Thomas Werge

Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors

Didriksen, Maria, Allen, R. P., Burchell, B. J., Thørner, L. W., Rigas, A. S., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nielsen, K., Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., May 2018, In: Sleep Medicine. 45, p. 124-131 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

Hannon, E., Schendel, D., Ladd-Acosta, C., Grove, J., Hansen, C. S., Andrews, S. V., Hougaard, D. M., Bresnahan, M., Mors, O., Hollegaard, M. V., Bækvad-Hansen, M., Hornig, M., Mortensen, P. B., Børglum, A. D., Werge, T., Pedersen, M. G., Nordentoft, M., Buxbaum, J., Fallin, M. D., Bybjerg-Grauholm, J. & 2 others, Reichenberg, A. & Mill, J., 28 Mar 2018, In: Genome Medicine. 10, 13 p., 19.

Research output: Contribution to journal › Journal article › Research › peer-review

Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register

Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 15 Mar 2018, In: Biological Psychiatry. 83, 6, p. 492-498

Research output: Contribution to journal › Journal article › Research › peer-review

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

Haney, J. R., CommonMind Consortium, C. C., PsychENCODE Consortium, P. C. & iPSYCH-BROAD Working Group, I. W. G., 9 Feb 2018, In: Science. 359, 6376, p. 693-697 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response

Larsen, K. M., Pellegrino, G., Birknow, M. R., Kjær, T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Mørup, M. & Siebner, Hartwig Roman, 2018, In: Schizophrenia Bulletin. 44, 2, p. 388–397

Research output: Contribution to journal › Journal article › Research › peer-review

AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

Nagy, S., Maurer, G. W., Hentze, J. L., Rose, M., Werge, Thomas & Rewitz, Kim, 2018, In: PLOS Genetics. 14, 12, e1007623.

Research output: Contribution to journal › Journal article › Research › peer-review

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties

St Pourcain, B., Robinson, E. B., Anttila, V., Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., Zammit, S., Fisher, S. E., Neale, B. M., Anney, R. J. L., Ripke, S., Hollegaard, M. V., Werge, T., iPSYCH-SSI-Broad Autism Group, Ronald, A., Grove, J., Hougaard, D. M. & 4 others, Børglum, A. D., Mortensen, P. B., Daly, M. J. & Davey Smith, G., 2018, In: Molecular Psychiatry. 23, 2, p. 263-270

Research output: Contribution to journal › Journal article › Research › peer-review

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Haan, L. D., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, Thomas Folkmann, Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Juliá, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'callaghan, E., O'dushlaine, C., O'neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Os, J. V., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, Thomas, Daly, M. J., Sullivan, P. F. & O'donovan, M. C., 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.

Research output: Contribution to journal › Journal article › Research › peer-review

Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Siebner, Hartwig Roman & Garrido, M. I., 2018, In: Schizophrenia Research. 197, p. 328-336

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of shared heritability in common disorders of the brain

Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 557 others, Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Leverenz, J. B., Levey, A. I., Lieberman, A. P., Pankratz, V. S., Poon, W. W., Quinn, J. F., Saykin, A. J., Schneider, L. S., Smith, A. G., Sonnen, J. A., Stern, R. A., Van Deerlin, V. M., Van Eldik, L. J., Harold, D., Russo, G., Rubinsztein, D. C., Bayer, A., Tsolaki, M., Proitsi, P., Fox, N. C., Hampel, H., Owen, M. J., Mead, S., Passmore, P., Morgan, K., Nöthen, M. M., Schott, J. M., Rossor, M., Lupton, M. K., Hoffmann, P., Kornhuber, J., Lawlor, B., Mcquillin, A., Al-Chalabi, A., Bis, J. C., Ruiz, A., Boada, M., Seshadri, S., Beiser, A., Rice, K., Van Der Lee, S. J., De Jager, P. L., Geschwind, D. H., Riemenschneider, M., Riedel-Heller, S., Rotter, J. I., Ransmayr, G., Hyman, B. T., Cruchaga, C., Alegret, M., Winsvold, B., Palta, P., Farh, K., Cuenca-Leon, E., Furlotte, N., Kurth, T., Ligthart, L., Terwindt, G. M., Freilinger, T., Ran, C., Gordon, S. D., Borck, G., Adams, H. H. H., Lehtimäki, T., Wedenoja, J., Buring, J. E., Schürks, M., Hrafnsdottir, M., Hottenga, J., Penninx, B., Artto, V., Kaunisto, M., Vepsäläinen, S., Martin, N. G., Montgomery, G. W., Kurki, M. I., Hämäläinen, E., Huang, H., Huang, J., Sandor, C., Webber, C., Muller-Myhsok, B., Schreiber, S., Salomaa, V., Loehrer, E., Göbel, H., Macaya, A., Pozo-Rosich, P., Hansen, T., Werge, Thomas, Kaprio, J., Metspalu, A., Kubisch, C., Ferrari, M. D., Belin, A. C., Van Den Maagdenberg, A. M. J. M., Zwart, J., Boomsma, D., Eriksson, N., Olesen, Jes, Chasman, D. I., Nyholt, D. R., Anney, R., Avbersek, A., Baum, L., Berkovic, S., Bradfield, J., Buono, R., Catarino, C. B., Cossette, P., De Jonghe, P., Depondt, C., Dlugos, D., Ferraro, T. N., French, J., Hjalgrim, H., Jamnadas-khoda, J., Kälviäinen, R., Kunz, W. S., Lerche, H., Leu, C., Lindhout, D., Lo, W., Lowenstein, D., Mccormack, M., Møller, R. S., Molloy, A., Ng, P., Oliver, K., Privitera, M., Radtke, R., Ruppert, A., Sander, T., Schachter, S., Schankin, C., Scheffer, I., Schoch, S., Sisodiya, S. M., Smith, P., Sperling, M., Striano, P., Surges, R., Thomas, G. N., Visscher, F., Whelan, C. D., Zara, F., Heinzen, E. L., Marson, A., Becker, F., Stroink, H., Zimprich, F., Gasser, T., Gibbs, R., Heutink, P., Martinez, M., Morris, H. R., Sharma, M., Ryten, M., Mok, K. Y., Pulit, S., Bevan, S., Holliday, E., Attia, J., Battey, T., Boncoraglio, G., Thijs, V., Chen, W., Mitchell, B., Rothwell, P., Sharma, P., Sudlow, C., Vicente, A., Markus, H., Kourkoulis, C., Pera, J., Raffeld, M., Silliman, S., Boraska Perica, V., Thornton, L. M., Huckins, L. M., William Rayner, N., Lewis, C. M., Gratacos, M., Rybakowski, F., Keski-Rahkonen, A., Raevuori, A., Hudson, J. I., Reichborn-Kjennerud, T., Monteleone, P., Karwautz, A., Mannik, K., Baker, J. H., O’toole, J. K., Trace, S. E., Davis, O. S. P., Helder, S. G., Ehrlich, S., Herpertz-dahlmann, B., Danner, U. N., Van Elburg, A. A., Clementi, M., Forzan, M., Docampo, E., Lissowska, J., Hauser, J., Tortorella, A., Maj, M., Gonidakis, F., Tziouvas, K., Papezova, H., Yilmaz, Z., Wagner, G., Cohen-woods, S., Herms, S., Julià, A., Rabionet, R., Dick, D. M., Ripatti, S., Andreassen, O. A., Espeseth, T., Lundervold, A. J., Steen, V. M., Pinto, D., Scherer, S. W., Aschauer, H., Schosser, A., Alfredsson, L., Padyukov, L., Halmi, K. A., Mitchell, J., Strober, M., Bergen, A. W., Kaye, W., Szatkiewicz, J. P., Cormand, B., Ramos-quiroga, J. A., Sánchez-mora, C., Ribasés, M., Casas, M., Hervas, A., Arranz, M. J., Haavik, J., Zayats, T., Johansson, S., Williams, N., Elia, J., Dempfle, A., Rothenberger, A., Kuntsi, J., Oades, R. D., Banaschewski, T., Franke, B., Buitelaar, J. K., Arias Vasquez, A., Doyle, A. E., Reif, A., Lesch, K., Freitag, C., Rivero, O., Palmason, H., Romanos, M., Langley, K., Rietschel, M., Witt, S. H., Dalsgaard, S., Børglum, A. D., Waldman, I., Wilmot, B., Molly, N., Bau, C. H. D., Crosbie, J., Schachar, R., Loo, S. K., Mcgough, J. J., Grevet, E. H., Medland, S. E., Robinson, E., Weiss, L. A., Bacchelli, E., Bailey, A., Bal, V., Battaglia, A., Betancur, C., Bolton, P., Cantor, R., Celestino-soper, P., Dawson, G., De Rubeis, S., Duque, F., Green, A., Klauck, S. M., Leboyer, M., Levitt, P., Maestrini, E., Mane, S., De-luca, D. M., Parr, J., Regan, R., Reichenberg, A., Sandin, S., Vorstman, J., Wassink, T., Wijsman, E., Cook, E., Santangelo, S., Delorme, R., Rogé, B., Magalhaes, T., Arking, D., Schulze, T. G., Thompson, R. C., Strohmaier, J., Matthews, K., Melle, I., Morris, D., Blackwood, D., Mcintosh, A., Bergen, S. E., Schalling, M., Jamain, S., Maaser, A., Fischer, S. B., Reinbold, C. S., Fullerton, J. M., Grigoroiu-serbanescu, M., Guzman-parra, J., Mayoral, F., Schofield, P. R., Cichon, S., Mühleisen, T. W., Degenhardt, F., Schumacher, J., Bauer, M., Mitchell, P. B., Gershon, E. S., Rice, J., Potash, J. B., Zandi, P. P., Craddock, N., Ferrier, I. N., Alda, M., Rouleau, G. A., Turecki, G., Ophoff, R., Pato, C., Anjorin, A., Stahl, E., Leber, M., Czerski, P. M., Edenberg, H. J., Cruceanu, C., Jones, I. R., Posthuma, D., Andlauer, T. F. M., Forstner, A. J., Streit, F., Baune, B. T., Air, T., Sinnamon, G., Wray, N. R., Macintyre, D. J., Porteous, D., Homuth, G., Rivera, M., Grove, J., Middeldorp, C. M., Hickie, I., Pergadia, M., Mehta, D., Smit, J. H., Jansen, R., De Geus, E., Dunn, E., Li, Q. S., Nauck, M., Schoevers, R. A., Beekman, A. T., Knowles, J. A., Viktorin, A., Arnold, P., Barr, C. L., Bedoya-berrio, G., Bienvenu, O. J., Brentani, H., Burton, C., Camarena, B., Cappi, C., Cath, D., Cavallini, M., Cusi, D., Darrow, S., Denys, D., Derks, E. M., Dietrich, A., Fernandez, T., Figee, M., Freimer, N., Gerber, G., Grados, M., Greenberg, E., Hanna, G. L., Hartmann, A., Hirschtritt, M. E., Hoekstra, P. J., Huang, A., Huyser, C., Illmann, C., Jenike, M., Kuperman, S., Leventhal, B., Lochner, C., Lyon, G. J., Macciardi, F., Madruga-garrido, M., Malaty, I. A., Maras, A., Mcgrath, L., Miguel, E. C., Mir, P., Nestadt, G., Nicolini, H., Okun, M. S., Pakstis, A., Paschou, P., Piacentini, J., Pittenger, C., Plessen, K., Ramensky, V., Ramos, E. M., Reus, V., Richter, M. A., Riddle, M. A., Robertson, M. M., Roessner, V., Rosário, M., Samuels, J. F., Sandor, P., Stein, D. J., Tsetsos, F., Van Nieuwerburgh, F., Weatherall, S., Wendland, J. R., Wolanczyk, T., Worbe, Y., Zai, G., Goes, F. S., Mclaughlin, N., Nestadt, P. S., Grabe, H., Depienne, C., Konkashbaev, A., Lanzagorta, N., Valencia-duarte, A., Bramon, E., Buccola, N., Cahn, W., Cairns, M., Chong, S. A., Cohen, D., Crespo-facorro, B., Crowley, J., Davidson, M., Delisi, L., Dinan, T., Donohoe, G., Drapeau, E., Duan, J., Haan, L., Hougaard, D., Karachanak-yankova, S., Khrunin, A., Klovins, J., Kučinskas, V., Lee Chee Keong, J., Limborska, S., Loughland, C., Lönnqvist, J., Maher, B., Mattheisen, M., Mcdonald, C., Murphy, K. C., Murray, R., Nenadic, I., Van Os, J., Pantelis, C., Pato, M., Petryshen, T., Quested, D., Roussos, P., Sanders, A. R., Schall, U., Schwab, S. G., Sim, K., So, H., Stögmann, E., Subramaniam, M., Toncheva, D., Waddington, J., Walters, J., Weiser, M., Cheng, W., Cloninger, R., Curtis, D., Gejman, P. V., Henskens, F., Mattingsdal, M., Oh, S., Scott, R., Webb, B., Breen, G., Churchhouse, C., Bulik, C. M., Daly, M., Dichgans, M., Faraone, S. V., Guerreiro, R., Holmans, P., Kendler, K. S., Koeleman, B., Mathews, C. A., Price, A., Scharf, J., Sklar, P., Williams, J., Wood, N. W., Cotsapas, C., Palotie, A., Smoller, J. W., Sullivan, P., Rosand, J., Corvin, A. & Neale, B. M., 2018, In: Science. 360, 6395, 40 p., eaap8757.

Research output: Contribution to journal › Journal article › Research › peer-review

Ancient genomes from Iceland reveal the making of a human population

Ebenesersdóttir, S. S., Sandoval Velasco, M., Gunnarsdóttir, E. D., Jagadeesan, A., Guðmundsdóttir, V. B., Thordardóttir, E. L., Einarsdóttir, M. S., Moore, K. H. S., Sigurðsson, Á., Magnusdóttir, D. N., Jonsson, H., Snorradóttir, S., Hovig, E., Møller, P., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T., Cavalleri, G. L. & 10 others, Gilbert, E., Lalueza-Fox, C., Walser, J. ,. I., Kristjánsdóttir, S., Gopalakrishnan, Shyam, Árnadóttir, L., Magnússon, Ó. Þ., Gilbert, M Thomas P, Stefánsson, K. & Helgason, A., 2018, In: Science. 360, 6392, p. 1028-1032 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

