations
Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2002, In: Journal of Veterinary Pharmacology and Therapeutics. 25, 5, p. 335-342 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Evaluation of a single dose and a split-dose regimen of danofloxacin against Actinobacillus pleuropneumoniae infection in pigs
Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2002.
Research output: Contribution to conference › Paper › Research
Published
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
Hagen, T. M., Liu, J., Lykkesfeldt, Jens, Wehr, C. M., Ingersoll, R. T., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 4, p. 1870-1875 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation
Jiang, Q., Lykkesfeldt, Jens, Shigenaga, M. K., Shigeno, E. T., Christen, S. & Ames, B. N., 2002, In: Free Radical Biology & Medicine. 33, 11, p. 1534-1542 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Increased oxidative damage in vitamin C deficiency is accompanied by induction of ascorbic acid recycling capacity in young but not mature guinea pigs
Lykkesfeldt, Jens, 2002, In: Free Radical Research. 36, 5, p. 567-574 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Measurement of ascorbic acid and dehydroascorbic acid in biological samples
Lykkesfeldt, Jens, 2002, Current protocols in toxicology. Maines, M., Costa, L. G., Hodson, E., Reed, D. J. & Sipes, I. G. (eds.). New York: Wiley, p. 7.6.1-7.6.15 15 p.
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
2001
Published
Determination of malondialdehyde as dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: comparison with ultraviolet-visible spectrophotometry
Lykkesfeldt, Jens, 2001, In: Clinical Chemistry. 47, 9, p. 1725-1727 3 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Determination of the disappearance rate of iodine-125 labelled oils from the injection site after intramuscular and subcutaneous administration to pigs
Weng Larsen, S., Reinvar, E., Svendsen, O., Lykkesfeldt, Jens, Friis, G. J. & Larsen, C., 2001, In: Internation Journal of Pharmaceutics. 230, p. 67-75 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment
Christen, S., Schaper, M., Lykkesfeldt, Jens, Siegenthaler, C., Bifrare, Y., Banic, S. O., Leib, S. L. & Täuber, M. G., 2001, In: Free Radical Biology & Medicine. 31, 6, p. 754-762 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
2000
Published
Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes
Lykkesfeldt, Jens, Christen, S., Wallock, L. M., Chang, H. H., Jacob, R. A. & Ames, B. N., 2000, In: American Journal of Clinical Nutrition. 71, p. 530-6 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Biochemical markers as indicators of the efficiency of antibiotic treatment of Actinobacillus pleuropneumoniae infection in pigs
Lauritsen, B., Lykkesfeldt, Jens, Angen, Ø. & Friis, C., 2000. 1 p.
Research output: Contribution to conference › Paper › Research
Published
Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride
Lykkesfeldt, Jens, 2000, In: Analytical Biochemistry. 282, p. 89-93 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Morphine concentration in plasma andcerebrospinal fluid in the anaesthetised pig after a single intravenous administration
Lykkegaard, K., Lykkesfeldt, Jens & Svendsen, O., 2000. 1 p.
Research output: Contribution to conference › Paper › Research
Published
On the possible connection between vitamin C, cardiovirus and guinea pig lameness
Clausen, F. B., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2000, Ikke angivet. Laboratory Animals Ltd, p. 101-104 4 p.
Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
1999
Published
(R)-α-Lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate
Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 16 Feb 1999, In: FASEB Journal. 13, 2, p. 411-418 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
(R)-alfa-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate
Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 1999, In: The FASEB Journal. 13, p. 411-4418 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age
Lykkesfeldt, Jens & Ames, B. N., 1999, In: Methods in Enzymology. 299, p. 83-88 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age
Lykkesfeldt, Jens & Ames, B. N., 1999, Oxidants and antioxidants part A. Packer, L. (ed.). San Diego: Academic Press, Vol. 299. p. 83-88 6 p. (Methods in Enzymology).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
1998
Published
Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: Decline with age
Lykkesfeldt, Jens & Ames, B. N., 3 Nov 1998, In: Methods in Enzymology. 299, p. 83-88 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Artemisinin induces omeprazole metabolism in human beings
