Thomas Werge
Clinical Professor
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Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study
Erlangsen, A., Appadurai, V., Wang, Y., Turecki, G., Mors, O., Werge, Thomas, Mortensen, P. B., Starnawska, A., Børglum, A. D., Schork, A., Nudel, R., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Thompson, W. K., Nordentoft, Merete & Agerbo, E., 2020, In: Molecular Psychiatry. 25, p. 2410–2421Research output: Contribution to journal › Journal article › Research › peer-review
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Human Disease Variation in the Light of Population Genomics
Prohaska, Ana, Racimo, Fernando, Schork, A. J., Sikora, Martin, Stern, A. J., Ilardo, M., Allentoft, Morten Erik, Folkersen, L., Buil, A., Moreno Mayar, J. Víctor, Korneliussen, Thorfinn Sand, Geschwind, D., Ingason, A., Werge, Thomas, Nielsen, Rasmus & Willerslev, Eske, 2019, In: Cell. 177, 1, p. 115-131 17 p.Research output: Contribution to journal › Review › Research › peer-review
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Language deficits in specific language impairment, attention deficit/hyperactivity disorder, and autism spectrum disorder: An analysis of polygenic risk
Nudel, R., Christiani, C. A. J., Ohland, J., Uddin, M. J., Hemager, N., Ellersgaard, D. V., Spang, K. S., Burton, B. K., Greve, A. N., Gantriis, D. L., Bybjerg-Grauholm, J., Jepsen, J. R. M., Thorup, Anne, Mors, O., Nordentoft, Merete & Werge, Thomas, 2020, In: Autism Research. 13, 3, p. 369-381Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation screening of the glutamate cysteine ligase modifier (GCLM) gene in patients with schizophrenia
Butticaz, C., Werge, Thomas, Beckmann, J. S., Cuénod, M., Do, K. Q., Rivolta, C., Butticaz, C., Werge, Thomas, Beckmann, J. S., Cuénod, M., Do, K. Q. & Rivolta, C., 2009, In: Psychiatric Genetics. 19, 4, p. 201-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interaction between genetic polymorphisms and stressful life events in first episode depression
Bukh, Jens Otto Drachmann, Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In: Journal of Affective Disorders. 119, 1-3, p. 107-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CYP2D6 genotype predicts antipsychotic side effects in schizophrenia inpatients: a retrospective matched case-control study
Kobylecki, C. J., Jakobsen, K. D., Hansen, T., Jakobsen, I. V., Rasmussen, H. B., Werge, Thomas, Kobylecki, C. J., Jakobsen, K. D., Hansen, T., Jakobsen, I. V., Rasmussen, H. B. & Werge, Thomas, 2009, In: Neuropsychobiology. 59, 4, p. 222-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events
Haastrup, E., Bukh, Jens Otto Drachmann, Bock, C., Vinberg, Maj, Thørner, L. W., Hansen, T., Werge, Thomas, Kessing, Lars Vedel & Ullum, H., 2012, In: Journal of Affective Disorders. 136, 1-2, p. 134-138 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Koefoed, P., Woldbye, D. P. D., Hansen, T. V. O., Eplov, L. F., Christiansen, S. H. O., Mors, O., Kessing, L. V., Werge, T., Kaipio, K., Pesonen, U., Fahmy, T., Mellerup, E. T., Jakobsen, K. D., Hansen, E. S., Knudsen, G. M., Bukh, J. D., Bock, C., Lindberg, C., Kristensen, A. S., Dam, H. & 6 others, , 23 Mar 2012, In: Acta Neuropsychiatrica. 24, 2, p. 81-90 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sequence analysis of 17 NRXN1 deletions
Hoeffding, L. K. E., Hansen, T., Ingason, A., Doung, L., Thygesen, J. H., Møller, R. S., Tommerup, Niels, Kirov, G., Rujescu, D., Larsen, Lars Allan & Werge, Thomas, Jan 2014, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 165, 1, p. 52-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The substituted (S)-3-phenylpiperidine (-)-OSU6162 reduces apomorphine- and amphetamine-induced behaviour in Cebus apella monkeys
Brandt-Christensen, M., Andersen, M. B., Fink-Jensen, Anders, Werge, Thomas & Gerlach, J., 2006, In: Journal of Neural Transmission. 113, 1, p. 11-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the 120-bp duplication in the dopamine D4 receptor gene and schizophrenia in a sample of Danish subjects
Olsen, L., Timm, S., Wang, August Gabriel, Søeby, K., Jakobsen, K. D., Clemmensen, S., Løkke, A., Fossum, M., Parnas, Josef, Hemmingsen, R. P. A., Rasmussen, H. B. & Werge, Thomas, 2005, In: Schizophrenia Research. 73, 1, p. 133-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Common variant at 16p11.2 conferring risk of psychosis
Steinberg, S., de Jong, S., Mattheisen, M., Costas, J., Demontis, D., Jamain, S., Pietiläinen, O. P. H., Lin, K., Papiol, S., Huttenlocher, J., Sigurdsson, E., Vassos, E., Giegling, I., Breuer, R., Fraser, G., Walker, N., Melle, I., Djurovic, S., Agartz, I., Tuulio-Henriksson, A. & 31 others, , Jan 2014, In: Molecular Psychiatry. 19, 1, p. 108-114 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genotyping of the 19-bp insertion/deletion polymorphism in the 5' flank of beta-hydroxylase gene by dissociation analysis of allele-specific PCR products
