Thomas Werge
Clinical Professor
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Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons
Mellerup, Erling Thyge, Andreassen, O. A., Bennike, B., Dam, H., Djurovic, S., Hansen, T., Jørgensen, Martin Balslev, Kessing, Lars Vedel, Koefoed, P., Melle, I., Mors, O., Werge, Thomas & Moeller, G. L., 2015, In: P L o S One. 10, 11, 7 p., e0143432.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of the genetic liability on the association between infections and autism
Shorter, J., Krebs, M., Ingason, A., Benros, Michael Eriksen, Thompson, W. & Werge, Thomas, Dec 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 719-720 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci
Foss-Skiftesvik, J., Hagen, C. M., Mathiasen, R., Adamsen, D., Bækvad-Hansen, M., Børglum, A. D., Nordentoft, Merete, Werge, Thomas, Christiansen, M., Schmiegelow, Kjeld, Juhler, Marianne, Mortensen, P. B., Hougaard, D. M. & Bybjerg-Grauholm, J., 2021, In: Child's Nervous System. 37, p. 819–830Research output: Contribution to journal › Journal article › Research › peer-review
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Comorbidity of migraine with ADHD in adults
Hansen, Thomas Folkmann, Hoeffding, L. K., Kogelman, L., Haspang, T. M., Ullum, H., Sørensen, E., Erikstrup, C., Pedersen, O. B., Nielsen, K. R., Hjalgrim, H., Paarup, H. M., Werge, Thomas & Burgdorf, K., 2018, In: BMC Neurology. 18, 1, p. 1-9 147.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study
Olsen, L., Sparsø, T., Weinsheimer, S. M., Dos Santos, M. B. Q., Mazin, W., Rosengren, A., Sanchez, X. C., Hoeffding, L. K., Schmock, H., Baekvad-Hansen, M., Bybjerg-Grauholm, J., Daly, M. J., Neale, B. M., Pedersen, M. G., Agerbo, E., Mors, O., Børglum, A., Nordentoft, M., Hougaard, D. M., Mortensen, P. B. & 4 others, , 2018, In: The Lancet Psychiatry. 5, 7, p. 573-580 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder
Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C., Thomson, P. A., Porteous, D., Campbell, A., Smith, B. H., Black, C., Padmanabhan, S., McIntosh, A. M., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M. & 32 others, , 2018, In: PLOS ONE. 13, 12, p. 1-29 e0209160.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes
Delio, M., Guo, T., McDonald-McGinn, D. M., Zackai, E., Herman, S., Kaminetzky, M., Higgins, A. M., Coleman, K., Chow, C., Jalbrzikowski, M., Jarlbrzkowski, M., Bearden, C. E., Bailey, A., Vangkilde, A., Olsen, L., Olesen, C., Skovby, F., Werge, T. M., Templin, L., Busa, T. & 38 others, , 7 Mar 2013, In: American Journal of Human Genetics. 92, 3, p. 439-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes
Forsingdal, A., Fejgin, K., Nielsen, V., Werge, Thomas & Nielsen, J., 2016, In: Translational Psychiatry. 6, 7, p. 1-9 9 p., e860.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., Grove, J., Maller, J., Samocha, K. E., Sanders, J-S. F., Ripke, S., Martin, J., Hollegaard, M. V., Werge, T., Hougaard, D. M., Neale, B. M., Evans, D. M., Skuse, D., Mortensen, P. B., Børglum, A. D., Ronald, A. & 3 others, , 2016, In: Nature Genetics. 48, 5, p. 552-5 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Investigation of SNP rs2060546 Immediately Upstream to NTN4 in a Danish Gilles de la Tourette Syndrome Cohort
Padmanabhuni, S. S., Houssari, R., Esserlind, A., Olesen, Jes, Werge, Thomas, Hansen, T. F., Bertelsen, B., Tsetsos, F., Paschou, P. & Tümer, Asuman Zeynep, Nov 2016, In: Frontiers in Neuroscience. 10, 7 p., 531.Research output: Contribution to journal › Journal article › Research › peer-review
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The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders
Pedersen, C. B., Bybjerg-Grauholm, J., Pedersen, M. G., Grove, J., Agerbo, E., Bækvad-Hansen, M., Poulsen, J. B., Hansen, C. S., McGrath, J. J., Als, T. D., Goldstein, J. I., Neale, B. M., Daly, M. J., Hougaard, D. M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Mortensen, P. B., 2018, In: Molecular Psychiatry. 23, p. 6-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic liability to major depression and risk of childhood asthma