Svensson, U. S. H., Ashton, M., Hai, T. N., Bertilsson, L., Huong, D. X., Van Huong, N., Niêu, N. T., Sy, N. D., Lykkesfeldt, Jens & Công, L. D., 1 Aug 1998, In: Clinical Pharmacology and Therapeutics. 64, 2, p. 160-167 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity
Hagen, T. M., Ingersoll, R. T., Wehr, C. M., Lykkesfeldt, Jens, Vinarsky, V., Bartholomew, J. C., Song, M. & Ames, B. N., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, p. 9562-9566 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes: reversal with (R)-alfa-lipoic acid supplementation
Lykkesfeldt, Jens, Hagen, T. M., Vinarsky, V. & Ames, B. N., 1998, In: The FASEB Journal. 12, p. 1183-1189 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative DNA damage in vivo: relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion
Poulsen, H. E., Loft, S., Prieme, H., Vistisen, K., Lykkesfeldt, Jens, Nyyssonen, K. & Salonen, J. T., 1998, In: Free Radical Research. 29, p. 565-571 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Oxidative DNA damage in vivo: Relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion
Poulsen, Henrik Enghusen, Loft, Steffen, Prieme, H., Vistisen, K. K., Lykkesfeldt, Jens, Nyyssonen, K. & Salonen, J. T., 1998, In: Free Radical Research. 29, p. 565-571
Research output: Contribution to journal › Journal article › Research › peer-review
1997
Published
Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking, 1-3
Lykkesfeldt, Jens, Loft, Steffen, Nielsen, J. B. & Poulsen, Henrik Enghusen, 1997, In: American Journal of Clinical Nutrition. 65, p. 959-963
Research output: Contribution to journal › Journal article › Research › peer-review
1996
Published
Effect of smoking cessation on plasma ascorbic acid concentration
Lykkesfeldt, Jens, Priemé, H., Loft, Steffen & Poulsen, Henrik Enghusen, 13 Jul 1996, In: B M J (Clinical Research Edition). 313, 7049, p. 91
Research output: Contribution to journal › Journal article › Research › peer-review
1995
Published
Involvement of cytochrome P450 in oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomal enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba L.
Du, L., Lykkesfeldt, Jens, Olsen, C. E. & Halkier, Barbara Ann, 19 Dec 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 26, p. 12505-12509 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Determination of Ascorbic Acid and Dehydroascorbic Acid in Plasma by High-Performance Liquid Chromatography with Coulometric Detection - Are They Reliable Biomarkers of Oxidative Stress?
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1995, In: Analytical Biochemistry. 229, p. 329-335
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Involvment of cytochrome P450 in Oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomale enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba
Du, L., Lykkesfeldt, Jens, Olsen, C. E. & Halkier, B. A., 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine
Rasmussen, B. B., Mäenpää, J., Pelkonen, O., Loft, Steffen, Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Brøsen, K., 1995, In: British Journal of Clinical Pharmacology. 39, p. 151-159
Research output: Contribution to journal › Journal article › Research › peer-review
1994
Published
Simultaneous determination of urinary free cortisol and 6β-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 3 Oct 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, 1, p. 23-29 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Simultaneous determination of urinary free cortisol and 6*Gb-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, p. 23-29
Research output: Contribution to journal › Journal article › Research › peer-review
1993
Published
Nitrosamindannende håndkøbspraeparater?
Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 13 Dec 1993, In: Ugeskrift for Laeger. 155, 50, p. 4106-4107 2 p.
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published
Synthesis of benzylglucosinolate in Tropaeolum majus L. Isothiocyanates as potent enzyme inhibitors
Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1993, In: Plant Physiology. 102, 2, p. 609-613 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
1991
Published
2-Nitro-3-(p-hydroxyphenyl)propionate and aci-1-nitro-2-(p-hydroxyphenyl)ethane, two intermediates in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench
Halkier, Barbara Ann, Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 2, p. 487-491 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review

ID: 4231856

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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Research output: Contribution to journal › Journal article › Research › peer-review
Published
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
Published
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
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Published

Jens Lykkesfeldt

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