LaBianca, S., Pagsberg, Anne Katrine, Jakobsen, K. D., Demur, A. B., Bartalan, M., LaBianca, J. & Werge, Thomas, 2018, In: Journal of Autism and Developmental Disorders. 48, 10, p. 3629-3636 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., Carrera, N., Legge, S. E., Bishop, S., Cameron, D., Hamshere, M. L., Han, J., Hubbard, L., Lynham, A., Mantripragada, K., Rees, E., MacCabe, J. H., McCarroll, S. A., Baune, B. T., Breen, G., Byrne, E. M. & 51 others, Dannlowski, U., Eley, T. C., Hayward, C., Martin, N. G., McIntosh, A. M., Plomin, R., Porteous, D. J., Wray, N. R., Caballero, A., Geschwind, D. H., Huckins, L. M., Ruderfer, D. M., Santiago, E., Sklar, P., Stahl, E. A., Won, H., Agerbo, E., Als, T. D., Andreassen, O. A., Bækvad-Hansen, M., Mortensen, P. B., Pedersen, C. B., Børglum, A. D., Bybjerg-Grauholm, J., Djurovic, S., Durmishi, N., Pedersen, M. G., Golimbet, V., Grove, J., Hougaard, D. M., Mattheisen, M., Molden, E., Mors, O., Nordentoft, Merete, Pejovic-Milovancevic, M., Sigurdsson, E., Silagadze, T., Hansen, C. S., Stefansson, K., Stefansson, H., Steinberg, S., Tosato, S., Werge, Thomas, GERAD1 Consortium:, G. C., CRESTAR Consortium, C. C., Collier, D. A., Rujescu, D., Kirov, G., Owen, M. J., O'Donovan, M. C. & Walters, J. T. R., 2018, In: Nature Genetics. 50, p. 381-389

Research output: Contribution to journal › Journal article › Research › peer-review

Comorbidity of migraine with ADHD in adults

Hansen, Thomas Folkmann, Hoeffding, L. K., Kogelman, L., Haspang, T. M., Ullum, H., Sørensen, E., Erikstrup, C., Pedersen, O. B., Nielsen, K. R., Hjalgrim, H., Paarup, H. M., Werge, Thomas & Burgdorf, K., 2018, In: BMC Neurology. 18, 1, p. 1-9 147.

Research output: Contribution to journal › Journal article › Research › peer-review

Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder

Hughes, T., Sønderby, I. E., Polushina, T., Hansson, L., Holmgren, A., Athanasiu, L., Melbø-Jørgensen, C., Hassani, S., Hoeffding, L. K., Herms, S., Bergen, S. E., Karlsson, R., Song, J., Rietschel, M., Nöthen, M. M., Forstner, A. J., Hoffmann, P., Hultman, C. M., Landén, M., Cichon, S. & 4 others, Werge, Thomas, Andreassen, O. A., Le Hellard, S. & Djurovic, S., 2018, In: Translational Psychiatry. 8, 1, p. 1-12 210.

Research output: Contribution to journal › Journal article › Research › peer-review

GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS. O4.6.

Benros, Michael Eriksen, Nudel, R., Wang, Y., Appadurai, V., Schork, A., Agerbo, E., Werge, Thomas, Nordentoft, Merete, Mortensen, P., Buil, A. & Thompson, W., 2018, In: Schizophrenia Bulletin. 44, Suppl. 1, p. S85 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis

Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I., Buxbaum, J., iPSYCH-Broad ASD Group, the IMAGEN consortium, Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Burke Quinlan, E., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M. L. & 31 others, Artiges, E., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Hohmann, S., Fröhner, J. H., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Reichenberg, A., Børglum, A. D., Grove, J., Mattheisen, M., Werge, Thomas, Mortensen, P. B., Pedersen, M. G., Pedersen, C. B., Mors, O., Nordentoft, Merete, Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., Daly, M. J., Neale, B. M., Robinson, E. B., Cerrato, F., Dumont, A. & Goldstein, J., 2018, In: Translational Psychiatry. 8, 1, 204.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic risk scores and family history as predictors of schizophrenia in Nordic registers

Lu, Y., Pouget, J. G., Andreassen, O. A., Djurovic, S., Esko, T., Hultman, C. M., Metspalu, A., Milani, L., Werge, Thomas & Sullivan, P. F., 2018, In: Psychological Medicine. 48, 7, p. 1201-1208 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, T. M. D. D. W. G. O. T. P. G. C., 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C., Thomson, P. A., Porteous, D., Campbell, A., Smith, B. H., Black, C., Padmanabhan, S., McIntosh, A. M., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M. & 32 others, Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Hansen, C. S., Hansen, Thomas Folkmann, Krogh, J., Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete & Werge, Thomas, 2018, In: PLOS ONE. 13, 12, p. 1-29 e0209160.

Research output: Contribution to journal › Journal article › Research › peer-review

Molecular genetic overlap between migraine and major depressive disorder

Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, Pers, Tune H, Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas & Olesen, Jes, 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study

Olsen, L., Sparsø, T., Weinsheimer, S. M., Dos Santos, M. B. Q., Mazin, W., Rosengren, A., Sanchez, X. C., Hoeffding, L. K., Schmock, H., Baekvad-Hansen, M., Bybjerg-Grauholm, J., Daly, M. J., Neale, B. M., Pedersen, M. G., Agerbo, E., Mors, O., Børglum, A., Nordentoft, M., Hougaard, D. M., Mortensen, P. B. & 4 others, Geschwind, D. H., Pedersen, C., Thompson, W. K. & Werge, Thomas, 2018, In: The Lancet Psychiatry. 5, 7, p. 573-580 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

Ganna, A., Satterstrom, F. K., Zekavat, S. M., Das, I., Kurki, M. I., Churchhouse, C., Alfoldi, J., Martin, A. R., Havulinna, A. S., Byrnes, A., Thompson, W. K., Nielsen, P. R., Karczewski, K. J., Saarentaus, E., Rivas, M. A., Gupta, N., Pietiläinen, O., Emdin, C. A., Lescai, F., Bybjerg-Grauholm, J. & 28 others, Flannick, J., GoT2D/T2D-GENES Consortium, G. C., Mercader, J. M., Udler, M., SIGMA Consortium Helmsley IBD Exome Sequencing Project, S. C. H. I. E. S. P., FinMetSeq Consortium, F. C., iPSYCH-Broad Consortium, I. C., Laakso, M., Salomaa, V., Hultman, C., Ripatti, S., Hämäläinen, E., Moilanen, J. S., Körkkö, J., Kuismin, O., Nordentoft, Merete, Hougaard, D. M., Mors, O., Werge, Thomas, Mortensen, P. B., MacArthur, D., Daly, M. J., Sullivan, P. F., Locke, A. E., Palotie, A., Børglum, A. D., Kathiresan, S. & Neale, B. M., 2018, In: American Journal of Human Genetics. 102, 6, p. 1204-1211

Research output: Contribution to journal › Journal article › Research › peer-review

Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Fan, C. C., McGrath, J. J., Appadurai, V., Buil, A., Gandal, M. J., Schork, A. J., Mortensen, P. B., Agerbo, E., Geschwind, S. A., Geschwind, D., Werge, Thomas, Thompson, W. K. & Pedersen, C. B., 2018, In: Nature Communications. 9, 7 p., 5296.

