Thomas Werge

Thomas Werge

Clinical Professor

Member of:

  • Psychiatry


  1. 2021
  2. Published

    Copy Number Variants and Polygenic Risk Scores Predict Need of Care in Autism and/or ADHD Families

    LaBianca, S., LaBianca, J., Pagsberg, Anne Katrine, Jakobsen, K. D., Appadurai, V., Buil, A. & Werge, Thomas, Jan 2021, In: Journal of Autism and Developmental Disorders. 51, 1, p. 276-285 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

    Bell, S., Rigas, A. S., Magnusson, M. K., Ferkingstad, E., Allara, E., Bjornsdottir, G., Ramond, A., Sørensen, E., Halldorsson, G. H., Paul, D. S., Burgdorf, K. S., Eggertsson, H. P., Howson, J. M. M., Thørner, L. W., Kristmundsdottir, S., Astle, W. J., Erikstrup, C., Sigurdsson, J. K., Vuckovic, D., Dinh, K. M. & 31 others, Tragante, V., Surendran, P., Pedersen, Ole Birger Vesterager, Vidarsson, B., Jiang, T., Paarup, H. M., Onundarson, P. T., Akbari, P., Nielsen, K. R., Lund, S. H., Juliusson, K., Magnusson, M. I., Frigge, M. L., Oddsson, A., Olafsson, I., Kaptoge, S., Hjalgrim, Henrik, Runarsson, G., Wood, A. M., Hansen, Thomas Folkmann, Burgdorf, Kristoffer Sølvsten, Jemec, Gregor, Jennum, Poul, Nielsen, K. R., Petersen, M., Werge, Thomas, Westergaard, David, Banasik, Karina, Brunak, Søren, Ullum, H. & DBDS Genomic Consortium, D. G. C., 2021, In: Communications Biology . 4, 1, 14 p., 156.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders

    Nudel, R., Allesøe, R. L., Thompson, W. K., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2021, In: Journal of Translational Medicine. 19, 230.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A polygenic resilience score moderates the genetic risk for schizophrenia

    Hess, J. L., Tylee, D. S., Mattheisen, M., The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum, A. D., Als, T. D., Grove, J., Werge, T., Mortensen, P. B., Mors, O., Nordentoft, M., Hougaard, D. M., Byberg-grauholm, J., Bækvad-hansen, M., Greenwood, T. A., Tsuang, M. T., Curtis, D., Steinberg, S., Sigurdsson, E. & 6 others, Stefánsson, H., Stefánsson, K., Edenberg, H. J., Holmans, P., Faraone, S. V. & Glatt, S. J., 2021, In: Molecular Psychiatry. 26, p. 800–815

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Association and genetic overlap between clinical chemistry tests and migraine

    Tanha, H. M. & The International Headache Genetics Consortium (IHGC), T. I. H. G. C. (., 2021, In: Cephalalgia. 41, 11-12, p. 1208-1221 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

    Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 46 others, Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Cervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Del Zompo, M., DePaulo, J. R., Étain, B., Jamain, S., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Nordentoft, Merete, Werge, Thomas, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Wray, N. R., Ripke, S., Matthiesen, M., Agerbo, E., Bækvad-Hansen, M., Buttenschøn, H. N., Bybjerg-Grauholm, J., Grove, J., Hansen, C. S., Hansen, T. F., Hougaard, D. M., Krogh, J., Pedersen, C. B., Pedersen, M. G., Qvist, P., Thompson, W. K., Wang, Y., Weinsheimer, S. M., Mortensen, P. B., Christensen, J. V. & Børglum, A. D., 2021, In: Molecular Psychiatry. 26, p. 2457–2470 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors

    Krebs, M. D., Themudo, G. E., Benros, Michael Eriksen, Mors, O., Børglum, A. D., Hougaard, D., Mortensen, P. B., Nordentoft, Merete, Gandal, M. J., Fan, C. C., Geschwind, D. H., Schork, A. J., Werge, Thomas & Thompson, W. K., 2021, In: Nature Communications. 12, 12 p., 6617.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

    Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, Treutlein, J., Witt, S. H., Cichon, S., Kogevinas, M., Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pers, Tune H, Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Nordentoft, Merete, Werge, Thomas, Hansen, Thomas Folkmann, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    CYP2D6 Genotyping and Antipsychotic-Associated Extrapyramidal Adverse Effects in a Randomized Trial of Aripiprazole Versus Quetiapine Extended Release in Children and Adolescents, Aged 12-17 Years, With First Episode Psychosis

    Rudå, Ditte, mfw347, mfw347, Decara, M. S., Klauber, D. G., Fagerlund, Birgitte, Møllegaard, J. R., Linnet, Kristian, Werge, Thomas, Correll, C. U., Fink-Jensen, Anders, Jürgens, Gesche & Pagsberg, Anne Katrine, 2021, In: Journal of Clinical Psychopharmacology. 41, 6, p. 667-672

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study

    Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Grove, J., Nordentoft, Merete, Børglum, A. D., Mortensen, P. B., Werge, Thomas, Melbye, M., Hougaard, D. M. & Christiansen, M., 2021, In: Journal of Neurodevelopmental Disorders. 13, 9 p., 19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits

    Martin, J., Khramtsova, E. A., Goleva, S. B., Blokland, G. A. M., Traglia, M., Walters, R. K., Hübel, C., Coleman, J. R. I., Breen, G., Børglum, A. D., Demontis, D., Grove, J., Werge, T., Bralten, J., Bulik, C. M., Lee, P. H., Mathews, C. A., Peterson, R. E., Winham, S. J., Wray, N. & 13 others, Edenberg, H. J., Guo, W., Yao, Y., Neale, B. M., Faraone, S. V., Petryshen, T. L., Weiss, L. A., Duncan, L. E., Goldstein, J. M., Smoller, J. W., Stranger, B. E., Davis, L. K. & Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, S. D. C. A. G. O. T. P. G. C., 2021, In: Biological Psychiatry. 89, 12, p. 1127-1137

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Genetic disposition towards educational attainment and intelligence test performance predict voter turnout

    Aaroe, L., Appadurai, V., Hansen, Kasper Møller, Schork, A. J., Werge, Thomas, Mors, O., Borglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Thompson, W. K., Buil, A., Agerbo, E. & Petersen, M. B., 2021, In: Nature Human Behavior. 5, 2, p. 281-291 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study: [Incl. Corrigendum]

    Liu, X., Nudel, R., Thompson, W. K., Appadurai, V., Schork, A. J., Buil, A., Rasmussen, Simon, Allesøe, R. L., Werge, Thomas, Mors, O., Børglum, A. D., Hougaard, D. M., Mortensen, P. B., Nordentoft, Merete & Benros, Michael Eriksen, 2021, In: Brain, Behavior, and Immunity. 91, p. 10-23 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study

    Fadista, J., Yakimov, V., Võsa, U., Hansen, C. S., Kasela, S., Skotte, L., Geller, F., Courraud, J., Esko, T., Kukuškina, V., Buil, A., Melbye, M., Werge, Thomas, Hougaard, D. M., Milani, L., Bybjerg-Grauholm, J., Cohen, A. S. & Feenstra, B., 2021, In: Scientific Reports. 11, 17463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD

    Brikell, I., Wimberley, T., Albinana, C., Pedersen, E. M., Vilhjalmsson, B. J., Agerbo, E., Demontis, D., Borglum, A. D., Schork, A. J., LaBianca, S., Werge, Thomas, Mors, O., Hougaard, D. M., Thapar, A., Mortensen, P. B. & Dalsgaard, S., 2021, In: American Journal of Psychiatry. 178, 9, p. 854-864 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci

    Foss-Skiftesvik, J., Hagen, C. M., Mathiasen, R., Adamsen, D., Bækvad-Hansen, M., Børglum, A. D., Nordentoft, Merete, Werge, Thomas, Christiansen, M., Schmiegelow, Kjeld, Juhler, Marianne, Mortensen, P. B., Hougaard, D. M. & Bybjerg-Grauholm, J., 2021, In: Child's Nervous System. 37, p. 819–830

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Genome-wide association study identifies 48 common genetic variants associated with handedness

    Cuellar-Partida, G., Tung, J. Y., Eriksson, N., Albrecht, E., Aliev, F., Andreassen, O. A., Barroso, I., Beckmann, J. S., Boks, M. P., Boomsma, D. I., Boyd, H. A., Breteler, M. M. B., Campbell, H., Chasman, D. I., Cherkas, L. F., Davies, G., de Geus, E. J. C., Deary, I. J., Deloukas, P., Dick, D. M. & 98 others, Duffy, D. L., Eriksson, J. G., Esko, T., Feenstra, B., Geller, F., Gieger, C., Giegling, I., Gordon, S. D., Han, J., Hansen, T. F., Hartmann, A. M., Hayward, C., Heikkila, K., Hicks, A. A., Hirschhorn, J. N., Hottenga, J., Huffman, J. E., Hwang, L., Ikram, M. A., Kaprio, J., Kemp, J. P., Khaw, K., Klopp, N., Konte, B., Kutalik, Z., Lahti, J., Li, X., Loos, Ruth, Luciano, M., Magnusson, S. H., Mangino, M., Marques-Vidal, P., Martin, N. G., McArdle, W. L., McCarthy, M. I., Medina-Gomez, C., Melbye, M., Melville, S. A., Metspalu, A., Milani, L., Mooser, V., Nelis, M., Nyholt, D. R., O'Connell, K. S., Ophoff, R. A., Palmer, C., Palotie, A., Palviainen, T., Pare, G., Paternoster, L., Peltonen, L., Penninx, B. W. J. H., Polasek, O., Pramstaller, P. P., Prokopenko, I., Raikkonen, K., Ripatti, S., Rivadeneira, F., Rudan, I., Rujescu, D., Smit, J. H., Smith, G. D., Smoller, J. W., Soranzo, N., Spector, T. D., Pourcain, B. S., Starr, J. M., Stefansson, H., Steinberg, S., Teder-Laving, M., Thorleifsson, G., Stefansson, K., Timpson, N. J., Uitterlinden, A. G., van Duijn, C. M., van Rooij, F. J. A., Vink, J. M., Vollenweider, P., Vuoksimaa, E., Waeber, G., Wareham, N. J., Warrington, N., Waterworth, D., Werge, Thomas, Wichmann, H. -., Widen, E., Willemsen, G., Wright, A. F., Wright, M. J., Xu, M., Zhao, J. H., Kraft, P., Hinds, D. A., Lindgren, C. M., Magi, R., Neale, B. M., Evans, D. M. & Medland, S. E., 2021, In: Nature Human Behaviour. 5, p. 59-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    HUNT All-In Psychiatry, H. A. P., 2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

    Forstner, A. J., Awasthi, S., Wolf, C., Maron, E., Erhardt, A., Czamara, D., Eriksson, E., Lavebratt, C., Allgulander, C., Friedrich, N., Becker, J., Hecker, J., Rambau, S., Conrad, R., Geiser, F., Mcmahon, F. J., Moebus, S., Hess, T., Buerfent, B. C., Hoffmann, P. & 55 others, Herms, S., Heilmann-heimbach, S., Kockum, I., Olsson, T., Alfredsson, L., Weber, H., Alpers, G. W., Arolt, V., Fehm, L., Fydrich, T., Gerlach, A. L., Hamm, A., Kircher, T., Pané-farré, C. A., Pauli, P., Rief, W., Ströhle, A., Plag, J., Lang, T., Wittchen, H., Mattheisen, M., Meier, S., Metspalu, A., Domschke, K., Reif, A., Hovatta, I., Lindefors, N., Andersson, E., Schalling, M., Mbarek, H., Milaneschi, Y., De Geus, E. J. C., Boomsma, D. I., Penninx, B. W. J. H., Thorgeirsson, T. E., Steinberg, S., Stefansson, K., Stefansson, H., Müller-myhsok, B., Hansen, Thomas Folkmann, Børglum, A. D., Werge, Thomas, Mortensen, P. B., Nordentoft, Merete, Hougaard, D. M., Hultman, C. M., Sullivan, P. F., Nöthen, M. M., Woldbye, David Paul Drucker, Mors, O., Binder, E. B., Rück, C., Ripke, S., Deckert, J. & Schumacher, J., 2021, In: Molecular Psychiatry. 26, p. 4179–4190 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Gestational age-dependent development of the neonatal metabolome

