Christina Christoffersen

Christina Christoffersen

Associate Professor


  1. 2024
  2. E-pub ahead of print

    Blood biomarkers improve the prediction of prevalent and incident severe chronic kidney disease

    Nusinovici, S., Li, H., Chong, C., Yu, M., Sørensen, I. M. H., Bisgaard, Line, Christoffersen, Christina, Bro, S., Liu, S., Liu, J. J., Chi, L. S., Wong, T. Y., Tan, G. S. W., Cheng, C. Y. & Sabanayagam, C., 2024, (E-pub ahead of print) In: Journal of Nephrology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Discovery of plasma proteins associated with ventricular fibrillation during first ST-elevation myocardial infarction via proteomics

    Stampe, N. K., Ottenheijm, Maud Eline, Drici, L., Albrechtsen, Nicolai Jacob Wewer, Nielsen, A. B., Christoffersen, Christina, Warming, P. E., Engstrøm, Thomas, Winkel, B. G., Jabbari, R., Tfelt-Hansen, Jacob & Glinge, C., 2024, In: European Heart Journal: Acute Cardiovascular Care. 13, 3, p. 264–272

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Kidney derived apolipoprotein M and its role in acute kidney injury

    Bisgaard, Line, Christensen, P. M., Oh, J., Torta, F., Füchtbauer, E. M., Nielsen, L. B. & Christoffersen, Christina, 2024, In: Frontiers in Pharmacology. 15, 1328259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2023
  6. Published

    Super-Resolution Ultrasound Imaging of Renal Vascular Alterations in Zucker Diabetic Fatty Rats during the Development of Diabetic Kidney Disease

    Søgaard, S. B., Andersen, S. B., Taghavi, I., Schou, M., Christoffersen, Christina, Jacobsen, Jens Christian Brings, Kjer, H. M., Gundlach, C., McDermott, Amy, Jensen, J. A., Nielsen, Michael Bachmann & Sorensen, Charlotte Mehlin, 12 Oct 2023, In: Diagnostics. 13, 20, 3197.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury

    Guo, Z., Valenzuela Ripoll, C., Picataggi, A., Rawnsley, D. R., Ozcan, M., Chirinos, J. A., Chendamarai, E., Girardi, A., Riehl, T., Evie, H., Diab, A., Kovacs, A., Hyrc, K., Ma, X., Asnani, A., Shewale, S. V., Scherrer-Crosbie, M., Cowart, L. A., Parks, J. S., Zhao, L. & 14 others, Gordon, D., Ramirez-Valle, F., Margulies, K. B., Cappola, T. P., Desai, A. A., Pedersen, L. N., Bergom, C., Stitziel, N. O., Rettig, M. P., DiPersio, J. F., Hajny, Stefan, Christoffersen, Christina, Diwan, A. & Javaheri, A., 2023, In: JACC: Basic to Translational Science. 8, 3, p. 340-355

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Coronary and extra-coronary artery calcium scores as predictors of cardiovascular events and mortality in chronic kidney disease stages 1-5: a prospective cohort study

    Sorensen, I. M. H., Bjergfelt, S. S., Hjortkjær, H. O., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Christoffersen, Christina & Bro, S., 2023, In: Nephrology Dialysis Transplantation. 38, 5, p. 1227–1239 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Gestational Hypertension and High-Density Lipoprotein Function: An Explorative Study in Overweight/Obese Women of the DALI Cohort

    Stadler, J. T., van Poppel, M. N. M., Christoffersen, Christina, Hill, D., Wadsack, C., Simmons, D., Desoye, G., Marsche, G. & DALI Core Investigator Grp, 2023, In: Antioxidants. 12, 1, 13 p., 68.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Identification of Glomerular and Plasma Apolipoprotein M as Novel Biomarkers in Glomerular Disease

    Drexler, Y., Molina, J., Elfassy, T., Ma, R., Christoffersen, Christina, Kurano, M., Yatomi, Y., Mariani, L. H., Contreras, G., Merscher, S. & Fornoni, A., 2023, In: Kidney International Reports. 8, 4, p. 884-897

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Plasma activin A rises with declining kidney function and is independently associated with mortality in patients with chronic kidney disease

