Hannelouise Kissow

Hannelouise Kissow

Associate Professor


  1. 2000
  2. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2001
  4. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection

    Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Jeppesen, Palle Bekker, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46, 2, p. 379-88 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. 2002
  6. Published

    Immunoneutralization of endogenous glucagon-like peptide-2 reduces adaptive intestinal growth in diabetic rats.

    Hartmann, B., Thulesen, J., Hare, K. J., Kissow, Hannelouise, Orskov, C., Poulsen, Steen Seier & Holst, Jens Juul, 2002, In: Regulatory Peptides. 105, 3, p. 173-9 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist.

    Thulesen, J., Knudsen, L. B., Hartmann, B., Hastrup, S., Kissow, Hannelouise, Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2002, In: Regulatory Peptides. 103, 1, p. 9-15 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. 2003
  9. Published

    Injected TFF1 and TFF3 bind to TFF2-immunoreactive cells in the gastrointestinal tract in rats

    Poulsen, Steen Seier, Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Nexø, E. & Thim, L., 2003, In: Regulatory Peptides. 115, 2, p. 91-99 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. 2004
  11. Published

    Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice

    Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. 2005
  13. Published

    Luminal and parenteral TFF2 and TFF3 dimer and monomer in two models of experimental colitis in the rat.

    Poulsen, Steen Seier, Kissow, Hannelouise, Hare, K., Hartmann, B. & Thim, L., 2005, In: Regulatory Peptides. 126, 3, p. 163-71 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. 2007
  15. Published

    The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.

    Hare, K. J., Hartmann, B., Kissow, Hannelouise, Holst, Jens Juul & Poulsen, Steen Seier, 2007, In: Clinical Cancer Research. 13, 17, p. 5170-5 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. 2011
  17. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

    Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, GIANT Consortium, G. C., 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain

    Ugleholdt, Randi Kjærsgaard, Pedersen, Jens, Bassi, Maria Rosaria, Füchtbauer, E., Jørgensen, S. M., Kissow, Hannelouise, Nytofte, N., Poulsen, Steen Seier, Rosenkilde, Mette, Seino, Y., Thams, P., Holst, Peter Johannes & Holst, Jens Juul, Dec 2011, In: The Journal of Biological Chemistry. 286, 52, p. 44632-44645 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. 2012
  20. Published

    Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine

    Kissow, Hannelouise, Viby, N., Hartmann, Bolette, Holst, Jens Juul, Timm, M., Thim, L. & Poulsen, Steen Seier, 2012, In: Cancer Chemotherapy and Pharmacology. Supplement. 70, 1, p. 39-48 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Glucagon-like peptide-1 as a treatment for chemotherapy-induced mucositis

    Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul & Poulsen, Steen Seier, 20 Oct 2012, In: Gut.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice

    Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. 2013
  24. Published

    Glucagon-like peptide-1 (GLP-1) reduces mortality and improves lung function in a model of experimental obstructive lung disease in female mice

    Viby, N., Isidor, Marie Sophie, Buggeskov, K. B., Poulsen, Steen Seier, Hansen, Jacob B. & Kissow, Hannelouise, 2013, In: Endocrinology. 154, 12, p. 4503-4511 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    The Carcinogenic Agent Azoxymethane (AOM) Enhances Early Inflammation-induced Colon Crypt Pathology

    Venning, F. A., Claesson, Mogens Helweg & Kissow, Hannelouise, 2013, In: Journal of Cancer Science & Therapy. 5, 11, p. 377-383 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. 2015
  27. Published

    Glucagon-like peptides 1 and 2: intestinal hormones implicated in the pathophysiology of mucositis

    Kissow, Hannelouise, 2015, In: Current Opinion in Supportive and Palliative Care. 9, 2, p. 196-202 7 p.

    Research output: Contribution to journalReviewpeer-review

  28. Published

    Trefoil factors (TFFs) are increased in bronchioalveolar lavage fluid from patients with chronic obstructive lung disease (COPD)

    Viby, N., Nexø, E., Kissow, Hannelouise, Andreassen, H., Clementsen, P., Thim, L. & Poulsen, Steen Seier, Jan 2015, In: Peptides. 63, p. 90-95 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

    Jensen, E. P., Poulsen, Steen Seier, Kissow, Hannelouise, von Holstein-Rathlou, Niels-Henrik, Deacon, Carolyn F., Jensen, B. L., Holst, Jens Juul & Sorensen, Charlotte Mehlin, 15 Apr 2015, In: A J P: Renal Physiology (Online). 308, 8, p. F867-F877 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Bovine colostrum modulates myeloablative chemotherapy-induced gut toxicity in piglets

