Cord Herbert Brakebusch

Cord Herbert Brakebusch

ORCID: 0000-0002-9342-1634

Publication year:
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1 - 100 out of 203Page size: 100
  1. 2024
  2. Published

    Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry

    Bock, F., Dong, X., Li, S., Viquez, O. M., Sha, E., Tantengco, M., Hennen, E. M., Plosa, E., Ramezani, A., Brown, K. L., Whang, Y. M., Terker, A. S., Arroyo, J. P., Harrison, D. G., Fogo, A., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2024, In: Science Advances. 10, 6, eadi7840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    A RhoA-mediated biomechanical response in Schwann cells modulates peripheral nerve myelination

    Seixas, A. I., Morais, M. R. G., Brakebusch, Cord Herbert & Relvas, J. B., 2023, In: Progress in Neurobiology. 227, 13 p., 102481.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation

    Martínez-Sánchez, L. D. C., Ngo, P. A., Pradhan, R., Becker, L-S., Boehringer, D., Soteriou, D., Kubankova, M., Schweitzer, C., Koch, T., Thonn, V., Erkert, L., Stolzer, I., Günther, C., Becker, C., Weigmann, B., Klewer, M., Daniel, C., Amann, K., Tenzer, S., Atreya, R. & 8 others, Bergo, M., Brakebusch, Cord Herbert, Watson, A. J. M., Guck, J., Fabry, B., Atreya, I., Neurath, M. F. & López-Posadas, R., 2023, In: Gut. 72, 2, p. 275-294 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance

    Socodato, R., Almeida, T. O., Portugal, C. C., Santos, E. C. S., Tedim-Moreira, J., Galvão-Ferreira, J., Canedo, T., Baptista, F. I., Magalhães, A., Ambrósio, A. F., Brakebusch, Cord Herbert, Rubinstein, B., Moreira, I. S., Summavielle, T., Pinto, I. M. & Relvas, J. B., 2023, In: Cell Reports. 42, 12, 28 p., 113447.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    RhoB promotes Salmonella survival by regulating autophagy

    Kirchenwitz, M., Halfen, J., von Peinen, K., Prettin, S., Kollasser, J., zur Lage, S., Blankenfeldt, W., Brakebusch, Cord Herbert, Rottner, K., Steffen, A. & Stradal, T. E. B., 2023, In: European Journal of Cell Biology. 102, 4, 17 p., 151358.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    RhoB promotesSalmonellasurvival by regulating autophagy

    Kirchenwitz, M., Halfen, J., Peinen, K. V., Prettin, S., Kollasser, J., Brakebusch, Cord Herbert, Rottner, K., Steffen, A. & Stradal, T. E. B., 2023, bioRxiv, 52 p.

    Research output: Working paper › Preprint › Research

  9. Published

    Two Transient Receptor Potential Channels at Focal Adhesions

    Mitsou, I., Carlson, C. R., Multhaupt, Hinke Arnolda B V H, Brakebusch, Cord Herbert & Couchman, John Robert, 2023, In: Journal of Histochemistry and Cytochemistry. 71, 9, p. 495-508 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2022
  11. Published

    Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo

    Herum, K. M., Weng, Guangzheng, Kahnert, Konstantin, Waikel, R., Milburn, G., Conger, A., Anaya, P., Campbell, K. S., Lundby, Alicia, Won, K. J. & Brakebusch, Cord Herbert, 2022, In: Matrix Biology Plus. 15, 100113.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth

    Ye, Z., Kilic, G., Dabelsteen, Sally, Marinova, I. N., Thøfner, J. F. B., Song, Ming, Levann, Asha Maria Rudjord, Bagdonaite, Ieva , Vakhrushev, Sergey, Brakebusch, Cord Herbert, Olsen, Jesper Velgaard & Wandall, Hans H., 2022, In: Science Signaling. 15, 761, eabo2206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Control of cortical cytoskeleton-membrane interaction by RhoA regulates peripheral nerve myelination

    Seixas, A. I., Morais, M. R. G., Brakebusch, Cord Herbert & Relvas, J. B., 2022, Cold Spring Harbor Laboratory, 15 p. (bioRxiv).