    Nordholm, A., Sørensen, I. M. H., Bjergfelt, S. S., Fuchs, A., Kofoed, Klaus Fuglsang, Landler, N. E., Biering-Sørensen, Tor, Carlson, N., Feldt-Rasmussen, Bo, Christoffersen, Christina & Bro, S., 2023, In: Clinical Kidney Journal. 16, 12, p. 2712-2720 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2022
  13. Published

    Super-Resolution Ultrasound Imaging Provides Quantification of the Renal Cortical and Medullary Vasculature in Obese Zucker Rats: A Pilot Study

    Søgaard, S. B., Andersen, S. B., Taghavi, I., Hoyos, C. A. V., Christoffersen, Christina, Hansen, Kristoffer Lindskov, Jensen, J. A., Nielsen, Michael Bachmann & Sorensen, Charlotte Mehlin, Jul 2022, In: Diagnostics. 12, 7, 1626.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Association between plasma apolipoprotein M and cardiac autonomic neuropathy in type 1 diabetes

    Safi, M., Borup, A., Stevns Hansen, C., Rossing, Peter, Thorsten Jensen, M. & Christoffersen, Christina, 2022, In: Diabetes Research and Clinical Practice. 189, 7 p., 109943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Association of apolipoprotein M and sphingosine-1-phosphate with brown adipose tissue after cold exposure in humans

    Borup, A., Donkin, I., Boon, M. R., Frydland, M., Martinez-Tellez, B., Loft, A., Keller, S. H., Kjær, Andreas, Kjærgaard, Jesper, Hassager, Christian, Barrès, Romain, Rensen, P. C. N. & Christoffersen, Christina, 2022, In: Scientific Reports. 12, 1, 11 p., 18753.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Associations Between Albuminuria, Estimated GFR and Cardiac Phenotype in a Cohort with Chronic Kidney Disease: The CPH-CKD ECHO Study

    Landler, N. E., Olsen, F. J., Christensen, J., Bro, S., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A., Christoffersen, Christina, Ballegaard, E. L. F., Sørensen, I. M. H., Bjergfelt, S. S., Seidelin, E., Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: Journal of Cardiac Failure. 28, 11, p. 1615-1627 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Endothelial-Specific Loss of Sphingosine-1-Phosphate Receptor 1 Increases Vascular Permeability and Exacerbates Bleomycin-induced Pulmonary Fibrosis

    Knipe, R. S., Spinney, J. J., Abe, E. A., Probst, C. K., Franklin, A., Logue, A., Giacona, F., Drummond, M., Griffith, J., Brazee, P. L., Hariri, L. P., Montesi, S. B., Black, K. E., Hla, T., Kuo, A., Cartier, A., Engelbrecht, E., Christoffersen, C., Shea, B. S., Tager, A. M. & 1 others, Medoff, B. D., 2022, In: American Journal of Respiratory Cell and Molecular Biology. 66, 1, p. 38-52 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    Left ventricular structure and function in patients with chronic kidney disease assessed by 3D echocardiography: the CPH-CKD ECHO study

    Christensen, J., Landler, N. E., Olsen, F. J., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A. L., Christoffersen, Christina, Ballegaard, E. L. F., Sørensen, I. M. H., Bjergfelt, S. S., Seidelin, E., Bro, S. & Biering-Sørensen, Tor, 2022, In: International Journal of Cardiovascular Imaging. 38, 6, p. 1233–1244 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism

    Metz, Sophia, Krarup, N. T., Bryrup, T., Støy, J., Andersson, E. A., Christoffersen, Christina, Neville, M. J., Christiansen, Malene Revsbech, Jonsson, Anna Elisabet, Witte, D. R., Kampmann, U., Nielsen, L. B., Jørgensen, Niklas Rye, Karpe, F., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 2022, In: Journal of the Endocrine Society. 6, 5, 10 p., bvac034.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The metabolic signature of cardiovascular disease and arterial calcification in patients with chronic kidney disease

    Sørensen, I. M., Bisgaard, Line, Bjergfelt, S. S., Ballegaard, E. L., Biering-Sørensen, Tor, Landler, N. E., Pedersen, T. X., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Bro, S. & Christoffersen, Christina, 2022, In: Atherosclerosis. 350, p. 109-118 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2021
  23. Published

    Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein

    Velagapudi, S., Rohrer, L., Poti, F., Feuerborn, R., Perisa, D., Wang, D., Panteloglou, G., Potapenko, A., Yalcinkaya, M., Hulsmeier, A. J., Hesse, B., Lukasz, A., Liu, M., Parks, J. S., Christoffersen, Christina, Stoffel, M., Simoni, M., Nofer, J. & von Eckardstein, A., 2021, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 41, 10, p. E468-E479 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Apolipoprotein M and its impact on endothelial dysfunction and inflammation in the cardiovascular system

    Yao Mattisson, I. & Christoffersen, Christina, 2021, In: Atherosclerosis. 334, p. 76-84

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Apolipoprotein M-A Marker or an Active Player in Type II Diabetes?