    Pontoppidan, P. E. L., Shen, René Liang, Cilieborg, Malene Skovsted, Jiang, Pingping, Kissow, Hannelouise, Petersen, B. L., Thymann, Thomas, Heilmann, C., Muller, Klaus & Sangild, Per Torp, Jul 2015, In: Journal of Nutrition. 145, 7, p. 1472-1480 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Trefoil factor peptides in serum and sputum from subjects with asthma and COPD

    Viby, N., Pedersen, L., Lund, T. K., Kissow, Hannelouise, Backer, Vibeke, Nexø, E., Thim, L. & Poulsen, Steen Seier, Jul 2015, In: Clinical Respiratory Journal. 9, 3, p. 322-329 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. 2016
  33. Published

    Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. 2017
  35. Published

    Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction

    Kyhl, K., Lønborg, J., Hartmann, Bolette, Kissow, Hannelouise, Poulsen, Steen Seier, El Ali, Henrik H., Kjær, Andreas, Dela, Flemming, Engstrøm, Thomas & Treiman, M., 2017, In: Peptides. 93, p. 1-12

    Research output: Contribution to journalJournal articlepeer-review

  36. Published
  37. 2018
  38. Published

    Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice

    Yassin, M., Kissow, Hannelouise, Vainer, B., Joseph, P. D., Hay-Schmidt, Anders, Olsen, J. & Pedersen, Anders Elm, 2018, In: Scientific Reports. 8, p. 1-16 6905.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

    Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen Seier, Vilstrup, H., Prehn, C., Adamski, J., Jepsen, Sara Lind, Hartmann, Bolette, Dal, Jenna Elizabeth Hunt, Charron, M. J., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E93-E103

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Endogenous glucagon-like peptide- 1 and 2 are essential for regeneration after acute intestinal injury in mice

    Hytting-Andreasen, R., Balk-Møller, E., Hartmann, Bolette, Pedersen, Jens, Windeløv, Johanne Agerlin, Holst, Jens Juul & Kissow, Hannelouise, 2018, In: PLoS ONE. 13, 6, p. 1-14 e0198046.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Rectal insulin instillation inhibits inflammation and tumor development in chemically-induced colitis

    Yassin, M., Sadowska, Z., Tritsaris, Katerina, Kissow, Hannelouise, Hansen, Camilla Hartmann Friis, Forman, Julie Lyng, Rogler, G., Troelsen, J. T., Pedersen, Anders Elm & Olsen, Jørgen, 2018, In: Journal of Crohn's and Colitis. 12, 12, p. 1459–1474 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    The Intestinotrophic Effects of Glucagon-Like Peptide-2 in Relation to Intestinal Neoplasia

    Orhan, Adile, Gögenur, Ismail & Kissow, Hannelouise, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 8, p. 2827-2837

    Research output: Contribution to journalReviewpeer-review

  43. Published

    Stimulation of the Bile Acid Receptor Tgr5 Promotes Intestinal Growth

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 1 May 2018, In: Gastroenterology. 154, 6 (S1), 1 p., S-333.

    Research output: Contribution to journalConference abstract in journal

  44. 2019
  45. Published

    Animal models of mucositis: critical tools for advancing pathobiological understanding and identifying therapeutic targets

    Wardill, H. R., Tissing, W. J. E., Kissow, Hannelouise & Stringer, A. M., 2019, In: Current Opinion in Supportive and Palliative Care. 13, 2, p. 119-133

    Research output: Contribution to journalReviewpeer-review

  46. Published

    Glepaglutide, a novel long-acting glucagon-like peptide-2 analogue, for patients with short bowel syndrome: a randomised phase 2 trial

    Naimi, R. M., Hvistendahl, M., Enevoldsen, L. H., Madsen, J. L., Fuglsang, S., Poulsen, Steen Seier, Kissow, Hannelouise, Pedersen, Jens, Nerup, N., Ambrus, R., Achiam, Michael Patrick, Svendsen, L. B., Holst, Jens Juul, Hartmann, Bolette, Hansen, S. H., Dragsted, Lars Ove, Steensberg, A., Mouritzen, U., Hansen, M. B. & Jeppesen, Palle Bekker, 2019, In: The Lancet Gastroenterology and Hepatology. 4, 5, p. 354-363 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Glucagon-like peptide-1 is a marker of systemic inflammation in patients treated with high-dose chemotherapy and autologous stem cell transplantation

    Ebbesen, M. S., Kissow, Hannelouise, Hartmann, Bolette, Grell, Kathrine, Gørløv, J. S., Kielsen, K., Holst, Jens Juul & Muller, Klaus, 2019, In: Biology of Blood and Marrow Transplantation. 25, 6, p. 1085-1091 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Dietary Fiber is Essential to Maintain L Cell Secretion and Intestinal Weight

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), p. S-477

    Research output: Contribution to journalConference abstract in journal

  49. Published
  50. Published

    Important Endpoints and Proliferative Markers to Assess Small Intestinal Injury and Adaptation using a Mouse Model of Chemotherapy-Induced Mucositis

    Billeschou, Anna, Dal, Jenna Elizabeth Hunt & Kissow, Hannelouise, 12 May 2019, In: Journal of visualized experiments : JoVE. 147, e59236.