    Research output: Working paper › Preprint › Research

  14. Published

    The Essential Role of Rac1 Glucosylation in Clostridioides difficile Toxin B-Induced Arrest of G1-S Transition

    Petersen, L., Stroh, S., Schöttelndreier, D., Grassl, G. A., Rottner, K., Brakebusch, Cord Herbert, Fahrer, J. & Genth, H., 2022, In: Frontiers in Microbiology. 13, 11 p., 846215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells

    Vadakumchery, A., Faraidun, H., Ayoubi, O. E., Outaleb, I., Schmid, V., Abdelrasoul, H., Amendt, T., Khadour, A., Setz, C., Göhring, K., Lodd, K., Hitzing, C., Alkhatib, A., Bilal, M., Benckendorff, J., Al Shugri, A. K., Brakebusch, C. H., Engels, N., Datta, M., Hobeika, E. & 2 others, Alsadeq, A. & Jumaa, H., 2022, In: Frontiers in Immunology. 13, 19 p., 842340.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2021
  17. Published

    ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

    Brandao, R., Kwa, M. Q., Yarden, Y. & Brakebusch, Cord Herbert, 2021, In: FEBS Open Bio. 11, 6, p. 1579-1592 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells

    Xu, L., Zu, T., Li, T., Li, M., Mi, J., Bai, F., Liu, G., Wen, J., Li, H., Brakebusch, Cord Herbert, Wang, X. & Wu, X., 2021, In: PLOS Genetics. 17, 2, p. 1-25 e1009283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Analyzing skin tumor development in mice by the DMBA/TPA model

    Li, H. & Brakebusch, Cord Herbert, 2021, Carcinogen-driven mouse models of oncogenesis. Galluzzi, L. & Buqué, A. (eds.). Elsevier, Vol. 163. p. 113-121 9 p. (Methods in Cell Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  20. Published

    CRISPR Genome Editing: How to Make a Fantastic Method Even Better

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-2 408.

    Research output: Contribution to journal › Editorial › Research › peer-review

  21. Published

    MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model

    Kwa, M. Q., Brandao, R., Phung, T. H., Ge, J., Scieri, G. & Brakebusch, Cord Herbert, 2021, In: Cells. 10, 4, 942.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity

    Bock, F., Elias, B. C., Dong, X., Parekh, D. V., Mernaugh, G., Viquez, O. M., Hassan, A., Amara, V. R., Liu, J., Brown, K. L., Terker, A. S., Chiusa, M., Gewin, L. S., Fogo, A. B., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2021, In: Journal of Cell Biology. 220, 11, 28 p., e202103080.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Rho GTPase Signaling in Health and Disease: A Complex Signaling Network

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-3 401.

    Research output: Contribution to journal › Editorial › Research › peer-review

  24. Published

    RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury

    Stern, S., Hilton, B. J., Burnside, E. R., Dupraz, S., Handley, E. E., Gonyer, J. M., Brakebusch, Cord Herbert & Bradke, F., 2021, In: Neuron. 109, 21, p. 3436-3455 30 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

    Heib, T., Hermanns, H. M., Manukjan, G., Englert, M., Kusch, C., Becker, I. C., Gerber, A., Wackerbarth, L. M., Burkard, P., Dandekar, T., Balkenhol, J., Jahn, D., Beck, S., Meub, M., Dütting, S., Stigloher, C., Sauer, M., Cherpokova, D., Schulze, H., Brakebusch, C. & 3 others, Nieswandt, B., Nagy, Z. & Pleines, I., 2021, In: Cell Reports. 35, 6, p. 109102 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2020
  27. Published

    Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?

    Bischoff, N., Wimberger, S., Maresca, M. & Brakebusch, Cord Herbert, 2020, In: Cells. 9, 5

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction

    Gilles, G., McCulloch, A. D., Brakebusch, Cord Herbert & Herum, K. M., 2020, In: PLoS ONE. 15, 10, p. 1-13 e0241390.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

    Socodato, R., Portugal, C. C., Canedo, T., Rodrigues, A., Almeida, T. O., Henriques, J. F., Vaz, S. H., Magalhães, J., Silva, C. M., Baptista, F. I., Alves, R. L., Coelho-Santos, V., Silva, A. P., Paes-de-Carvalho, R., Magalhães, A., Brakebusch, Cord Herbert, Sebastião, A. M., Summavielle, T., Ambrósio, A. F. & Relvas, J. B., 2020, In: Cell Reports. 31, 12, p. 1-29 107796.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    PATHBIO: an international training program for precision mouse phenotyping

