Thomas Werge
Clinical Professor
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Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
Kähler, A. K., Otnæss, M. K., Wirgenes, K. V., Hansen, T., Jönsson, E. G., Agartz, I., Hall, H., Werge, T., Morken, G., Mors, O., Mellerup, E., Dam, H., Koefoed, P., Melle, I., Steen, V. M., Andreassen, O. A., Djurovic, S., Kähler, A. K., Otnaess, M. K., Wirgenes, K. V. & 14 others, , 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 1, p. 86-96 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No association between DGKH and bipolar disorder in a Scandinavian case-control sample
Tesli, M., Kähler, A., Andreassen, B., Werge, T., Mors, O., Mellerup, E., Koefoed, P., Melle, I., Morken, G., Wirgenes, K., Andreassen, O., Djurovic, S., Tesli, M., Kähler, A. K., Andreassen, B. K., Werge, T., Mors, O., Mellerup, E., Koefoed, P., Melle, I. & 4 others, , 2009, In: Psychiatric Genetics. 19, 5, p. 269-72 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Den genetiske hjerne
Tommerup, N., Christensen, K. & Werge, Thomas, 2013, Den genetiske hjerne. Hjerneforum, 88 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Prenatal stress may increase vulnerability to life events: comparison with the effects of prenatal dexamethasone
Hougaard, Karin Sørig, Andersen, M. B., Kjaer, S. L., Hansen, Åse Marie, Werge, Thomas & Lund, S. P., 8 Sep 2005, In: Brain Research. 159, 1, p. 55-63 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quetiapine versus aripiprazole in children and adolescents with psychosis - protocol for the randomised, blinded clinical Tolerability and Efficacy of Antipsychotics (TEA) trial
Pagsberg, A. K., Jeppesen, P., Klauber, D. G., Jensen, K. G., Rudå, D., Stentebjerg-Olesen, M., Jantzen, P., Rasmussen, S., Saldeen, E. A-S., Lauritsen, M-B. G., Bilenberg, N., Stenstrøm, A. D., Pedersen, J., Nyvang, L., Madsen, S., Lauritsen, M. B., Vernal, D. L., Thomsen, P. H., Paludan, J., Werge, T. M. & 9 others, , 2014, In: B M C Psychiatry. 14, p. 1-13 13 p., 199.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic prediction of school performance in individuals with and without psychiatric disorders
Rajagopal, V. M., Trajberg, B. B., Grove, J., Horsdal, H. T., Petersen, L., Bulik, C. M., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Hougaard, D. M., Mors, O., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Agerbo, E., Borglum, A. D., Demontis, D. & iPSYCH-Broad Consortium, I. C., 2020, In: Behavior Genetics. 50, 6, p. 476-477 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The Duffy-null genotype and risk of infection
Legge, S. E., Christensen, R. H., Petersen, L., Pardiñas, A. F., Bracher-Smith, M., Knapper, S., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Mortensen, P. B., Owen, M. J., O'Donovan, M. C., Benros, Michael Eriksen & Walters, J. T. R., 2020, In: Human Molecular Genetics. 29, 20, p. 3341-3349 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses
Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, , 2020, In: Nature Communications. 11, 12 p., 6398.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study
Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Grove, J., Nordentoft, Merete, Børglum, A. D., Mortensen, P. B., Werge, Thomas, Melbye, M., Hougaard, D. M. & Christiansen, M., 2021, In: Journal of Neurodevelopmental Disorders. 13, 9 p., 19.Research output: Contribution to journal › Journal article › Research › peer-review
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Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
Satterstrom, F. K., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J. Y., Peng, M., Collins, R., Grove, J., Klei, L., Stevens, C., Reichert, J., Mulhern, M. S., Artomov, M., Gerges, S., Sheppard, B., Xu, X., Bhaduri, A., Norman, U., Brand, H. & 32 others, , 2020, In: Cell. 180, 3, p. 568-584.e23Research output: Contribution to journal › Journal article › Research › peer-review
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Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia
Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M., McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, Merete, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, Thomas, Svenning, J. C. & Horsdal, H. T., 2020, In: Schizophrenia Bulletin. 46, 6, p. 1629-1637 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., Carrera, N., Legge, S. E., Bishop, S., Cameron, D., Hamshere, M. L., Han, J., Hubbard, L., Lynham, A., Mantripragada, K., Rees, E., MacCabe, J. H., McCarroll, S. A., Baune, B. T., Breen, G., Byrne, E. M. & 51 others, , 2018, In: Nature Genetics. 50, p. 381-389Research output: Contribution to journal › Journal article › Research › peer-review