Research output: Contribution to journal › Journal article › Research › peer-review

The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods

Thornton, L. M., Munn-Chernoff, M. A., Baker, J. H., Juréus, A., Parker, R., Henders, A. K., Larsen, J. T., Petersen, L., Watson, H. J., Yilmaz, Z., Kirk, K. M., Gordon, S., Leppä, V. M., Martin, F. C., Whiteman, D. C., Olsen, C. M., Werge, T. M., Pedersen, N. L., Kaye, W., Bergen, A. W. & 26 others, Halmi, K. A., Strober, M., Kaplan, A. S., Woodside, D. B., Mitchell, J., Johnson, C. L., Brandt, H., Crawford, S., Horwood, L. J., Boden, J. M., Pearson, J. F., Duncan, L. E., Grove, J., Mattheisen, M., Jordan, J., Kennedy, M. A., Birgegård, A., Lichtenstein, P., Norring, C., Wade, T. D., Montgomery, G. W., Martin, N. G., Landén, M., Mortensen, P. B., Sullivan, P. F. & Bulik, C. M., 2018, In: Contemporary Clinical Trials. 74, p. 61-69 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders

Pedersen, C. B., Bybjerg-Grauholm, J., Pedersen, M. G., Grove, J., Agerbo, E., Bækvad-Hansen, M., Poulsen, J. B., Hansen, C. S., McGrath, J. J., Als, T. D., Goldstein, J. I., Neale, B. M., Daly, M. J., Hougaard, D. M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Mortensen, P. B., 2018, In: Molecular Psychiatry. 23, p. 6-14 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A. & 31 others, Van Der Auwera, S., Wray, N. R., Boomsma, D. I., Penninx, B. W. J. H., CHARGE InflammationWorking Group and the Major Depressive DisorderWorking Group of the Psychiatric Genomics Consortium, C. I. G. A. T. M. D. D. G. O. T. P. G. C., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bakvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschon, H. N., Bybjerg-Grauholm, J., Cai, N., Hansen, C. S., Hansen, T. F., Krogh, J., Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete & Werge, Thomas, Dec 2017, In: JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission

Nielsen, J., Fejgin, K., Sotty, F., Nielsen, V., Mørk, A., Christoffersen, C. T., Yavich, L., Lauridsen, J. B., Clausen, D., Larsen, P. H., Egebjerg, J., Werge, Thomas, Kallunki, P., Christensen, K. V. & Didriksen, M., 30 Nov 2017, In: Translational Psychiatry. 7, 12 p., 1261.

Research output: Contribution to journal › Journal article › Research › peer-review

Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome

Starnawska, A., Hansen, C. S., Sparsø, T., Mazin, W., Olsen, L., Bertalan, M., Buil, A., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mortensen, P. B., Pedersen, C. B., Nyegaard, M., Werge, Thomas & Weinsheimer, S., 29 Aug 2017, In: Translational Psychiatry. 7, 11 p., e1221.

Research output: Contribution to journal › Journal article › Research › peer-review

Prevalence of restless legs syndrome and associated factors in an otherwise healthy population: results from the Danish Blood Donor Study

Didriksen, M., Rigas, A. S., Allen, R. P., Burchell, B. J., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., Aug 2017, In: Sleep Medicine. 36, p. 55-61 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Quetiapine extended release versus aripiprazole in children and adolescents with first-episode psychosis: the multicentre, double-blind, randomised tolerability and efficacy of antipsychotics (TEA) trial

Pagsberg, A. K., Jeppesen, P., Klauber, D. G., Jensen, K. G., Ruda, D., Stentebjerg-Olesen, M., Jantzen, P., Rasmussen, S., Saldeen, E. A-S., Lauritsen, M-B. G., Bilenberg, N., Stenstrom, A. D., Nyvang, L., Madsen, S., Werge, T. M., Lange, T., Gluud, C., Skoog, M., Winkel, P., Jepsen, J. R. M. & 3 others, Fagerlund, Birgitte, Correll, C. U. & Fink-Jensen, Anders, Aug 2017, In: The Lancet Psychiatry. 4, 8, p. 605-618

Research output: Contribution to journal › Journal article › Research › peer-review

Lessons to be learned from 22q2.11 syndromes: reply

Hoeffding, L. K., Pedersen, C. B. & Werge, Thomas, Jul 2017, In: JAMA Psychiatry. 74, 7, p. 757-758 2 p.

Research output: Contribution to journal › Comment/debate › Research

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

Weiner, D. J., Wigdor, E. M., Ripke, S., Walters, R. K., Kosmicki, J. A., Grove, J., Samocha, K. E., Goldstein, J. I., Okbay, A., Bybjerg-Grauholm, J., Werge, T., Hougaard, D. M., Taylor, J., Skuse, D., Devlin, B., Anney, R., Sanders, S. J., Bishop, S., Mortensen, P. B., Børglum, A. D. & 32 others, Smith, G. D., Daly, M. J., Robinson, E. B., Bækvad-Hansen, M., Dumont, A., Hansen, C., Hansen, T. F., Howrigan, D., Mattheisen, M., Moran, J., Mors, O., Nordentoft, Merete, Nørgaard-Pedersen, B., Poterba, T., Poulsen, J., Stevens, C., Anttila, V., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Wassink, T. H., Psychiatric Genomics Consortium Autism Group, P. G. C. A. G. & iPSYCH-Broad Autism Group, I. A. G., Jul 2017, In: Nature Genetics. 49, 7, p. 978-985 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

Sapkota, Y., Steinthorsdottir, V., Morris, A. P., Fassbender, A., Rahmioglu, N., De Vivo, I., Buring, J. E., Zhang, F., Edwards, T. L., Jones, S., Dorien, O., Peterse, D., Rexrode, K. M., Ridker, P. M., Schork, A. J., MacGregor, S., Martin, N. G., Becker, C. M., Adachi, S., Yoshihara, K. & 23 others, Enomoto, T., Takahashi, A., Kamatani, Y., Matsuda, K., Kubo, M., Thorleifsson, G., Geirsson, R. T., Thorsteinsdottir, U., Wallace, L. M., Werge, Thomas, Thompson, W. K., Yang, J., Velez Edwards, D. R., Nyegaard, M., Low, S. K., Zondervan, K. T., Missmer, S. A., D'Hooghe, T., Montgomery, G. W., Chasman, D. I., Stefansson, K., Tung, J. Y. & Nyholt, D. R., 24 May 2017, In: Nature Communications. 8, 12 p., 15539.

Research output: Contribution to journal › Journal article › Research › peer-review

