Thomas Werge
Clinical Professor
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No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study
Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A. D., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D. W., Mowry, B. J., Müller-Mhysok, B., Neale, B. M. & 297 others, , Oct 2016, In: PLOS Genetics. 12, 10, 20 p., e1006343.Research output: Contribution to journal › Journal article › Research › peer-review
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Schizophrenia Spectrum Disorders in a Danish 22q11.2 Deletion Syndrome Cohort Compared to the Total Danish Population—A Nationwide Register Study
Vangkilde, A., Olsen, L., Hoeffding, L. K. E., Pedersen, C. B., Mortensen, P. B., Werge, Thomas & Trabjerg, B., May 2016, In: Schizophrenia Bulletin. 42, 3, p. 824-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neuropeptide Y genes and suicidal behaviour among schizophrenic patients
Wang, August Gabriel, Koefoed, P., Jacoby, A. S., Woldbye, David Paul Drucker, Rasmussen, Henrik Berg, Timm, S., Dam, H., Jakobsen, K. D., Nordentoft, Merete, Jürgens, Gesche, Sorensen, H. J., Garsdal, O., Hvid, M. & Werge, Thomas, Jun 2013, In: Psychiatric Genetics. 23, 3, p. 139-40 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Population genomics of the Viking world: [incl. correction]
Margaryan, A., Lawson, D. J., Sikora, M., Racimo, F., Rasmussen, S., Moltke, I., Cassidy, L. M., Jørsboe, E., Ingason, A., Pedersen, M. W., Korneliussen, T., Wilhelmson, H., Buś, M. M., de Barros Damgaard, P., Martiniano, R., Renaud, G., Bhérer, C., Moreno-Mayar, J. V., Fotakis, A. K., Allen, M. & 30 others, , 2020, In: Nature. 585, 7825, p. 390-396 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GENETIC SUBTYPES OF SCHIZOPHRENIA ELUCIDATED BY MULTISTATE DIAGNOSIS TRAJECTORIES
Themudo, G. E., Krebs, M., Benros, Michael Eriksen, Werge, Thomas & Thompson, W., 2019, p. 1338-1338.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Cohort Profile: The Danish Blood Donor Study
Erikstrup, C., Sørensen, E., Nielsen, K. R., Bruun, M. T., Petersen, M. S., Rostgaard, K., Thørner, L. W., Larsen, M., Mikkelsen, S., Dinh, K. M., Schwinn, M., Rigas, A. S., Didriksen, M., Dowsett, J., von Stemann, J. H., Brodersen, T., Paulsen, I. W., Hindhede, L., Sækmose, S. G., Kaspersen, K. A. & 10 others, , 2023, In: International Journal of Epidemiology. 52, 3, p. e162-e171 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomisk medicin som forbrugervare
Folkersen, L. & Werge, Thomas, 2019, In: Ugeskrift for Laeger. 181, 5 p., V11180789.Research output: Contribution to journal › Journal article › Research › peer-review
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A major role for common genetic variation in anxiety disorders
Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O., Bo Mortensen, P. & 6 others, , 2020, In: Molecular Psychiatry. 25, p. 3292–3303Research output: Contribution to journal › Journal article › Research › peer-review
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Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 46 others, , 2021, In: Molecular Psychiatry. 26, p. 2457–2470 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic risk and progression to bipolar or psychotic disorders among individuals diagnosed with unipolar depression in early life
Musliner, K. L., Krebs, M. D., Albiñana, C., Vilhjalmsson, B., Agerbo, E., Zandi, P. P., Hougaard, D. M., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Mortensen, P. B. & Østergaard, S. D., 2020, In: American Journal of Psychiatry. 177, 10, p. 936-943 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Population Genomics of Stone Age Eurasia
Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., Mota, B., Paulsson, B. S., Halgren, A., Macleod, R., Schjellerup Jørkov, M. L., Demeter, F., Novosolov, M., Sørensen, L., Nielsen, P-O., Henriksen, R. H. A. & 143 others, , 2022, p. 1-71, (bioRxiv).Research output: Working paper › Preprint › Research
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Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations
Unnarsdóttir, A. B., Lovik, A., Fawns-Ritchie, C., Ask, H., Kõiv, K., Hagen, K., Didriksen, M., Christoffersen, L. A. N., Garðarsson, A. B., McIntosh, A., Kähler, A. K., Campbell, A., Hauksdóttir, A., Erikstrup, C., Mikkelsen, D. H., Altschul, D., Thordardottir, E. B., Frans, E. M., Kvale, G., Tómasson, G. & 32 others, , 2022, In: International Journal of Epidemiology. 51, 3, p. e108–e122 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C. Y., Dennison, C. A., Hall, L. S., Lam, M., Watanabe, K., Frei, O., Ge, T., Harwood, J. C., Koopmans, F., Magnusson, S., Richards, A. L., Sidorenko, J., Wu, Y. & 35 others, , 2022, In: Nature. 604, 7906, p. 502-508 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register
Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 15 Mar 2018, In: Biological Psychiatry. 83, 6, p. 492-498Research output: Contribution to journal › Journal article › Research › peer-review
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Population genomics of post-glacial western Eurasia
Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., da Mota, B. S., Paulsson, B. S., Halgren, A., Macleod, R., Jørkov, M. L. S., Demeter, F., Sørensen, L., Nielsen, P. O., Henriksen, R. A., Vimala, T. & 144 others, , 2024, In: Nature. 625, 7994, p. 301-311Research output: Contribution to journal › Journal article › Research › peer-review
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Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses
Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G., Thorgeirsson, T. & 23 others, , 2023, In: Nature Medicine. 29, 7, p. 1832-1844 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder
Dahl, A., Thompson, M., An, U., Krebs, M., Appadurai, V., Border, R., Bacanu, S., Werge, Thomas, Flint, J., Schork, A. J., Sankararaman, S., Kendler, K. S. & Cai, N., 2023, In: Nature Genetics. 55, 12, p. 2082-2093Research output: Contribution to journal › Journal article › Research › peer-review
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A study of the genetic architecture of social responsiveness in families with parental schizophrenia or bipolar disorder and population-based controls
Veddum, L., Greve, A. N., Gregersen, M., Andreassen, A. K., Knudsen, C. B., Brandt, J. M., Krantz, M. F., Søndergaard, A., Burton, B. K., Jepsen, J. R. M., Hemager, N., Werge, Thomas, Thorup, Anne, Nordentoft, Merete, Mors, O. & Nudel, R., 2023, In: Psychiatry Research. 326, 115280.Research output: Contribution to journal › Journal article › Research › peer-review
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Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, , 2022, In: Biological Psychiatry. 91, 1, p. 107-117Research output: Contribution to journal › Journal article › Research › peer-review
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Association and genetic overlap between clinical chemistry tests and migraine
Tanha, H. M. & The International Headache Genetics Consortium (IHGC), T. I. H. G. C. (., 2021, In: Cephalalgia. 41, 11-12, p. 1208-1221 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Relationship Between Major Depressive Disorder (Mdd) Symptoms and Mdd Heterogeneity
Huang, L., Tang, S., Krebs, M. D., Schork, A. J., Werge, Thomas, Dahl, A., Zuber, V. & Cai, N., 2021, In: Genetic Epidemiology. 45, 7, p. 761-761 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
Bjornsdottir, G., Stefansdottir, L., Thorleifsson, G., Sulem, P., Norland, K., Ferkingstad, E., Oddsson, A., Zink, F., Lund, S. H., Nawaz, M. S., Bragi Walters, G., Skuladottir, A. T., Gudjonsson, S. A., Einarsson, G., Halldorsson, G. H., Bjarnadottir, V., Sveinbjornsson, G., Helgadottir, A., Styrkarsdottir, U., Gudmundsson, L. J. & 26 others, , 2022, In: Nature Communications. 13, 13 p., 634.Research output: Contribution to journal › Journal article › Research › peer-review
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Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants
Nudel, R., Appadurai, V., Buil, A., Nordentoft, Merete & Werge, Thomas, 2021, In: Journal of Neurodevelopmental Disorders. 13, 15 p., 54.Research output: Contribution to journal › Journal article › Research › peer-review
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GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS. O4.6.
Benros, Michael Eriksen, Nudel, R., Wang, Y., Appadurai, V., Schork, A., Agerbo, E., Werge, Thomas, Nordentoft, Merete, Mortensen, P., Buil, A. & Thompson, W., 2018, In: Schizophrenia Bulletin. 44, Suppl. 1, p. S85 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Accumulation of Disadvantages Across Multiple Domains Amongst Subgroups of Children of Parents with Schizophrenia or Bipolar Disorder: Clustering Data from the Danish High Risk and Resilience Study VIA 7
Krantz, M. F., Ellersgaard, D., Andersen, K. K., Hemager, N., Christiani, C., Spang, K. S., Burton, B. K., Gregersen, M., Søndergaard, A., Greve, A., Gantriis, D. L., Ohland, J., Mortensen, P. B., Werge, T., Nudel, R., Wang, Y., Hougaard, D. M., Plessen, K. J., Bliksted, V., Jepsen, J. R. M. & 3 others, , 2022, In: Schizophrenia Bulletin Open. 3, 1, 16 p., sgac010.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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590
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
Published