Liu, X., Munk-Olsen, T., Albiñana, C., Vilhjálmsson, B. J., Pedersen, E. M., Schlünssen, V., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Hougaard, D. M., Mortensen, P. B. & Agerbo, E., 2020, In: Brain, Behavior, and Immunity. 89, p. 433-439 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
Bryois, J., Skene, N. G., Hansen, T. F., Kogelman, L. J. A., Watson, H. J., Liu, Z., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan, R., Alfredsson, L., Ando, T., Andreassen, O., Baker, J., Bergen, A., Berrettini, W., Birgegård, A., Boden, J., Boehm, I., Boni, C., Boraska Perica, V., Brandt, H. & 44 others, , May 2020, In: Nature Genetics. 52, p. 482-493Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB
Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, M. & 14 others, , 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 622-630Research output: Contribution to journal › Journal article › Research › peer-review
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The sequences of 150,119 genomes in the UK Biobank
Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F., Asgeirsdottir, M. & 27 others, , 2022, In: Nature. 607Research output: Contribution to journal › Journal article › Research › peer-review
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Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder
Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B., Ribasés, M. & 2 others, , 2022, In: Nature Genetics. 54, 8, p. 1117-1124 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci
Fadista, J., Skotte, L., Karjalainen, J., Abner, E., Sørensen, E., Ullum, H., Werge, Thomas, Esko, T., Milani, L., Palotie, A., Daly, M., Melbye, M., Feenstra, B., Geller, F., IPSYCH Grp, I. G. & FinnGen Consortium, F. C., 2022, In: Nature Communications. 13, 11 p., 3200.Research output: Contribution to journal › Journal article › Research › peer-review
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Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?
Jürgens, Gesche, Kaas-Hansen, Benjamin Skov, Nordentoft, Merete, Werge, Thomas & Andersen, Stig Ejdrup, Oct 2022, In: Journal of Personalized Medicine. 12, 10, 12 p., 1728.Research output: Contribution to journal › Journal article › Research › peer-review
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Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective
Nudel, R., Thompson, W. K., Børglum, A. D., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete & Benros, Michael Eriksen, Dec 2022, In: Translational Psychiatry. 12, 1, 9 p., 334.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R. & 19 others, , 2022, In: Brain. 145, 2, p. 555–568Research output: Contribution to journal › Journal article › Research › peer-review
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Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register
Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, Apr 2017, In: EBioMedicine. 18, p. 320-326Research output: Contribution to journal › Journal article › Research › peer-review
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COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark
Shen, Q., Joyce, E. E., Ebrahimi, O. V., Didriksen, M., Lovik, A., Sævarsdóttir, K. S., Magnúsdóttir, I., Mikkelsen, D. H., Unnarsdóttir, A. B., Hauksdóttir, A., Hoffart, A., Kähler, A. K., Thórdardóttir, E. B., Eythórsson, E., Frans, E. M., Tómasson, G., Ask, H., Hardardóttir, H., Jakobsdóttir, J., Lehto, K. & 12 others, , 2023, In: The Lancet Regional Health - Europe. 35, 12 p., 100756.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
HUNT All-In Psychiatry, H. A. P., 2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence of major depressive disorder in 51,658 otherwise healthy adult Danes: Sex differences in symptomatology and prediction of future anti-depressive medication
Mikkelsen, Christina, Larsen, M. A. H., Sørensen, E., Hansen, Thomas Folkmann, Mikkelsen, S., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Kessing, Lars Vedel, Werge, Thomas, Ullum, H., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Thørner, L. W. & Didriksen, Maria, 2022, In: Psychiatry Research. 318, 7 p., 114944.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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590
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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