Thomas Werge
Clinical Professor
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Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study
Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Geschwind, D. H., Buil Demur, Alfonso Alberto, Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, Thomas & Ingason, A., 2023, In: The Lancet Psychiatry. 10, 2, p. 129-138 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural basis of organic cation transporter-3 inhibition
Khanppnavar, B., Maier, J., Herborg, Freja, Gradisch, R., Lazzarin, E., Luethi, D., Yang, J. W., Qi, C., Holy, M., Jäntsch, K., Kudlacek, O., Schicker, K., Werge, Thomas, Gether, Ulrik, Stockner, T., Korkhov, V. M. & Sitte, H. H., 2022, In: Nature Communications. 13, 1, 13 p., 6714.Research output: Contribution to journal › Journal article › Research › peer-review
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Accurate and Effective Detection of Recurrent Copy Number Variants in Large SNP Genotype Datasets
Montalbano, S., Sánchez, X. C., Vaez, M., Helenius, D., Werge, Thomas & Ingason, A., 2022, In: Current Protocols. 2, 12, 21 p., e621.Research output: Contribution to journal › Journal article › Research › peer-review
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Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration
Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A., Rossi, R. M. & 54 others, , 2 Sep 2019, In: Nature Communications. 10, 1, 13 p., 3927.Research output: Contribution to journal › Journal article › Research › peer-review
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A polygenic resilience score moderates the genetic risk for schizophrenia
Hess, J. L., Tylee, D. S., Mattheisen, M., The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum, A. D., Als, T. D., Grove, J., Werge, T., Mortensen, P. B., Mors, O., Nordentoft, M., Hougaard, D. M., Byberg-grauholm, J., Bækvad-hansen, M., Greenwood, T. A., Tsuang, M. T., Curtis, D., Steinberg, S., Sigurdsson, E. & 6 others, , 2021, In: Molecular Psychiatry. 26, p. 800–815Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
ADHD Working Group of the Psychiatric Genomics Consortium (PGC), A. W. G. O. T. P. G. C. (., Jan 2019, In: Nature Genetics. 51, 1, p. 63-75 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Large recurrent microdeletions associated with schizophrenia
Stefansson, H., Rujescu, D., Cichon, S., Pietilainen, O. P., Ingason, A., Steinberg, S., Fossdal, R., Sigurdsson, E., Sigmundsson, T., Buizer-Voskamp, J. E., Hansen, T., Jakobsen, K. D., Muglia, P., Francks, C., Matthews, P. M., Gylfason, A., Halldorsson, B. V., Gudbjartsson, D., Thorgeirsson, T. E., Sigurdsson, A. & 31 others, , 2008, In: Nature Study. 455, 7210, p. 232-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction
Togsverd, M., Tanko, L. B., Bagger, Y. Z., Hansen, T., Qin, G., Christiansen, C., Rasmussen, H. B. & Werge, Thomas, 2008, In: Journal of Affective Disorders. 106, 1-2, p. 169-172 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S., Andreassen, O. A., Werge, T., Hall, H., Agartz, I., Terenius, L., Jönsson, E. G., Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S. & 6 others, , 2009, In: Psychiatric Genetics. 19, 5, p. 273-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Disruption of the neurexin 1 gene is associated with schizophrenia
Rujescu, D., Ingason, A., Cichon, S., Pietiläinen, O. P. H., Barnes, M. R., Toulopoulou, T., Picchioni, M., Vassos, E., Ettinger, U., Bramon, E., Murray, R., Ruggeri, M., Tosato, S., Bonetto, C., Steinberg, S., Sigurdsson, E., Sigmundsson, T., Petursson, H., Gylfason, A., Olason, P. I. & 31 others, , 2009, In: Human Molecular Genetics. 18, 5, p. 988-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
Djurovic, S., Le Hellard, S., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G., Rasmussen, H. B., Melle, I., Werge, T., Andreassen, O. A., Djurovic, S., Le Hellard, S., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G. & 4 others, , 2009, In: Psychiatry Research. 168, 3, p. 256-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of association of the serotonin transporter gene promoter region polymorphism, 5-HTTLPR, including rs25531 with cigarette smoking and alcohol consumption
Rasmussen, H., Bagger, Y., Tanko, L. B., Christiansen, C., Werge, Thomas, Rasmussen, H., Bagger, Y., Tanko, L. B., Christiansen, C. & Werge, Thomas, 2009, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 150B, 4, p. 575-80 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Suicidal Behavior and the Serotonin Transporter Gene Polymorphism (5-HTTLPR) with Novel Subtypes, in Danish Schizophrenic Patients