    Christoffersen, Christina, 2021, In: Frontiers in Endocrinology. 12, 10 p., 665393.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Carotid plaque thickness is increased in chronic kidney disease and associated with carotid and coronary calcification

    Bjergfelt, S. S., Sørensen, I. M. H., Hjortkjær, H., Landler, N., Ballegaard, E. L. F., Biering-Sørensen, Tor, Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Sillesen, Henrik, Christoffersen, Christina & Bro, S., 2021, In: PLoS ONE. 16, 16 p., e0260417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Increased plasma apoM levels impair triglyceride turnover in mice

    Hajny, Stefan, Borup, A., Elsoe, S. & Christoffersen, Christina, 2021, In: B B A - Molecular and Cell Biology of Lipids. 1866, 9, 9 p., 158969.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    KIDNEY DERIVED APOM AND ITS ROLE IN ACUTE KIDNEY INJURY

    Bisgaard, Line, Christensen, P. M., Fuchtbauer, E., Nielsen, L. B. & Christoffersen, Christina, 2021, In: Nephrology Dialysis Transplantation. 36, Suppl. 1, p. 240-240 MO339.

    Research output: Contribution to journalConference abstract in journalResearch

  29. Published

    METABOLIC PROFILING AS A MARKER OF CARDIOVASCULAR DISEASE AND ARTERIAL CALCIFICATION IN THE COPENHAGEN CHRONIC KIDNEY DISEASE COHORT

    Soerensen, I. M. H., Bisgaard, Line, Bjergfelt, S. S., Ballegaard, E. L. F., Biering-Sørensen, Tor, Landler, N. E., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Bro, S. & Christoffersen, Christina, 2021, In: Nephrology Dialysis Transplantation. 36, Suppl. 1, 2 p., FC060.

    Research output: Contribution to journalConference abstract in journalResearch

  30. Published

    Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats

    Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael J., 2021, In: Scientific Reports. 11, 1, 18 p., 12712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Study protocol: Long-term effect of the New Nordic Renal Diet on phosphorus and lipid homeostasis in patients with chronic kidney disease, stages 3 and 4: a randomised controlled trial

    Hansen, N. M., Rix, M., Kamper, A., Feldt-Rasmussen, Bo, Christoffersen, Christina, Astrup, A. & Salomo, L., 2021, In: B M J Open. 11, 8, 7 p., e045754.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The apoM/S1P Complex - A Mediator in Kidney Biology and Disease?

    Bisgaard, Line & Christoffersen, Christina, 2021, In: Frontiers in Medicine. 8, 11 p., 754490.

    Research output: Contribution to journalReviewResearchpeer-review

  33. 2020
  34. Published

    Neonatal HDL Counteracts Placental Vascular Inflammation via S1P-S1PR1 Axis

    Gaudio, I. D., Hendrix, S., Christoffersen, Christina & Wadsack, C., 25 Jan 2020, In: International Journal of Molecular Sciences. 21, 3, 789.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair

    Ding, B. S., Yang, D., Swendeman, S. L., Christoffersen, Christina, Nielsen, L. B., Friedman, S. L., Powell, C. A., Hla, T. & Cao, Z., 2020, In: Developmental Cell. 53, 6, p. 677-690

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Apolipoprotein M and Risk of Type 2 Diabetes

    Hajny, Stefan, Christoffersen, M., Dalila, N., Nielsen, L. B., Tybjærg-Hansen, Anne & Christoffersen, Christina, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 9, p. 3046-3057

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cardiovascular prognostic value of echocardiography and N terminal pro B-type natriuretic peptide in type 1 diabetes: The Thousand and 1 Study