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Exploring Comorbidity Within Mental Disorders among a Danish National Population
Plana-Ripoll, O., Pedersen, C. B., Holtz, Y., Benros, M. E., Dalsgaard, S., De Jonge, P., Fan, C. C., Degenhardt, L., Ganna, A., Greve, A. N., Gunn, J., Iburg, K. M., Kessing, L. V., Lee, B. K., Lim, C. C. W., Mors, O., Nordentoft, M., Prior, A., Roest, A. M., Saha, S. & 12 others, , 2019, In: JAMA Psychiatry. 76, 3, p. 259-270Research output: Contribution to journal › Journal article › Research › peer-review
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Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
Haney, J. R., CommonMind Consortium, C. C., PsychENCODE Consortium, P. C. & iPSYCH-BROAD Working Group, I. W. G., 9 Feb 2018, In: Science. 359, 6376, p. 693-697 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comorbidities to restless legs syndrome – results from the Danish blood donor study
Didriksen, Maria, Hansen, T., Rigas, A., Allen, R., Burchell, B., Thørner, L., Nielsen, K., Di Angelantonio, E., Nielsen, M., Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, O., Paarup, H., Hjalgrim, H., Bruun, M., Burgdorf, K., Sørensen, E. & Ullum, H., 2017, In: Sleep Medicine. 40, Supplement 1, p. E79 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder
Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., Brikell, I., Ghirardi, L., Larsson, H., Lichtenstein, P., Eriksson, N., 23andMe Research Team, 2. R. T., Psychiatric Genomics Consortium: ADHD Subgroup, P. G. C. A. S., iPSYCH–Broad ADHD Workgroup, I. A. W., Werge, Thomas & Nordentoft, Merete, 15 Jun 2018, In: Biological Psychiatry. 83, 12, p. 1044-1053 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reliability of clinical ICD-10 schizophrenia diagnoses
Jakobsen, K. D., Nordgaard, Julie , Hansen, T., Jansson, Lennart Bertil, Parnas, Josef & Werge, Thomas, 2005, In: Nordic Journal of Psychiatry. 59, 3, p. 209-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility?
Hilker, R., Helenius, D., Fagerlund, B., Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 2017, In: EBioMedicine. 18, p. 320-326Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Srinivasan, S., Bettella, F., Mattingsdal, M., Wang, Y., Witoelar, A., Schork, A. J., Thompson, W. K., Zuber, V., Winsvold, B. S., Zwart, J., Collier, D. A., Desikan, R. S., Melle, I., Werge, Thomas, Dale, A. M., Djurovic, S., Andreassen, O. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, S. W. G. O. T. P. G. C. T. I. H. G. C., 15 Aug 2016, In: Biological Psychiatry. 80, 4, p. 284-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties
St Pourcain, B., Robinson, E. B., Anttila, V., Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., Zammit, S., Fisher, S. E., Neale, B. M., Anney, R. J. L., Ripke, S., Hollegaard, M. V., Werge, T., iPSYCH-SSI-Broad Autism Group, Ronald, A., Grove, J., Hougaard, D. M. & 4 others, , 2018, In: Molecular Psychiatry. 23, 2, p. 263-270Research output: Contribution to journal › Journal article › Research › peer-review
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Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates
Andersen, M. B., Croy, C. H., Dencker, D., Werge, Thomas, Bymaster, F. P., Felder, C. C. & Fink-Jensen, Anders, 2015, In: PLOS ONE. 10, 4, p. 1-13 13 p., e0122722.Research output: Contribution to journal › Journal article › Research › peer-review
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Gestational age-dependent development of the neonatal metabolome
Ernst, M., Rogers, S., Lausten-Thomsen, U., Björkbom, A., Laursen, S. S., Courraud, J., Borglum, A., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Hougaard, D. M. & Cohen, A. S., 2021, In: Pediatric Research. 89, p. 1396–1404 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic stratification of depression in UK Biobank
Howard, D. M., Folkersen, L., Coleman, J. R., Adams, M. J., Glanville, K., Werge, Thomas, Hagenaars, S. P., Han, B., Porteous, D., Campbell, A., Clarke, T., Breen, G., Sullivan, P. F., Wray, N. R., Lewis, C. M. & McIntosh, A. M., 2020, In: Translational Psychiatry. 10, 1, 8 p., 163.Research output: Contribution to journal › Journal article › Research › peer-review
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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. K., Adams, M. J., Clarke, T. K., McIntosh, A. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M. & 31 others, , 2020, In: Nature Communications. 11, 1, 2301.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Cell. 179, 7, p. 1469-1482 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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