David Paul Drucker Woldbye

David Paul Drucker Woldbye

Associate Professor

ORCID: 0000-0002-6321-3850

Publication year:
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1 - 25 out of 138Page size: 25
  1. 2023
  2. Published

    Combinatorial gene therapy for epilepsy: Gene sequence positioning and AAV serotype influence expression and inhibitory effect on seizures

    Melin, Esbjörn Aage Anders, Andersson, M., Gøtzsche, C. R., Wickham, J., Huang, Y., Szczygiel, Julia Alicja, Boender, A., Christiansen, S. H., Pinborg, Lars Hageman, Woldbye, David Paul Drucker & Kokaia, M., 2023, In: Gene Therapy. 30, p. 649-658 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Differential Expression of the β3 Subunit of Voltage-Gated Ca2+ Channel in Mesial Temporal Lobe Epilepsy

    Kjær, C., Palasca, Oana, Barzaghi, G., Bak, Lasse Kristoffer, Durhuus, R. K. J., Jakobsen, Emil, Pedersen, Louise, Bartels, Emil Daniel, Woldbye, David Paul Drucker, Pinborg, Lars Hageman & Jensen, Lars Juhl, 2023, In: Molecular Neurobiology. 60, p. 5755–5769

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2022
  5. Published

    GDNF Increases Inhibitory Synaptic Drive on Principal Neurons in the Hippocampus via Activation of the Ret Pathway

    Mikroulis, A., Waloschková, E., Bengzon, J., Woldbye, David Paul Drucker, Pinborg, Lars Hageman, Jespersen, B., Avila, A. S., Laszlo, Z. I., Henstridge, C., Ledri, M. & Kokaia, M., 2022, In: International Journal of Molecular Sciences. 23, 21, 12 p., 13190.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Modeling the early stages of Alzheimer's disease by administering intracerebroventricular injections of human native A beta oligomers to rats

    Baerends, E., Soud, K., Folke, J., Pedersen, Anna-Kathrine, Henmar, S., Konrad, Lisa, Lycas, M. D., Mori, Yuki, Pakkenberg, B., Woldbye, David Paul Drucker, Dmytriyeva, O. & Pankratova, Stanislava, 2022, In: Acta Neuropathologica Communications. 10, 1, 21 p., 113.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Neuroglobin deficiency increases seizure susceptibility but does not affect basal behavior in mice

    Gotzsche, C. R., Woldbye, David Paul Drucker, Hundahl, C. A. & Hay-Schmidt, Anders, 2022, In: Journal of Neuroscience Research. 100, 10, p. 1921-1932 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2021
  9. Published

    Current and Future Prospects for Gene Therapy for Rare Genetic Diseases Affecting the Brain and Spinal Cord

    Jensen, T. L., Gøtzsche, C. R. & Woldbye, David Paul Drucker, 2021, In: Frontiers in Molecular Neuroscience. 14, 27 p., 695937.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation

    Sørensen, G., Rickhag, Karl Mattias, Leo, D., Lycas, M. D., Ridderstrøm, P. H., Weikop, P., Lilja, J. H., Rifes, P., Herborg, Freja, Woldbye, David Paul Drucker, Wörtwein, Gitta, Gainetdinov, R. R., Fink-Jensen, Anders & Gether, Ulrik, 2021, In: Journal of Biological Chemistry. 297, 6, 101361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Editorial: Gene Therapy in the CNS – Progress and Prospects for Novel Therapies

    Ledri, M., Sørensen, Andreas Toft, Kokaia, M., Woldbye, David Paul Drucker & Gøtzsche, C. R., 2021, In: Frontiers in Molecular Neuroscience. 14, 778134.

    Research output: Contribution to journal › Editorial › Research › peer-review

  12. Published

    Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

    Forstner, A. J., Awasthi, S., Wolf, C., Maron, E., Erhardt, A., Czamara, D., Eriksson, E., Lavebratt, C., Allgulander, C., Friedrich, N., Becker, J., Hecker, J., Rambau, S., Conrad, R., Geiser, F., Mcmahon, F. J., Moebus, S., Hess, T., Buerfent, B. C., Hoffmann, P. & 55 others, Herms, S., Heilmann-heimbach, S., Kockum, I., Olsson, T., Alfredsson, L., Weber, H., Alpers, G. W., Arolt, V., Fehm, L., Fydrich, T., Gerlach, A. L., Hamm, A., Kircher, T., Pané-farré, C. A., Pauli, P., Rief, W., Ströhle, A., Plag, J., Lang, T., Wittchen, H., Mattheisen, M., Meier, S., Metspalu, A., Domschke, K., Reif, A., Hovatta, I., Lindefors, N., Andersson, E., Schalling, M., Mbarek, H., Milaneschi, Y., De Geus, E. J. C., Boomsma, D. I., Penninx, B. W. J. H., Thorgeirsson, T. E., Steinberg, S., Stefansson, K., Stefansson, H., Müller-myhsok, B., Hansen, Thomas Folkmann, Børglum, A. D., Werge, Thomas, Mortensen, P. B., Nordentoft, Merete, Hougaard, D. M., Hultman, C. M., Sullivan, P. F., Nöthen, M. M., Woldbye, David Paul Drucker, Mors, O., Binder, E. B., Rück, C., Ripke, S., Deckert, J. & Schumacher, J., 2021, In: Molecular Psychiatry. 26, p. 4179–4190 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