    Rørth, R., Jørgensen, P. G., Andersen, H. U., Christoffersen, Christina, Goetze, Jens P. , Køber, Lars Valeur, Rossing, Peter & bqn654, bqn654, 2020, In: European Journal of Endocrinology. 182, 5, p. 481-488

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature

    Del Gaudio, I., Sreckovic, I., Zardoya-Laguardia, P., Bernhart, E., Christoffersen, Christina, Frank, S., Marsche, G., Illanes, S. E. & Wadsack, C., 2020, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1865, 4, 11 p., 158632.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effect of insulin on natriuretic peptide gene expression in porcine heart

    Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure

    Chirinos, J. A., Zhao, L., Jia, Y., Frej, C., Adamo, L., Mann, D., Shewale, S. V., Millar, J. S., Rader, D. J., French, B., Brandimarto, J., Margulies, K. B., Parks, J. S., Wang, Z., Sieffert, D. A., Fang, J., Sweitzer, N., Christoffersen, C., Dahlbäck, B., Car, B. D. & 3 others, Gordon, D. A., Cappola, T. P. & Javaheri, A., 2020, In: Circulation. 141, 18, p. 1463–1476

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Regional distribution and severity of arterial calcification in patients with chronic kidney disease stages 1-5: a cross-sectional study of the Copenhagen chronic kidney disease cohort

    Sorensen, I. M. H., Saurbrey, S. A. K., Hjortkjaer, H. O., Brainin, P., Carlson, N., Ballegaard, E. L. F., Kamper, A., Christoffersen, Christina, Feldt-Rasmussen, Bo, Kofoed, Klaus Fuglsang & Bro, S., 2020, In: BMC Nephrology. 21, 1, 11 p., 534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Vascular function in adults with cyanotic congenital heart disease

    Tarp, J. B., Clausen, P., Celermajer, D., Christoffersen, Christina, Jensen, A. S., Sorensen, K., Sillesen, Henrik, Estensen, M., Nagy, E., von Holstein-Rathlou, Niels-Henrik, Engstrøm, Thomas, Feldt-Rasmussen, Bo & Søndergaard, Lars, 2020, In: IJC Heart and Vasculature. 30, 7 p., 100632.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2019
  44. Published

    Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding

    Tian, E., Wang, S., Zhang, L., Zhang, Y., Malicdan, M. C., Mao, Y., Christoffersen, Christina, Tabak, L. A., Schjoldager, Katrine Ter-Borch Gram & Ten Hagen, K. G., 10 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25196-25202

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis

    Mathiesen Janiurek, M., Soylu-Kucharz, R., Christoffersen, Christina, Kucharz, Krzysztof & Lauritzen, Martin, 25 Nov 2019, In: eLife. 8, 22 p., e49405.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Apolipoprotein M/sphingosine-1-phosphate: novel effects on lipids, inflammation and kidney biology

    Bisgaard, L. S. & Christoffersen, Christina, 2019, In: Current Opinion in Lipidology. 30, 3, p. 212-217

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Diurnal regulation of sphingolipids in blood

    Brunkhorst, R., Pfeilschifter, W., Rajkovic, N., Pfeffer, M., Fischer, C., Korf, H. W., Christoffersen, Christina, Trautmann, S., Thomas, D., Pfeilschifter, J. & Koch, A., 2019, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 3, p. 304-311

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Effect of menopause and exercise training on plasma apolipoprotein M and sphingosine-1-phosphate

    Yafasova, A., djc739, djc739, Egelund, J., Nyberg, M. P., Stallknecht, Bente Merete, Hellsten, Ylva, Nielsen, L. B. & Christoffersen, Christina, 2019, In: Journal of Applied Physiology. 126, 1, p. 214-220 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway

    Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Molecular Characterization of Microvesicular and Macrovesicular Steatosis Shows Widespread Differences in Metabolic Pathways

    Kristiansen, M., Veidal, S. S., Christoffersen, Christina, Jelsing, J. & Rigbolt, K. T. G., 2019, In: Lipids. 54, 1, p. 109-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Subclinical atherosclerosis in patients with cyanotic congenital heart disease

    Tarp, J. B., Sorgaard, M. H., Christoffersen, Christina, Jensen, A. S., Sillesen, Henrik, Celermajer, D., Eriksson, P., Estensen, M., Nagy, E., von Holstein-Rathlou, Niels-Henrik, Engstrøm, Thomas & Søndergaard, Lars, 2019, In: International Journal of Cardiology. 277, p. 97-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH

    Kristiansen, M. N. B., Veidal, S. S., Christoffersen, Christina, Feigh, M., Vrang, N., Roth, J. D., Erickson, M., Adorini, L. & Jelsing, J., 2019, In: B M C Gastroenterology. 19, 1, 11 p., 228 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2018
  54. Published

    Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]

    Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael J., 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  55. Published

    The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

    Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Apolipoprotein M in patients with chronic kidney disease

    Sørensen, I. M., Bertelsen, M., Freese, E., Lindhard, K., Ullum, H., Feldt-Rasmussen, Bo, Nielsen, L. B., Christoffersen, Christina & Bro, S., 2018, In: Atherosclerosis. 275, p. 304-311

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Functional brown adipose tissue and sympathetic activity after cold exposure in humans with type 1 narcolepsy

    Enevoldsen, L. H., Tindborg, M., Hovmand, N. L., Christoffersen, Christina, Ellingsgaard, H., Suetta, Charlotte, Stallknecht, Bente Merete, Jennum, Poul, Kjær, Andreas & Gammeltoft, S., 2018, In: Sleep. 41, 8, p. 1-9 zsy092.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

    Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T. & 1 others, Clausen, Henrik, 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. 2017
  60. Published

    ApoB and apoM - New aspects of lipoprotein biology in uremia-induced atherosclerosis

    Christoffersen, Christina, Bartels, Emil Daniel, Pedersen, A. A., Nielsen, L. B. & Pedersen, T. X., Dec 2017, In: European Journal of Pharmacology. 816, p. 154-160 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes

    Christensen, P. M., Bosteen, M. H., Hajny, Stefan, Nielsen, L. B. & Christoffersen, Christina, 8 Nov 2017, In: Scientific Reports. 7, 10 p., 14983.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Effects of apolipoprotein M in uremic atherosclerosis

    Bosteen, M. H., Madsen Svarrer, E. M., Bisgaard, Line, Martinussen, Torben, Madsen, M., Nielsen, L. B., Christoffersen, Christina & Pedersen, T. X., Oct 2017, In: Atherosclerosis. 265, p. 93-101 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation

    Hajny, Stefan & Christoffersen, Christina, 27 Jul 2017, In: International Journal of Molecular Sciences. 18, 8, 19 p., 1636.

    Research output: Contribution to journalReviewResearchpeer-review

  64. Published

    High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression

    Feuerborn, R., Becker, S., Potì, F., Nagel, P., Brodde, M., Schmidt, H., Christoffersen, Christina, Ceglarek, U., Burkhardt, R. & Nofer, J., Feb 2017, In: Atherosclerosis. 257, p. 29-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs

    Shim, J., Poulsen, C. B., Hagensen, M. K., Larsen, T., Heegaard, P. M. H., Christoffersen, Christina, Bolund, L., Schmidt, M., Liu, Y., Li, J., Li, R., Callesen, H., Bentzon, J. F. & Sørensen, C. B., 2017, In: JACC: Basic to Translational Science. 2, 5, p. 591-600 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. 2016
  67. Published

    HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver

    Ding, B., Liu, C. H., Sun, Y., Chen, Y., Swendeman, S. L., Jung, B., Chavez, D., Cao, Z., Christoffersen, Christina, Nielsen, L. B., Schwab, S. R., Rafii, S. & Hla, T., 22 Dec 2016, In: JCI insight. 1, 21, 16 p., e87058.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis

    Pedersen, A. A., Pedersen, T. X., Junker, N., Christoffersen, Christina, Bartels, Emil Daniel, Madsen, M., Nielsen, Carsten Haagen & Nielsen, L. B., Sep 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 1782-1790 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

    Khetarpal, S. A., Schjoldager, K. T., Christoffersen, C., Raghavan, A., Edmondson, A. C., Reutter, H. M., Ahmed, B., Ouazzani, R., Peloso, G. M., Vitali, C., Zhao, W., Somasundara, A. V. H., Millar, J. S., Park, Y., Fernando, G., Livanov, V., Choi, S., Noé, E., Patel, P., Ho, S. P. & 12 others, Kirchgessner, T. G., Wandall, Hans H., Hansen, Lars, Bennett, Eric Paul, Vakhrushev, Sergey, Saleheen, D., Kathiresan, S., Brown, C. D., Abou Jamra, R., LeGuern, E., Clausen, Henrik & Rader, D. J., 9 Aug 2016, In: Cell Metabolism. 24, 2, p. 234-245 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Familial hypercholesterolaemia: cholesterol efflux and coronary disease