Wang, August Gabriel, Rasmussen, Henrik Berg, Sørensen, H. J., Hvid, M., Breddam, C. H., Hansen, B., Bille, V. H., Garsdal, O., Jacoby, A., Søbye, K., Dam, O. H., Krogsbøl, H., Timm, S. & Werge, Thomas, 2009, In: Open Psychiatry Journal.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
Anttila, V., Stefansson, H., Kallela, M., Todt, U., Terwindt, G. M., Calafato, M. S., Nyholt, D. R., Dimas, A. S., Freilinger, T., Müller-Myhsok, B., Artto, V., Inouye, M., Alakurtti, K., Kaunisto, M. A., Hämäläinen, E., de Vries, B., Stam, A. H., Weller, C. M., Heinze, A., Heinze-Kuhn, K. & 31 others, , 1 Oct 2010, In: Nature Genetics. 42, 10, p. 869-73 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
Haukvik, U. K., Saetre, P., McNeil, T., Bjerkan, P. S., Andreassen, O. A., Werge, Thomas, Jönsson, E. G. & Agartz, I., 1 Oct 2010, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34, 7, p. 1259-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutations in NRXN1 in a family multiply affected with brain disorders: NRXN1 mutations and brain disorders
Duong, L., Klitten, L. L., Møller, R. S., Ingason, A., Jakobsen, K. D., Skjødt, C., Didriksen, M., Hjalgrim, H., Werge, Thomas & Tommerup, Niels, Apr 2012, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 159B, 3, p. 354-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
Caprini, S., Saetre, P., Melle, I., Djurovic, S., Andreassen, O. A., Skjødt, C., Doung, L., Werge, Thomas, Hall, H., Agartz, I., Terenius, L. & Jönsson, E. G., 1 Aug 2011, In: Psychiatric Genetics. 21, 4, p. 214-5 2 p.Research output: Contribution to journal › Letter › Research › peer-review
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Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls
Holtze, M., Saetre, P., Engberg, G., Schwieler, L., Werge, Thomas, Andreassen, O. A., Hall, H., Terenius, L., Agartz, I., Jönsson, E. G., Schalling, M. & Erhardt, S., 2012, In: Journal of Psychiatry and Neuroscience. 37, 1, p. 53-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reliability of clinical ICD-10 diagnoses among electroconvulsive therapy patients with chronic affective disorders
Jakobsen, K. D., Hansen, T. F., Dam, H., Larsen, E. B., Gether, Ulrik & Werge, Thomas, 2008, In: European Journal of Psychiatry. 22, 3, p. 161-172 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
Vassos, E., Steinberg, S., Cichon, S., Breen, G., Sigurdsson, E., Andreassen, O. A., Djurovic, S., Morken, G., Grigoroiu-Serbanescu, M., Diaconu, C. C., Czerski, P. M., Hauser, J., Babadjanova, G., Abramova, L. I., Mühleisen, T. W., Nöthen, M. M., Rietschel, M., McGuffin, P., St Clair, D., Gustafsson, O. & 28 others, , 2012, In: Biological Psychiatry. 72, 8, p. 645-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of postnatal anoxia on striatal dopamine metabolism and prepulse inhibition in rats
Sandager-Nielsen, K., Andersen, M. B., Sager, T. N., Werge, Thomas & Scheel-Krüger, J., 2004, In: Pharmacology, Biochemistry and Behavior. 77, 4, p. 767-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Submikroskopiske kromosomanomalier som årsag til skizofreni
Hansen, T., Ingason, A. & Werge, Thomas, 2008, In: Ugeskrift for Laeger. 170, 46, p. 3773-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms
Fanous, A. H., Zhou, B., Aggen, S. H., Bergen, S. E., Amdur, R. L., Duan, J., Sanders, A. R., Shi, J., Mowry, B. J., Olincy, A., Amin, F., Cloninger, C. R., Silverman, J. M., Buccola, N. G., Byerley, W. F., Black, D. W., Freedman, R., Dudbridge, F., Holmans, P. A., Ripke, S. & 8 others, , 2012, In: American Journal of Psychiatry. 169, 12, p. 1309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics
Rasmussen, Henrik Berg, Bjerre, D., Linnet, Kristian, Jürgens, G., Dalhoff, Kim, Stefansson, H., Hankemeier, T., Kaddurah-Daouk, R., Taboureau, O., Brunak, Søren, Houmann, T., Jeppesen, Pia, Pagsberg, Anne Katrine, Plessen, K., Dyrborg, J., Hansen, Peter Riis, Hansen, P. E., Hughes, T., Werge, Thomas & INDICES Consortium, I. C., Apr 2015, In: Pharmacogenomics. 16, 6, p. 649-65Research output: Contribution to journal › Review › Research › peer-review
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Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family
Duong, L. T. T., Hoeffding, L. K., Petersen, K. B., Knudsen, C. D., Thygesen, J. H., Klitten, L. L., Tommerup, Niels, Ingason, A. & Werge, Thomas, Dec 2015, In: European Journal of Medical Genetics. 58, 12, p. 650-653 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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590
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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