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

Anney, R. J. L., Ripke, S., Anttila, V., Grove, J., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Robinson, E., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Werge, T., Wassink, T. H., Waltes, R. & 143 others, Walsh, C. A., Wallace, S., Vorstman, J. A. S., Vieland, V. J., Vicente, A. M., Vanengeland, H., Tsang, K., Thompson, A. P., Szatmari, P., Svantesson, O., Steinberg, S., Stefansson, K., Stefansson, H., State, M. W., Soorya, L., Silagadze, T., Scherer, S. W., Schellenberg, G. D., Sandin, S., Sanders, S. J., Saemundsen, E., Rouleau, G. A., Rogé, B., Roeder, K., Roberts, W., Reichert, J., Reichenberg, A., Rehnström, K., Regan, R., Poustka, F., Poultney, C. S., Piven, J., Pinto, D., Pericak-Vance, M. A., Pejovic-Milovancevic, M., Pedersen, M. G., Pedersen, C. B., Paterson, A. D., Parr, J. R., Pagnamenta, A. T., Oliveira, G., Nurnberger, J. I., Nordentoft, Merete, Murtha, M. T., Mouga, S., Mortensen, P. B., Mors, O., Morrow, E. M., Moreno-De-Luca, D., Monaco, A. P., Minshew, N., Merikangas, A., McMahon, W. M., McGrew, S. G., Mattheisen, M., Martsenkovsky, I., Martin, D. M., Mane, S. M., Magnusson, P., Magalhaes, T., Maestrini, E., Lowe, J. K., Lord, C., Levitt, P., Martin, C. L., Ledbetter, D. H., Leboyer, M., Lecouteur, A. S., Ladd-Acosta, C., Kolevzon, A., Klauck, S. M., Jacob, S., Iliadou, B., Hultman, C. M., Hougaard, D. M., Hertz-Picciotto, I., Hendren, R., Hansen, C. S., Haines, J. L., Guter, S. J., Grice, D. E., Green, J. M., Green, A., Goldberg, A. P., Gillberg, C., Gilbert, J., Gallagher, L., Freitag, C. M., Fombonne, E., Folstein, S. E., Fernandez, B., Fallin, M. D., Ercan-Sencicek, A. G., Ennis, S., Duque, F., Duketis, E., Delorme, R., Derubeis, S., Dejonge, M. V., Dawson, G., Cuccaro, M. L., Correia, C. T., Conroy, J., Conceição, I. C., Chiocchetti, A. G., Celestino-Soper, P. B. S., Casey, J., Cantor, R. M., Café, C., Bybjerg-Grauholm, J., Brennan, S., Bourgeron, T., Bolton, P. F., Bölte, S., Bolshakova, N., Betancur, C., Bernier, R., Beaudet, A. L., Battaglia, A., Bal, V. H., Baird, G., Bailey, A. J., Bækvad-Hansen, M., Bader, J. S., Bacchelli, E., Anagnostou, E., Amaral, D., Almeida, J., Børglum, A. D., Buxbaum, J. D., Chakravarti, A., Cook, E. H., Coon, H., Geschwind, D. H., Gill, M., Hakonarson, H., Hallmayer, J., Palotie, A., Santangelo, S., Sutcliffe, J. S., Arking, D. E., Devlin, B. & Daly, M. J., 22 May 2017, In: Molecular Autism. 8, 17 p., 21.

Research output: Contribution to journal › Journal article › Research › peer-review

Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register

Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, Apr 2017, In: EBioMedicine. 18, p. 320-326

Research output: Contribution to journal › Journal article › Research › peer-review

Risk of psychiatric disorders among individuals with the 22q11.2 deletion or duplication: A Danish nationwide, register-based study

Hoeffding, L. K., Trabjerg, B. B., Olsen, L., Mazin, W., Sparsø, T., Vangkilde, A., Mortensen, P. B., Pedersen, C. B. & Werge, Thomas, 1 Mar 2017, In: JAMA Psychiatry. 74, 3, p. 282-290 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Nomenclature for alleles of the human carboxylesterase 1 gene

INDICES Consortium, I. C., 1 Jan 2017, In: Pharmacogenetics and Genomics. 27, 2, p. 78-80 3 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry

Schork, A. J., iPSYCH-SSI-Broad Group, I. G. & Werge, Thomas, 2017, In: Scientific Reports. 7, 11 p., 11380.

Research output: Contribution to journal › Journal article › Research › peer-review

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C. & 86 others, van der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, Thomas, Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z., 2017, In: Nature Communications. 8, 11 p., 744.

Research output: Contribution to journal › Journal article › Research › peer-review

Comorbidities to restless legs syndrome – results from the Danish blood donor study

Didriksen, Maria, Hansen, T., Rigas, A., Allen, R., Burchell, B., Thørner, L., Nielsen, K., Di Angelantonio, E., Nielsen, M., Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, O., Paarup, H., Hjalgrim, H., Bruun, M., Burgdorf, K., Sørensen, E. & Ullum, H., 2017, In: Sleep Medicine. 40, Supplement 1, p. E79 1 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., Gujral, M., Brandler, W. M., Malhotra, D., Wang, Z., Fuentes Fajarado, K. V., Maile, M. S., Ripke, S., Agartz, I., Albus, M., Alexander, M. & 34 others, Amin, F., Atkins, J., Bacanu, S. A., Belliveau, R. A., Bergen, S. E., Bertalan, M., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Bulik-Sullivan, B., Byerley, W., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Cheng, W., Hansen, M., Hansen, T., Olsen, L., Pers, T. H., Rasmussen, H. B., Werge, Thomas, Scherer, S. W., Neale, B. M., Sebat, J. & CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, C. A. S. W. G. O. T. P. G. C., 2017, In: Nature Genetics. 49, 1, p. 27-35

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluation of shared genetic susceptibility loci between autoimmune diseases and schizophrenia based on genome-wide association studies

Hoeffding, L. K. E., Rosengren, A., Thygesen, J. H., Schmock, H., Werge, Thomas & Hansen, T., 2017, In: Nordic Journal of Psychiatry. 71, 1, p. 20-25 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C. & 31 others, Sproviero, W., Jones, A. R., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Bauer, D., Kahlke, T., Williams, K., Eftimov, F., Fogh, I., Ticozzi, N., Lin, K., Millecamps, S., Salachas, F., Meininger, V., Carvalho, M. D., Pinto, S., Mora, J. S., Rojas-Garcyá, R., Polak, M., Chandran, S., Andersen, P. M., Pers, Tune H, Hansen, M., Hansen, T., Li, T., Olsen, L., Rasmussen, H. B., Werge, Thomas & Project MinE GWAS Consortium & Schizophrenia Working Group of the Psychiatric Genomics Consortium, P. M. G. C. &. S. W. G. O. T. P. G. C., 2017, In: Nature Communications. 8, 14774.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 34 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A., Hottenga, J., Hougaard, D. M., Werge, Thomas, Esko, T., Kutalik, Z., Wilson, J. F. & et al., E. A., 2017, In: Nature Communications. 8, 13 p., 910.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment

Le Hellard, S., Wang, Y., Witoelar, A., Zuber, V., Bettella, F., Hugdahl, K., Espeseth, T., Steen, V. M., Melle, I., Desikan, R., Schork, A. J., Thompson, W. K., Dale, A. M., Djurovic, S., Andreassen, O. A., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Ripke, S., Neale, B. M., Corvin, A., Pers, T. H. & 11 others, Agerbo, E., Demontis, D., Hansen, T., Hollegaard, M. V., Hougaard, D. M., Mors, O., Børglum, A. D., Werge, Thomas, Daly, M. J., Sullivan, P. F. & O'Donovan, M. C., 2017, In: Schizophrenia Bulletin. 43, 3, p. 654-664

Research output: Contribution to journal › Journal article › Research › peer-review

Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility?