    Versmissen, J., Vongpromek, R., Yahya, R., van der Net, J. B., van Vark-van der Zee, L., Blommesteijn-Touw, J., Wattimena, D., Rietveld, T., Pullinger, C. R., Christoffersen, Christina, Dahlbäck, B., Kane, J. P., Mulder, M. & Sijbrands, E. J. G., Jul 2016, In: European Journal of Clinical Investigation. 46, 7, p. 643-50 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1

    Christensen, P. M., Liu, C. H., Swendeman, S. L., Obinata, H., Qvortrup, Klaus, Nielsen, L. B., Hla, T., Di Lorenzo, A. & Christoffersen, Christina, Jun 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2351-2359 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43

    Morel, S., Christoffersen, Christina, Axelsen, L. N., Montecucco, F., Rochemont, V., Frias, M. A., Mach, F., James, R. W., Naus, C. C., Chanson, M., Lampe, P. D., Nielsen, Morten Schak, Nielsen, L. B. & Kwak, B. R., 13 Jan 2016, In: Cardiovascular Research. 109, p. 385-396 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. 2015
  74. Published

    Diurnal gene expression of lipolytic natriuretic peptide receptors in white adipose tissue

    Smith, J., Fahrenkrug, J., Jørgensen, H. L., Christoffersen, Christina & Goetze, J. P., Dec 2015, In: Endocrine Connections. 4, 4, p. 206-214 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA

    Bosteen, M. H., Dahlbäck, B., Nielsen, L. B. & Christoffersen, Christina, 1 Mar 2015, In: Journal of Lipid Research. 56, 3, p. 754-759 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Apolipoprotein M in lipid metabolism and cardiometabolic diseases

    Borup, A., Christensen, P. M., Nielsen, L. B. & Christoffersen, Christina, Feb 2015, In: Current Opinion in Lipidology. 26, 1, p. 48-55 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  77. Published

    Altered Metabolism of LDL in the Arterial Wall Precedes Atherosclerosis Regression

    Bartels, Emil Daniel, Christoffersen, Christina, Lindholm, M. W. & Nielsen, L. B., 2015, In: Circulation Research. 117, p. 933-942 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Diabetes with poor glycaemic control does not promote atherosclerosis in genetically modified hypercholesterolaemic minipigs

    Al-Mashhadi, R. H., Bjørklund, M. M., Mortensen, M. B., Christoffersen, Christina, Larsen, T., Falk, E. & Bentzon, J. F., 2015, In: Diabetologia. 58, 8, p. 1926-36 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. 2014
  80. Published

    Induction of atherosclerosis in mice and hamsters without germline genetic engineering

    Bjørklund, M. M., Hollensen, A. K., Hagensen, M. K., Dagnæs-Hansen, F., Christoffersen, Christina, Mikkelsen, J. G. & Bentzon, J. F., 23 May 2014, In: Circulation Research. 114, 11, p. 1684-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Apolipoprotein M: Impact on lipoprotein metabolism and vascular function

    Christoffersen, Christina, 2014, Frederiksberg: Det Sundhedsvidenskabelige Fakultet, Københavns Universitet. 118 p.

    Research output: Book/ReportDoctoral thesisResearch

  82. Published

    Effect of atrial natriuretic peptide on lipolysis in the mouse heart

    Bartels, Emil Daniel, Bisgaard, Line, Christoffersen, Christina & Nielsen, L. B., 2014, In: Cardiovascular Endocrinology. 3, 3, p. 92-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. 2013
  84. Published

    Apolipoprotein M: bridging HDL and endothelial function

    Christoffersen, Christina & Nielsen, L. B., Aug 2013, In: Current Opinion in Lipidology. 24, 4, p. 295-300 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

    Elsøe, S., Christoffersen, Christina, Luchoomun, J., Turner, S. & Nielsen, L. B., Jul 2013, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1831, 7, p. 1287-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Osteopontin deficiency dampens the pro-atherogenic effect of uraemia

