Cerebral net exchange of large neutral amino acids after lipopolysaccharide infusion in healthy humans
Research output: Contribution to journal › Journal article › Research › peer-review
Alterations in circulating large neutral amino acids (LNAAs), leading to a decrease in the plasma ratio between branched-chain and aromatic amino acids (BCAA/AAA ratio), may be involved in sepsis-associated encephalopathy. We hypothesised that a decrease in the BCAA/AAA ratio occurs along with a net cerebral influx of the neurotoxic AAA phenylalanine in a human experimental model of systemic inflammation.
Original language | English |
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Journal | Critical Care |
Volume | 14 |
Issue number | 1 |
Pages (from-to) | R16 |
ISSN | 1574-4280 |
DOIs | |
Publication status | Published - 1 Jan 2010 |
ID: 34113389