    Ruberte, J., Schofield, P. N., Brakebusch, Cord Herbert, Vogel, P., Herault, Y., Gracia, G., McKerlie, C., Hrabĕ de Angelis, M., Hagn, M. & Sundberg, J. P., 2020, In: Mammalian Genome. 31, p. 49-53

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

    Herum, K. M., Romaine, A., Wang, A., Melleby, A. O., Strand, M. E., Pacheco, J., Braathen, B., Dunér, P., Tønnessen, T., Lunde, I. G., Sjaastad, I., Brakebusch, Cord Herbert, McCulloch, A. D., Gomez, M. F., Carlson, C. R. & Christensen, G., 2020, In: Journal of the American Heart Association. 9, 3, 31 p., e013518.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway

    Zu, T., Wen, J., Xu, L., Li, H., Mi, J., Brakebusch, Cord Herbert, Fisher, D. E. & Wu, X., 2020, In: Frontiers in Oncology. 10, 15 p., 624.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2019
  34. Published

    Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

    Kage, F., Steffen, A., Ellinger, A., Ranftler, C., Gehre, C., Brakebusch, Cord Herbert, Pavelka, M., Stradal, T. & Rottner, K., 26 Nov 2019, In: Scientific Reports. 9, 1, p. 18008 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  35. Published

    RhoA Controls Axon Extension Independent of Specification in the Developing Brain

    Dupraz, S., Hilton, B. J., Husch, A., Santos, T. E., Coles, C. H., Stern, S., Brakebusch, Cord Herbert & Bradke, F., 18 Nov 2019, In: Current biology : CB. 29, 22, p. 3874-3886 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice

    López-Posadas, R., Fastancz, P., Martínez-Sánchez, L. D. C., Panteleev-Ivlev, J., Thonn, V., Kisseleva, T., Becker, L. S., Schulz-Kuhnt, A., Zundler, S., Wirtz, S., Atreya, R., Carlé, B., Friedrich, O., Schürmann, S., Waldner, M. J., Neufert, C., Brakebusch, Cord Herbert, Bergö, M. O., Neurath, M. F. & Atreya, I., Nov 2019, In: Gastroenterology. 157, 5, p. 1293-1309 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

    Akula, M. K., Ibrahim, M. X., Ivarsson, E. G., Khan, O. M., Kumar, I. T., Erlandsson, M., Karlsson, C., Xu, X., Brisslert, M., Brakebusch, Cord Herbert, Wang, D., Bokarewa, M., Sayin, V. I. & Bergo, M. O., 4 Sep 2019, In: Nature Communications. 10, 1, p. 1-13 13 p., 3975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Senescence regulation by nuclear N-WASP: a role in cancer?

    Li, H. & Brakebusch, Cord Herbert, Jul 2019, In: Oncoscience. 6, 7-8, p. 354-356 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Negative regulation of p53-induced senescence by N-WASP is crucial for DMBA/TPA-induced skin tumor formation

    Li, H., Petersen, S., Garcia Mariscal, A. & Brakebusch, Cord Herbert, 1 May 2019, In: Cancer Research. 79, 9, p. 2167-2181 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Adgrf5 contributes to patterning of the endothelial deep layer in retina

    Niaudet, C., Petkova, M., Jung, B., Lu, S., Laviña, B., Offermanns, S., Brakebusch, Cord Herbert & Betsholtz, C., 2019, In: Angiogenesis. 22, 4, p. 491-505 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A human antithrombin isoform dampens inflammatory responses and protects from organ damage during bacterial infection

    Papareddy, P., Rossnagel, M., Doreen Hollwedel, F., Kilic, G., Veerla, S., Naudin, C., Smeds, E., Westman, J., Martinez-Martinez, I., Egesten, A., de la Morena-Barrio, M. E., Corral, J., Linder, A., Artoni, A., Abbattista, M., Novembrino, C., Brakebusch, Cord Herbert, Martinelli, I., Kasetty, G. & Herwald, H., 2019, In: Nature Microbiology. 4, 12, p. 2442-2455 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    CDC42 Deletion Elicits Cerebral Vascular Malformations via Increased MEKK3-Dependent KLF4 Expression

    Castro, M., Laviña, B., Ando, K., Álvarez-Aznar, A., Abu Taha, A., Brakebusch, Cord Herbert, Dejana, E., Betsholtz, C. & Gaengel, K. B., 2019, In: Circulation Research. 124, 8, p. 1240-1252 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Cancer-associated fibroblasts: how do they contribute to metastasis?