    Pedersen, T. X., Madsen, M., Nielsen, N. M. J., Christoffersen, Christina, Vikeså, J., Bro, S., Hultgårdh-Nilsson, A. & Nielsen, L. B., 1 Jun 2013, In: Cardiovascular Research. 98, 3, p. 352-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    The apolipoprotein m-sphingosine-1-phosphate axis: biological relevance in lipoprotein metabolism, lipid disorders and atherosclerosis

    Arkensteijn, B. W. C., Berbée, J. F. P., Rensen, P. C. N., Nielsen, L. B. & Christoffersen, Christina, 25 Feb 2013, In: International Journal of Molecular Sciences (Online). 14, 3, p. 4419-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets

    Smith, J., Christoffersen, Christina, Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Gøtze, J. P., 2013, In: Endocrinology. 154, 5, p. 1864-1872 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant

    Al-Mashhadi, R. H., Sørensen, C. B., Kragh, P. M., Christoffersen, C., Mortensen, M. B., Tolbod, L. P., Thim, T., Du, Y., Li, J., Liu, Y., Moldt, B., Schmidt, M., Vajta, G., Larsen, T., Purup, S., Bolund, L., Nielsen, L. B., Callesen, H., Falk, E., Mikkelsen, J. G. & 1 others, Bentzon, J. F., 2013, In: Science Translational Medicine. 5, 166, 11 p., 166ra1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. 2012
  91. Published

    (18)F-FDG PET imaging of murine atherosclerosis: association with gene expression of key molecular markers

    Hag, Anne Mette Fisker, Pedersen, S. F., Christoffersen, Christina, Binderup, Tina, Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Skovgaard, D., Ripa, Rasmus Sejersten & Kjær, Andreas, 2012, In: P L o S One. 7, 11, p. e50908

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Apolipoprotein M - a new biomarker in sepsis

    Christoffersen, Christina & Nielsen, L. B., 2012, In: Critical Care (Online Edition). 16, 3, p. 126

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL

    Elsøe, S., Ahnström, J., Christoffersen, Christina, Hoofnagle, A. N., Plomgaard, Peter Stendahl, Heinecke, J. W., Binder, C. J., Björkbacka, H., Dahlbäck, B. & Nielsen, L. B., 2012, In: Atherosclerosis. 221, 1, p. 91-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

    Gordts, P. L. S. M., Bartelt, A., Nilsson, S. K., Annaert, W., Christoffersen, Christina, Nielsen, L. B., Heeren, J. & Roebroek, A. J. M., 2012, In: P L o S One. 7, 6, p. e38330

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles

    Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. 2011
  97. Published

    Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

    Christoffersen, Christina, Obinata, H., Kumaraswamy, S. B., Galvani, S., Ahnström, J., Sevvana, M., Egerer-Sieber, C., Muller, Y. A., Hla, T., Nielsen, L. B. & Dahlbäck, B., 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 23, p. 9613-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. 2010
  99. Published

    Opposing effects of apolipoprotein m on catabolism of apolipoprotein B-containing lipoproteins and atherosclerosis

    Christoffersen, Christina, Pedersen, T. X., Gordts, P. L. S. M., Roebroek, A. J. M., Dahlbäck, B. & Nielsen, L. B., 2010, In: Circulation Research. 106, 10, p. 1624-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. 2009
  101. Published

    Heparininduceret trombocytopeni

    Christoffersen, Christina, Lethagen, S. & Goetze, Jens P. , 16 Feb 2009, In: Ugeskrift for Laeger. 171, 8, p. 612-5 4 p.

    Research output: Contribution to journalJournal articleResearch

  102. Published

    ApoM: gene regulation and effects on HDL metabolism

    Nielsen, L. B., Christoffersen, Christina, Ahnström, J. & Dahlbäck, B., 2009, In: Trends in Endocrinology and Metabolism. 20, 2, p. 66-71 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. 2008
  104. Published

    Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice

    Christoffersen, Christina, Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlbäck, B. & Nielsen, L. B., 25 Jan 2008, In: The Journal of Biological Chemistry. 283, 4, p. 1839-47 9 p.