Hilker, R., Helenius, D., Fagerlund, B., Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 2017, In: EBioMedicine. 18, p. 320-326

Research output: Contribution to journal › Journal article › Research › peer-review

Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: A study in male mice

Didriksen, M., Fejgin, K., Nilsson, S. R. O., Birknow, M. R., Grayton, H. M., Larsen, P. H., Lauridsen, J. B., Nielsen, V., Celada, P., Santana, N., Kallunki, P., Christensen, K. V., Werge, Thomas, Stensbøl, T. B., Egebjerg, J., Gastambide, F., Artigas, F., Bastlund, J. F. & Nielsen, J., 2017, In: Journal of Psychiatry and Neuroscience. 42, 1, p. 48-58 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Severe Parkinsonism and Creatine Kinase Increase After Low-Dose Aripiprazole Treatment in a Patient of African Descent

Jørgensen, A., Thorleifsson, A., Jimenez-Solem, E., Werge, Thomas & Rasmussen, H. B., 2017, In: Journal of Clinical Psychopharmacology. 37, 5, p. 630-631

Research output: Contribution to journal › Letter › Research › peer-review

The catechol-O-methyltransferase (COMT) Val158Met genotype modulates working memory-related dorsolateral prefrontal response and performance in bipolar disorder

Miskowiak, K. W., Kjærstad, H. L., Støttrup, M. M., Svendsen, A. M., Demant, K. M., Hoeffding, L. K., Werge, Thomas, Burdick, K. E., Domschke, K., Carvalho, A. F., Vieta, E., Vinberg, Maj, Kessing, Lars Vedel, Siebner, Hartwig Roman & Macoveanu, J., 2017, In: Bipolar Disorders. 19, 3, p. 214-224 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Investigation of SNP rs2060546 Immediately Upstream to NTN4 in a Danish Gilles de la Tourette Syndrome Cohort

Padmanabhuni, S. S., Houssari, R., Esserlind, A., Olesen, Jes, Werge, Thomas, Hansen, T. F., Bertelsen, B., Tsetsos, F., Paschou, P. & Tümer, Asuman Zeynep, Nov 2016, In: Frontiers in Neuroscience. 10, 7 p., 531.

Research output: Contribution to journal › Journal article › Research › peer-review

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A. D., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D. W., Mowry, B. J., Müller-Mhysok, B., Neale, B. M. & 297 others, Nenadic, I., Nöthen, M. M., O’Dushlaine, C., Rietschel, M., Ruderfer, D. M., Rujescu, D., Schulze, T. G., Simonson, M. A., Stahl, E. A., Strohmaier, J., Witt, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K., Holmans, P. A., Lee, P. H., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, Tune H, Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W. F., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Robert Cloninger, C., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Del-Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Gratten, J., de Haan, L., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Julià, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Chee Keong, J. L., Hong Lee, S., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Mallet, J., Marsal, S., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S. M., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'Callaghan, E., O'Dushlaine, C. T., Anthony O'Neill, F., Oh, S. Y., Olincy, A., Olsen, L., van Os, J., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A. L., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, Henrik Berg, Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Scott Stroup, T., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Watts-Williams, S. J., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Wray, N. R., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Riley, B. P., Sham, P., Sklar, P., St Clair, D., Weinberger, D. R., Wendland, J. R., Werge, Thomas, Daly, M. J., O'Donovan, M. C., Sullivan, P. F. & Keller, M. C., Oct 2016, In: PLOS Genetics. 12, 10, 20 p., e1006343.

Research output: Contribution to journal › Journal article › Research › peer-review

The effect of COMT Val158Met genotype on neural response and performance during spatial working memory in remitted patients with bipolar disorder

Miskowiak, Kamilla, Kjærstad, H. L., Støttrup, M. M., Vinberg, Maj, Carvalho, A. F., Vieta, E., Høffding, L. K., Werge, Thomas, Kessing, Lars Vedel & Macoveanu, J., Oct 2016, In: European Neuropsychopharmacology. 26, Supplement 2, p. S440-S440 1 p., P.2.d.035.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Genetic Markers of Human Evolution Are Enriched in Schizophrenia

Srinivasan, S., Bettella, F., Mattingsdal, M., Wang, Y., Witoelar, A., Schork, A. J., Thompson, W. K., Zuber, V., Winsvold, B. S., Zwart, J., Collier, D. A., Desikan, R. S., Melle, I., Werge, Thomas, Dale, A. M., Djurovic, S., Andreassen, O. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, S. W. G. O. T. P. G. C. T. I. H. G. C., 15 Aug 2016, In: Biological Psychiatry. 80, 4, p. 284-92 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H. & 31 others, Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes & International Headache Genetics Consortium, I. H. G. C., Aug 2016, In: Nature Genetics. 48, 8, p. 856-66 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Digital questionnaire platform in the Danish Blood Donor Study

Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The influence of genetic constitution on migraine drug responses

Christensen, A. F., Esserlind, A., Werge, Thomas, Stefánsson, H., Stefánsson, K. & Olesen, Jes, Jun 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 624-39 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders

Isles, A. R., Ingason, A., Lowther, C., Walters, J. T. R., Gawlick, M., Stöber, G., Rees, E., Martin, J., Little, R. B., Potter, H., Georgieva, L., Pizzo, L., Ozaki, N., Aleksic, B., Kushima, I., Ikeda, M., Iwata, N., Levinson, D. F., Gejman, P. V., Shi, J. & 20 others, Sanders, A. R., Duan, J., Willis, J., Sisodiya, S. M., Costain, G., Werge, Thomas, Degenhardt, F., Giegling, I., Rujescu, D., Hreidarsson, S. J., Saemundsen, E., Ahn, J. W., Ogilvie, C. M., Girirajan, S. D., Stefansson, H., Stefansson, K., O'Donovan, M. C., Owen, M. J., Bassett, A. & Kirov, G., May 2016, In: P L o S Genetics. 12, 5, e1005993.

Research output: Contribution to journal › Journal article › Research › peer-review

Schizophrenia Spectrum Disorders in a Danish 22q11.2 Deletion Syndrome Cohort Compared to the Total Danish Population—A Nationwide Register Study

Vangkilde, A., Olsen, L., Hoeffding, L. K. E., Pedersen, C. B., Mortensen, P. B., Werge, Thomas & Trabjerg, B., May 2016, In: Schizophrenia Bulletin. 42, 3, p. 824-31 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of AADAC Deletion and Gilles de la Tourette Syndrome in a Large European Cohort

Bertelsen, B., Stefánsson, H., Riff Jensen, L., Melchior, L., Debes, N. M., Groth, C., Skov, L., Werge, T., Karagiannidis, I., Tarnok, Z., Barta, C., Nagy, P., Farkas, L., Brøndum-Nielsen, K., Rizzo, R., Gulisano, M., Rujescu, D., Kiemeney, L. A., Tosato, S., Nawaz, M. S. & 14 others, Ingason, A., Unnsteinsdottir, U., Steinberg, S., Ludvigsson, P., Stefansson, K., Kuss, A. W., Paschou, P., Cath, D., Hoekstra, P. J., Müller-Vahl, K., Stuhrmann, M., Silahtaroglu, Asli, Pfundt, R. & Tümer, Z., 1 Mar 2016, In: Biological Psychiatry. 79, 5, p. 383–391 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

Forsingdal, A., Fejgin, K., Nielsen, V., Werge, Thomas & Nielsen, J., 2016, In: Translational Psychiatry. 6, 7, p. 1-9 9 p., e860.

