Vilhelm Bohr
Affiliate professor, Affiliate Professor
Molecular Aging Program
Panum Instituttet, Blegdamsvej 3, 2200 København N, 07 Bygning 7, Building: 07-3-13
Member of:
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Lamin A/C promotes DNA base excision repair
Maynard, S., Keijzers, G., Akbari, M., Ben Ezra, Michael, Hall, A., Morevati, M., Scheibye-Knudsen, Morten, Gonzalo, S., Bartek, J. & Bohr, Vilhelm, 2019, In: Nucleic Acids Research. 47, 22, p. 11709–11728Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions
Liu, D., Croteau, D. L., Souza-Pinto, N., Pitta, M., Tian, J., Wu, C., Jiang, H., Mustafa, K., Keijzers, G., Bohr, Vilhelm & Mattson, M. P., Feb 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 2, p. 680-692 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Earl R. Stadtman
Levine, R. L. & Bohr, Vilhelm, 1 Jan 2010, In: Mechanisms of Ageing and Development. 131, 1, p. 1Research output: Contribution to journal › Journal article › Research › peer-review
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Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms
Massip, L., Garand, C., Labbé, A., Perreault, E., Turaga, R. V. N., Bohr, Vilhelm & Lebel, M., 11 Mar 2010, In: Oncogene. 29, 10, p. 1486-97 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human RecQL4 helicase plays critical roles in prostate carcinogenesis
Su, Y., Meador, J. A., Calaf, G. M., Proietti De-Santis, L., Zhao, Y., Bohr, Vilhelm & Balajee, A. S., 15 Nov 2010, In: Cancer Research. 70, 22, p. 9207-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
Soerensen, M., Dato, S., Christensen, K., McGue, M., Stevnsner, T. V., Bohr, Vilhelm & Christiansen, L., 1 Dec 2010, In: Aging Cell. 9, 6, p. 1010-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells
Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
Hou, Y., Lautrup, S., Cordonnier, S., Wang, Y., Croteau, D. L., Zavala, E., Zhang, Y., Moritoh, K., O’Connell, J. F., Baptiste, B. A., Stevnsner, T. V., Mattson, M. P. & Bohr, Vilhelm, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 8, p. E1876-E1885Research output: Contribution to journal › Journal article › Research › peer-review
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Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
Maynard, S., Keijzers, G., Gram, M., Desler, Claus, Bendix, L., Budtz-Joergensen, Esben, Molbo, Drude, Croteau, D. L., Osler, Merete, Stevnsner, T. V., Rasmussen, Lene Juel, Dela, Flemming, Avlund, K. & Bohr, Vilhelm, 30 Nov 2013, In: Aging. p. 850-864 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling
Okur, M. N., Fang, E. F., Fivenson, E. M., Tiwari, V., Croteau, D. L. & Bohr, Vilhelm, Dec 2020, In: Aging Cell. 19, 12, p. e13268Research output: Contribution to journal › Journal article › Research › peer-review
Emerging Antitumor Activities of the Bitter Melon (Momordica charantia)
Fang, E. F., Froetscher, L., Scheibye-Knudsen, Morten, Bohr, Vilhelm, Wong, J. H. & Ng, T. B., 2019, In: Current Protein and Peptide Science. 20, 3, p. 296-301 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
Fang, E. F., Palikaras, K., Sun, N., Fivenson, E. M., Spangler, R. D., Kerr, J. S., Cordonnier, S. A., Hou, Y., Dombi, E., Kassahun, H., Tavernarakis, N., Poulton, J., Nilsen, H. & Bohr, Vilhelm, 2017, In: Journal of Visualized Experiments. 129, e56301.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli
Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516Research output: Contribution to journal › Journal article › Research › peer-review
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Cytosolic self-DNA—A potential source of chronic inflammation in aging
Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.Research output: Contribution to journal › Review › Research › peer-review
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Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells
Akbari, M., Sykora, P. & Bohr, Vilhelm, 10 Aug 2015, In: Scientific Reports. 5, 8 p., 12876 .Research output: Contribution to journal › Journal article › Research › peer-review
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Ageing as a risk factor for neurodegenerative disease
Hou, Y., Dan, X., Babbar, M., Wei, Y., Hasselbalch, Steen, Croteau, D. L. & Bohr, Vilhelm, 2019, In: Nature Reviews. Neurology. 15, 10, p. 565-581 17 p.Research output: Contribution to journal › Review › Research › peer-review
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The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.Research output: Contribution to journal › Journal article › Research › peer-review
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Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase
Muftuoglu, M., de Souza-Pinto, N. C., Dogan, A., Aamann, M., Stevnsner, T., Rybanska, I., Kirkali, G., Dizdaroglu, M. & Bohr, Vilhelm, Apr 2009, In: Journal of Biological Chemistry. 284, 14, p. 9270-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells
de Souza-Pinto, N. C., Maynard, S., Hashiguchi, K., Hu, J., Muftuoglu, M. & Bohr, Vilhelm, Aug 2009, In: Molecular and Cellular Biology. 29, 16, p. 4441-54 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane
Aamann, M. D., Sorensen, M. M., Hvitby, C. P., Berquist, B. R., Muftuoglu, M., Tian, J., de Souza-Pinto, N. C., Scheibye-Knudsen, M., Wilson, D. M., Stevnsner, T. V. & Bohr, Vilhelm, 1 Jul 2010, In: The FASEB Journal. 24, 7, p. 2334-46 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1
Rhee, D. B., Ghosh, A., Lu, J., Bohr, Vilhelm & Liu, Y., 2 Jan 2011, In: DNA Repair. 10, 1, p. 34-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
McCord, R. A., Michishita, E., Hong, T., Berber, E., Boxer, L. D., Kusumoto, R., Guan, S., Shi, X., Gozani, O., Burlingame, A. L., Bohr, Vilhelm & Chua, K. F., 1 Jan 2009, In: Aging. 1, 1, p. 109-21 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples
Lachapelle, S., Gagné, J., Garand, C., Desbiens, M., Coulombe, Y., Bohr, Vilhelm, Hendzel, M. J., Masson, J., Poirier, G. G. & Lebel, M., 4 Mar 2011, In: Journal of Proteome Research. 10, 3, p. 1216-27 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human embryonic stem cells have enhanced repair of multiple forms of DNA damage
Maynard, S., Swistowska, A. M., Lee, J. W., Liu, Y., Liu, S., Da Cruz, A. B., Rao, M., de Souza-Pinto, N. C., Zeng, X. & Bohr, Vilhelm, 1 Sep 2008, In: Stem Cells. 26, 9, p. 2266-74 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity
Croteau, D. L., Rossi, M. L., Canugovi, C., Tian, J., Sykora, P., Ramamoorthy, M., Wang, Z. M., Singh, D. K., Akbari, M., Kasiviswanathan, R., Copeland, W. C. & Bohr, Vilhelm, 2012, In: Aging Cell. 11, 3, p. 456-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4975983
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Mitochondria in the signaling pathways that control longevity and health span
Research output: Contribution to journal › Review › Research › peer-review
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281
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Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Research output: Contribution to journal › Journal article › Research › peer-review
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251
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Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Research output: Contribution to journal › Journal article › Research › peer-review
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