    Research output: Contribution to journalJournal articleResearch

  105. Published

    Apolipoprotein M: Structure and Function

    Dahlback, B., Ahnstrom, J., Christoffersen, Christina & Nielsen, L. B., 2008, In: Future Lipidology. 3, p. 495-503

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    The signal peptide anchors apolipoprotein M in plasma lipoproteins and prevents rapid clearance of apolipoprotein M from plasma

    Christoffersen, Christina, Ahnström, J., Axler, O., Christensen, E. I., Dahlbäck, B. & Nielsen, L. B., 2008, In: Journal of Biological Chemistry. 283, 27, p. 18765-72 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    The signal peptide anchors apolipoprotein m in plasma lipoproteins and prevents rapid clearance of apolipoprotein m from plasma

    Christoffersen, Christina, Ahnstrom, J., Axler, O., Christensen, E. I., Dahlback, B. & Nielsen, L. B., 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 6, p. E62-E63

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. 2007
  109. Published

    Diabetes and the endocrine heart

    Christoffersen, Christina, Hunter, I., Jensen, Asger Lundorff & Goetze, Jens P. , Oct 2007, In: European Heart Journal. 28, 20, p. 2427-9 3 p.

    Research output: Contribution to journalEditorialResearch

  110. 2006
  111. Published

    Isolation and characterization of human apolipoprotein M-containing lipoproteins

    Christoffersen, Christina, Nielsen, L. B., Axler, O., Andersson, A., Johnsen, A. H. & Dahlbäck, B., Aug 2006, In: Journal of Lipid Research. 47, 8, p. 1833-43 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Heart specific up-regulation of genes for B-type and C-type natriuretic peptide receptors in diabetic mice

    Christoffersen, Christina, Bartels, Emil Daniel & Nielsen, L. B., Feb 2006, In: European Journal of Clinical Investigation. 36, 2, p. 69-75 7 p.

    Research output: Contribution to journalJournal articleResearch

  113. Published

    Apolipoprotein M: progress in understanding its regulation and metabolic functions

    Christoffersen, Christina, Dahlbäck, B. & Nielsen, L. B., 2006, In: Scandinavian Journal of Clinical & Laboratory Investigation. 66, 7, p. 631-7 7 p.

    Research output: Contribution to journalJournal articleResearch

  114. 2005
  115. Published

    Endothelial and lipoprotein lipases in human and mouse placenta

    Lindegaard, M. L. S., Olivecrona, G., Christoffersen, Christina, Kratky, D., Hannibal, Jens, Petersen, B. L., Zechner, R., Damm, Peter & Nielsen, L. B., 1 Nov 2005, In: Journal of Lipid Research. 46, 11, p. 2339-46 8 p.

    Research output: Contribution to journalJournal articleResearch

  116. Published

    Endothelial and lipoprotein lipases in human and mouse placenta

    Lindegaard, M. L. S., Olivecrona, G., Christoffersen, Christina, Kratky, D., Hannibal, Jens, Petersen, B. L., Zechner, R., Damm, Peter & Nielsen, L. B., Nov 2005, In: Journal of Lipid Research. 46, 11, p. 2339-46 8 p.

    Research output: Contribution to journalJournal articleResearch

  117. 2003
  118. Published

    Cardiac lipid accumulation associated with diastolic dysfunction in obese mice

    Christoffersen, Christina, Bollano, E., Lindegaard, M. L. S., Bartels, Emil Daniel, Goetze, Jens P. , Andersen, C. B. & Nielsen, L. B., Aug 2003, In: Molecular Endocrinology. 144, 8, p. 3483-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Published

    Increased cardiac BNP expression associated with myocardial ischemia

    Goetze, Jens P. , Christoffersen, Christina, Perko, M., Arendrup, H., Rehfeld, Jens Frederik, Kastrup, J. & Nielsen, L. B., Jun 2003, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 9, p. 1105-7 3 p.

    Research output: Contribution to journalJournal articleResearch

  120. 2002
  121. Published

    Chamber-dependent expression of brain natriuretic peptide and its mRNA in normal and diabetic pig heart

    Christoffersen, Christina, Goetze, Jens P. , Bartels, Emil Daniel, Larsen, T. M., Ribel, U., Rehfeld, Jens Frederik, Rolin, B. & Nielsen, L. B., Jul 2002, In: Hypertension. 40, 1, p. 54-60 7 p.

    Research output: Contribution to journalJournal articleResearch

ID: 18392597