Research output: Contribution to journal › Journal article › Research › peer-review

An epigenetic clock for gestational age at birth based on blood methylation data

Knight, A. K., Craig, J. M., Theda, C., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Hollegaard, M. V., Hougaard, D. M., Mortensen, P. B., Weinsheimer, S. M., Werge, T. M., Brennan, P. A., Cubells, J. F., Newport, D. J., Stowe, Z. N., Cheong, J. L. Y., Dalach, P., Doyle, L. W., Loke, Y. J., Baccarelli, A. A. & 27 others, Just, A. C., Wright, R. O., Téllez-rojo, M. M., Svensson, K., Trevisi, L., Kennedy, E. M., Binder, E. B., Iurato, S., Czamara, D., Räikkönen, K., Lahti, J. M. T., Pesonen, A., Kajantie, E., Villa, P. M., Laivuori, H., Hämäläinen, E., Park, H. J., Bailey, L. B., Parets, S. E., Kilaru, V., Menon, R., Horvath, S., Bush, N. R., Lewinn, K. Z., Tylavsky, F. A., Conneely, K. N. & Smith, A. K., 2016, In: Genome Biology (Online Edition). 17, 11 p., 206.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome

Vangkilde, A., Jepsen, J. M. R., Schmock, H., Olesen, C., Arnarsdóttir, S., Baaré, W. F. C., Plessen, K. J., Didriksen, M., Siebner, Hartwig Roman, Werge, Thomas & Olsen, L., 2016, In: Journal of Neurodevelopmental Disorders. 8, 13 p., 42.

Research output: Contribution to journal › Journal article › Research › peer-review

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

Holland, D., Wang, Y., Thompson, W. K., Schork, A. J., Chen, C., Lo, M., Witoelar, A., Werge, Thomas, O'Donovan, M. C., Andreassen, O. A., Dale, A. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 2016, In: Frontiers in Genetics. 7, 13 p., 15.

Research output: Contribution to journal › Journal article › Research › peer-review

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women

Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., LifeLines Cohort Study, L. C. S., TwinsUK, T. & Werge, Thomas, 2016, In: J A M A Psychiatry. 73, 5, p. 497-505 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., Grove, J., Maller, J., Samocha, K. E., Sanders, J-S. F., Ripke, S., Martin, J., Hollegaard, M. V., Werge, T., Hougaard, D. M., Neale, B. M., Evans, D. M., Skuse, D., Mortensen, P. B., Børglum, A. D., Ronald, A. & 3 others, Smith, G. D., Daly, M. J. & iPSYCH-SSI-Broad Autism Group, I. A. G., 2016, In: Nature Genetics. 48, 5, p. 552-5 4 p.

Research output: Contribution to journal › Letter › Research › peer-review

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Bigdeli, T. B., Ripke, S., Bacanu, S-A., Lee, S. H., Wray, N. R., Gejman, P. V., Rietschel, M., Cichon, S., St Clair, D., Corvin, A., Kirov, G., McQuillin, A., Gurling, H., Rujescu, D., Andreassen, O. A., Werge, T., Blackwood, D. H. R., Pato, C. N., Pato, M. T., Malhotra, A. K. & 4 others, O'Donovan, M. C., Kendler, K. S., Fanous, A. H. & and Schizophrenia Working Group of the Psychiatric Genomics Consortium, A. S. W. G. O. T. P. G. C., 2016, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 171, 2, p. 276-289 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

High loading of polygenic risk in cases with chronic schizophrenia

Meier, S. M., Agerbo, E., Maier, R., Pedersen, C. B., Lang, M., Grove, J., Hollegaard, M. V., Demontis, D., Trabjerg, B. B., Hjorthøj, C., Ripke, S., Degenhardt, F., Nöthen, M. M., Rujescu, D., Maier, W., Werge, T., Mors, O., Hougaard, D. M., Børglum, A. D., Wray, N. R. & 5 others, Rietschel, M., Nordentoft, Merete, Mortensen, P. B., Mattheisen, M. & MooDS SCZ Consortium, M. S. C., 2016, In: Molecular Psychiatry. 21, p. 969-974

Research output: Contribution to journal › Journal article › Research › peer-review

High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA

Poulsen, J. B., Lescai, F., Grove, J., Bækvad-Hansen, M., Christiansen, M., Hagen, C. M., Maller, J., Stevens, C., Li, S., Li, Q., Sun, J., Wang, J., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Børglum, A. D., Daly, M., Hougaard, D. M., Bybjerg-Grauholm, J. & Hollegaard, M. V., 2016, In: P L o S One. 11, 4, 13 p., e0153253.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders

Hoeffding, L. K. E., Duong, L. T. T., Ingason, A., Rosengren, A., Sorbanski, E., Witt, S. H., Djurovic, S., Andreassen, O. A., Hansen, T., Werge, Thomas & Rasmussen, Henrik Berg, 2016, In: Nordic Journal of Psychiatry. 70, 4, p. 276-279 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

Wang, Y., Thompson, W. K., Schork, A. J., Holland, D., Chen, C-H., Bettella, F., Desikan, R. S., Li, W., Witoelar, A., Zuber, V., Devor, A., Nöthen, M. M., Rietschel, M., Chen, Q., Werge, T., Cichon, S., Weinberger, D. R., Djurovic, S., O'Donovan, M. C., Visscher, P. M. & 2 others, Andreassen, O. A. & Dale, A. M., 2016, In: P L o S Genetics. 12, 1, 22 p., e1005803.

Research output: Contribution to journal › Journal article › Research › peer-review

The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample

Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

Thompson, W. K., Wang, Y., Schork, A. J., Witoelar, A., Zuber, V., Xu, S., Werge, Thomas, Holland, D., Andreassen, O. A. & Dale, A. M., 29 Dec 2015, In: P L o S Genetics. 11, 12, p. 1-21 21 p., e1005717.

Research output: Contribution to journal › Journal article › Research › peer-review

Association Study of CHRNA₇ Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study

Bertelsen, B., Oranje, B., Melchior, L., Fagerlund, Birgitte, Werge, Thomas, Mikkelsen, Jens D., Tümer, Asuman Zeynep & Glenthøj, Birte Yding, Dec 2015, In: NeuroMolecular Medicine. 17, 4, p. 423-30 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Linkage and whole genome sequencing identify a locus on 6q25-26 for formal thought disorder and implicate MEF2A regulation

Thygesen, J. H., Zambach, S. K., Ingason, A., Lundin, P., Hansen, T., Bertalan, M., Rosengren, A., Bjerre, D., Ferrero-Miliani, L., Rasmussen, Henrik Berg, Parnas, Josef & Werge, Thomas, Dec 2015, In: Schizophrenia Research. 169, 1-3, p. 441-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family

Duong, L. T. T., Hoeffding, L. K., Petersen, K. B., Knudsen, C. D., Thygesen, J. H., Klitten, L. L., Tommerup, Niels, Ingason, A. & Werge, Thomas, Dec 2015, In: European Journal of Medical Genetics. 58, 12, p. 650-653 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Population genetic differentiation of height and body mass index across Europe

Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., Powell, J. E., Vinkhuyzen, A., Berndt, S. I., Gustafsson, S., Justice, A. E., Kahali, B., Locke, A. E., Pers, T. H., Vedantam, S., Wood, A. R., van Rheenen, W., Andreassen, O. A., Gasparini, P., Metspalu, A. & 23 others, Berg, L. H. V. D., Veldink, J. H., Rivadeneira, F., Werge, Thomas, Abecasis, G. R., Boomsma, D. I., Chasman, D. I., de Geus, E. J. C., Frayling, T. M., Hirschhorn, J. N., Hottenga, J. J., Ingelsson, E., Loos, R. J. F., Magnusson, P. K. E., Martin, N. G., Montgomery, G. W., North, K. E., Pedersen, N. L., Spector, T. D., Speliotes, E. K., Goddard, M. E., Yang, J. & Visscher, P. M., Nov 2015, In: Nature Genetics. 47, 11, p. 1357-62, 2 unpag. Methods 8 p.

