Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects

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Standard

Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects. / Holmer-Jensen, Jens; Mortensen, Lene Sundahl; Astrup, Arne; de Vrese, Michael; Holst, Jens Juul; Thomsen, Claus; Hermansen, Kjeld.

In: Nutrition Research, Vol. 33, No. 1, 2013, p. 34-40.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Holmer-Jensen, J, Mortensen, LS, Astrup, A, de Vrese, M, Holst, JJ, Thomsen, C & Hermansen, K 2013, 'Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects', Nutrition Research, vol. 33, no. 1, pp. 34-40. https://doi.org/10.1016/j.nutres.2012.11.004

APA

Holmer-Jensen, J., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, J. J., Thomsen, C., & Hermansen, K. (2013). Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects. Nutrition Research, 33(1), 34-40. https://doi.org/10.1016/j.nutres.2012.11.004

Vancouver

Holmer-Jensen J, Mortensen LS, Astrup A, de Vrese M, Holst JJ, Thomsen C et al. Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects. Nutrition Research. 2013;33(1):34-40. https://doi.org/10.1016/j.nutres.2012.11.004

Author

Holmer-Jensen, Jens ; Mortensen, Lene Sundahl ; Astrup, Arne ; de Vrese, Michael ; Holst, Jens Juul ; Thomsen, Claus ; Hermansen, Kjeld. / Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects. In: Nutrition Research. 2013 ; Vol. 33, No. 1. pp. 34-40.

Bibtex

@article{df4b6415992643e9a30e6b51fd149254,
title = "Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects",
abstract = "Non-fasting triglyceridemia is much closer associated to cardiovascular risk compared to fasting triglyceridemia. We hypothesized that there would be acute differential effects of four common dietary proteins (cod protein, whey isolate, gluten, and casein) on postprandial lipemia in obese non-diabetic subjects. To test the hypothesis we conducted a randomized, acute clinical intervention study with crossover design. We supplemented a fat rich mixed meal with one of four dietary proteins i.e. cod protein, whey protein, gluten or casein. Eleven obese non-diabetic subjects (age: 40-68, body mass index: 30.3-42.0 kg/m(2)) participated and blood samples were drawn in the 8-h postprandial period. Supplementation of a fat rich mixed meal with whey protein caused lower postprandial lipemia (P = .048) compared to supplementation with cod protein and gluten. This was primarily due to lower triglyceride concentration in the chylomicron rich fraction (P = .0293). Thus, we have demonstrated acute differential effects on postprandial metabolism of four dietary proteins supplemented to a fat rich mixed meal in obese non-diabetic subjects. Supplementation with whey protein caused lower postprandial lipemia compared to supplementation with cod and gluten. As postprandial lipemia is closely correlated to cardiovascular disease, long-term dietary supplementation with whey protein may prove beneficial in preventing cardiovascular disease in obese non-diabetic subjects.",
author = "Jens Holmer-Jensen and Mortensen, {Lene Sundahl} and Arne Astrup and {de Vrese}, Michael and Holst, {Jens Juul} and Claus Thomsen and Kjeld Hermansen",
note = "CURIS 2013 NEXS 067",
year = "2013",
doi = "10.1016/j.nutres.2012.11.004",
language = "English",
volume = "33",
pages = "34--40",
journal = "Nutrition Research",
issn = "0271-5317",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects

AU - Holmer-Jensen, Jens

AU - Mortensen, Lene Sundahl

AU - Astrup, Arne

AU - de Vrese, Michael

AU - Holst, Jens Juul

AU - Thomsen, Claus

AU - Hermansen, Kjeld

N1 - CURIS 2013 NEXS 067

PY - 2013

Y1 - 2013

N2 - Non-fasting triglyceridemia is much closer associated to cardiovascular risk compared to fasting triglyceridemia. We hypothesized that there would be acute differential effects of four common dietary proteins (cod protein, whey isolate, gluten, and casein) on postprandial lipemia in obese non-diabetic subjects. To test the hypothesis we conducted a randomized, acute clinical intervention study with crossover design. We supplemented a fat rich mixed meal with one of four dietary proteins i.e. cod protein, whey protein, gluten or casein. Eleven obese non-diabetic subjects (age: 40-68, body mass index: 30.3-42.0 kg/m(2)) participated and blood samples were drawn in the 8-h postprandial period. Supplementation of a fat rich mixed meal with whey protein caused lower postprandial lipemia (P = .048) compared to supplementation with cod protein and gluten. This was primarily due to lower triglyceride concentration in the chylomicron rich fraction (P = .0293). Thus, we have demonstrated acute differential effects on postprandial metabolism of four dietary proteins supplemented to a fat rich mixed meal in obese non-diabetic subjects. Supplementation with whey protein caused lower postprandial lipemia compared to supplementation with cod and gluten. As postprandial lipemia is closely correlated to cardiovascular disease, long-term dietary supplementation with whey protein may prove beneficial in preventing cardiovascular disease in obese non-diabetic subjects.

AB - Non-fasting triglyceridemia is much closer associated to cardiovascular risk compared to fasting triglyceridemia. We hypothesized that there would be acute differential effects of four common dietary proteins (cod protein, whey isolate, gluten, and casein) on postprandial lipemia in obese non-diabetic subjects. To test the hypothesis we conducted a randomized, acute clinical intervention study with crossover design. We supplemented a fat rich mixed meal with one of four dietary proteins i.e. cod protein, whey protein, gluten or casein. Eleven obese non-diabetic subjects (age: 40-68, body mass index: 30.3-42.0 kg/m(2)) participated and blood samples were drawn in the 8-h postprandial period. Supplementation of a fat rich mixed meal with whey protein caused lower postprandial lipemia (P = .048) compared to supplementation with cod protein and gluten. This was primarily due to lower triglyceride concentration in the chylomicron rich fraction (P = .0293). Thus, we have demonstrated acute differential effects on postprandial metabolism of four dietary proteins supplemented to a fat rich mixed meal in obese non-diabetic subjects. Supplementation with whey protein caused lower postprandial lipemia compared to supplementation with cod and gluten. As postprandial lipemia is closely correlated to cardiovascular disease, long-term dietary supplementation with whey protein may prove beneficial in preventing cardiovascular disease in obese non-diabetic subjects.

U2 - 10.1016/j.nutres.2012.11.004

DO - 10.1016/j.nutres.2012.11.004

M3 - Journal article

C2 - 23351408

VL - 33

SP - 34

EP - 40

JO - Nutrition Research

JF - Nutrition Research

SN - 0271-5317

IS - 1

ER -

ID: 44866205