    Ernst, M., Rogers, S., Lausten-Thomsen, U., Björkbom, A., Laursen, S. S., Courraud, J., Borglum, A., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Hougaard, D. M. & Cohen, A. S., 2021, In: Pediatric Research. 89, p. 1396–1404 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Identification of genetic loci associated with nocturnal enuresis: a genome-wide association study

    Jørgensen, C. S., Horsdal, H. T., Rajagopal, V. M., Grove, J., Als, T. D., Kamperis, K., Nyegaard, M., Walters, G. B., Eðvarðsson, V. Ö., Stefánsson, H., Nordentoft, M., Hougaard, D. M., Werge, T., Mors, O., Mortensen, P. B., Agerbo, E., Rittig, S., Stefánsson, K., Børglum, A. D., Demontis, D. & 1 others, Christensen, J. H., 2021, In: The Lancet Child & Adolescent Health. 5, 3, p. 201-209

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease

    Herborg, F., Jensen, K. L., Tolstoy, S., Arends, N., Posselt, L. P., Shekar, A., Aguilar, J., Lund, V. K., Erreger, K., Rickhag, M., Lycas, M. D., Lonsdale, M. N., Rahbek-Clemmensen, T., Sorensen, A. T., Newman, A. H., Lokkegaard, A., Kjaerulff, O., Werge, T., Moller, L. B., Matthies, H. J. G. & 4 others, Galli, A., Hjermind, L. E., Gether, Ulrik & IPSYCH Researchers, I. R., 2021, In: JCI insight. 6, 18, 21 p., 151496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life - A Large Prospective Cohort Study on Adult Danes

    Didriksen, Maria, Werge, Thomas, Nissen, J., Schwinn, M., Sørensen, E., Nielsen, K. R., Bruun, M. T., Banasik, Karina, Hansen, T. F., Erikstrup, C., Ostrowski, Sisse Rye, Jennum, Poul, Hjalgrim, Henrik, Ullum, H. & Pedersen, Ole Birger Vesterager, 2021, In: International Journal of Environmental Research and Public Health. 18, 14, 14 p., 7610.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Is the Association between Parents' Mental Illness and Child Psychopathology Mediated via Home Environment and Caregiver's Psychosocial Functioning? A Mediation Analysis of the Danish High Risk and Resilience Study-VIA7, a Population-Based Cohort Study

    Uddin, M. J., Ekstrøm, C. T., Hemager, N., Christiani, C. A. J., Gregersen, M., Ellersgaard, D. V., Spang, K. S., Greve, A., Burton, B. K., Søndergaard, A., Nudel, R., Mortensen, P. B., Pedersen, M. G., Pedersen, C. B., Wang, Y., Werge, T., Bybjerg-Grauholm, J., Von Plessen, K. J., Bliksted, V., Mors, O. & 2 others, Thorup, Anne & Nordentoft, Merete, 2021, In: Schizophrenia Bulletin Open. 2, 1, 12 p., sgab024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

    Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J., 2021, In: American Journal of Human Genetics. 108, 6, p. 1001-1011 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 34394780