Research output: Contribution to journal › Letter › Research › peer-review

Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics

Rasmussen, Henrik Berg, Bjerre, D., Linnet, Kristian, Jürgens, G., Dalhoff, Kim, Stefansson, H., Hankemeier, T., Kaddurah-Daouk, R., Taboureau, O., Brunak, Søren, Houmann, T., Jeppesen, Pia, Pagsberg, Anne Katrine, Plessen, K., Dyrborg, J., Hansen, Peter Riis, Hansen, P. E., Hughes, T., Werge, Thomas & INDICES Consortium, I. C., Apr 2015, In: Pharmacogenomics. 16, 6, p. 649-65

Research output: Contribution to journal › Review › Research › peer-review

Usefulness of the SNP microarray technology to identify rare mutations in the case of perinatal death

Hoeffding, L. K., Kock, K. F., Johnsen, I. G., Hansen, Thomas Folkmann & Werge, Thomas, Jan 2015, In: Case Reports in Perinatal Medicine.

Research output: Contribution to journal › Journal article › Research › peer-review

Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates

Andersen, M. B., Croy, C. H., Dencker, D., Werge, Thomas, Bymaster, F. P., Felder, C. C. & Fink-Jensen, Anders, 2015, In: PLOS ONE. 10, 4, p. 1-13 13 p., e0122722.

Research output: Contribution to journal › Journal article › Research › peer-review

Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons

Mellerup, Erling Thyge, Andreassen, O. A., Bennike, B., Dam, H., Djurovic, S., Hansen, T., Jørgensen, Martin Balslev, Kessing, Lars Vedel, Koefoed, P., Melle, I., Mors, O., Werge, Thomas & Moeller, G. L., 2015, In: P L o S One. 10, 11, 7 p., e0143432.

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluating historical candidate genes for schizophrenia

Farrell, M. S., Werge, Thomas, Sklar, P., Owen, M. J., Ophoff, R. A., O'Donovan, M. C., Corvin, A., Cichon, S. & Sullivan, P. F., 2015, In: Molecular Psychiatry. 20, p. 555-62 8 p.

Research output: Contribution to journal › Review › Research › peer-review

Soluble Urokinase-Type Plasminogen Activator Receptor Levels in Patients With Schizophrenia

Nielsen, J., Røge, R., Pristed, S. G., Viuff, A. G., Ullum, H., Thørner, L. W., Werge, Thomas & Vang, T., 2015, In: Schizophrenia Bulletin. 41, 3, p. 764-71 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Danish 22q11 research initiative

Schmock, H., Vangkilde, A., Larsen, K. M., Fischer, E., Birknow, M. R., Jepsen, J. R. M., Olesen, C., Skovby, F., Plessen, K. J., Mørup, M., Hulme, O., Baaré, W. F. C., Didriksen, M., Siebner, Hartwig Roman, Werge, Thomas & Olsen, L., 2015, In: B M C Psychiatry. 15, p. 1-12 220.

Research output: Contribution to journal › Journal article › Research › peer-review

Common variant at 16p11.2 conferring risk of psychosis

Steinberg, S., de Jong, S., Mattheisen, M., Costas, J., Demontis, D., Jamain, S., Pietiläinen, O. P. H., Lin, K., Papiol, S., Huttenlocher, J., Sigurdsson, E., Vassos, E., Giegling, I., Breuer, R., Fraser, G., Walker, N., Melle, I., Djurovic, S., Agartz, I., Tuulio-Henriksson, A. & 31 others, Suvisaari, J., Lönnqvist, J., Paunio, T., Olsen, L., Hansen, T. F., Ingason, A., Pirinen, M., Strengman, E., Hougaard, D. M., Orntoft, T., Didriksen, M., Hollegaard, M. V., Nordentoft, Merete, Abramova, L., Kaleda, V., Arrojo, M., Sanjuán, J., Arango, C., Etain, B., Bellivier, F., Méary, A., Schürhoff, F., Szoke, A., Ribolsi, M., Magni, V., Siracusano, A., Sperling, S., Rossner, M., Christiansen, C., Werge, Thomas & GROUP, G., Jan 2014, In: Molecular Psychiatry. 19, 1, p. 108-114 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Sequence analysis of 17 NRXN1 deletions

Hoeffding, L. K. E., Hansen, T., Ingason, A., Doung, L., Thygesen, J. H., Møller, R. S., Tommerup, Niels, Kirov, G., Rujescu, D., Larsen, Lars Allan & Werge, Thomas, Jan 2014, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 165, 1, p. 52-61 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Quetiapine versus aripiprazole in children and adolescents with psychosis - protocol for the randomised, blinded clinical Tolerability and Efficacy of Antipsychotics (TEA) trial

Pagsberg, A. K., Jeppesen, P., Klauber, D. G., Jensen, K. G., Rudå, D., Stentebjerg-Olesen, M., Jantzen, P., Rasmussen, S., Saldeen, E. A-S., Lauritsen, M-B. G., Bilenberg, N., Stenstrøm, A. D., Pedersen, J., Nyvang, L., Madsen, S., Lauritsen, M. B., Vernal, D. L., Thomsen, P. H., Paludan, J., Werge, T. M. & 9 others, Winge, K., Juul, K., Gluud, C., Skoog, M., Wetterslev, J., Jepsen, J. R. M., Correll, C. U., Fink-Jensen, Anders & Fagerlund, Birgitte, 2014, In: B M C Psychiatry. 14, p. 1-13 13 p., 199.

Research output: Contribution to journal › Journal article › Research › peer-review

Psykiatrisk forskning bør have en central plads i langsigtede planer for psykiatrien

Nordentoft, Merete, Glenthøj, Birte Yding, Kessing, Lars Vedel, Parnas, Josef, Werge, Thomas, Bech, P., Fink-Jensen, Anders, Plessen, K., Simonsen, Erik, Nielsen, B., Bilenberg, N., Videbech, P., Rosenberg, R., Mors, O., Mortensen, P. B., Munk-Jørgensen, P., Hove Thomsen, P., Licht, R. & Seinhausen, C., 2 Sep 2013, In: Ugeskrift for Laeger. 175, 36, p. 2056-7 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Does Pharmacogenetic Testing for CYP450 2D6 and 2C19 among Patients with Diagnoses within the Schizophrenic Spectrum Reduce Treatment Costs?

Herbild, L., Andersen, S. E., Werge, Thomas, Rasmussen, H. B. & Jürgens, G., 4 Jun 2013, In: Basic & Clinical Pharmacology & Toxicology. 113, 4, p. 266–272 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Neuropeptide Y genes and suicidal behaviour among schizophrenic patients

Wang, August Gabriel, Koefoed, P., Jacoby, A. S., Woldbye, David Paul Drucker, Rasmussen, Henrik Berg, Timm, S., Dam, H., Jakobsen, K. D., Nordentoft, Merete, Jürgens, Gesche, Sorensen, H. J., Garsdal, O., Hvid, M. & Werge, Thomas, Jun 2013, In: Psychiatric Genetics. 23, 3, p. 139-40 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine

Esserlind, A., Christensen, A. F., Le, H., Kirchmann, M., Hauge, A. W., Toyserkani, N. M., Hansen, Torben, Grarup, Niels, Werge, Thomas, Steinberg, S., Bettella, F., Stefansson, H. & Olesen, Jes, May 2013, In: European Journal of Neurology. 20, 5, p. 765-772 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review