    Kwa, M. Q., Herum, K. M. & Brakebusch, Cord Herbert, 2019, In: Clinical and Experimental Metastasis. 36, 2, p. 71-86

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    Rho GTPases in cancer: friend or foe?

    Svensmark, J. H. & Brakebusch, Cord Herbert, 2019, In: Oncogene. 38, p. 7448-7456

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones

    Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.

    Research output: Contribution to journal › Conference article › Research › peer-review

  46. Published

    The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells

    Cavaco, A. C. M., Rezaei, M., Caliandro, M. F., Lima, A. M., Stehling, M., Dhayat, S. A., Haier, J., Brakebusch, Cord Herbert & Eble, J. A., 2019, In: Cancers. 11, 1, p. 1-20 20 p., 14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The small GTPase RhoA regulates the onset of myelination and myelin production during PNS development: [Meeting Abstract}

    Seixas, A., Morais, M., Pereira, J. A., Krause, S., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2019, In: Glia. 67, S1, p. E473-E474 T12-052B.

    Research output: Contribution to journal › Conference abstract in journal › Research

  48. 2018
  49. Published

    Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

    Laviña, B., Castro, M., Niaudet, C., Cruys, B., Álvarez-Aznar, A., Carmeliet, P., Bentley, K., Brakebusch, Cord Herbert, Betsholtz, C. & Gaengel, K., 2 Jul 2018, In: Development (Cambridge, England). 145, 13, 20 p., dev161182.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB

    García-Mariscal, A., Li, H., Pedersen, E., Peyrollier, K., Ryan, K. M., Stanley, A., Quondamatteo, F. & Brakebusch, Cord Herbert, 15 Feb 2018, In: Oncogene. 37, 7, p. 847-860 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation

    Li, H., Yao, Q., Mariscal, A. G., Wu, X., Hülse, J., Pedersen, E., Helin, K., Waisman, A., Vinkel, C., Thomsen, Simon Francis, Avgustinova, A., Benitah, S. A., Lovato, P., Norsgaard, H., Mortensen, M. S., Veng, L., Rozell, B. & Brakebusch, Cord Herbert, 2018, In: Nature Communications. 9, 1, p. 1-18 18 p., 1420.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke

    Karabiyik, C., Fernandes, R., Figueiredo, F. R., Socodato, R., Brakebusch, Cord Herbert, Lambertsen, K. L., Relvas, J. B. & Santos, S. D., 2018, In: Brain Pathology. 28, 4, p. 569-580 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    RhoA Controls Retinoid Signaling by ROCK Dependent Regulation of Retinol Metabolism

    García-Mariscal, A., Peyrollier, K., Basse, A., Pedersen, E. D. K., Rühl, R., van Hengel, J. & Brakebusch, Cord Herbert, 2018, In: Small GTPases. 9, 5, p. 433–444

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

    Manresa-Arraut, A., Johansen, F. F., Brakebusch, Cord Herbert, Issazadeh-Navikas, Shohreh & Hasseldam, Henrik, 2018, In: Frontiers in Immunology. 9, p. 1-14 14 p., 1235.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells

    Ge, J., Burnier, L., Adamopoulou, M., Kwa, M. Q., Schaks, M., Rottner, K. & Brakebusch, Cord Herbert, 2018, In: The Journal of Biological Chemistry. 293, 24, p. 9358-9369 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2017
  58. Published

    FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

    Kage, F., Steffen, A., Ellinger, A., Ranftler, C., Gehre, C., Brakebusch, Cord Herbert, Pavelka, M., Stradal, T. & Rottner, K., 1 Dec 2017, In: Scientific Reports. 7, 1, 17 p., 9791.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

    Dütting, S., Gaits-Iacovoni, F., Stegner, D., Popp, M., Antkowiak, A., Van Eeuwijk, J. M. M., Nurden, P., Stritt, S., Heib, T., Aurbach, K., Angay, O., Cherpokova, D., Heinz, N., Baig, A. A., Gorelashvili, M. G., Gerner, F., Heinze, K. G., Ware, J., Krohne, G., Ruggeri, Z. M. & 6 others, Nurden, A. T., Schulze, H., Modlich, U., Pleines, I., Brakebusch, Cord Herbert & Nieswandt, B., 15 Jun 2017, In: Nature Communications. 8, 13 p., 15838.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    FMNL formins boost lamellipodial force generation

