Claus Desler Madsen

Claus Desler Madsen

Associate Professor


  1. 2018
  2. Published

    Initial brain aging : heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus. / Thomsen, Kirsten; Yokota, Takashi; Hasan-Olive, Md Mahdi; Sherazi, Niloofar; Fakouri, Nima Borhan; Desler, Claus; Regnell, Christine Elisabeth; Larsen, Steen; Rasmussen, Lene Juel; Dela, Flemming; Bergersen, Linda Hildegard; Lauritzen, Martin.

    In: Neurobiology of Aging, Vol. 61, 2018, p. 215-224.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms. / Jakobsen, Emil; Lange, Sofie C; Andersen, Jens Velde; Madsen, Claus Desler; Kihl, Henriette Filholm; Hohnholt, Michaela; Stridh, Malin H; Rasmussen, Lene Juel; Waagepetersen, Helle S.; Bak, Lasse Kristoffer.

    In: Biochemical Pharmacology, Vol. 155, 2018, p. 92-101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The role of mitochondrial dysfunction in the progression of Alzheimer’s disease. / Desler, Claus; Lillenes, Meryl S.; Tønjum, Tone; Rasmussen, Lene Juel.

    In: Current Medicinal Chemistry, Vol. 25, No. 40, 2018, p. 5578 - 5587.

    Research output: Contribution to journalReviewResearchpeer-review

  5. 2017
  6. Published

    Bacterial infection increases risk of carcinogenesis by targeting mitochondria. / Strickertsson, Jesper A.B.; Desler, Claus; Rasmussen, Lene Juel.

    In: Seminars in Cancer Biology, Vol. 47, 12.2017, p. 95-100.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage. / Hopkinson, Branden M; Madsen, Claus Desler; Kalisz, Mark; Vestentoft, Peter Siig; Juel Rasmussen, Lene; Bisgaard, Hanne Cathrine.

    In: Oxidative Medicine and Cellular Longevity, Vol. 2017, 5080128, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis. / Fakouri, Nima Borhan; Durhuus, Jon Ambaek; Regnell, Christine Elisabeth; Angleys, Maria; Desler, Claus; Hasan-Olive, Mahdi; Martin-Pardillos, Ana; Tsaalbi-Shtylik, Anastasia; Thomsen, Kirsten; Lauritzen, Martin; Bohr, Vilhelm A.; de Wind, Niels; Bergersen, Linda Hildegard; Rasmussen, Lene Juel.

    In: Scientific Reports, Vol. 7, 12480, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2016
  10. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression. / Syed, Salahuddin; Madsen, Claus Desler; Rasmussen, Lene J.; Schmidt, Kristina H.

    In: P L o S Genetics, Vol. 12, No. 12, e1006451, 12.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation. / Toft-Kehler, Anne Katrine; Gurubaran, Iswariyaraja Sridevi; Madsen, Claus Desler; Rasmussen, Lene J.; Skytt, Dorte Marie; Kolko, Miriam.

    In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 6, 05.2016, p. 2721-2728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2015
  13. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline. / Madsen, Claus Desler; Frederiksen, Jane H; Olsen, Maria Nathalie Angleys; Maynard, Scott; Keijzers, Guido; Fagerlund, Birgitte; Mortensen, Erik Lykke; Osler, Merete; Lauritzen, Martin; Bohr, Vilhelm A; Rasmussen, Lene Juel.

    In: Mitochondrion, Vol. 25, 11.2015, p. 34-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients. / Maynard, Scott; Hejl, Anne-Mette; Dinh, Tran Thuan Son; Keijzers, Guido; Hansen, Åse M; Madsen, Claus Desler; Moreno-Villanueva, Maria; Bürkle, Alexander; Rasmussen, Lene J; Waldemar, Gunhild; Bohr, Vilhelm A.

    In: Aging, Vol. 7, No. 10, 10.2015, p. 793-815.

    Research output: Contribution to journalJournal articleResearchpeer-review

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