Thue W. Schwartz

Thue W. Schwartz

Professor

Member of:

    ORCID: 0000-0002-0261-6904

    Publication year:
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    76 - 100 out of 258Page size: 25
    1. 2015
    2. Published

      The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage

      Knudsen, L. A., Petersen, N., Schwartz, Thue W. & Egerod, Kristoffer Lihme, Nov 2015, In: Endocrinology. 156, 11, p. 3971-83 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells

      Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Biased Gs Versus Gq Proteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network

      Valentin-Hansen, L., Frimurer, Thomas Michael, Mokrosinski, J., Holliday, N. D. & Schwartz, Thue W., 2 Oct 2015, In: The Journal of Biological Chemistry. 290, 40, p. 24495-508 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1

      Manfra, O., Van Craenenbroeck, K., Skieterska, K., Frimurer, Thomas Michael, Schwartz, Thue W., Levy, F. O. & Andressen, K. W., Jul 2015, In: A C S Chemical Neuroscience. 6, 7, p. 1206–1218 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Ghrelin

      Mueller, T. D., Nogueiras, R., Andermann, M. L., Andrews, Z. B., Anker, S. D., Argente, J., Batterham, R. L., Benoit, S. C., Bowers, C. Y., Broglio, F., Casanueva, F. F., D'Alessio, D., Depoortere, I., Geliebter, A., Ghigo, E., Cole, P. A., Cowley, M., Cummings, D. E., Dagher, A., Diano, S. & 37 others, Dickson, S. L., Dieguez, C., Granata, R., Grill, H. J., Grove, K., Habegger, K. M., Heppner, K., Heiman, M. L., Holsen, L., Holst, Birgitte, Inui, A., Jansson, J. O., Kirchner, H., Korbonits, M., Laferrere, B., LeRoux, C. W., Lopez, M., Morin, S., Nakazato, M., Nass, R., Perez-Tilve, D., Pfluger, P. T., Schwartz, Thue W., Seeley, R. J., Sleeman, M., Sun, Y., Sussel, L., Tong, J., Thorner, M. O., van der Lely, A. J., van der Ploeg, L. H. T., Zigman, J. M., Kojima, M., Kangawa, K., Smith, R. G., Horvath, T. & Tschoep, M. H., Jun 2015, In: Molecular Metabolism. 4, 6, p. 437-460 24 p.

      Research output: Contribution to journal › Review › Research › peer-review

    7. Published

      Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia

      Nøhr, M. K., Egerod, Kristoffer Lihme, Christiansen, S. H., Gille, A., Offermanns, S., Schwartz, Thue W. & Møller, Morten, 2 Apr 2015, In: Neuroscience. 290, p. 126-37 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease

      Ádori, C., Glück, L., Barde, S., Yoshitake, T., Kovacs, G. G., Mulder, J., Maglóczky, Z., Havas, L., Bölcskei, K., Mitsios, N., Uhlén, M., Szolcsányi, J., Kehr, J., Rönnbäck, A., Schwartz, Thue W., Rehfeld, Jens Frederik, Harkany, T., Palkovits, M., Schulz, S. & Hökfelt, T., Apr 2015, In: Acta Neuropathologica. 129, 4, p. 541-63 23 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors

      Hamann, J., Aust, G., Araç, D., Engel, F. B., Formstone, C., Fredriksson, R., Hall, R. A., Harty, B. L., Kirchhoff, C., Knapp, B., Krishnan, A., Liebscher, I., Lin, H-H., Martinelli, D. C., Monk, K. R., Cornelia Peeters, M., Piao, X., Prömel, S., Schöneberg, T., Schwartz, T. W. & 9 others, Singer, K., Stacey, M., Ushkaryov, Y. A., Vallon, M., Wolfrum, U., Wright, M. W., Xu, L., Langenhan, T. & Schiöth, H. B., Apr 2015, In: Pharmacological Reviews. 67, 2, p. 338-67 30 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

      Pedersen, M. H., Bentsen, M. A., Husted, Anna Sofie, Ekberg, J. P., Wright, M. J., Di Salvo, J., Weinglass, A. B., Engelstoft, M. S., Madsen, A. N., Lückmann, Michael, Miller, M. W., Trujillo, M. E., Frimurer, Thomas Michael, Holst, Birgitte, Howard, A. D. & Schwartz, Thue W., Jan 2015, In: Molecular Metabolism. 4, 1, p. 3-14 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Mutation-Guided Unbiased Modeling of the Fat Sensor GPR119 for High-Yield Agonist Screening.