Rasmussen, H. B. & Werge, Thomas, 2005, In: Clinical Chemistry and Laboratory Medicine. 43, 9, p. 903-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 2012, In: European Archives of Psychiatry and Clinical Neuroscience. 262, 7, p. 549-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study of multiplex schizophrenia pedigrees
Levinson, D. F., Shi, J., Wang, K., Oh, S., Riley, B., Pulver, A. E., Wildenauer, D. B., Laurent, C., Mowry, B. J., Gejman, P. V., Owen, M. J., Kendler, K. S., Nestadt, G., Schwab, S. G., Mallet, J., Nertney, D., Sanders, A. R., Williams, N. M., Wormley, B., Lasseter, V. K. & 28 others, , Sep 2012, In: American Journal of Psychiatry. 169, 9, p. 963-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cognitive performance in elderly women: significance of the 19bp insertion/deletion polymorphism in the 5' flank of the dopamine beta-hydroxylase gene, educational level, body fat measures, serum triglyceride, alcohol consumption and age
Togsverd, M., Werge, Thomas, Tankó, L. B., Bagger, Y. Z., Qin, G. G., Hansen, T., Christiansen, C. & Rasmussen, H. B., 2007, In: International Journal of Geriatric Psychiatry. 22, 9, p. 883-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects
Passos Gregorio, S., Gattaz, W. F., Tavares, H., Kieling, C., Timm, S., Wang, August Gabriel, Berg Rasmussen, H., Werge, Thomas & Dias-Neto, E., 2006, In: Schizophrenia Research. 88, 1-3, p. 275-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Brain expressed microRNAs implicated in schizophrenia etiology
Hansen, T., Olsen, L., Lindow, M., Jakobsen, K. D., Ullum, H., Jonsson, E., Andreassen, O. A., Djurovic, S., Melle, I., Agartz, I., Hall, H., Timm, S., Wang, August Gabriel & Werge, Thomas, 2007, In: P L o S One. 2, 9, p. e873Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 34 others, , 2017, In: Nature Communications. 8, 13 p., 910.Research output: Contribution to journal › Journal article › Research › peer-review
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Psykiatrisk forskning bør have en central plads i langsigtede planer for psykiatrien
Nordentoft, Merete, Glenthøj, Birte Yding, Kessing, Lars Vedel, Parnas, Josef, Werge, Thomas, Bech, P., Fink-Jensen, Anders, Plessen, K., Simonsen, Erik, Nielsen, B., Bilenberg, N., Videbech, P., Rosenberg, R., Mors, O., Mortensen, P. B., Munk-Jørgensen, P., Hove Thomsen, P., Licht, R. & Seinhausen, C., 2 Sep 2013, In: Ugeskrift for Laeger. 175, 36, p. 2056-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Population genetic differentiation of height and body mass index across Europe
Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., Powell, J. E., Vinkhuyzen, A., Berndt, S. I., Gustafsson, S., Justice, A. E., Kahali, B., Locke, A. E., Pers, T. H., Vedantam, S., Wood, A. R., van Rheenen, W., Andreassen, O. A., Gasparini, P., Metspalu, A. & 23 others, , Nov 2015, In: Nature Genetics. 47, 11, p. 1357-62, 2 unpag. Methods 8 p.Research output: Contribution to journal › Letter › Research › peer-review
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Association of AADAC Deletion and Gilles de la Tourette Syndrome in a Large European Cohort
Bertelsen, B., Stefánsson, H., Riff Jensen, L., Melchior, L., Debes, N. M., Groth, C., Skov, L., Werge, T., Karagiannidis, I., Tarnok, Z., Barta, C., Nagy, P., Farkas, L., Brøndum-Nielsen, K., Rizzo, R., Gulisano, M., Rujescu, D., Kiemeney, L. A., Tosato, S., Nawaz, M. S. & 14 others, , 1 Mar 2016, In: Biological Psychiatry. 79, 5, p. 383–391 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The genetic architecture of sporadic and multiple consecutive miscarriage
Laisk, T., Soares, A. L. G., Ferreira, T., Painter, J. N., Censin, J. C., Laber, S., Bacelis, J., Chen, C. Y., Lepamets, M., Lin, K., Liu, S., Millwood, I. Y., Ramu, A., Southcombe, J., Andersen, M. S., Yang, L., Becker, C. M., Børglum, A. D., Gordon, S. D., Bybjerg-Grauholm, J. & 35 others, , 2020, In: Nature Communications. 11, 5980.Research output: Contribution to journal › Journal article › Research › peer-review
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Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status
Agerbo, E., Trabjerg, B. B., Børglum, A. D., Schork, A. J., Vilhjálmsson, B. J., Pedersen, C. B., Hakulinen, C., Albiñana, C., Hougaard, D. M., Grove, J., McGrath, J. J., Bybjerg-Grauholm, J., Mors, O., Plana-Ripoll, O., Werge, Thomas, Wray, N. R., Mortensen, P. B. & Musliner, K. L., 2021, In: JAMA Psychiatry. 78, 4, p. 387-397 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Complement genes contribute sex-biased vulnerability in diverse disorders
Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., Taylor, K. E., Whelan, C. W., Tombleson, P., Loohuis, L. M. O., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H. & 33 others, , 2020, In: Nature. 582, 7813, p. 577-581 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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588
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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