    Kage, F., Winterhoff, M., Dimchev, V., Mueller, J., Thalheim, T., Freise, A., Brühmann, S., Kollasser, J., Block, J., Dimchev, G. A., Geyer, M., Schnittler, H., Brakebusch, Cord Herbert, Stradal, T. E. B., Carlier, M., Sixt, M., Käs, J., Faix, J. & Rottner, K., 22 Mar 2017, In: Nature Communications. 8, 16 p., 14832.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin

    Woodham, E. F., Paul, N. R., Tyrrell, B., Spence, H. J., Swaminathan, K., Scribner, M. R., Giampazolias, E., Hedley, A., Clark, W., Kage, F., Marston, D. J., Hahn, K. M., Tait, S. W. G., Larue, L., Brakebusch, Cord Herbert, Insall, R. H. & Machesky, L. M., 6 Mar 2017, In: Current biology : CB. 27, 5, p. 624-637 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

    Wahlestedt, M., Erlandsson, E., Kristiansen, T., Lu, R., Brakebusch, Cord Herbert, Weissman, I. L., Yuan, J., Martin Gonzalez, Javier & Bryder, D., 22 Feb 2017, In: Nature Communications. 8, 8 p., 14533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Cytoskeletal stability in the auditory organ in vivo: RhoA is dispensable for wound healing but essential for hair cell development

    Anttonen, T., Belevich, I., Laos, M., Herranen, A., Jokitalo, E., Brakebusch, Cord Herbert & Pirvola, U., 2017, In: eNeuro. 4, 5, 17 p., e0149-17.2017.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. 2016
  65. Published

    Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

    Martin Gonzalez, Javier, Morgani, S. M., Bone, Robert Alexander, Bonderup, K., Abelechian, Sahar, Brakebusch, Cord Herbert & Brickman, Joshua Mark, 9 Aug 2016, In: Stem Cell Reports. 7, 2, p. 177-91 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Changes in dermal matrix in the absence of Rac1 in keratinocytes

    Stanley, A., Pedersen, E. D. K., Brakebusch, Cord Herbert & Quondamatteo, F., May 2016, In: Journal of Anatomy. 228, 5, p. 826-37 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice

    Choudhari, R., Minero, V. G., Menotti, M., Pulito, R., Brakebusch, Cord Herbert, Compagno, M., Voena, C., Ambrogio, C. & Chiarle, R., 10 Mar 2016, In: Blood. 127, 10, p. 1297-306 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation

    López-Posadas, R., Becker, C., Günther, C., Tenzer, S., Amann, K., Billmeier, U., Atreya, R., Fiorino, G., Vetrano, S., Danese, S., Ekici, A. B., Wirtz, S., Thonn, V., Watson, A. J. M., Brakebusch, Cord Herbert, Bergö, M., Neurath, M. F. & Atreya, I., Feb 2016, In: The Journal of Clinical Investigation. 126, 2, p. 611-26 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. 2015
  70. Published

    Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development

    Elias, B. C., Das, A., Parekh, D. V., Mernaugh, G., Adams, R., Yang, Z., Brakebusch, Cord Herbert, Pozzi, A., Marciano, D. K., Carroll, T. J. & Zent, R., 1 Dec 2015, In: Journal of Cell Science. 128, 23, p. 4293-305 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells

    Schulz, A. M., Stutte, S., Hogl, S., Luckashenak, N., Dudziak, D., Leroy, C., Forné, I., Imhof, A., Müller, S. A., Brakebusch, Cord Herbert, Lichtenthaler, S. F. & Brocker, T., 9 Nov 2015, In: Journal of Cell Biology. 211, 3, p. 553-67 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Control of Homeostasis and Dendritic Cell Survival by the GTPase RhoA

    Li, S., Dislich, B., Brakebusch, Cord Herbert, Lichtenthaler, S. F. & Brocker, T., 1 Nov 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 9, p. 4244-56 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Cofilin phosphorylation is elevated after F-actin disassembly induced by Rac1 depletion

    Liu, L., Li, J., Zhang, L., Zhang, F., Zhang, R., Chen, X., Brakebusch, Cord Herbert, Wang, Z. & Liu, X., 27 Oct 2015, In: BioFactors (Oxford, England). 41, 5, p. 352-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets

    Dütting, S., Heidenreich, J., Cherpokova, D., Amin, E., Zhang, S., Ahmadian, M. R., Brakebusch, Cord Herbert & Nieswandt, B., May 2015, In: Journal of Thrombosis and Haemostasis. 13, 5, p. 827-38 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair

    Xia, J., Swiercz, J. M., Bañón-Rodríguez, I., Matković, I., Federico, G., Sun, T., Franz, T., Brakebusch, Cord Herbert, Kumanogoh, A., Friedel, R. H., Martín-Belmonte, F., Gröne, H., Offermanns, S. & Worzfeld, T., May 2015, In: Developmental Cell. 33, 3, p. 299-313 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    INFRAFRONTIER-providing mutant mouse resources as research tools for the international scientific community

    Meehan, T. F., Chen, C. K., Koscielny, G., Relac, M., Wilkinson, P., Flicek, P., Parkinson, H., Bottomley, J., Ramirez-Solis, R., Smedley, D., Castro, A., Fessele, S., Steinkamp, R., Hagn, M., Raess, M., De Angelis, M. H., Ball, S., Blake, A., Fray, M., Kenyon, J. & 23 others, Mallon, A. M., Brown, S., Massimi, M., Matteoni, R., Tocchini-Valentini, G., Herault, Y., Kollias, G., Ulfhake, B., Demengeot, J., Fremond, C., Bosch, F., Montoliu, L., Soininen, R., Schughart, K., Brakebusch, Cord Herbert, Sedlacek, R., Rülicke, T., McKerlie, C., Malissen, B., Iraqi, F., Jonkers, J., Russig, H. & Huylebroeck, D., 28 Jan 2015, In: Nucleic Acids Research. 43, D1, p. D1171-D1175

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity

    Burbage, M., Keppler, S. J., Gasparrini, F., Martínez-Martín, N., Gaya, M., Feest, C., Domart, M., Brakebusch, Cord Herbert, Collinson, L., Bruckbauer, A. & Batista, F. D., 2015, In: The Journal of Experimental Medicine. 212, 1, p. 53-72

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. 2014
  79. Published

    Mouse macrophages completely lacking Rho (RhoA, RhoB and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and increased motility

    Koenigs, V., Jennings, R., Vogl, T., Horsthemke, M., Bachg, A. C., Xu, Y., Grobe, K., Brakebusch, Cord Herbert, Schwab, A., Baehler, M., Knaus, U. G. & Hanley, P. J., 31 Oct 2014, In: The Journal of Biological Chemistry. 289, 44, p. 30772-30784 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    How to Bury the Dead: Elimination of Apoptotic Hair Cells from the Hearing Organ of the Mouse

    Anttonen, T., Belevich, I., Kirjavainen, A., Laos, M., Brakebusch, Cord Herbert, Jokitalo, E. & Pirvola, U., 30 Jul 2014, In: J A R O. 15, 6, p. 975-992 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Rac1-dependent recruitment of PAK2 to G 2 phase centrosomes and their roles in the regulation of mitotic entry

    May, M., Schelle, I., Brakebusch, Cord Herbert, Rottner, K. & Genth, H., 19 May 2014, In: Cell Cycle. 13, 14, p. 2211-21 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    NADPH oxidase complex-derived reactive oxygen species, the actin cytoskeleton, and rho GTPases in cell migration

    Stanley, A., Thompson, K., Hynes, A., Brakebusch, Cord Herbert & Quondamatteo, F., 1 May 2014, In: Antioxidants & Redox Signaling. 20, 13, p. 2026-42 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness

    Jennings, R. T., Strengert, M., Hayes, P., El-Benna, J., Brakebusch, Cord Herbert, Kubica, M. & Knaus, U. G., 29 Apr 2014, In: Blood. 123, 23, p. 3635-45 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    The small GTPase Rac1 is required for smooth muscle contraction

    Rahman, A., Davis, B., Lövdahl, C., Hanumaiah, V. T., Feil, R., Brakebusch, Cord Herbert & Arner, A., 1 Mar 2014, In: The Journal of Physiology. 592, 5, p. 915-26 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Rho GTPases and cancer

    Li, H., Peyrollier, K., Kilic, G. & Brakebusch, Cord Herbert, Mar 2014, In: BioFactors (Oxford, England). 40, 2, p. 226-35 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  86. 2013
  87. Published

    Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes

    Wang, Z., Jiang, Z., Zhang, Q., Hu, M., Huang, L., Ou, X., Guo, L., Ouyang, Y., Hou, Y., Brakebusch, Cord Herbert, Schatten, H. & Sun, Q., Dec 2013, In: Molecular Biology of the Cell. 24, 24, p. 3832-41 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

    Pleines, I., Dütting, S., Cherpokova, D., Eckly, A., Meyer, I., Morowski, M., Krohne, G., Schulze, H., Gachet, C., Debili, N., Brakebusch, Cord Herbert & Nieswandt, B., 31 Oct 2013, In: Blood. 122, 18, p. 3178-87 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

    Steffen, A., Ladwein, M., Dimchev, G. A., Hein, A., Schwenkmezger, L., Arens, S., Ladwein, K. I., Margit Holleboom, J., Schur, F., Victor Small, J., Schwarz, J., Gerhard, R., Faix, J., Stradal, T. E. B., Brakebusch, Cord Herbert & Rottner, K., 15 Oct 2013, In: Journal of Cell Science. 126, Pt 20, p. 4572-88 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1

    Huelsenbeck, S. C., Roggenkamp, D., May, M., Huelsenbeck, J., Brakebusch, Cord Herbert, Rottner, K., Ladwein, M., Just, I., Fritz, G., Schmidt, G. & Genth, H., Aug 2013, In: International Journal of Biochemistry & Cell Biology. 45, 8, p. 1767-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Neuronal Rac1 is required for learning-evoked neurogenesis

    Haditsch, U., Anderson, M. P., Freewoman, J., Cord, B., Babu, H., Brakebusch, Cord Herbert & Palmer, T. D., 24 Jul 2013, In: Journal of Neuroscience. 33, 30, p. 12229-41 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Cdc42 promotes host defenses against fatal infection

    Lee, K., Boyd, K. L., Parekh, D. V., Kehl-Fie, T. E., Baldwin, H. S., Brakebusch, Cord Herbert, Skaar, E. P., Boothby, M. & Zent, R., 20 May 2013, In: Infection and Immunity. 81, 8, p. 2714-2723 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury

    Blattner, S. M., Hodgin, J. B., Nishio, M., Wylie, S. A., Saha, J., Soofi, A. A., Vining, C., Randolph, A., Herbach, N., Wanke, R., Atkins, K. B., Gyung Kang, H., Henger, A., Brakebusch, Cord Herbert, Holzman, L. B. & Kretzler, M., 15 May 2013, In: Kidney International.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    p21-activated Kinase1(PAK1) can promote ERK activation in a kinase independent manner

    Wang, Z., Fu, M., Wang, L., Liu, J., Li, Y., Brakebusch, Cord Herbert & Mei, Q., 7 May 2013, In: Journal of Biological Chemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Stage-specific functions of the small Rho GTPases Cdc42 and Rac1 for adult hippocampal neurogenesis

    Vadodaria, K. C., Brakebusch, Cord Herbert, Suter, U. & Jessberger, S., 16 Jan 2013, In: Journal of Neuroscience. 33, 3, p. 1179-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo

    Luckashenak, N., Wähe, A., Breit, K., Brakebusch, Cord Herbert & Brocker, T., 1 Jan 2013, In: Journal of Immunology. 190, 1, p. 27-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. 2012
  98. Published

    RAC1 in keratinocytes regulates crosstalk to immune cells by Arp2/3-dependent control of STAT1

    Pedersen, E. D. K., Wang, Z., Stanley, A., Peyrollier, K., Rösner, L. M., Werfel, T., Quondamatteo, F. & Brakebusch, Cord Herbert, 15 Nov 2012, In: Journal of Cell Science. 125, Pt 22, p. 5379-90 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Rho GTPases and Nox dependent ROS production in skin. Is there a connection?