    Research output: Contribution to journalJournal articlepeer-review

  51. 2020
  52. Published

    Glucagon-Like Peptide 1 and Atrial Natriuretic Peptide in a Female Mouse Model of Obstructive Pulmonary Disease

    Balk-Møller, E., Windeløv, Johanne Agerlin, Svendsen, B., Dal, Jenna Elizabeth Hunt, Ghiasi, S. M., Sorensen, Charlotte Mehlin, Holst, Jens Juul & Kissow, Hannelouise, 2020, In: Endocrine Research. 4, 1, 19 p., bvz034.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Minimizing Cardiac Oedema during Ex Vivo Perfusion in a Juvenile Porcine Model - How Much Does Coronary Flow Matter?

    Qazi, S., Møller, Christian H., Hebsgaard, M., Kissow, Hannelouise, Lilleør, N. & Olsen, P. S., 2020, In: Journal of Heart and Lung Transplantation. 39, 4 Suppl., p. 354-354 885.

    Research output: Contribution to journalConference abstract in journalpeer-review

  54. Published

    Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2 dependent pathway in mice

    Dal, Jenna Elizabeth Hunt, Billeschou, Anna, Windeløv, Johanne Agerlin, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 6, p. G980-G987

    Research output: Contribution to journalJournal articlepeer-review

  55. 2021
  56. Published
  57. Published

    Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Schoonjans, K., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 10 p., 640602.

    Research output: Contribution to journalJournal articlepeer-review

  58. Published

    GLP-1 and Intestinal Diseases

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul, Jeppesen, Palle Bekker & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 4, 14 p., 383.

    Research output: Contribution to journalReviewpeer-review

  59. Published

    Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation

    Sørum, Maria Ebbesen, Kissow, Hannelouise, Hartmann, Bolette, Kielsen, K., Sørensen, K., Stinson, Sara, Frithioff-Bojsoe, C., Fonvig, Cilius Esmann, Holm, Jens-Christian, Hansen, Torben, Holst, Jens Juul & Müller, K. G., 2021, In: Frontiers in Immunology. 12, 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Intestinal Adaptation upon Chemotherapy-Induced Intestinal Injury in Mice Depends on GLP-2 Receptor Activation

    Billeschou, Anna, Dal, Jenna Elizabeth Hunt, Ghimire, A., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 1, 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 7 p., 695145.

    Research output: Contribution to journalJournal articlepeer-review

  62. Published

    Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

    Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

    Research output: Contribution to journalJournal articlepeer-review

  63. 2022
  64. Published

    Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial

    Hvistendahl, M. K., Naimi, R. M., Hansen, S. H., Rehfeld, Jens Frederik, Kissow, Hannelouise, Pedersen, Jens, Dragsted, Lars Ove, Sonne, D. P., Knop, Filip Krag & Jeppesen, Palle Bekker, 2022, In: Journal of Parenteral and Enteral Nutrition. 46, 4, p. 923-935 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  65. Published
  66. Published

    Glucagon-like peptide-1 stimulates acute secretion of pro-atrial natriuretic peptide from the isolated, perfused pig lung exposed to warm ischemia

    Balk-Møller, E., Hebsgaard, M. M. B., Lilleør, N. B., Møller, Christian H., Goetze, Jens P. & Kissow, Hannelouise, 2022, In: Frontiers in Transplantation. 1, 11 p., 1082634.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

    Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    Tolerable Duration of Warm Ischaemia After Circulatory Death Is Safe For At Least One Hour in Porcine Lungs: Functional Assessment with Ex Vivo Lung Perfusion

    Hebsgaard, M. M. B., Kissow, Hannelouise, Lilleør, N. B., Lorenzen, U. S., Chemtob, R. A., Møller-Sørensen, H., Olsen, P. S. & Møller, Christian H., 2022, In: Heart Surgery Forum. 25, 1, p. E48-E52 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  69. 2023
  70. Published

    Effects of glepaglutide, a long-acting glucagon-like peptide-2 analog, on intestinal morphology and perfusion in patients with short bowel syndrome: Findings from a randomized phase 2 trial

    Naimi, R. M., Hvistendahl, M. K., Poulsen, Steen Seier, Kissow, Hannelouise, Pedersen, Jens, Nerup, N. A., Ambrus, R., Achiam, Michael Patrick, Svendsen, Lars Bo & Jeppesen, Palle Bekker, 2023, In: Journal of Parenteral and Enteral Nutrition. 47, 1, p. 140-150

    Research output: Contribution to journalJournal articlepeer-review

  71. Published
  72. Published

ID: 925016