    Johnsen, Cecilie Hundahl, Kotzbeck, P., Burm, Hayley Beth, Christiansen, S. H., Pedersen, Lola Julie Torz, zmw799, zmw799, Madsen, M. P., Ratner, C., Serup, A. K., Thompson, J. J., Eichmann, T. O., Pers, Tune H, Woldbye, David Paul Drucker, Piomelli, D., Kiens, Bente, Zechner, R., Skov, Louise Julie & Holst, Birgitte, 2021, In: Molecular Metabolism. 47, 16 p., 101174.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Retinal layer segmentation in rodent OCT images: Local intensity profiles & fully convolutional neural networks

    Morales, S., Colomer, A., Mossi, J. M., del Amor, R., Woldbye, David Paul Drucker, Klemp, Kristian, Larsen, M. & Naranjo, V., 2021, In: Computer Methods and Programs in Biomedicine. 198, 105788.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson's Disease

    Stokholm, K., Thomsen, M. B., Phan, J., Moller, L. K., Bay-Richter, C., Christiansen, S. H., Woldbye, David Paul Drucker, Romero-Ramos, M. & Landau, A. M., 2021, In: Biomedicines. 9, 12, 16 p., 1876.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats

    Szczygiel, Julia Alicja, Danielsen, K. I., Melin, E., Rosenkranz, S. H., Pankratova, Stanislava, Ericsson, A., Agerman, K., Kokaia, M. & Woldbye, David Paul Drucker, 2020, In: Frontiers in Molecular Neuroscience. 13, 13 p., 232.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Genterapi til sygdomme i centralnervesystemet

    Nissen, K., Klem, Louise Bomholt, Jeppesen, R., Axelsen, T. M., Christiansen, S. H., Gøtzsche, C. R., Pinborg, Lars Hageman, Jespersen, B., Klemp, Kristian & Woldbye, David Paul Drucker, 2020, In: Ugeskrift for Laeger. 182, 3, 6 p., V09190535.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Neuropeptide Y system mRNA expression changes in the hippocampus of a type I diabetes rat model

    Campos, E. J., Martins, J., Brudzewsky, D., Woldbye, David Paul Drucker & Ambrósio, A. F., 2020, In: Annals of Anatomy. 227, 8 p., 151419.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Neurotrophic effects of vascular endothelial growth factor B and novel mimetic peptides on neurons from the central nervous system

    Dmytriyeva, O., de Diego Ajenjo, Amaia, Jørgensen, Kathrine Lundø, Hertz, H., Rasmussen, K. K., Christiansen, A. T., Klingelhofer, J., Nielsen, A. L., Hoeber, J., Kozlova, E. N., Woldbye, David Paul Drucker & Pankratova, Stanislava, 2020, In: ACS Chemical Neuroscience. 11, 9, p. 1270–1282 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The dorsomedial hypothalamus and nucleus of the solitary tract as key regulators in a rat model of chronic obesity

    Zhang, C., Barkholt, P., Nielsen, J. C., Thorbek, D. D., Rigbolt, K., Vrang, N., Woldbye, David Paul Drucker & Jelsing, J., 2020, In: Brain Research. 1727, 146538.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2019
  23. Published

    Towards automatic glaucoma assessment: An Encoder-decoder CNN for Retinal Layer Segmentation in Rodent OCT images

    Del Amor, R., Morales, S., Colomer, A., Mossi, J. M., Woldbye, David Paul Drucker, Klemp, Kristian, Larsen, M. & Naranjo, V., Sep 2019, EUSIPCO 2019 - 27th European Signal Processing Conference. European Signal Processing Conference, EUSIPCO, (European Signal Processing Conference, Vol. 2019-September).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  24. Published

    Differential effects of chemogenetic inhibition on dopamine and norepinephrine neurons in the mouse 5-choice serial reaction time task

    Fitzpatrick, C. M., Runegaard, A. H., Christiansen, S. H., Hansen, Nikolaj Winther, Jørgensen, Søren Heide, McGirr, J. C., de Diego Ajenjo, Amaia, Sørensen, Andreas Toft, Perrier, Jean-Francois Marie, Petersen, A., Gether, Ulrik, Woldbye, David Paul Drucker & Andreasen T., Jesper, 2019, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90, 2, p. 264-276 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy

    Melin, E., Nanobashvili, A., Avdic, U., Gøtzsche, C. R., Andersson, M., Woldbye, David Paul Drucker & Kokaia, M., 2019, In: Molecular Therapy - Methods and Clinical Development. 15, p. 179-193 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients

    Wickham, J., Ledri, M., Bengzon, J., Jespersen, B., Pinborg, Lars Hageman, Englund, E., Woldbye, David Paul Drucker, Andersson, M. & Kokaia, M., 2019, In: Scientific Reports. 9, 11 p., 19393.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges

    Runegaard, A. H., Fitzpatrick, C. M., Woldbye, David Paul Drucker, Andreasen T., Jesper, Sørensen, Andreas Toft & Gether, Ulrik, 2019, In: Pharmacological Reviews. 71, 2, p. 123-156 34 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Short erythropoietin-derived peptide enhances memory, improves long-term potentiation, and counteracts amyloid beta-induced pathology

    Dmytriyeva, O., Belmeguenai, A., Bezin, L., Soud, K., Woldbye, David Paul Drucker, Gotzsche, C. R. & Pankratova, Stanislava, 2019, In: Neurobiology of Aging. 81, p. 88-101 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats

    Tillmann, S., Skibdal, H. E., Christiansen, S. H., Gøtzsche, C. R., Hassan, M., Mathe, A. A., Wegener, G. & Woldbye, David Paul Drucker, 2019, In: Behavioural Brain Research. 367, p. 28-34 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The C-terminal flanking peptide of neuropeptide Y (NPY) is not essential for seizure-suppressant actions of prepro-NPY overexpression in male rats

    Soud, K., Jørgensen, Søren Heide, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, 2019, In: Journal of Neuroscience Research. 97, 3, p. 362-372 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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