    Stanley, A., Hynes, A., Brakebusch, Cord Herbert & Quondamatteo, F., Nov 2012, In: Histology and Histopathology. 27, 11, p. 1395-406 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  100. Published

    Opposing roles for RhoH GTPase during T-cell migration and activation

    Baker, C. M., Comrie, W. A., Hyun, Y., Chung, H., Fedorchuk, C. A., Lim, K., Brakebusch, Cord Herbert, McGrath, J. L., Waugh, R. E., Meier-Schellersheim, M. & Kim, M., 26 Jun 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. 10474-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    FMNL2 drives actin-based protrusion and migration downstream of Cdc42

    Block, J., Breitsprecher, D., Kühn, S., Winterhoff, M., Kage, F., Geffers, R., Duwe, P., Rohn, J. L., Baum, B., Brakebusch, Cord Herbert, Geyer, M., Stradal, T. E. B., Faix, J. & Rottner, K., 5 Jun 2012, In: Current Biology. 22, 11, p. 1005-12 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Rho GTPase function in development: How in vivo models change our view

    Pedersen, E. & Brakebusch, Cord Herbert, 29 May 2012, In: Experimental Cell Research. 318, 14, p. 1779-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Podocyte-specific loss of cdc42 leads to congenital nephropathy

    Scott, R. P., Hawley, S. P., Ruston, J., Du, J., Brakebusch, Cord Herbert, Jones, N. & Pawson, T., 19 Apr 2012, In: Journal of the American Society of Nephrology. 23, 7, p. 1149-54 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    A radial glia-specific role of RhoA in double cortex formation

    Cappello, S., Böhringer, C. R. J., Bergami, M., Conzelmann, K., Ghanem, A., Tomassy, G. S., Arlotta, P., Mainardi, M., Allegra, M., Caleo, M., van Hengel, J., Brakebusch, Cord Herbert & Götz, M., 8 Mar 2012, In: Neuron. 73, 5, p. 911-24 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice

    Sakamori, R., Das, S., Yu, S., Feng, S., Stypulkowski, E., Guan, Y., Douard, V., Tang, W., Ferraris, R. P., Harada, A., Brakebusch, Cord Herbert, Guo, W. & Gao, N., 1 Mar 2012, In: Journal of Clinical Investigation. 122, 3, p. 1052-65 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    A function for Rac1 in the terminal differentiation and pigmentation of hair

    Behrendt, K., Klatte, J., Pofahl, R., Bloch, W., Smyth, N., Tscharntke, M., Krieg, T., Paus, R., Niessen, C., Niemann, C., Brakebusch, Cord Herbert & Haase, I., 24 Jan 2012, In: Journal of Cell Science. 125, Pt 4, p. 896-905 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  107. Published

    Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood

    Anttonen, T., Kirjavainen, A., Belevich, I., Laos, M., Richardson, W. D., Jokitalo, E., Brakebusch, Cord Herbert & Pirvola, U., 2012, In: Scientific Reports. 2, p. 978

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues

    Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chunaram, 2012, In: Molecular & Cellular Proteomics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. 2011
  110. Published

    Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis

    Pleines, I., Hagedorn, I., Gupta, S., May, F., Chakarova, L., van Hengel, J., Offermanns, S., Krohne, G., Kleinschnitz, C., Brakebusch, Cord Herbert & Nieswandt, B., 1 Nov 2011, In: Blood. 119, 4, p. 1054-63 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  111. Published

    Genetic deletion of cdc42 reveals a crucial role for astrocyte recruitment to the injury site in vitro and in vivo

    Robel, S., Bardehle, S., Lepier, A., Brakebusch, Cord Herbert & Götz, M., 31 Aug 2011, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 31, 35, p. 12471-82 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  112. Published

    Cdc42 Controls Vascular Network Assembly Through Protein Kinase C{iota} During Embryonic Vasculogenesis

    Qi, Y., Liu, J., Wu, X., Brakebusch, Cord Herbert, Leitges, M., Han, Y., Corbett, S. A., Lowry, S. F., Graham, A. M. & Li, S., 1 Aug 2011, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 8, p. 1861-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  113. Published

    The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool

    Herzog, D., Loetscher, P., van Hengel, J., Knüsel, S., Brakebusch, Cord Herbert, Taylor, V., Suter, U. & Relvas, J. B., 30 Mar 2011, In: Journal of Neuroscience. 31, 13, p. 5120-30 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  114. Published

    RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

    Jackson, B., Peyrollier, K., Pedersen, E., Basse, A., Karlsson, R., Wang, Z., Lefever, T., Ochsenbein, A. M., Schmidt, G., Aktories, K., Stanley, A., Quondamatteo, F., Ladwein, M., Rottner, K., van Hengel, J. & Brakebusch, Cord Herbert, 1 Mar 2011, In: Molecular Biology of the Cell. 22, 5, p. 593-605 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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