      Norn, C., Pedersen, M. H., Engelstoft, M. S., Kim, S. H., Lehmann, J., Jones, R. M., Schwartz, Thue W. & Frimurer, Thomas Michael, 2015, In: Structure. 23, 12, p. 2377-2386 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. 2014
    13. Published

      The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

      Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119

      Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Bioorthogonal fluorescent labeling of functional G-protein-coupled receptors

      Tian, H., Naganathan, S., Kazmi, M. A., Schwartz, Thue W., Sakmar, T. P. & Huber, T., 18 Aug 2014, In: ChemBioChem. 15, 12, p. 1820-9 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Mapping Substance P Binding Sites on the Neurokinin-1 Receptor Using Genetic Incorporation of a Photoreactive Amino Acid

      Valentin-Hansen, L., Park, M., Huber, T., Grunbeck, A., Naganathan, S., Schwartz, Thue W. & Sakmar, T. P., 27 Jun 2014, In: The Journal of Biological Chemistry. 289, 26, p. 18045-54 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Effects of PYY3-36 and GLP-1 on energy intake, energy expenditure and appetite in overweight men

      Schmidt, J. B., Gregersen, N. T., Pedersen, S. D., Arentoft, J. L., Ritz, C., Schwartz, Thue W., Holst, Jens Juul, Astrup, A. & Sjödin, Anders Mikael, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 11, p. E1248-E1256 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. 2013
    19. Published

      Enteroendocrine cell types revisited

      Engelstoft, M. S., Egerod, Kristoffer Lihme, Lund, M. L. & Schwartz, Thue W., Dec 2013, In: Current Opinion in Pharmacology. 13, 6, p. 912-21 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

      Engelstoft, M. S., Park, W-M., Sakata, I., Kristensen, L. V., Husted, A. S., Osborne-Lawrence, S., Piper, P. K., Walker, A. K., Pedersen, M. H., Nøhr, M. K., Pan, J., Sinz, C. J., Carrington, P. E., Akiyama, T. E., Jones, R. M., Tang, C., Ahmed, K., Offermanns, S., Egerod, K. L., Zigman, J. M. & 1 others, Schwartz, Thue W., Nov 2013, In: Molecular Metabolism. 2, 4, p. 376-92 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

      Nøhr, M. K., Pedersen, M. H., Gille, A., Egerod, Kristoffer Lihme, Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R. M., Grunddal, Kaare Villum, Poulsen, Steen Seier, Han, S., Jones, R. M., Offermanns, S. & Schwartz, Thue W., 24 Jul 2013, In: Endocrinology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells

      Pedersen, J., Ugleholdt, Randi Kjærsgaard, Jørgensen, S. M., Windeløv, Johanne Agerlin, Grunddal, Kaare Villum, Schwartz, Thue W., Füchtbauer, E., Poulsen, Steen Seier, Holst, Peter Johannes & Holst, Jens Juul, 1 Jan 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 1, p. E60-73 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

      Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Groves, C. J., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, Johanne Marie, Kristiansen, Karsten, Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liang, H., Liao, Q., Liu, X., Ma, T., Ma, X., Manijak, M. P., Marre, M., Mokrosinski, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, Thue W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., Van't Riet, E., van Leeuwen, N., V Varga, Tibor, Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., 't Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions

      Møller, T. C., Wirth, V. F., Roberts, N. I., Bender, J., Bach, Anders, Jacky, B. P. S., Strømgaard, Kristian, Deussing, J. M., Schwartz, Thue W. & Martinez, Karen Laurence, 2013, In: PLOS ONE. 8, 5, e63352.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2012
    26. Published

      PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation

      Valentin-Hansen, L., Holst, Birgitte, Frimurer, Thomas Michael, Schwartz, Thue W. & Hansen, L. V., 21 Dec 2012, In: Journal of Biological Chemistry. 287, 52, p. 43516-43526 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

      Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Dissecting signaling and functions of adhesion G protein-coupled receptors

      Araç, D., Aust, G., Calebiro, D., Engel, F. B., Formstone, C., Goffinet, A., Hamann, J., Kittel, R. J., Liebscher, I., Lin, H-H., Monk, K. R., Petrenko, A., Piao, X., Prömel, S., Schiöth, H. B., Schwartz, T. W., Stacey, M., Ushkaryov, Y. A., Wobus, M., Wolfrum, U. & 2 others, Xu, L. & Langenhan, T., Dec 2012, In: Annals of the New York Academy of Sciences. 1276, p. 1-25 25 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor

      Hansen, L. V., Groenen, M., Nygaard, R., Frimurer, Thomas Michael, Holliday, N. D. & Schwartz, Thue W., 14 Sep 2012, In: Journal of Biological Chemistry. 287, 38, p. 31973-82 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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